Patrick Casey Seed

  • 3058 Citations
1995 …2021
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Research Output 1995 2019

  • 3058 Citations
  • 60 Article
  • 6 Review article
  • 2 Comment/debate
  • 1 Short survey
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Article
194 Citations (Scopus)

Activation of the Pseudomonas aeruginosa lasI gene by LasR and the Pseudomonas autoinducer PAI: An autoinduction regulatory hierarchy

Seed, P. C., Passador, L. & Iglewski, B. H., Jan 1 1995, In : Journal of Bacteriology. 177, 3, p. 654-659 6 p.

Research output: Contribution to journalArticle

Pseudomonas
Pseudomonas aeruginosa
Escherichia coli
Genes
Aliivibrio fischeri
11 Citations (Scopus)

Antimicrobial photodynamic therapy mediated by methylene blue and potassium iodide to treat urinary tract infection in a female rat model

Huang, Y. Y., Wintner, A., Seed, P. C., Brauns, T., Gelfand, J. A. & Hamblin, M. R., Dec 1 2018, In : Scientific reports. 8, 1, 7257.

Research output: Contribution to journalArticle

Potassium Iodide
Methylene Blue
Photochemotherapy
Urinary Tract Infections
Uropathogenic Escherichia coli
3 Citations (Scopus)

Association between positive urine cultures and necrotizing enterocolitis in a large cohort of hospitalized infants

Pineda, L. C., Hornik, C. P., Seed, P. C., Cotten, C. M., Laughon, M. M., Bidegain, M., Clark, R. H. & Brian Smith, P., Oct 1 2015, In : Early Human Development. 91, 10, p. 583-586 4 p.

Research output: Contribution to journalArticle

Necrotizing Enterocolitis
Urine
Odds Ratio
Confidence Intervals
Gestational Age
35 Citations (Scopus)

Bacteria localization and chorion thinning among preterm premature rupture of membranes

Fortner, K. B., Grotegut, C. A., Ransom, C. E., Bentley, R. C., Feng, L., Lan, L., Heine, R. P., Seed, P. C. & Murtha, A. P., Jan 8 2014, In : PloS one. 9, 1, e83338.

Research output: Contribution to journalArticle

Chorion
chorion
Bacteria
Membranes
bacteria
1 Citation (Scopus)

Bartonella-related multifocal bone marrow enhancement without osteolysis

Connelly, S. V. & Seed, P. C., Dec 24 2010, In : Journal of Pediatric Infectious Diseases. 5, 3, p. 305-308 4 p.

Research output: Contribution to journalArticle

Bartonella henselae
Bartonella
Osteolysis
Bone Marrow
Fever
75 Citations (Scopus)

Beyond bacteria: A study of the enteric microbial consortium in extremely low birth weight infants

LaTuga, M. S., Ellis, J. C., Cotton, C. M., Goldberg, R. N., Wynn, J. L., Jackson, R. B. & Seed, P. C., Dec 8 2011, In : PLoS One. 6, 12, e27858.

Research output: Contribution to journalArticle

Microbial Consortia
Extremely Low Birth Weight Infant
low birth weight
Fungi
Bacteria
Glycogen Storage Disease Type II
Clostridium difficile
Clostridium Infections
Morbidity
Metronidazole

Coming of age: Facile generation of attenuated vaccine strains through heterologous gene expression

Goller, C. C. & Seed, P. C., Jan 1 2012, In : Virulence. 3, 1, p. 12-14 3 p.

Research output: Contribution to journalArticle

Attenuated Vaccines
Gene Expression
Virulence Factors
Cellular Immunity
Virulence
128 Citations (Scopus)

Contribution of proteases and LasR to the virulence of Pseudomonas aeruginosa during corneal infections

Preston, M. J., Seed, P. C., Toder, D. S., Iglewski, B. H., Ohman, D. E., Gustin, J. K., Goldberg, J. B. & Pier, G. B., Aug 26 1997, In : Infection and Immunity. 65, 8, p. 3086-3090 5 p.

