Patrick Casey Seed

  • 2898 Citations
1995 …2021
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Research Output 1995 2019

  • 2898 Citations
  • 58 Article
  • 6 Review article
  • 2 Comment/debate
  • 1 Short survey
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Article
2019

Disrupted Maturation of the Microbiota and Metabolome among Extremely Preterm Infants with Postnatal Growth Failure

Younge, N. E., Newgard, C. B., Cotten, C. M., Goldberg, R. N., Muehlbauer, M. J., Bain, J. R., Stevens, R. D., O’Connell, T. M., Rawls, J. F., Seed, P. C. & Ashley, P. L., Dec 1 2019, In : Scientific Reports. 9, 1, 8167.

Research output: Contribution to journalArticle

Open Access
Extremely Premature Infants
Metabolome
Microbiota
Growth
Premature Infants
1 Citation (Scopus)

Reduction in Mortality after Umbilical Cord Blood Transplantation in Children Over a 20-Year Period (1995-2014)

Spees, L. P., Martin, P. L., Kurtzberg, J., Stokhuyzen, A., McGill, L., Prasad, V. K., Driscoll, T. A., Parikh, S. H., Page, K. M., Vinesett, R., Severyn, C., Sung, A. D., Proia, A. D., Jenkins, K., Arshad, M., Steinbach, W. J., Seed, P. C. & Kelly, M. S., Apr 1 2019, In : Biology of Blood and Marrow Transplantation. 25, 4, p. 756-763 8 p.

Research output: Contribution to journalArticle

Fetal Blood
Transplantation
Mortality
Aspergillosis
Graft vs Host Disease
5 Citations (Scopus)

The microbiome in patients with atopic dermatitis

Paller, A., Kong, H. H., Seed, P. C., Naik, S., Scharschmidt, T. C., Gallo, R. L., Luger, T. & Irvine, A. D., Jan 1 2019, In : Journal of Allergy and Clinical Immunology. 143, 1, p. 26-35 10 p.

Research output: Contribution to journalArticle

Microbiota
Atopic Dermatitis
Skin
Methylobacteriaceae
Immune System
Risk Management
Urinary Tract Infections
Vaccinium macrocarpon
Bacterial Adhesion
Anti-Bacterial Agents
2018
7 Citations (Scopus)

Antimicrobial photodynamic therapy mediated by methylene blue and potassium iodide to treat urinary tract infection in a female rat model

Huang, Y. Y., Wintner, A., Seed, P. C., Brauns, T., Gelfand, J. A. & Hamblin, M. R., Dec 1 2018, In : Scientific Reports. 8, 1, 7257.

Research output: Contribution to journalArticle

Potassium Iodide
Methylene Blue
Photochemotherapy
Urinary Tract Infections
Uropathogenic Escherichia coli
Glycogen Storage Disease Type II
Clostridium difficile
Clostridium Infections
Morbidity
Metronidazole
2 Citations (Scopus)

Copper Influences the Antibacterial Outcomes of a β-Lactamase-Activated Prochelator against Drug-Resistant Bacteria

Zaengle-Barone, J. M., Jackson, A. C., Besse, D. M., Becken, B., Arshad, M., Seed, P. C. & Franz, K. J., Jun 8 2018, In : ACS Infectious Diseases. 4, 6, p. 1019-1029 11 p.

Research output: Contribution to journalArticle

Copper
Bacteria
Pharmaceutical Preparations
Metals
Anti-Bacterial Agents

Early-life skin microbiota in hospitalized preterm and full-term infants

Younge, N. E., Araújo-Pérez, F., Brandon, D. & Seed, P. C., May 31 2018, In : Microbiome. 6, 1, 1 p.

