Patrick Casey Seed

  • 3387 Citations
19952020

Research output per year

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Research Output

  • 3387 Citations
  • 61 Article
  • 6 Review article
  • 4 Comment/debate
  • 1 Short survey
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Article
1995

Activation of the Pseudomonas aeruginosa lasI gene by LasR and the Pseudomonas autoinducer PAI: An autoinduction regulatory hierarchy

Seed, P. C., Passador, L. & Iglewski, B. H., Jan 1 1995, In : Journal of Bacteriology. 177, 3, p. 654-659 6 p.

Research output: Contribution to journalArticle

203 Scopus citations
1997

Contribution of proteases and LasR to the virulence of Pseudomonas aeruginosa during corneal infections

Preston, M. J., Seed, P. C., Toder, D. S., Iglewski, B. H., Ohman, D. E., Gustin, J. K., Goldberg, J. B. & Pier, G. B., Aug 26 1997, In : Infection and Immunity. 65, 8, p. 3086-3090 5 p.

Research output: Contribution to journalArticle

130 Scopus citations

Regulation of las and rhl quorum sensing in Pseudomonas aeruginosa

Pesci, E. C., Pearson, J. P., Seed, P. C. & Iglewski, B. H., Jan 1 1997, In : Journal of Bacteriology. 179, 10, p. 3127-3132 6 p.

Research output: Contribution to journalArticle

587 Scopus citations
1999

RsaL, a novel repressor of virulence gene expression in Pseudomonas aeruginosa

De Kievit, T., Seed, P. C., Nezezon, J., Passador, L. & Iglewski, B. H., Apr 1999, In : Journal of bacteriology. 181, 7, p. 2175-2184 10 p.

Research output: Contribution to journalArticle

Open Access
118 Scopus citations
2005

Uropathogenic Escherichia coli flagella aid in efficient urinary tract colonization

Wright, K. J., Seed, P. C. & Hultgren, S. J., Nov 1 2005, In : Infection and immunity. 73, 11, p. 7657-7668 12 p.

Research output: Contribution to journalArticle

148 Scopus citations
2006

Filamentation by Escherichia coli subverts innate defenses during urinary tract infection

Justice, S. S., Hunstad, D. A., Seed, P. C. & Hultgren, S. J., Dec 26 2006, In : Proceedings of the National Academy of Sciences of the United States of America. 103, 52, p. 19884-19889 6 p.

Research output: Contribution to journalArticle

190 Scopus citations

Outbreak of Salmonella javiana infection at a children's hospital

Elward, A., Grim, A., Schroeder, P., Kieffer, P., Sellenriek, P., Ferrett, R., Adams, H. C., Phillips, V., Bartow, R., Mays, D., Lawrence, S., Seed, P., Holzmann-Pazgal, G., Polish, L., Leet, T. & Fraser, V., Jun 1 2006, In : Infection Control and Hospital Epidemiology. 27, 6, p. 586-592 7 p.

Research output: Contribution to journalArticle

11 Scopus citations

Rationally designed small compounds inhibit pilus biogenesis in uropathogenic bacteria

Pinkner, J. S., Remaut, H., Buelens, F., Miller, E., Åberg, V., Pemberton, N., Hedenström, M., Larsson, A., Seed, P., Waksman, G., Hultgren, S. J. & Almqvist, F., Nov 21 2006, In : Proceedings of the National Academy of Sciences of the United States of America. 103, 47, p. 17897-17902 6 p.

Research output: Contribution to journalArticle

213 Scopus citations
2007

Development of intracellular bacterial communities of uropathogenic Escherichia coli depends on type 1 pili

Wright, K. J., Seed, P. C. & Hultgren, S. J., Sep 1 2007, In : Cellular Microbiology. 9, 9, p. 2230-2241 12 p.

Research output: Contribution to journalArticle

195 Scopus citations

Polymerase chain reaction of tick-borne relapsing fever caused by Borrelia hermsii

Uhlmann, E. J., Seed, P. C., Schwan, T. G. & Storch, G. A., Mar 1 2007, In : Pediatric Infectious Disease Journal. 26, 3, p. 267-269 3 p.

Research output: Contribution to journalArticle

8 Scopus citations
2008

LeuX tRNA-dependent and -independent mechanisms of Escherichia coli pathogenesis in acute cystitis

Hannan, T. J., Mysorekar, I. U., Chen, S. L., Walker, J. N., Jones, J. M., Pinkner, J. S., Hultgren, S. J. & Seed, P. C., Jan 1 2008, In : Molecular Microbiology. 67, 1, p. 116-128 13 p.

