• 23287 Citations
1979 …2021

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

2020

Author Correction: Dopamine metabolism by a monoamine oxidase mitochondrial shuttle activates the electron transport chain (Nature Neuroscience, (2020), 23, 1, (15-20), 10.1038/s41593-019-0556-3)

Graves, S. M., Xie, Z., Stout, K. A., Zampese, E., Burbulla, L. F., Shih, J. C., Kondapalli, J., Patriarchi, T., Tian, L., Brichta, L., Greengard, P., Krainc, D., Schumacker, P. T. & Surmeier, D. J., Feb 1 2020, In : Nature Neuroscience. 23, 2, 1 p.

Research output: Contribution to journalComment/debate

Open Access

Dopamine metabolism by a monoamine oxidase mitochondrial shuttle activates the electron transport chain

Graves, S. M., Xie, Z., Stout, K. A., Zampese, E., Burbulla, L. F., Shih, J. C., Kondapalli, J., Patriarchi, T., Tian, L., Brichta, L., Greengard, P., Krainc, D., Schumacker, P. T. & Surmeier, D. J., Jan 1 2020, In : Nature Neuroscience. 23, 1, p. 15-20 6 p.

Research output: Contribution to journalArticle

1 Scopus citations
2019

Drp1S600 phosphorylation regulates mitochondrial fission and progression of nephropathy in diabetic mice

Galvan, D. L., Long, J., Green, N., Chang, B. H., Lin, J. S., Schumacker, P., Truong, L. D., Overbeek, P. & Danesh, F. R., Jan 1 2019, In : Journal of Clinical Investigation. 129, 7, p. 2807-2823 17 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Efferocytosis Fuels Requirements of Fatty Acid Oxidation and the Electron Transport Chain to Polarize Macrophages for Tissue Repair

Zhang, S., Weinberg, S., DeBerge, M., Gainullina, A., Schipma, M., Kinchen, J. M., Ben-Sahra, I., Gius, D. R., Yvan-Charvet, L., Chandel, N. S., Schumacker, P. T. & Thorp, E. B., Feb 5 2019, In : Cell Metabolism. 29, 2, p. 443-456.e5

Research output: Contribution to journalArticle

20 Scopus citations

Happy 30th anniversary to the Red Journal!

Schumacker, P. T., Jan 1 2019, In : American journal of respiratory cell and molecular biology. 61, 1, p. 1-2 2 p.

Research output: Contribution to journalEditorial

Open Access

Mitochondrial complex III is essential for suppressive function of regulatory T cells

Weinberg, S. E., Singer, B. D., Steinert, E. M., Martinez, C. A., Mehta, M. M., Martínez-Reyes, I., Gao, P., Helmin, K. A., Abdala-Valencia, H., Sena, L. A., Schumacker, P. T., Turka, L. A. & Chandel, N. S., Jan 24 2019, In : Nature. 565, 7740, p. 495-499 5 p.

Research output: Contribution to journalLetter

43 Scopus citations

Roles of HIF1 and HIF2 in pulmonary hypertension: It all depends on the context

Waypa, G. B. & Schumacker, P. T., Dec 1 2019, In : European Respiratory Journal. 54, 6, 1901929.

Research output: Contribution to journalReview article

Open Access

Sensors and signals: the role of reactive oxygen species in hypoxic pulmonary vasoconstriction

Smith, K. A. & Schumacker, P. T., Feb 15 2019, In : Journal of Physiology. 597, 4, p. 1033-1043 11 p.

Research output: Contribution to journalArticle

5 Scopus citations
2018

JNK2 up-regulates hypoxia-inducible factors and contributes to hypoxia-induced erythropoiesis and pulmonary hypertension

Sala, M. A., Chen, C., Zhang, Q., Do-Umehara, H. C., Wu, W., Misharin, A. V., Waypa, G. B., Fang, D., Budinger, G. R. S., Liu, S., Chandel, N. S., Schumacker, P. T., Sznajder, J. I. & Liu, J., Jan 1 2018, In : Journal of Biological Chemistry. 293, 1, p. 271-284 14 p.