Research output: Contribution to journalArticle

Pseudomonas aeruginosa
Virulence
Peptide Hydrolases
Cornea
Infection
4 Citations (Scopus)

Copper Influences the Antibacterial Outcomes of a β-Lactamase-Activated Prochelator against Drug-Resistant Bacteria

Zaengle-Barone, J. M., Jackson, A. C., Besse, D. M., Becken, B., Arshad, M., Seed, P. C. & Franz, K. J., Jun 8 2018, In : ACS Infectious Diseases. 4, 6, p. 1019-1029 11 p.

Research output: Contribution to journalArticle

Copper
Bacteria
Pharmaceutical Preparations
Metals
Anti-Bacterial Agents
1 Citation (Scopus)

Detection of respiratory pathogens in clinical samples using metagenomic shotgun sequencing

Qi, C., Hountras, P., Pickens, C. O., Walter, J. M., Kruser, J. M., Singer, B., Seed, P. C., Green, S. J. & Wunderink, R. G., Jul 1 2019, In : Journal of Medical Microbiology. 68, 7, p. 996-1002 7 p.

Research output: Contribution to journalArticle

Metagenome
Metagenomics
Firearms
Bronchoalveolar Lavage
Pneumonia
189 Citations (Scopus)

Development of intracellular bacterial communities of uropathogenic Escherichia coli depends on type 1 pili

Wright, K. J., Seed, P. C. & Hultgren, S. J., Sep 1 2007, In : Cellular Microbiology. 9, 9, p. 2230-2241 12 p.

Research output: Contribution to journalArticle

Uropathogenic Escherichia coli
Escherichia coli
Strain control
Bacteria
Biofilms

Disrupted Maturation of the Microbiota and Metabolome among Extremely Preterm Infants with Postnatal Growth Failure

Younge, N. E., Newgard, C. B., Cotten, C. M., Goldberg, R. N., Muehlbauer, M. J., Bain, J. R., Stevens, R. D., O’Connell, T. M., Rawls, J. F., Seed, P. C. & Ashley, P. L., Dec 1 2019, In : Scientific reports. 9, 1, 8167.

Research output: Contribution to journalArticle

Open Access
Extremely Premature Infants
Metabolome
Microbiota
Growth
Premature Infants
8 Citations (Scopus)

Early-life intranasal colonization with nontypeable Haemophilus influenzae exacerbates juvenile airway disease in mice

McCann, J. R., Mason, S. N., Auten, R. L., St. Geme, J. W. & Seed, P. C., Jan 1 2016, In : Infection and immunity. 84, 7, p. 2022-2030 9 p.

Research output: Contribution to journalArticle

Haemophilus influenzae
Asthma
Ovalbumin
Hypersensitivity
Bronchoconstrictor Agents
4 Citations (Scopus)

Early-life skin microbiota in hospitalized preterm and full-term infants

Younge, N. E., Araújo-Pérez, F., Brandon, D. & Seed, P. C., May 31 2018, In : Microbiome. 6, 1, 1 p.

Research output: Contribution to journalArticle

Microbiota
Skin
Escherichia
Staphylococcus
Enterobacter
8 Citations (Scopus)

Efficacy of Fluoroquinolone/Probiotic Combination Therapy for Recurrent Urinary Tract Infection in Children: A Retrospective Analysis

Madden-Fuentes, R. J., Arshad, M., Ross, S. S. & Seed, P. C., Sep 1 2015, In : Clinical Therapeutics. 37, 9, p. 2143-2147 5 p., 2628.

Research output: Contribution to journalArticle

Fluoroquinolones
Probiotics
Urinary Tract Infections
Watchful Waiting
Therapeutics
24 Citations (Scopus)

Enhanced susceptibility to urinary tract infection in the spinal cord-injured host with neurogenic bladder

Balsara, Z. R., Ross, S. S., Dolber, P. C., Wiener, J. S., Tang, Y. & Seed, P. C., Aug 1 2013, In : Infection and immunity. 81, 8, p. 3018-3026 9 p.

Research output: Contribution to journalArticle

Neurogenic Urinary Bladder
Urinary Tract Infections
Spinal Cord
Residual Volume
Urinary Bladder
8 Citations (Scopus)
Enterostomy
Unsaturated Fatty Acids
Premature Infants
Small Intestine
Fats
14 Citations (Scopus)
Epigenomics
Macrophages
Nitrogen
Integration Host Factors
beta-Fructofuranosidase
1 Citation (Scopus)

Fetal exposure to the maternal microbiota in humans and mice

Younge, N., McCann, J. R., Ballard, J., Plunkett, C., Akhtar, S., Araújo-Pérez, F., Murtha, A., Brandon, D. & Seed, P. C., Jan 1 2019, In : JCI Insight. 4, 19, e127806.