Research output: Contribution to journalArticle

49 Scopus citations
2009

Small-molecule inhibitors target Escherichia coli amyloid biogenesis and biofilm formation

Cegelski, L., Pinkner, J. S., Hammer, N. D., Cusumano, C. K., Hung, C. S., Chorell, E., Åberg, V., Walker, J. N., Seed, P. C., Almqvist, F., Chapman, M. R. & Hultgren, S. J., Dec 2009, In : Nature Chemical Biology. 5, 12, p. 913-919 7 p.

Research output: Contribution to journalArticle

267 Scopus citations
2010

Bartonella-related multifocal bone marrow enhancement without osteolysis

Connelly, S. V. & Seed, P. C., Dec 24 2010, In : Journal of Pediatric Infectious Diseases. 5, 3, p. 305-308 4 p.

Research output: Contribution to journalArticle

1 Scopus citations

High-throughput identification of chemical inhibitors of E. coli group 2 capsule biogenesis as anti-virulence agents

Goller, C. C. & Seed, P. C., Jul 19 2010, In : PloS one. 5, 7, e11642.

Research output: Contribution to journalArticle

15 Scopus citations

Kingella kingae endocarditis and a cluster investigation among daycare attendees

Seña, A. C., Seed, P., Nicholson, B., Joyce, M. & Cunningham, C. K., Jan 2010, In : Pediatric Infectious Disease Journal. 29, 1, p. 86-88 3 p.

Research output: Contribution to journalArticle

27 Scopus citations

Polysaccharide capsule and sialic acid-mediated regulation promote biofilm-like intracellular bacterial communities during cystitis

Anderson, G. G., Goller, C. C., Justice, S., Hultgren, S. J. & Seed, P. C., Mar 1 2010, In : Infection and immunity. 78, 3, p. 963-975 13 p.

Research output: Contribution to journalArticle

75 Scopus citations

Prevalence of renal anomalies after urinary tract infections in hospitalized infants less than 2 months of age

Nowell, L., Moran, C., Smith, P. B., Seed, P., Alexander, B. D., Cotten, C. M., Wiener, J. S. & Benjamin, D. K., Apr 1 2010, In : Journal of Perinatology. 30, 4, p. 281-285 5 p.

Research output: Contribution to journalArticle

13 Scopus citations
41 Scopus citations
2011

Beyond bacteria: A study of the enteric microbial consortium in extremely low birth weight infants

LaTuga, M. S., Ellis, J. C., Cotton, C. M., Goldberg, R. N., Wynn, J. L., Jackson, R. B. & Seed, P. C., Dec 8 2011, In : PloS one. 6, 12, e27858.

Research output: Contribution to journalArticle

82 Scopus citations

Population dynamics and niche distribution of uropathogenic Escherichia coli during acute and chronic urinary tract infection

Schwartz, D. J., Chen, S. L., Hultgren, S. J. & Seed, P. C., Oct 1 2011, In : Infection and immunity. 79, 10, p. 4250-4259 10 p.

Research output: Contribution to journalArticle

80 Scopus citations
10 Scopus citations
2012

Coming of age: Facile generation of attenuated vaccine strains through heterologous gene expression

Goller, C. C. & Seed, P. C., Jan 1 2012, In : Virulence. 3, 1, p. 12-14 3 p.

Research output: Contribution to journalArticle

14 Scopus citations

How to Make It in the Urinary Tract: A Tutorial by Escherichia coli

Jorgensen, I. & Seed, P. C., Oct 1 2012, In : PLoS Pathogens. 8, 10, e1002907.

Research output: Contribution to journalArticle

14 Scopus citations
2013

Enhanced susceptibility to urinary tract infection in the spinal cord-injured host with neurogenic bladder

Balsara, Z. R., Ross, S. S., Dolber, P. C., Wiener, J. S., Tang, Y. & Seed, P. C., Aug 1 2013, In : Infection and immunity. 81, 8, p. 3018-3026 9 p.

Research output: Contribution to journalArticle

27 Scopus citations

The type 1 pili regulator gene fimX and pathogenicity island PAI-X as molecular markers of uropathogenic Escherichia coli

Bateman, S. L., Stapleton, A. E., Stamm, W. E., Hooton, T. M. & Seed, P. C., Aug 1 2013, In : Microbiology (United Kingdom). 159, 8, p. 1606-1617 12 p.

Research output: Contribution to journalArticle

6 Scopus citations
2014

Bacteria localization and chorion thinning among preterm premature rupture of membranes

Fortner, K. B., Grotegut, C. A., Ransom, C. E., Bentley, R. C., Feng, L., Lan, L., Heine, R. P., Seed, P. C. & Murtha, A. P., Jan 8 2014, In : PloS one. 9, 1, e83338.