Research output: Contribution to journalArticle

5 Scopus citations

mRNA-binding protein tristetraprolin is essential for cardiac response to iron deficiency by regulating mitochondrial function

Sato, T., Chang, H. C., Bayeva, M., Shapiro, J. S., Ramos-Alonso, L., Kouzu, H., Jiang, X., Liu, T., Yar, S., Sawicki, K. T., Chen, C., Martínez-Pastor, M. T., Stumpo, D. J., Schumacker, P. T., Blackshear, P. J., Ben-Sahra, I., Puig, S. & Ardehali, H., Jul 3 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 27, p. E6291-E6300

Research output: Contribution to journalArticle

6 Scopus citations

MRNA-binding protein tristetraprolin is essential for cardiac response to iron deficiency by regulating mitochondrial function

Sato, T., Chang, H. C., Bayeva, M., Shapiro, J. S., Alonso, R. L., Kouzu, H., Jiang, X., Liu, T., Yar, S., Sawicki, K. T., Chen, C., Martinez-Pastor, M. T., Stumpo, D. J., Schumacker, P. T., Blackshear, P. J., Sahra, B. I., Puig, S. & Ardehali, H., Dec 1 2018, In : Sapporo Medical journal. 87, 1-6, p. 98-99 2 p.

Research output: Contribution to journalArticle

1 Scopus citations

Systemic isradipine treatment diminishes calcium-dependent mitochondrial oxidant stress

Guzman, J. N., Ilijic, E., Yang, B., Sanchez-Padilla, J., Wokosin, D., Galtieri, D., Kondapalli, J., Schumacker, P. T. & Surmeier, D. J., Jun 1 2018, In : Journal of Clinical Investigation. 128, 6, p. 2266-2280 15 p.

Research output: Contribution to journalArticle

25 Scopus citations

The Phillip Morris Foundation for a smoke-free world: A cause for concern

Goldberg, D. S., Lederer, D. J., MacKenzie, E. J., Moss, M., Samet, J. M., Schumacker, P. T., Wedzicha, J. A. & Wynia, M. K., Nov 2018, In : Annals of the American Thoracic Society. 15, 11, p. 1269-1272 4 p.

Research output: Contribution to journalArticle

1 Scopus citations
2017

Calcium and Parkinson's disease

Surmeier Jr, D. J., Schumacker, P. T., Guzman, J. D., Ilijic, E., Yang, B. & Zampese, E., Feb 19 2017, In : Biochemical and Biophysical Research Communications. 483, 4, p. 1013-1019 7 p.

Research output: Contribution to journalReview article

59 Scopus citations

Corrigendum: Snf1-related kinase improves cardiac mitochondrial efficiency and decreases mitochondrial uncoupling

Rines, A. K., Chang, H. C., Wu, R., Sato, T., Khechaduri, A., Kouzu, H., Shapiro, J., Shang, M., Burke, M. A., Abdelwahid, E., Jiang, X., Chen, C., Rawlings, T. A., Lopaschuk, G. D., Schumacker, P. T., Abel, E. D. & Ardehali, H., Aug 30 2017, In : Nature communications. 8, 1 p.

Research output: Contribution to journalComment/debate

Real-time in vivo mitochondrial redox assessment confirms enhanced mitochondrial reactive oxygen species in diabetic nephropathy

Galvan, D. L., Badal, S. S., Long, J., Chang, B. H., Schumacker, P. T., Overbeek, P. A. & Danesh, F. R., Nov 2017, In : Kidney international. 92, 5, p. 1282-1287 6 p.

Research output: Contribution to journalArticle

17 Scopus citations

Redox signaling during hypoxia in mammalian cells

Smith, K. A., Waypa, G. B. & Schumacker, P. T., Oct 2017, In : Redox Biology. 13, p. 228-234 7 p.