Research output: Contribution to journalArticle

Maternal Exposure
Microbiota
Microbial Viability
Pregnancy
Bacteria
183 Citations (Scopus)

Filamentation by Escherichia coli subverts innate defenses during urinary tract infection

Justice, S. S., Hunstad, D. A., Seed, P. C. & Hultgren, S. J., Dec 26 2006, In : Proceedings of the National Academy of Sciences of the United States of America. 103, 52, p. 19884-19889 6 p.

Research output: Contribution to journalArticle

Uropathogenic Escherichia coli
Urinary Tract Infections
Escherichia coli
Cystitis
Innate Immunity
7 Citations (Scopus)

Genetic and molecular basis of Kingella kingae encapsulation

Starr, K. F., Porsch, E. A., Seed, P. C. & Geme, J. W. S., Jun 1 2016, In : Infection and immunity. 84, 6, p. 1775-1784 10 p.

Research output: Contribution to journalArticle

Kingella kingae
Molecular Biology
Capsules
Genes
Glycosyltransferases

Gut Colonization Preceding Mucosal Barrier Injury Bloodstream Infection in Pediatric Hematopoietic Stem Cell Transplantation Recipients

Kelly, M. S., Ward, D. V., Severyn, C. J., Arshad, M., Heston, S. M., Jenkins, K., Martin, P. L., McGill, L., Stokhuyzen, A., Bhattarai, S. K., Bucci, V. & Seed, P. C., Jan 1 2019, In : Biology of Blood and Marrow Transplantation.

Research output: Contribution to journalArticle

Hematopoietic Stem Cell Transplantation
Pediatrics
Wounds and Injuries
Infection
Cloaca
15 Citations (Scopus)

High-throughput identification of chemical inhibitors of E. coli group 2 capsule biogenesis as anti-virulence agents

Goller, C. C. & Seed, P. C., Jul 19 2010, In : PLoS One. 5, 7, e11642.

Research output: Contribution to journalArticle

chemical inhibitors
urinary tract diseases
Escherichia coli
Capsules
Virulence
4 Citations (Scopus)

HIV DNA-adenovirus multiclade envelope vaccine induces gp41 antibody immunodominance in rhesus macaques

Han, Q., Williams, W. B., Saunders, K. O., Seaton, K. E., Wiehe, K. J., Vandergrift, N., Von Holle, T. A., Trama, A. M., Parks, R. J., Luo, K., Gurley, T. C., Kepler, T. B., Marshall, D. J., Montefiori, D. C., Sutherland, L. L., Alam, M. S., Whitesides, J. F., Bowman, C. M., Permar, S. R., Graham, B. S. & 6 others, Mascola, J. R., Seed, P. C., Van Rompay, K. K. A., Tomaras, G. D., Moody, M. A. & Haynes, B. F., Nov 1 2017, In : Journal of virology. 91, 21, e00923-17.

Research output: Contribution to journalArticle

Adenoviridae
Macaca mulatta
Human immunodeficiency virus 1
Vaccines
HIV
13 Citations (Scopus)

How to Make It in the Urinary Tract: A Tutorial by Escherichia coli

Jorgensen, I. & Seed, P. C., Oct 1 2012, In : PLoS Pathogens. 8, 10, e1002907.

Research output: Contribution to journalArticle

Host-Pathogen Interactions
Escherichia coli Infections
Toll-Like Receptor 4
Urinary Tract
Urinary Tract Infections
4 Citations (Scopus)

Inflammatory response of human gestational membranes to Ureaplasma parvum using a novel dual-chamber tissue explant system

Potts, L. C., Feng, L., Seed, P. C., Jayes, F. L., Kuchibhatla, M., Antczak, B., Nazzal, M. K. & Murtha, A. P., May 1 2016, In : Biology of Reproduction. 94, 5, 119.