Research output: Contribution to journalArticle

44 Scopus citations

Inflammatory response to Escherichia coli urinary tract infection in the neurogenic bladder of the spinal cord injured host

Chaudhry, R., Madden-Fuentes, R. J., Ortiz, T. K., Balsara, Z., Tang, Y., Nseyo, U., Wiener, J. S., Ross, S. S. & Seed, P. C., May 2014, In : Journal of Urology. 191, 5, p. 1454-1461 8 p.

Research output: Contribution to journalArticle

22 Scopus citations

Lifting the mask: Identification of new small molecule inhibitors of uropathogenic Escherichia coli group 2 capsule biogenesis

Goller, C. C., Arshad, M., Noah, J. W., Ananthan, S., Evans, C. W., Nebane, N. M., Rasmussen, L., Sosa, M., Tower, N. A., White, E. L., Neuenswander, B., Porubsky, P., Maki, B. E., Rogers, S. A., Schoenen, F. & Seed, P. C., Jul 1 2014, In : PloS one. 9, 7, e96054.

Research output: Contribution to journalArticle

4 Scopus citations
2015

Association between positive urine cultures and necrotizing enterocolitis in a large cohort of hospitalized infants

Pineda, L. C., Hornik, C. P., Seed, P. C., Cotten, C. M., Laughon, M. M., Bidegain, M., Clark, R. H. & Brian Smith, P., Oct 1 2015, In : Early Human Development. 91, 10, p. 583-586 4 p.

Research output: Contribution to journalArticle

3 Scopus citations

Efficacy of Fluoroquinolone/Probiotic Combination Therapy for Recurrent Urinary Tract Infection in Children: A Retrospective Analysis

Madden-Fuentes, R. J., Arshad, M., Ross, S. S. & Seed, P. C., Sep 1 2015, In : Clinical Therapeutics. 37, 9, p. 2143-2147 5 p., 2628.

Research output: Contribution to journalArticle

9 Scopus citations

The human mycobiome

Seed, P. C., May 1 2015, In : Cold Spring Harbor Perspectives in Medicine. 5, 5, a019810.

Research output: Contribution to journalArticle

40 Scopus citations
2016

Early-life intranasal colonization with nontypeable Haemophilus influenzae exacerbates juvenile airway disease in mice

McCann, J. R., Mason, S. N., Auten, R. L., St. Geme, J. W. & Seed, P. C., Jan 1 2016, In : Infection and immunity. 84, 7, p. 2022-2030 9 p.

Research output: Contribution to journalArticle

8 Scopus citations

Genetic and molecular basis of Kingella kingae encapsulation

Starr, K. F., Porsch, E. A., Seed, P. C. & Geme, J. W. S., Jun 1 2016, In : Infection and immunity. 84, 6, p. 1775-1784 10 p.

Research output: Contribution to journalArticle

9 Scopus citations

Inflammatory response of human gestational membranes to Ureaplasma parvum using a novel dual-chamber tissue explant system

Potts, L. C., Feng, L., Seed, P. C., Jayes, F. L., Kuchibhatla, M., Antczak, B., Nazzal, M. K. & Murtha, A. P., May 1 2016, In : Biology of Reproduction. 94, 5, 119.

Research output: Contribution to journalArticle

4 Scopus citations

Kingella kingae Expresses Four Structurally Distinct Polysaccharide Capsules That Differ in Their Correlation with Invasive Disease

Starr, K. F., Porsch, E. A., Seed, P. C., Heiss, C., Naran, R., Forsberg, L. S., Amit, U., Yagupsky, P., Azadi, P. & St. Geme, J. W., Oct 2016, In : PLoS pathogens. 12, 10, e1005944.

Research output: Contribution to journalArticle

9 Scopus citations

The role of progesterone and a novel progesterone receptor, progesterone receptor membrane component 1, in the inflammatory response of fetal membranes to ureaplasmaparvum infection

Feng, L., Ransom, C. E., Nazzal, M. K., Allen, T. K., Li, Y. J., Truong, T., Potts, L. C., Seed, P. C. & Murtha, A. P., Dec 2016, In : PloS one. 11, 12, e0168102.

Research output: Contribution to journalArticle

8 Scopus citations

The severity of nonalcoholic fatty liver disease is associated with gut dysbiosis and shift in the metabolic function of the gut microbiota

Boursier, J., Mueller, O., Barret, M., Machado, M., Fizanne, L., Araujo-Perez, F., Guy, C. D., Seed, P. C., Rawls, J. F., David, L. A., Hunault, G., Oberti, F., Calès, P. & Diehl, A. M., Mar 1 2016, In : Hepatology. 63, 3, p. 764-775 12 p.

