Grants per year
Personal profile
Research Interests
We use human induced pluripotent stem cells (hiPSCs) to understand the role of the genome in influencing drug efficacy and side effects as well as complex disease traits. We are also interested in pluripotency, differentiation methods, cardiac regenerative medicine, direct reprogramming, long QT syndrome, atrial fibrillation, peripheral artery disease, and hiPSC models of cancer. Along with the hiPSC model, we use a combination of whole genome sequencing, automation and robotics, high-throughput drug screening, high-content imaging, and electrophysiological testing.
Expertise related to UN Sustainable Devlopment Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Stem Cell Biology, PhD, University of Nottingham
… → 2008
Research interests
- Adverse Drug Reactions
- Bioengineering
- Bioinformatics
- Breast Cancer
- Cardiology
- Drug Discovery
- Regenerative Medicine
- Stem Cells
- Alzheimer's Disease
- Arrhythmias
- Atherosclerosis
- Cardiovascular Diseases
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Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Kinetic Imaging Plate Reader for Drug Discovery and Biology
George Jr., A. L., Arispe, L., Bass, J., Burridge, P., DeCaen, P. G., Gianneschi, N., Horvath, C. M., Kiskinis, E., Klein, W. L., Miller, R. J., Morimoto, R. I., Moskal, J. R., Penzes, P., Prakriya, M., Scheidt, K. A., Surmeier Jr, D. J. & Vafabakhsh, R.
Office of the Director, National Institutes of Health
9/1/21 → 8/31/22
Project: Research project
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Predicting and Preventing Chemotherapy-Induced Cardiotoxicity in African American Children
8/5/21 → 7/31/26
Project: Research project
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Unravelling the Role of Genome in Pediatric Long QT Syndrome variable expressivity
Burridge, P., George Jr., A. L., Roy-Puckelwartz, M. J., Stranger, B. E. & Webster, G.
7/1/21 → 6/30/24
Project: Research project
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Research Output
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An updated protocol for the cost-effective and weekend-free culture of human induced pluripotent stem cells
Lyra-Leite, D. M., Fonoudi, H., Gharib, M. & Burridge, P. W., Mar 19 2021, In: STAR Protocols. 2, 1, 100213.Research output: Contribution to journal › Article › peer-review
Open Access -
Cellular model systems to study cardiovascular injury from chemotherapy
Fonoudi, H. & Burridge, P. W., May 2021, In: Journal of thrombosis and thrombolysis. 51, 4, p. 890-896 7 p.Research output: Contribution to journal › Review article › peer-review
2 Scopus citations -
Genetic variants associated with therapy-related cardiomyopathy among childhood cancer survivors of African Ancestry
Sapkota, Y., Qin, N., Ehrhardt, M. J., Wang, Z., Chen, Y., Wilson, C. L., Estepp, J., Rai, P., Hankins, J. S., Burridge, P. W., Jefferies, J. L., Zhang, J., Hudson, M. M., Robison, L. L., Armstrong, G. T., Mulrooney, D. A. & Yasui, Y., May 1 2021, In: Cancer Research. 81, 9, p. 2556-2565 10 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Structural and functional characterization of a Nav1.5-mitochondrial couplon
Pérez-Hernández, M., Leo-Macias, A., Keegan, S., Jouni, M., Kim, J. C., Agullo-Pascual, E., Vermij, S., Zhang, M., Liang, F. X., Burridge, P., Fenyo, D., Rothenberg, E. & Delmar, M., 2021, (Accepted/In press) In: Circulation research. p. 419-432 14 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Targeting OCT3 attenuates doxorubicin-induced cardiac injury
Huang, K. M., Thomas, M. Z., Magdy, T., Eisenmann, E. D., Uddin, M. E., DiGiacomo, D. F., Pan, A., Keiser, M., Otter, M., Xia, S. H., Li, Y., Jin, Y., Fu, Q., Gibson, A. A., Bonilla, I. M., Carnes, C. A., Corps, K. N., Coppola, V., Smith, S. A., Addison, D. & 12 others, , Feb 2 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 5, e2020168118.Research output: Contribution to journal › Article › peer-review
2 Scopus citations