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Paul Burridge

  • 3443 Citations
20022020

Research output per year

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Personal profile

Research Interests

We use human induced pluripotent stem cells (hiPSCs) to understand the role of the genome in influencing drug efficacy and side effects as well as complex disease traits. We are also interested in pluripotency, differentiation methods, cardiac regenerative medicine, direct reprogramming, long QT syndrome, atrial fibrillation, peripheral artery disease, and hiPSC models of cancer. Along with the hiPSC model, we use a combination of whole genome sequencing, automation and robotics, high-throughput drug screening, high-content imaging, and electrophysiological testing.

Education/Academic qualification

PhD, University of Nottingham

… → 2008

Research interests

  • Adverse Drug Reactions
  • Bioengineering
  • Bioinformatics
  • Breast Cancer
  • Cardiology
  • Drug Discovery
  • Regenerative Medicine
  • Stem Cells
  • Alzheimer's Disease
  • Arrhythmias
  • Atherosclerosis
  • Cardiovascular Diseases

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Grants

CardioExcyte 96 System for Pharmacology Research at Northwestern University

Abdulkadir, S. A., Ardehali, H., Arora, R. K., Burridge, P., George Jr, A. L., Kearney, J. A., McNally, E. M., Schiltz, G. E., Silverman, R. B., Watterson, D. M. & Wilsbacher, L. D.

National Institutes of Health

6/15/20 → 6/14/21

Project: Research project

    • Mechanistic insights into the role of mitochondrial iron in doxorubicin-induced cardiomyopathy using human induced pluripotent stem cells

    Ardehali, H. & Burridge, P.

    National Heart, Lung, and Blood Institute

    3/15/20 → 2/29/24

    Project: Research project

    • Subproject for Institution # SP0053781

    Burridge, P.

    Leducq Foundation

    1/1/20 → 12/31/24

    Project: Research project

    • A Patient-Specific hiPSC Model of Nilotinib-Induced Peripheral Artery Disease Pharmacogenomics

    Burridge, P. & Quaggin, S. E.

    American Heart Association

    1/1/20 → 12/31/21

    Project: Research project

    • The Who and Why of Anthracycline-related Cardiotoxicity in Childhood Cancer Survivors

    Burridge, P.

    University of Alabama at Birmingham, Leukemia & Lymphoma Society

    7/1/19 → 6/30/21

    Project: Research project

    • Research Output

    Human In Vitro Models for Assessing the Genomic Basis of Chemotherapy-Induced Cardiovascular Toxicity

    Pinheiro, E. A., Magdy, T. & Burridge, P. W., Jan 1 2020, (Accepted/In press) In : Journal of Cardiovascular Translational Research.

    Research output: Contribution to journal › Review article

    • 1 Scopus citations

    Negligible-Cost and Weekend-Free Chemically Defined Human iPSC Culture

    Kuo, H. H., Gao, X., DeKeyser, J. M., Fetterman, K. A., Pinheiro, E. A., Weddle, C. J., Fonoudi, H., Orman, M. V., Romero-Tejeda, M., Jouni, M., Blancard, M., Magdy, T., Epting, C. L., George, A. L. & Burridge, P. W., Feb 11 2020, In : Stem cell reports. 14, 2, p. 256-270 15 p.

    Research output: Contribution to journal › Article

    Open Access
    • 1 Scopus citations

    Precise and Cost-Effective Nanopore Sequencing for Post-GWAS Fine-Mapping and Causal Variant Identification

    Magdy, T., Kuo, HH. H. & Burridge, P. W., Apr 24 2020, In : iScience. 23, 4, 100971.

    Research output: Contribution to journal › Article

    Open Access

    • Are These Cardiomyocytes? Protocol Development Reveals Impact of Sample Preparation on the Accuracy of Identifying Cardiomyocytes by Flow Cytometry

    Waas, M., Weerasekera, R., Kropp, E. M., Romero-Tejeda, M., Poon, E. N., Boheler, K. R., Burridge, P. W. & Gundry, R. L., Feb 12 2019, In : Stem cell reports. 12, 2, p. 395-410 16 p.

    Research output: Contribution to journal › Article

    • 3 Scopus citations

    Genetic Mosaicism in Calmodulinopathy

    Wren, L. M., Jiménez-Jáimez, J., Al-Ghamdi, S., Al-Aama, J. Y., Bdeir, A., Al-Hassnan, Z. N., Kuan, J. L., Foo, R. Y., Potet, F., Johnson, C. N., Aziz, M. C., Carvill, G. L., Kaski, J. P., Crotti, L., Perin, F., Monserrat, L., Burridge, P. W., Schwartz, P. J., Chazin, W. J., Bhuiyan, Z. A. & 1 others, George, A. L., Sep 1 2019, In : Circulation: Genomic and Precision Medicine. 12, 9, p. 375-385 11 p., e002581.

    Research output: Contribution to journal › Article

    Open Access
    • 4 Scopus citations