• 2792 Citations
1990 …2021
If you made any changes in Pure, your changes will be visible here soon.

Personal profile

Research Interests

The primary focus of the Kiser research group is developing and translating new drug delivery technologies for the prevention and treatment of HIV infection. We are particularly interested in new antiviral agents and drug delivery systems to intercept sexually transmitted viruses at the point of interaction with the genital mucosa and the first target cells infected in the mucosa. Our methods include synthetic polymer chemistry, pharmaceutical chemistry, modeling drug transport, and using these results in drug delivery system design and prototyping. We perform preclinical toxicity efficacy evaluations in cell, tissue, and animal models; conduct antiviral assays and drug transport assays; and produce devices using a variety of pharmaceutical manufacturing technologies. Our projects range from new materials discovery that could lead to next generation mucosally active antiviral agents and mucosal vaccines, to the development of new assays to evaluate HIV prevention technologies, to sustained delivery system projects for antiviral, anti-infectives and contraceptive agents. The lab is funded by the NIH (NIAD), the Bill and Melinda Gates Foundation and USAID.

Education/Academic qualification

Mechanical Engineering and Materials Science, PhD, Duke University

… → 1999

MS, University of Wisconsin-Milwaukee

… → 1989

Chemistry and Philosophy, BS, University of Wisconsin-Madison

Fingerprint Dive into the research topics where Patrick Kiser is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 7 Similar Profiles
Tenofovir Medicine & Life Sciences
Anti-Infective Agents Medicine & Life Sciences
HIV Medicine & Life Sciences
HIV-1 Medicine & Life Sciences
Polyurethanes Medicine & Life Sciences
Foams and Jellies Vaginal Creams Medicine & Life Sciences
Hydrogels Engineering & Materials Science
Gels Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Grants 2011 2021

Drug delivery
Prodrugs
Substrates
Technical presentations
Mass spectrometry
HIV Infections
HIV
Drug Implants
Technology Transfer
Levonorgestrel
Drug Delivery Systems
HIV
Pharmaceutical Preparations
Investigational New Drug Application
Pharmacokinetics
Drug Delivery Systems
HIV
Pharmaceutical Preparations
Investigational New Drug Application
Pharmacokinetics

Research Output 1990 2018

Qualitative consumer research on acceptance of long-acting pre-exposure prophylaxis products among men having sex with men and medical practitioners in the United States

Calder, B., Schieffer, R. J., Bryndza Tfaily, E., D'Aquila, R. T., Greene, G. J., Carballo-Diéguez, A., Giguere, R., Kiser, P. & Hope, T. J., Oct 1 2018, In : AIDS research and human retroviruses. 34, 10, p. 849-856 8 p.

Research output: Contribution to journalArticle

Qualitative Research
San Francisco
Marketing
Focus Groups
Research
6 Citations (Scopus)

Randomized, placebo controlled phase I trial of safety, pharmacokinetics, pharmacodynamics and acceptability of tenofovir and tenofovir plus levonorgestrel vaginal rings in women

Thurman, A. R., Schwartz, J. L., Brache, V., Clark, M. R., McCormick, T., Chandra, N., Marzinke, M. A., Stanczyk, F. Z., Dezzutti, C. S., Hillier, S. L., Herold, B. C., Fichorova, R., Asin, S. N., Rollenhagen, C., Weiner, D., Kiser, P. & Doncel, G. F., Jun 1 2018, In : PloS one. 13, 6, e0199778.

Research output: Contribution to journalArticle

Tenofovir
Female Contraceptive Devices
Pharmacodynamics
cervical mucus
Levonorgestrel
1 Citation (Scopus)

A Dose Ranging Pharmacokinetic Evaluation of IQP-0528 Released from Intravaginal Rings in Non-Human Primates

Su, J. T., Teller, R. S., Srinivasan, P., Zhang, J., Martin, A., Sung, S., Smith, J. M. & Kiser, P., Oct 1 2017, In : Pharmaceutical Research. 34, 10, p. 2163-2171 9 p.

Research output: Contribution to journalArticle

Pharmacokinetics
Primates
Pharmaceutical Preparations
Macaca nemestrina
IQP-0528
2 Citations (Scopus)

Long-term direct visualization of passively transferred fluorophore-conjugated antibodies

Schneider, J. R., Carias, A. M., Bastian, A. R., Cianci, G. C., Kiser, P., Veazey, R. S. & Hope, T. J., Nov 1 2017, In : Journal of Immunological Methods. 450, p. 66-72 7 p.

Research output: Contribution to journalArticle

Antibodies
Intravenous Immunoglobulins
Macaca
Mucous Membrane
Biopsy
35 Citations (Scopus)

Preferences for Long-Acting Pre-exposure Prophylaxis (PrEP), Daily Oral PrEP, or Condoms for HIV Prevention Among U.S. Men Who Have Sex with Men

Greene, G. J., Swann, G., Fought, A. J., Carballo-Diéguez, A., Hope, T. J., Kiser, P., Mustanski, B. & D'Aquila, R. T., May 1 2017, In : AIDS and behavior. 21, 5, p. 1336-1349 14 p.

Research output: Contribution to journalArticle

Condoms
HIV
Privacy
Injections
Pre-Exposure Prophylaxis