• 2821 Citations
20022025
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Personal profile

Research Interests

We use human induced pluripotent stem cells (hiPSCs) to understand the role of the genome in influencing drug efficacy and side effects as well as complex disease traits. We are also interested in pluripotency, differentiation methods, cardiac regenerative medicine, direct reprogramming, long QT syndrome, atrial fibrillation, peripheral artery disease, and hiPSC models of cancer. Along with the hiPSC model, we use a combination of whole genome sequencing, automation and robotics, high-throughput drug screening, high-content imaging, and electrophysiological testing.

Education/Academic qualification

PhD, University of Nottingham, UK

… → 2008

Keywords

  • Adverse Drug Reactions
  • Bioengineering
  • Bioinformatics
  • Breast Cancer
  • Cardiology
  • Drug Discovery
  • Regenerative Medicine
  • Stem Cells
  • Alzheimer's Disease
  • Arrhythmias
  • Atherosclerosis
  • Cardiovascular Diseases

Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 2 Similar Profiles
Induced Pluripotent Stem Cells Medicine & Life Sciences
Cardiac Myocytes Medicine & Life Sciences
Pluripotent Stem Cells Medicine & Life Sciences
Stem cells Chemical Compounds
Preclinical Drug Evaluations Medicine & Life Sciences
Pharmaceutical Preparations Medicine & Life Sciences
Regenerative Medicine Medicine & Life Sciences
Stem Cells Medicine & Life Sciences

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Grants 2015 2025

Plasminogen Activator Inhibitor 1
Fibrosis
Mutation
Cardiomyopathies
Cardiac Myocytes
Induced Pluripotent Stem Cells
Cardiac Myocytes
Doxorubicin
Anthracyclines
Clustered Regularly Interspaced Short Palindromic Repeats
Doxorubicin
Single Nucleotide Polymorphism
Induced Pluripotent Stem Cells
Clustered Regularly Interspaced Short Palindromic Repeats
Pediatrics
Induced Pluripotent Stem Cells
Anthracyclines
Single Nucleotide Polymorphism
Survivors
Clustered Regularly Interspaced Short Palindromic Repeats
Doxorubicin
Single Nucleotide Polymorphism
Induced Pluripotent Stem Cells
Quantitative Trait Loci
Cardiac Myocytes

Research Output 2002 2019

Are These Cardiomyocytes? Protocol Development Reveals Impact of Sample Preparation on the Accuracy of Identifying Cardiomyocytes by Flow Cytometry

Waas, M., Weerasekera, R., Kropp, E. M., Romero-Tejeda, M., Poon, E. N., Boheler, K. R., Burridge, P. & Gundry, R. L., Feb 12 2019, In : Stem cell reports. 12, 2, p. 395-410 16 p.

Research output: Contribution to journalArticle

Flow cytometry
Stem cells
Cardiac Myocytes
Flow Cytometry
Troponin
1 Citation (Scopus)

HiPSCs in cardio-oncology: Deciphering the genomics

Pinheiro, E. A., Fetterman, K. A. & Burridge, P., Apr 15 2019, In : Cardiovascular research. 115, 5, p. 935-948 14 p.

Research output: Contribution to journalReview article

Open Access
Induced Pluripotent Stem Cells
Genomics
Genome-Wide Association Study
Clustered Regularly Interspaced Short Palindromic Repeats
Pharmaceutical Preparations

Late onset heart failure after childhood chemotherapy

Hilfiker-Kleiner, D., Ardehali, H., Fischmeister, R., Burridge, P., Hirsch, E. & Lyon, A. R., Mar 7 2019, In : European heart journal. 40, 10, p. 798-800 3 p.

Research output: Contribution to journalArticle

Open Access
Heart Failure
Drug Therapy

Unraveling Difficult Answers: From Genotype to Phenotype in Coronary Artery Disease

Magdy, T. & Burridge, P., Feb 7 2019, In : Cell Stem Cell. 24, 2, p. 203-205 3 p.

Research output: Contribution to journalShort survey

Coronary Artery Disease
Genotype
Phenotype
Induced Pluripotent Stem Cells
Intergenic DNA
11 Citations (Scopus)

Human Induced Pluripotent Stem Cell (hiPSC)-Derived Cells to Assess Drug Cardiotoxicity: Opportunities and Problems

Magdy, T., Schuldt, A. J. T., Wu, J. C., Bernstein, D. & Burridge, P., Jan 6 2018, In : Annual Review of Pharmacology and Toxicology. 58, p. 83-103 21 p.

Research output: Contribution to journalReview article

Induced Pluripotent Stem Cells
Stem cells
Preclinical Drug Evaluations
Pharmaceutical Preparations
Screening