Grants per year
Personal profile
Research Interests
We use human induced pluripotent stem cells (hiPSCs) to understand the role of the genome in influencing drug efficacy and side effects as well as complex disease traits. We are also interested in pluripotency, differentiation methods, cardiac regenerative medicine, direct reprogramming, long QT syndrome, atrial fibrillation, peripheral artery disease, and hiPSC models of cancer. Along with the hiPSC model, we use a combination of whole genome sequencing, automation and robotics, high-throughput drug screening, high-content imaging, and electrophysiological testing.
Education/Academic qualification
PhD, University of Nottingham
… → 2008
Research interests
- Adverse Drug Reactions
- Bioengineering
- Bioinformatics
- Breast Cancer
- Cardiology
- Drug Discovery
- Regenerative Medicine
- Stem Cells
- Alzheimer's Disease
- Arrhythmias
- Atherosclerosis
- Cardiovascular Diseases
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Grants
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CardioExcyte 96 System for Pharmacology Research at Northwestern University
Abdulkadir, S. A., Ardehali, H., Arora, R. K., Burridge, P., George Jr, A. L., Kearney, J. A., McNally, E. M., Schiltz, G. E., Silverman, R. B., Watterson, D. M. & Wilsbacher, L. D.
Office of the Director, National Institutes of Health
6/15/20 → 6/14/21
Project: Research project
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Assessing molecular mechanisms underlying novel cardiomyopathy risk loci in survivors of childhood cancer
St. Jude Children's Research Hospital
6/11/20 → 4/30/21
Project: Research project
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Research Output
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Association of GSTM1 null variant with anthracycline-related cardiomyopathy after childhood cancer—A Children's Oncology Group ALTE03N1 report
Singh, P., Wang, X., Hageman, L., Chen, Y., Magdy, T., Landier, W., Ginsberg, J. P., Neglia, J. P., Sklar, C. A., Castellino, S. M., Dreyer, Z. E., Hudson, M. M., Robison, L. L., Blanco, J. G., Relling, M. V., Burridge, P. & Bhatia, S., Sep 1 2020, In: Cancer. 126, 17, p. 4051-4058 8 p.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
Cellular model systems to study cardiovascular injury from chemotherapy
Fonoudi, H. & Burridge, P. W., 2020, (Accepted/In press) In: Journal of thrombosis and thrombolysis.Research output: Contribution to journal › Review article › peer-review
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Doxorubicin-induced ascension of resident cardiac macrophages
Burridge, P. W. & Thorp, E. B., 2020, (Accepted/In press) In: Circulation research. p. 628-630 3 p.Research output: Contribution to journal › Review article › peer-review
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Generating a Cost-Effective, Weekend-Free Chemically Defined Human Induced Pluripotent Stem Cell (hiPSC) Culture Medium
Fonoudi, H., Lyra-Leite, D. M., Javed, H. A. & Burridge, P. W., Jun 1 2020, In: Current Protocols in Stem Cell Biology. 53, 1, e110.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
GS-967 and eleclazine block sodium channels in human induced pluripotent stem cell-derived cardiomyocytes
Potet, F., Egecioglu, D. E., Burridge, P. W. & George, A. L., Nov 1 2020, In: Molecular pharmacology. 98, 5, p. 540-547 8 p.Research output: Contribution to journal › Article › peer-review
Open Access