Research output: Contribution to journalArticle

Microbiota
Skin
Escherichia
Staphylococcus
Enterobacter

Pneumococcal Colonization and the Nasopharyngeal Microbiota of Children in Botswana

Kelly, M. S., Surette, M. G., Smieja, M., Rossi, L., Luinstra, K., Steenhoff, A. P., Goldfarb, D. M., Pernica, J. M., Arscott-Mills, T., Boiditswe, S., Mazhani, T., Rawls, J. F., Cunningham, C. K., Shah, S. S., Feemster, K. A. & Seed, P. C., Nov 1 2018, In : The Pediatric infectious disease journal. 37, 11, p. 1176-1183 8 p.

Research output: Contribution to journalArticle

Botswana
Microbiota
Streptococcus pneumoniae
Pneumococcal Infections
Moraxella

Predominant bacteria and patterns of antibiotic susceptibility in urinary tract infection in children with spina bifida

Ortiz, T. K., Velazquez, N., Ding, L., Routh, J. C., Wiener, J. S., Seed, P. C. & Ross, S. S., Oct 1 2018, In : Journal of Pediatric Urology. 14, 5, p. 444.e1-444.e8

Research output: Contribution to journalArticle

Spinal Dysraphism
Urinary Tract Infections
Anti-Bacterial Agents
Bacteria
Pediatrics

The relationship of cervical microbiota diversity with race and disparities in preterm birth

Wheeler, S., Pryor, K., Antczak, B., Truong, T., Murtha, A. & Seed, P. C., Jan 1 2018, In : Journal of Neonatal-Perinatal Medicine. 11, 3, p. 231-239 9 p.

Research output: Contribution to journalArticle

Microbiota
Premature Birth
Pregnancy
Therapeutic Irrigation
Second Pregnancy Trimester
Risk Management
Urinary Tract Infections
Vaccinium macrocarpon
Bacterial Adhesion
Anti-Bacterial Agents

Utility of Autopsy among Pediatric Allogeneic Hematopoietic Stem Cell Transplant Recipients: One Last Chance to Learn?

Kelly, M. S., Spees, L., Vinesett, R., Stokhuyzen, A., McGill, L., Proia, A. D., Jenkins, K., Arshad, M., Seed, P. C. & Martin, P. L., Sep 1 2018, In : Biology of Blood and Marrow Transplantation. 24, 9, p. 1861-1865 5 p.

Research output: Contribution to journalArticle

Hematopoietic Stem Cells
Autopsy
Pediatrics
Transplants
Transplant Recipients
2017
7 Citations (Scopus)
Enterostomy
Unsaturated Fatty Acids
Premature Infants
Small Intestine
Fats
4 Citations (Scopus)

HIV DNA-adenovirus multiclade envelope vaccine induces gp41 antibody immunodominance in rhesus macaques

Han, Q., Williams, W. B., Saunders, K. O., Seaton, K. E., Wiehe, K. J., Vandergrift, N., Von Holle, T. A., Trama, A. M., Parks, R. J., Luo, K., Gurley, T. C., Kepler, T. B., Marshall, D. J., Montefiori, D. C., Sutherland, L. L., Alam, M. S., Whitesides, J. F., Bowman, C. M., Permar, S. R., Graham, B. S. & 6 othersMascola, J. R., Seed, P. C., Van Rompay, K. K. A., Tomaras, G. D., Moody, M. A. & Haynes, B. F., Nov 1 2017, In : Journal of Virology. 91, 21, e00923-17.

Research output: Contribution to journalArticle

Adenoviridae
Macaca mulatta
Human immunodeficiency virus 1
Vaccines
HIV
6 Citations (Scopus)

Risk Factors Associated With Recurrent Urinary Tract Infection in Neurogenic Bladders Managed by Clean Intermittent Catheterization

Chaudhry, R., Balsara, Z. R., Madden-Fuentes, R. J., Wiener, J. S., Routh, J. C., Seed, P. & Ross, S. S., Apr 1 2017, In : Urology. 102, p. 213-218 6 p.