Research output: Contribution to journalReview article

44 Scopus citations

Sirt3 protects dopaminergic neurons from mitochondrial oxidative stress

Shi, H., Deng, H. X., Gius, D., Schumacker, P. T., Surmeier, D. J. & Ma, Y. C., May 15 2017, In : Human molecular genetics. 26, 10, p. 1915-1926 12 p.

Research output: Contribution to journalArticle

23 Scopus citations

Snf1-related kinase improves cardiac mitochondrial efficiency and decreases mitochondrial uncoupling

Rines, A. K., Chang, H. C., Wu, R., Sato, T., Khechaduri, A., Kouzu, H., Shapiro, J., Shang, M., Burke, M. A., Jiang, X., Chen, C., Rawlings, T. A., Lopaschuk, G. D., Schumacker, P. T., Abel, E. D. & Ardehali, H., Jan 24 2017, In : Nature communications. 8, 14095.

Research output: Contribution to journalArticle

8 Scopus citations

The mitochondrial respiratory chain is essential for haematopoietic stem cell function

Ansó, E., Weinberg, S. E., Diebold, L. P., Thompson, B. J., Malinge, S., Schumacker, P. T., Liu, X., Zhang, Y., Shao, Z., Steadman, M., Marsh, K. M., Xu, J., Crispino, J. D. & Chandel, N. S., May 31 2017, In : Nature Cell Biology. 19, 6, p. 614-625 12 p.

Research output: Contribution to journalArticle

65 Scopus citations
2016

A new beginning for the red journal

Schumacker, P. T., Oct 2016, In : American journal of respiratory cell and molecular biology. 55, 4, p. v-vi

Research output: Contribution to journalEditorial

Determinants of Selective Vulnerability of Dopamine Neurons in Parkinson's Disease

Zampese, E., Galtieri, D. J., Schumacker, P. T. & Surmeier Jr, D. J., Jan 1 2016, Handbook of Behavioral Neuroscience. Elsevier B.V., p. 821-837 17 p. (Handbook of Behavioral Neuroscience; vol. 24).

Research output: Chapter in Book/Report/Conference proceedingChapter

Dynamin-related protein 1 deficiency improves mitochondrial fitness and protects against progression of diabetic nephropathy

Ayanga, B. A., Badal, S. S., Wang, Y., Galvan, D. L., Chang, B. H., Schumacker, P. T. & Danesh, F. R., Jan 1 2016, In : Journal of the American Society of Nephrology. 27, 9, p. 2733-2747 15 p.

Research output: Contribution to journalArticle

37 Scopus citations

Intermediate filament aggregates cause mitochondrial dysmotility and increase energy demands in giant axonal neuropathy

Israeli, E., Dryanovski, D. I., Schumacker, P. T., Chandel, N. S., Singer, J. D., Julien, J. P., Goldman, R. D. & Opal, P., Jun 1 2016, In : Human molecular genetics. 25, 11, p. 2143-2157 15 p.

Research output: Contribution to journalArticle

14 Scopus citations

Life on the edge: Determinants of selective neuronal vulnerability in Parkinson's disease

Surmeier Jr, D. J., Zampese, E., Galtieri, D. & Schumacker, P. T., Jun 8 2016, Mitochondrial Dysfunction in Neurodegenerative Disorders: Second Edition. Springer International Publishing, p. 141-173 33 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Mitochondrial function in sepsis

Arulkumaran, N., Deutschman, C. S., Pinsky, M. R., Zuckerbraun, B., Schumacker, P. T., Gomez, H., Gomez, A., Murray, P. & Kellum, J. A., Mar 1 2016, In : Shock. 45, 3, p. 271-281 11 p.

Research output: Contribution to journalReview article

45 Scopus citations

O2 sensing, mitochondria and ROS signaling: The fog is lifting

Waypa, G. B., Smith, K. A. & Schumacker, P. T., Feb 1 2016, In : Molecular Aspects of Medicine. 47-48, p. 76-89 14 p.