Research output: Contribution to journalArticle

318 Scopus citations

Threading the Needle: Small-Molecule Targeting of a Xenobiotic Receptor to Ablate Escherichia coli Polysaccharide Capsule Expression Without Altering Antibiotic Resistance

Arshad, M., Goller, C. C., Pilla, D., Schoenen, F. J. & Seed, P. C., Apr 15 2016, In : Journal of Infectious Diseases. 213, 8, p. 1330-1339 10 p.

Research output: Contribution to journalArticle

5 Scopus citations
2017
12 Scopus citations

HIV DNA-adenovirus multiclade envelope vaccine induces gp41 antibody immunodominance in rhesus macaques

Han, Q., Williams, W. B., Saunders, K. O., Seaton, K. E., Wiehe, K. J., Vandergrift, N., Von Holle, T. A., Trama, A. M., Parks, R. J., Luo, K., Gurley, T. C., Kepler, T. B., Marshall, D. J., Montefiori, D. C., Sutherland, L. L., Alam, M. S., Whitesides, J. F., Bowman, C. M., Permar, S. R., Graham, B. S. & 6 others, Mascola, J. R., Seed, P. C., Van Rompay, K. K. A., Tomaras, G. D., Moody, M. A. & Haynes, B. F., Nov 1 2017, In : Journal of virology. 91, 21, e00923-17.

Research output: Contribution to journalArticle

5 Scopus citations

Risk Factors Associated With Recurrent Urinary Tract Infection in Neurogenic Bladders Managed by Clean Intermittent Catheterization

Chaudhry, R., Balsara, Z. R., Madden-Fuentes, R. J., Wiener, J. S., Routh, J. C., Seed, P. & Ross, S. S., Apr 2017, In : Urology. 102, p. 213-218 6 p.

Research output: Contribution to journalArticle

10 Scopus citations

The Nasopharyngeal Microbiota of Children with Respiratory Infections in Botswana

Kelly, M. S., Surette, M. G., Smieja, M., Pernica, J. M., Rossi, L., Luinstra, K., Steenhoff, A. P., Feemster, K. A., Goldfarb, D. M., Arscott-Mills, T., Boiditswe, S., Rulaganyang, I., Muthoga, C., Gaofiwe, L., Mazhani, T., Rawls, J. F., Cunningham, C. K., Shah, S. S. & Seed, P. C., Sep 1 2017, In : Pediatric Infectious Disease Journal. 36, 9, p. e211-e218

Research output: Contribution to journalArticle

11 Scopus citations
2018

Antimicrobial photodynamic therapy mediated by methylene blue and potassium iodide to treat urinary tract infection in a female rat model

Huang, Y. Y., Wintner, A., Seed, P. C., Brauns, T., Gelfand, J. A. & Hamblin, M. R., Dec 1 2018, In : Scientific reports. 8, 1, 7257.

Research output: Contribution to journalArticle

18 Scopus citations
2 Scopus citations

Copper Influences the Antibacterial Outcomes of a β-Lactamase-Activated Prochelator against Drug-Resistant Bacteria

Zaengle-Barone, J. M., Jackson, A. C., Besse, D. M., Becken, B., Arshad, M., Seed, P. C. & Franz, K. J., Jun 8 2018, In : ACS Infectious Diseases. 4, 6, p. 1019-1029 11 p.

Research output: Contribution to journalArticle

7 Scopus citations

Early-life skin microbiota in hospitalized preterm and full-term infants

Younge, N. E., Araújo-Pérez, F., Brandon, D. & Seed, P. C., May 31 2018, In : Microbiome. 6, 1, 1 p.

Research output: Contribution to journalArticle

9 Scopus citations

Pneumococcal Colonization and the Nasopharyngeal Microbiota of Children in Botswana

Kelly, M. S., Surette, M. G., Smieja, M., Rossi, L., Luinstra, K., Steenhoff, A. P., Goldfarb, D. M., Pernica, J. M., Arscott-Mills, T., Boiditswe, S., Mazhani, T., Rawls, J. F., Cunningham, C. K., Shah, S. S., Feemster, K. A. & Seed, P. C., Nov 1 2018, In : Pediatric Infectious Disease Journal. 37, 11, p. 1176-1183 8 p.

Research output: Contribution to journalArticle

Predominant bacteria and patterns of antibiotic susceptibility in urinary tract infection in children with spina bifida

Ortiz, T. K., Velazquez, N., Ding, L., Routh, J. C., Wiener, J. S., Seed, P. C. & Ross, S. S., Oct 2018, In : Journal of Pediatric Urology. 14, 5, p. 444.e1-444.e8

Research output: Contribution to journalArticle

4 Scopus citations