Research output: Contribution to journalArticle

Intermittent Urethral Catheterization
Neurogenic Urinary Bladder
Urinary Tract Infections
Spinal Dysraphism
Urodynamics
5 Citations (Scopus)

The Nasopharyngeal Microbiota of Children with Respiratory Infections in Botswana

Kelly, M. S., Surette, M. G., Smieja, M., Pernica, J. M., Rossi, L., Luinstra, K., Steenhoff, A. P., Feemster, K. A., Goldfarb, D. M., Arscott-Mills, T., Boiditswe, S., Rulaganyang, I., Muthoga, C., Gaofiwe, L., Mazhani, T., Rawls, J. F., Cunningham, C. K., Shah, S. S. & Seed, P. C., Sep 1 2017, In : Pediatric Infectious Disease Journal. 36, 9, p. e211-e218

Research output: Contribution to journalArticle

Botswana
Microbiota
Respiratory Tract Infections
Pneumonia
Odds Ratio
2016
6 Citations (Scopus)

Early-life intranasal colonization with nontypeable Haemophilus influenzae exacerbates juvenile airway disease in mice

McCann, J. R., Mason, S. N., Auten, R. L., St. Geme, J. W. & Seed, P. C., Jan 1 2016, In : Infection and immunity. 84, 7, p. 2022-2030 9 p.

Research output: Contribution to journalArticle

Haemophilus influenzae
Asthma
Ovalbumin
Hypersensitivity
Bronchoconstrictor Agents
7 Citations (Scopus)

Genetic and molecular basis of Kingella kingae encapsulation

Starr, K. F., Porsch, E. A., Seed, P. C. & Geme, J. W. S., Jun 1 2016, In : Infection and immunity. 84, 6, p. 1775-1784 10 p.

Research output: Contribution to journalArticle

Kingella kingae
Molecular Biology
Capsules
Genes
Glycosyltransferases
3 Citations (Scopus)

Inflammatory response of human gestational membranes to Ureaplasma parvum using a novel dual-chamber tissue explant system

Potts, L. C., Feng, L., Seed, P. C., Jayes, F. L., Kuchibhatla, M., Antczak, B., Nazzal, M. K. & Murtha, A. P., May 1 2016, In : Biology of Reproduction. 94, 5, 119.

Research output: Contribution to journalArticle

Ureaplasma
Amnion
Interleukin-8
Membranes
Matrix Metalloproteinase 2
8 Citations (Scopus)

Kingella kingae Expresses Four Structurally Distinct Polysaccharide Capsules That Differ in Their Correlation with Invasive Disease

Starr, K. F., Porsch, E. A., Seed, P. C., Heiss, C., Naran, R., Forsberg, L. S., Amit, U., Yagupsky, P., Azadi, P. & St. Geme, J. W., Oct 1 2016, In : PLoS Pathogens. 12, 10, e1005944.

Research output: Contribution to journalArticle

Kingella kingae
Capsules
Polysaccharides
Glycosyltransferases
Polymers
4 Citations (Scopus)

The role of progesterone and a novel progesterone receptor, progesterone receptor membrane component 1, in the inflammatory response of fetal membranes to ureaplasmaparvum infection

Feng, L., Ransom, C. E., Nazzal, M. K., Allen, T. K., Li, Y. J., Truong, T., Potts, L. C., Seed, P. C. & Murtha, A. P., Dec 1 2016, In : PLoS One. 11, 12, e0168102.

Research output: Contribution to journalArticle

Ureaplasma parvum
Extraembryonic Membranes
extraembryonic membranes
Ureaplasma
Progesterone Receptors
200 Citations (Scopus)

The severity of nonalcoholic fatty liver disease is associated with gut dysbiosis and shift in the metabolic function of the gut microbiota

Boursier, J., Mueller, O., Barret, M., Machado, M., Fizanne, L., Araujo-Perez, F., Guy, C. D., Seed, P. C., Rawls, J. F., David, L. A., Hunault, G., Oberti, F., Calès, P. & Diehl, A. M., Mar 1 2016, In : Hepatology. 63, 3, p. 764-775 12 p.