Research output: Contribution to journalReview article

61 Scopus citations
2015

Asbestos-induced pulmonary fibrosis is augmented in 8-oxoguanine DNA glycosylase knockout mice

Cheresh, P., Morales-Nebreda, L., Kim, S. J., Yeldandi, A., Williams, D. B., Cheng, Y., Mutlu, G. M., Scott Budinger, G. R., Ridge, K., Schumacker, P. T., Bohr, V. A. & Kamp, D. W., Jan 1 2015, In : American journal of respiratory cell and molecular biology. 52, 1, p. 25-36 12 p.

Research output: Contribution to journalArticle

19 Scopus citations

Corrigendum: Oxidant stress evoked by pacemaking in dopaminergic neurons is attenuated by DJ-1(Nature (2010) 468 (696-700) 10.1038/nature09536)

Guzman, J. N., Sanchez-Padilla, J., Wokosin, D., Kondapalli, J., Ilijic, E., Schumacker, P. T. & Surmeier, D. J., May 20 2015, In : Nature. 521, 7552, 1 p.

Research output: Contribution to journalComment/debate

2 Scopus citations

Cyclic stretch stimulates mitochondrial reactive oxygen species and Nox4 signaling in pulmonary artery smooth muscle cells

Wedgwood, S., Lakshminrusimha, S., Schumacker, P. T. & Steinhorn, R. H., Jul 15 2015, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 309, 2, p. L196-L203

Research output: Contribution to journalArticle

15 Scopus citations

Hypoxia inducible factor signaling and experimental persistent pulmonary hypertension of the newborn

Wedgwood, S., Lakshminrusimha, S., Schumacker, P. T. & Steinhorn, R. H., Jan 1 2015, In : Frontiers in Pharmacology. 6, MAR, 47.

Research output: Contribution to journalArticle

12 Scopus citations

Identification of fumarate hydratase inhibitors with nutrient-dependent cytotoxicity

Takeuchi, T., Schumacker, P. T. & Kozmin, S. A., Jan 21 2015, In : Journal of the American Chemical Society. 137, 2, p. 564-567 4 p.

Research output: Contribution to journalArticle

7 Scopus citations

Mouse lung development and NOX1 induction during hyperoxia are developmentally regulated and mitochondrial ROS dependent

Datta, A., Kim, G. A., Taylor, J. M., Gugino, S. F., Farrow, K. N., Schumacker, P. T. & Berkelhamer, S. K., Aug 18 2015, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 309, 4, p. L369-L377

Research output: Contribution to journalArticle

28 Scopus citations

Reactive Oxygen Species in Cancer: A Dance with the Devil

Schumacker, P. T., Feb 9 2015, In : Cancer Cell. 27, 2, p. 156-157 2 p.

Research output: Contribution to journalShort survey

154 Scopus citations
2014

Cellular and molecular mechanisms of O2 sensing

Swenson, ER. (ed.), Bartsch, P. (ed.) & Schumacker, P. T., Jul 1 2014, High Altitude: Human Adaptation to Hypoxia: Human Adaptation to Hypoxia. Springer New York, Vol. 9781461487722. p. 1-22 22 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations

Mitochondria in lung biology and pathology: More than just a powerhouse

Schumacker, P. T., Gillespie, M. N., Nakahira, K., Choi, A. M. K., Crouser, E. D., Piantadosi, C. A. & Bhattacharya, J., Jun 1 2014, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 306, 11, p. L962-L974

Research output: Contribution to journalArticle

71 Scopus citations

Mitochondrial oxidant stress in locus coeruleus is regulated by activity and nitric oxide synthase

Sanchez-Padilla, J., Guzman, J. N., Ilijic, E., Kondapalli, J., Galtieri, D. J., Yang, B., Schieber, S., Oertel, W., Wokosin, D., Schumacker, P. T. & Surmeier, D. J., Jun 2014, In : Nature Neuroscience. 17, 6, p. 832-840 9 p.

Research output: Contribution to journalArticle

64 Scopus citations

Mitochondrial ROS in cancer: Initiators, amplifiers or an Achilles' heel?