Research output: Contribution to journalArticle

Ureaplasma
Amnion
Interleukin-8
Membranes
Matrix Metalloproteinase 2
20 Citations (Scopus)

Inflammatory response to Escherichia coli urinary tract infection in the neurogenic bladder of the spinal cord injured host

Chaudhry, R., Madden-Fuentes, R. J., Ortiz, T. K., Balsara, Z., Tang, Y., Nseyo, U., Wiener, J. S., Ross, S. S. & Seed, P. C., Jan 1 2014, In : Journal of Urology. 191, 5, p. 1454-1461 8 p.

Research output: Contribution to journalArticle

Neurogenic Urinary Bladder
Urinary Tract Infections
Spinal Cord
Escherichia coli
Urinary Bladder
27 Citations (Scopus)

Kingella kingae endocarditis and a cluster investigation among daycare attendees

Seña, A. C., Seed, P., Nicholson, B., Joyce, M. & Cunningham, C. K., Jan 1 2010, In : Pediatric Infectious Disease Journal. 29, 1, p. 86-88 3 p.

Research output: Contribution to journalArticle

Kingella kingae
Osteomyelitis
Endocarditis
Infectious Arthritis
Antibiotic Prophylaxis
8 Citations (Scopus)

Kingella kingae Expresses Four Structurally Distinct Polysaccharide Capsules That Differ in Their Correlation with Invasive Disease

Starr, K. F., Porsch, E. A., Seed, P. C., Heiss, C., Naran, R., Forsberg, L. S., Amit, U., Yagupsky, P., Azadi, P. & St. Geme, J. W., Oct 1 2016, In : PLoS pathogens. 12, 10, e1005944.

Research output: Contribution to journalArticle

Kingella kingae
Capsules
Polysaccharides
Glycosyltransferases
Polymers
48 Citations (Scopus)

LeuX tRNA-dependent and -independent mechanisms of Escherichia coli pathogenesis in acute cystitis

Hannan, T. J., Mysorekar, I. U., Chen, S. L., Walker, J. N., Jones, J. M., Pinkner, J. S., Hultgren, S. J. & Seed, P. C., Jan 1 2008, In : Molecular Microbiology. 67, 1, p. 116-128 13 p.

Research output: Contribution to journalArticle

Genomic Islands
Cystitis
Transfer RNA
Uropathogenic Escherichia coli
Escherichia coli
4 Citations (Scopus)

Lifting the mask: Identification of new small molecule inhibitors of uropathogenic Escherichia coli group 2 capsule biogenesis

Goller, C. C., Arshad, M., Noah, J. W., Ananthan, S., Evans, C. W., Nebane, N. M., Rasmussen, L., Sosa, M., Tower, N. A., White, E. L., Neuenswander, B., Porubsky, P., Maki, B. E., Rogers, S. A., Schoenen, F. & Seed, P. C., Jul 1 2014, In : PLoS One. 9, 7, e96054.

Research output: Contribution to journalArticle

uropathogenic Escherichia coli
Uropathogenic Escherichia coli
Masks
Escherichia coli
Capsules
11 Citations (Scopus)

Outbreak of Salmonella javiana infection at a children's hospital

Elward, A., Grim, A., Schroeder, P., Kieffer, P., Sellenriek, P., Ferrett, R., Adams, H. C., Phillips, V., Bartow, R., Mays, D., Lawrence, S., Seed, P., Holzmann-Pazgal, G., Polish, L., Leet, T. & Fraser, V., Jun 1 2006, In : Infection Control and Hospital Epidemiology. 27, 6, p. 586-592 7 p.

Research output: Contribution to journalArticle

Salmonella Infections
Disease Outbreaks
Gastroenteritis
Odds Ratio
Confidence Intervals

Pneumococcal Colonization and the Nasopharyngeal Microbiota of Children in Botswana

Kelly, M. S., Surette, M. G., Smieja, M., Rossi, L., Luinstra, K., Steenhoff, A. P., Goldfarb, D. M., Pernica, J. M., Arscott-Mills, T., Boiditswe, S., Mazhani, T., Rawls, J. F., Cunningham, C. K., Shah, S. S., Feemster, K. A. & Seed, P. C., Nov 1 2018, In : The Pediatric infectious disease journal. 37, 11, p. 1176-1183 8 p.