Research output: Contribution to journalArticle

Dysbiosis
Fibrosis
Ruminococcus
Bacteroides
Non-alcoholic Fatty Liver Disease
3 Citations (Scopus)

Threading the Needle: Small-Molecule Targeting of a Xenobiotic Receptor to Ablate Escherichia coli Polysaccharide Capsule Expression Without Altering Antibiotic Resistance

Arshad, M., Goller, C. C., Pilla, D., Schoenen, F. J. & Seed, P. C., Apr 15 2016, In : Journal of Infectious Diseases. 213, 8, p. 1330-1339 10 p.

Research output: Contribution to journalArticle

Uropathogenic Escherichia coli
Xenobiotics
Microbial Drug Resistance
Capsules
Needles
2015
3 Citations (Scopus)

Association between positive urine cultures and necrotizing enterocolitis in a large cohort of hospitalized infants

Pineda, L. C., Hornik, C. P., Seed, P. C., Cotten, C. M., Laughon, M. M., Bidegain, M., Clark, R. H. & Brian Smith, P., Oct 1 2015, In : Early Human Development. 91, 10, p. 583-586 4 p.

Research output: Contribution to journalArticle

Necrotizing Enterocolitis
Urine
Odds Ratio
Confidence Intervals
Gestational Age
8 Citations (Scopus)

Efficacy of Fluoroquinolone/Probiotic Combination Therapy for Recurrent Urinary Tract Infection in Children: A Retrospective Analysis

Madden-Fuentes, R. J., Arshad, M., Ross, S. S. & Seed, P. C., Sep 1 2015, In : Clinical Therapeutics. 37, 9, p. 2143-2147 5 p., 2628.

Research output: Contribution to journalArticle

Fluoroquinolones
Probiotics
Urinary Tract Infections
Watchful Waiting
Therapeutics
25 Citations (Scopus)

The human mycobiome

Seed, P. C., May 1 2015, In : Cold Spring Harbor Perspectives in Medicine. 5, 5, a019810.

Research output: Contribution to journalArticle

Microbiota
Physiology
Fungi
Health
Xenobiotics
2014
35 Citations (Scopus)

Bacteria localization and chorion thinning among preterm premature rupture of membranes

Fortner, K. B., Grotegut, C. A., Ransom, C. E., Bentley, R. C., Feng, L., Lan, L., Heine, R. P., Seed, P. C. & Murtha, A. P., Jan 8 2014, In : PloS one. 9, 1, e83338.

Research output: Contribution to journalArticle

Chorion
chorion
Bacteria
Membranes
bacteria
18 Citations (Scopus)

Inflammatory response to Escherichia coli urinary tract infection in the neurogenic bladder of the spinal cord injured host

Chaudhry, R., Madden-Fuentes, R. J., Ortiz, T. K., Balsara, Z., Tang, Y., Nseyo, U., Wiener, J. S., Ross, S. S. & Seed, P. C., Jan 1 2014, In : Journal of Urology. 191, 5, p. 1454-1461 8 p.

Research output: Contribution to journalArticle

Neurogenic Urinary Bladder
Urinary Tract Infections
Spinal Cord
Escherichia coli
Urinary Bladder
4 Citations (Scopus)

Lifting the mask: Identification of new small molecule inhibitors of uropathogenic Escherichia coli group 2 capsule biogenesis

Goller, C. C., Arshad, M., Noah, J. W., Ananthan, S., Evans, C. W., Nebane, N. M., Rasmussen, L., Sosa, M., Tower, N. A., White, E. L., Neuenswander, B., Porubsky, P., Maki, B. E., Rogers, S. A., Schoenen, F. & Seed, P. C., Jul 1 2014, In : PLoS One. 9, 7, e96054.

Research output: Contribution to journalArticle

uropathogenic Escherichia coli
Uropathogenic Escherichia coli
Masks
Escherichia coli
Capsules
2013
23 Citations (Scopus)

Enhanced susceptibility to urinary tract infection in the spinal cord-injured host with neurogenic bladder

Balsara, Z. R., Ross, S. S., Dolber, P. C., Wiener, J. S., Tang, Y. & Seed, P. C., Aug 1 2013, In : Infection and immunity. 81, 8, p. 3018-3026 9 p.

