Grants per year
Personal profile
Research Interests
Our lab is interested in the effects of oxygen on cell metabolism, and in the molecular mechanisms underlying cellular oxygen sensing. The signaling pathways activated by hypoxia, and their regulation of transcriptional and post-translational responses in diverse cell types are also of major interest. Current studies focus on the role of mitochondrial redox signaling in the development of pulmonary hypertension. Other current studies focus on cardiomyocyte regeneration in the heart and molecular factors that regulate hypertrophic and hyperplastic remodeling responses.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
PhD, Physiology, Albany Medical College
… → 1980
Research interests keywords
- Cancer Biology
- Cardiovascular Diseases
- Cell Biology
- Lungs / Breathing Problems
- Metabolism
- Parkinson’s Disease
- Pulmonary Hypertension
- Signal Transduction
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Collaborations and top research areas from the last five years
Grants
- 71 Finished
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Redox Regulation in the Perinatal Pulmonary Vasculature
Schumacker, P. T. (PD/PI) & Perez, M. (Co-Investigator)
National Heart, Lung, and Blood Institute, National Institutes of Health
9/15/19 → 6/30/22
Project: Research project
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Redox Regulation in the Perinatal Pulmonary Vasculature
Schumacker, P. T. (PD/PI)
National Heart, Lung, and Blood Institute, National Institutes of Health
9/15/19 → 6/30/21
Project: Research project
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Molecular and Cellular Mechanisms of Parkinson's Disease
Schumacker, P. T. (PD/PI)
Northwestern University, JPB Foundation
11/1/18 → 10/31/21
Project: Research project
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Disordered Proteostasis as a Driver of Disease in the Aging Lung
Schumacker, P. T. (PD/PI)
Northwestern University, National Institutes of Health
9/15/18 → 7/31/19
Project: Research project
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Subproject for Institution # SP0046610
Schumacker, P. T. (PD/PI) & Surmeier Jr, D. J. (PD/PI)
Michael J. Fox Foundation for Parkinson's Research
1/1/18 → 4/16/21
Project: Research project
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Editorial Position of the American Thoracic Society Journal Family on the Evolving Role of Artificial Intelligence in Scientific Research and Review
Seam, N., Chotirmall, S. H., Martinez, F. J., Halayko, A. J., Harhay, M. O., Davis, S. D., Schumacker, P. T., Tighe, R. M., Burkart, K. M. & Cooke, C., Jan 1 2025, In: American journal of respiratory and critical care medicine. 211, 1, p. 1-3 3 p.Research output: Contribution to journal › Editorial › peer-review
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Bronchopulmonary Dysplasia and Cell Senescence: A Case of Old Lungs in Young Infants?
Schumacker, P. T., Feb 2024, In: American journal of respiratory cell and molecular biology. 70, 2, p. 85-86 2 p.Research output: Contribution to journal › Editorial › peer-review
Open Access -
Correction to: NDUFS4 regulates cristae remodeling in diabetic kidney disease (Nature Communications, (2024), 15, 1, (1965), 10.1038/s41467-024-46366-w)
Mise, K., Long, J., Galvan, D. L., Ye, Z., Fan, G., Sharma, R., Serysheva, I. I., Moore, T. I., Jeter, C. R., Anna Zal, M., Araki, M., Wada, J., Schumacker, P. T., Chang, B. H. & Danesh, F. R., Dec 2024, In: Nature communications. 15, 1, 3022.Research output: Contribution to journal › Comment/debate › peer-review
Open Access1 Scopus citations -
Mitochondrial respiration in microglia is essential for response to demyelinating injury but not proliferation
Stoolman, J. S., Grant, R. A., Poor, T. A., Weinberg, S. E., D’Alessandro, K. B., Tan, J., Hu, J. Y. S., Zerrer, M. E., Wood, W. A., Harding, M. C., Soni, S., Ridge, K. M., Schumacker, P. T., Budinger, G. R. S. & Chandel, N. S., Aug 2024, In: Nature Metabolism. 6, 8, p. 1492-1504 13 p.Research output: Contribution to journal › Letter › peer-review
8 Scopus citations -
Mitochondria regulate proliferation in adult cardiac myocytes
Waypa, G. B., Smith, K. A., Mungai, P. T., Dudley, V. J., Helmin, K. A., Singer, B. D., Peek, C. B., Bass, J., Nelson, L., Shah, S. J., Ofman, G., Wasserstrom, J. A., Muller, W. A., Misharin, A. V., Budinger, G. R. S., Abdala-Valencia, H., Chandel, N. S., Dokic, D., Bartom, E. & Zhang, S. & 5 others, , Jul 1 2024, In: Journal of Clinical Investigation. 134, 13, e165482.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations
Datasets
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Source data for "Ca2+ channels couple spiking to mitochondrial metabolism in substantia nigra dopaminergic neurons"
Zampese, E. (Contributor), Wokosin, D. L. (Contributor), Guzman, J. N. (Contributor), Tkatch, T. (Contributor), Kondapalli, J. (Contributor), Surmeier, W. C. (Contributor), D'Alessandro, K. B. (Contributor), De Stefani, D. (Contributor), Rizzuto, R. (Contributor), Iino, M. (Contributor), Molkentin, J. D. (Contributor), Chandel, N. S. (Contributor), Schumacker, P. T. (Contributor) & Surmeier, D. J. (Contributor), ZENODO, Aug 8 2022
DOI: 10.5281/zenodo.6949450, https://zenodo.org/records/6949450
Dataset