Research output: Contribution to journalArticle

Botswana
Microbiota
Streptococcus pneumoniae
Pneumococcal Infections
Moraxella
8 Citations (Scopus)

Polymerase chain reaction of tick-borne relapsing fever caused by Borrelia hermsii

Uhlmann, E. J., Seed, P. C., Schwan, T. G. & Storch, G. A., Mar 1 2007, In : Pediatric Infectious Disease Journal. 26, 3, p. 267-269 3 p.

Research output: Contribution to journalArticle

Ornithodoros
Borrelia
Relapsing Fever
Polymerase Chain Reaction
74 Citations (Scopus)

Polysaccharide capsule and sialic acid-mediated regulation promote biofilm-like intracellular bacterial communities during cystitis

Anderson, G. G., Goller, C. C., Justice, S., Hultgren, S. J. & Seed, P. C., Mar 1 2010, In : Infection and immunity. 78, 3, p. 963-975 13 p.

Research output: Contribution to journalArticle

Cystitis
N-Acetylneuraminic Acid
Biofilms
Capsules
Polysaccharides
77 Citations (Scopus)

Population dynamics and niche distribution of uropathogenic Escherichia coli during acute and chronic urinary tract infection

Schwartz, D. J., Chen, S. L., Hultgren, S. J. & Seed, P. C., Oct 1 2011, In : Infection and immunity. 79, 10, p. 4250-4259 10 p.

Research output: Contribution to journalArticle

Uropathogenic Escherichia coli
Population Dynamics
Urinary Tract Infections
Cystitis
Bacteria
18 Citations (Scopus)

Predictive value of cerebrospinal fluid parameters in neonates with intraventricular drainage devices

Lenfestey, R. W., Smith, P. B., Moody, M. A., Clark, R. H., Cotten, C. M., Seed, P. C. & Benjamin, D. K., Sep 1 2007, In : Journal of neurosurgery. 107, 3 SUPPL., p. 209-212 4 p.

Research output: Contribution to journalArticle

Cerebrospinal Fluid
Ventriculoperitoneal Shunt
Drainage
Equipment and Supplies
Erythrocyte Count
2 Citations (Scopus)

Predominant bacteria and patterns of antibiotic susceptibility in urinary tract infection in children with spina bifida

Ortiz, T. K., Velazquez, N., Ding, L., Routh, J. C., Wiener, J. S., Seed, P. C. & Ross, S. S., Oct 1 2018, In : Journal of Pediatric Urology. 14, 5, p. 444.e1-444.e8

Research output: Contribution to journalArticle

Spinal Dysraphism
Urinary Tract Infections
Anti-Bacterial Agents
Bacteria
Pediatrics
11 Citations (Scopus)

Prevalence of renal anomalies after urinary tract infections in hospitalized infants less than 2 months of age

Nowell, L., Moran, C., Smith, P. B., Seed, P., Alexander, B. D., Cotten, C. M., Wiener, J. S. & Benjamin, D. K., Apr 1 2010, In : Journal of Perinatology. 30, 4, p. 281-285 5 p.

Research output: Contribution to journalArticle

Urinary Tract Infections
Neonatal Intensive Care Units
Kidney
Coagulase
Staphylococcus
207 Citations (Scopus)

Rationally designed small compounds inhibit pilus biogenesis in uropathogenic bacteria

Pinkner, J. S., Remaut, H., Buelens, F., Miller, E., Åberg, V., Pemberton, N., Hedenström, M., Larsson, A., Seed, P., Waksman, G., Hultgren, S. J. & Almqvist, F., Nov 21 2006, In : Proceedings of the National Academy of Sciences of the United States of America. 103, 47, p. 17897-17902 6 p.

Research output: Contribution to journalArticle

Virulence Factors
Uropathogenic Escherichia coli
Bacteria
Surface Plasmon Resonance
Hemagglutination
1 Citation (Scopus)

Reduction in Mortality after Umbilical Cord Blood Transplantation in Children Over a 20-Year Period (1995-2014)

Spees, L. P., Martin, P. L., Kurtzberg, J., Stokhuyzen, A., McGill, L., Prasad, V. K., Driscoll, T. A., Parikh, S. H., Page, K. M., Vinesett, R., Severyn, C., Sung, A. D., Proia, A. D., Jenkins, K., Arshad, M., Steinbach, W. J., Seed, P. C. & Kelly, M. S., Apr 1 2019, In : Biology of Blood and Marrow Transplantation. 25, 4, p. 756-763 8 p.