Research output: Contribution to journalArticle

Neurogenic Urinary Bladder
Urinary Tract Infections
Spinal Cord
Residual Volume
Urinary Bladder
6 Citations (Scopus)

The type 1 pili regulator gene fimX and pathogenicity island PAI-X as molecular markers of uropathogenic Escherichia coli

Bateman, S. L., Stapleton, A. E., Stamm, W. E., Hooton, T. M. & Seed, P. C., Aug 1 2013, In : Microbiology (United Kingdom). 159, 8, p. 1606-1617 12 p.

Research output: Contribution to journalArticle

Uropathogenic Escherichia coli
Genomic Islands
Regulator Genes
Urinary Tract
Genes
2012

Coming of age: Facile generation of attenuated vaccine strains through heterologous gene expression

Goller, C. C. & Seed, P. C., Jan 1 2012, In : Virulence. 3, 1, p. 12-14 3 p.

Research output: Contribution to journalArticle

Attenuated Vaccines
Gene Expression
Virulence Factors
Cellular Immunity
Virulence
14 Citations (Scopus)
Epigenomics
Macrophages
Nitrogen
Integration Host Factors
beta-Fructofuranosidase
12 Citations (Scopus)

How to Make It in the Urinary Tract: A Tutorial by Escherichia coli

Jorgensen, I. & Seed, P. C., Oct 1 2012, In : PLoS Pathogens. 8, 10, e1002907.

Research output: Contribution to journalArticle

Host-Pathogen Interactions
Escherichia coli Infections
Toll-Like Receptor 4
Urinary Tract
Urinary Tract Infections
2011
70 Citations (Scopus)

Beyond bacteria: A study of the enteric microbial consortium in extremely low birth weight infants

LaTuga, M. S., Ellis, J. C., Cotton, C. M., Goldberg, R. N., Wynn, J. L., Jackson, R. B. & Seed, P. C., Dec 8 2011, In : PLoS One. 6, 12, e27858.

Research output: Contribution to journalArticle

Microbial Consortia
Extremely Low Birth Weight Infant
low birth weight
Fungi
Bacteria
73 Citations (Scopus)

Population dynamics and niche distribution of uropathogenic Escherichia coli during acute and chronic urinary tract infection

Schwartz, D. J., Chen, S. L., Hultgren, S. J. & Seed, P. C., Oct 1 2011, In : Infection and immunity. 79, 10, p. 4250-4259 10 p.

Research output: Contribution to journalArticle

Uropathogenic Escherichia coli
Population Dynamics
Urinary Tract Infections
Cystitis
Bacteria
9 Citations (Scopus)
Uropathogenic Escherichia coli
DNA Polymerase beta
Genomic Instability
Urinary Tract Infections
Virulence
Uropathogenic Escherichia coli
DNA Polymerase beta
Genomic Instability
Urinary Tract Infections
Virulence
2010
1 Citation (Scopus)

Bartonella-related multifocal bone marrow enhancement without osteolysis

Connelly, S. V. & Seed, P. C., Dec 24 2010, In : Journal of Pediatric Infectious Diseases. 5, 3, p. 305-308 4 p.

Research output: Contribution to journalArticle

Bartonella henselae
Bartonella
Osteolysis
Bone Marrow
Fever
15 Citations (Scopus)

High-throughput identification of chemical inhibitors of E. coli group 2 capsule biogenesis as anti-virulence agents

Goller, C. C. & Seed, P. C., Jul 19 2010, In : PLoS One. 5, 7, e11642.

Research output: Contribution to journalArticle

chemical inhibitors
urinary tract diseases
Escherichia coli
Capsules
Virulence
27 Citations (Scopus)

Kingella kingae endocarditis and a cluster investigation among daycare attendees

Seña, A. C., Seed, P., Nicholson, B., Joyce, M. & Cunningham, C. K., Jan 1 2010, In : Pediatric Infectious Disease Journal. 29, 1, p. 86-88 3 p.

Research output: Contribution to journalArticle

Kingella kingae
Osteomyelitis
Endocarditis
Infectious Arthritis
Antibiotic Prophylaxis
72 Citations (Scopus)

Polysaccharide capsule and sialic acid-mediated regulation promote biofilm-like intracellular bacterial communities during cystitis

Anderson, G. G., Goller, C. C., Justice, S., Hultgren, S. J. & Seed, P. C., Mar 1 2010, In : Infection and Immunity. 78, 3, p. 963-975 13 p.

Research output: Contribution to journalArticle

Cystitis
N-Acetylneuraminic Acid
Biofilms
Capsules
Polysaccharides
11 Citations (Scopus)

Prevalence of renal anomalies after urinary tract infections in hospitalized infants less than 2 months of age

Nowell, L., Moran, C., Smith, P. B., Seed, P., Alexander, B. D., Cotten, C. M., Wiener, J. S. & Benjamin, D. K., Apr 1 2010, In : Journal of Perinatology. 30, 4, p. 281-285 5 p.

Research output: Contribution to journalArticle

Urinary Tract Infections
Neonatal Intensive Care Units
Kidney
Coagulase
Staphylococcus
38 Citations (Scopus)
Uropathogenic Escherichia coli
Virulence Factors
Biofilms
Urinary Tract Infections
Capsules
2009
240 Citations (Scopus)

Small-molecule inhibitors target Escherichia coli amyloid biogenesis and biofilm formation

Cegelski, L., Pinkner, J. S., Hammer, N. D., Cusumano, C. K., Hung, C. S., Chorell, E., Åberg, V., Walker, J. N., Seed, P. C., Almqvist, F., Chapman, M. R. & Hultgren, S. J., Jan 1 2009, In : Nature Chemical Biology. 5, 12, p. 913-919 7 p.

Research output: Contribution to journalArticle

Uropathogenic Escherichia coli
Biofilms
Amyloid
Escherichia coli
Urinary Tract Infections
2008
46 Citations (Scopus)

LeuX tRNA-dependent and -independent mechanisms of Escherichia coli pathogenesis in acute cystitis

Hannan, T. J., Mysorekar, I. U., Chen, S. L., Walker, J. N., Jones, J. M., Pinkner, J. S., Hultgren, S. J. & Seed, P. C., Jan 1 2008, In : Molecular Microbiology. 67, 1, p. 116-128 13 p.

Research output: Contribution to journalArticle

Genomic Islands
Cystitis
Transfer RNA
Uropathogenic Escherichia coli
Escherichia coli
2007
184 Citations (Scopus)

Development of intracellular bacterial communities of uropathogenic Escherichia coli depends on type 1 pili

Wright, K. J., Seed, P. C. & Hultgren, S. J., Sep 1 2007, In : Cellular Microbiology. 9, 9, p. 2230-2241 12 p.

Research output: Contribution to journalArticle

Uropathogenic Escherichia coli
Escherichia coli
Strain control
Bacteria
Biofilms
8 Citations (Scopus)

Polymerase chain reaction of tick-borne relapsing fever caused by Borrelia hermsii

Uhlmann, E. J., Seed, P. C., Schwan, T. G. & Storch, G. A., Mar 1 2007, In : Pediatric Infectious Disease Journal. 26, 3, p. 267-269 3 p.

Research output: Contribution to journalArticle

Ornithodoros
Borrelia
Relapsing Fever
Polymerase Chain Reaction
18 Citations (Scopus)

Predictive value of cerebrospinal fluid parameters in neonates with intraventricular drainage devices

Lenfestey, R. W., Smith, P. B., Moody, M. A., Clark, R. H., Cotten, C. M., Seed, P. C. & Benjamin, D. K., Sep 1 2007, In : Journal of neurosurgery. 107, 3 SUPPL., p. 209-212 4 p.

Research output: Contribution to journalArticle

Cerebrospinal Fluid
Ventriculoperitoneal Shunt
Drainage
Equipment and Supplies
Erythrocyte Count