Research output: Contribution to journalArticle

Fetal Blood
Transplantation
Mortality
Aspergillosis
Graft vs Host Disease
565 Citations (Scopus)

Regulation of las and rhl quorum sensing in Pseudomonas aeruginosa

Pesci, E. C., Pearson, J. P., Seed, P. C. & Iglewski, B. H., Jan 1 1997, In : Journal of Bacteriology. 179, 10, p. 3127-3132 6 p.

Research output: Contribution to journalArticle

Quorum Sensing
Pseudomonas aeruginosa
Plasminogen Activator Inhibitor 2
Plasminogen Activator Inhibitor 1
Lac Operon
38 Citations (Scopus)
Uropathogenic Escherichia coli
Virulence Factors
Biofilms
Urinary Tract Infections
Capsules
7 Citations (Scopus)

Risk Factors Associated With Recurrent Urinary Tract Infection in Neurogenic Bladders Managed by Clean Intermittent Catheterization

Chaudhry, R., Balsara, Z. R., Madden-Fuentes, R. J., Wiener, J. S., Routh, J. C., Seed, P. & Ross, S. S., Apr 1 2017, In : Urology. 102, p. 213-218 6 p.

Research output: Contribution to journalArticle

Intermittent Urethral Catheterization
Neurogenic Urinary Bladder
Urinary Tract Infections
Spinal Dysraphism
Urodynamics
114 Citations (Scopus)

RsaL, a novel repressor of virulence gene expression in Pseudomonas aeruginosa

De Kievit, T., Seed, P. C., Nezezon, J., Passador, L. & Iglewski, B. H., Apr 1 1999, In : Journal of Bacteriology. 181, 7, p. 2175-2184 10 p.

Research output: Contribution to journalArticle

Pseudomonas aeruginosa
Plasminogen Activator Inhibitor 1
Virulence
Quorum Sensing
Gene Expression
250 Citations (Scopus)

Small-molecule inhibitors target Escherichia coli amyloid biogenesis and biofilm formation

Cegelski, L., Pinkner, J. S., Hammer, N. D., Cusumano, C. K., Hung, C. S., Chorell, E., Åberg, V., Walker, J. N., Seed, P. C., Almqvist, F., Chapman, M. R. & Hultgren, S. J., Jan 1 2009, In : Nature Chemical Biology. 5, 12, p. 913-919 7 p.

Research output: Contribution to journalArticle

Uropathogenic Escherichia coli
Biofilms
Amyloid
Escherichia coli
Urinary Tract Infections
29 Citations (Scopus)

The human mycobiome

Seed, P. C., May 1 2015, In : Cold Spring Harbor Perspectives in Medicine. 5, 5, a019810.

Research output: Contribution to journalArticle

Microbiota
Physiology
Fungi
Health
Xenobiotics
13 Citations (Scopus)

The microbiome in patients with atopic dermatitis

Paller, A., Kong, H. H., Seed, P. C., Naik, S., Scharschmidt, T. C., Gallo, R. L., Luger, T. & Irvine, A. D., Jan 1 2019, In : Journal of Allergy and Clinical Immunology. 143, 1, p. 26-35 10 p.

Research output: Contribution to journalArticle

Microbiota
Atopic Dermatitis
Skin
Methylobacteriaceae
Immune System
5 Citations (Scopus)

The Nasopharyngeal Microbiota of Children with Respiratory Infections in Botswana

Kelly, M. S., Surette, M. G., Smieja, M., Pernica, J. M., Rossi, L., Luinstra, K., Steenhoff, A. P., Feemster, K. A., Goldfarb, D. M., Arscott-Mills, T., Boiditswe, S., Rulaganyang, I., Muthoga, C., Gaofiwe, L., Mazhani, T., Rawls, J. F., Cunningham, C. K., Shah, S. S. & Seed, P. C., Sep 1 2017, In : Pediatric Infectious Disease Journal. 36, 9, p. e211-e218

Research output: Contribution to journalArticle

Botswana
Microbiota
Respiratory Tract Infections
Pneumonia
Odds Ratio