Sabharwal, S. S. & Schumacker, P. T., Oct 27 2014, In : Nature Reviews Cancer. 14, 11, p. 709-721 13 p.

Research output: Contribution to journalReview article

520 Scopus citations

Mitochondria-targeted Ogg1 and aconitase-2 prevent oxidant-induced mitochondrial DNA damage in alveolar epithelial cells

Kim, S. J., Cheresh, P., Williams, D., Cheng, Y., Ridge, K., Schumacker, P. T., Weitzman, S., Bohr, V. A. & Kamp, D. W., Feb 28 2014, In : Journal of Biological Chemistry. 289, 9, p. 6165-6176 12 p.

Research output: Contribution to journalArticle

47 Scopus citations

Regulation of hypoxia-induced pulmonary hypertension by vascular smooth muscle hypoxia-inducible factor-1α

Ball, M. K., Waypa, G. B., Mungai, P. T., Nielsen, J. M., Czech, L., Dudley, V. J., Beussink, L., Dettman, R., Berkelhamer, S. K., Steinhorn, R. H., Shah, S. J. & Schumacker, P. T., Feb 1 2014, In : American Journal of Respiratory and Critical Care Medicine. 189, 3, p. 314-324 11 p.

Research output: Contribution to journalArticle

98 Scopus citations

The 'mitoflash' probe cpYFP does not respond to superoxide

Schwarzländer, M., Wagner, S., Ermakova, Y. G., Belousov, V. V., Radi, R., Beckman, J. S., Buettner, G. R., Demaurex, N., Duchen, M. R., Forman, H. J., Fricker, M. D., Gems, D., Halestrap, A. P., Halliwell, B., Jakob, U., Johnston, I. G., Jones, N. S., Logan, D. C., Morgan, B., Müller, F. L. & 8 others, Nicholls, D. G., Remington, S. J., Schumacker, P. T., Winterbourn, C. C., Sweetlove, L. J., Meyer, A. J., Dick, T. P. & Murphy, M. P., Oct 23 2014, In : Nature. 514, 7523, p. E12-E14

Research output: Contribution to journalLetter

77 Scopus citations

Update in pulmonary vascular diseases 2013

Hassoun, P. M. & Schumacker, P. T., Oct 1 2014, In : American journal of respiratory and critical care medicine. 190, 7, p. 738-743 6 p.

Research output: Contribution to journalArticle

1 Scopus citations
2013

Calcium, bioenergetics, and neuronal vulnerability in Parkinson's disease

Surmeier, D. J. & Schumacker, P. T., Apr 12 2013, In : Journal of Biological Chemistry. 288, 15, p. 10736-10741 6 p.

Research output: Contribution to journalReview article

107 Scopus citations

Calcium entry and α-synuclein inclusions elevate dendritic mitochondrial oxidant stress in dopaminergic neurons

Dryanovski, D. I., Guzman, J. N., Xie, Z., Galteri, D. J., Volpicelli-Daley, L. A., Lee, V. M. Y., Miller, R. J., Schumacker, P. T. & James Surmeier, D., Jun 17 2013, In : Journal of Neuroscience. 33, 24, p. 10154-10164 11 p.

Research output: Contribution to journalArticle

108 Scopus citations

Cyclic stretch induces inducible nitric oxide synthase and soluble guanylate cyclase in pulmonary artery smooth muscle cells

Shah, M. R., Wedgwood, S., Czech, L., Kim, G. A., Lakshminrusimha, S., Schumacker, P. T., Steinhorn, R. H. & Farrow, K. N., Feb 1 2013, In : International journal of molecular sciences. 14, 2, p. 4334-4348 15 p.

Research output: Contribution to journalArticle

13 Scopus citations

Developmental differences in hyperoxia-induced oxidative stress and cellular responses in the murine lung

Berkelhamer, S. K., Kim, G. A., Radder, J. E., Wedgwood, S., Czech, L., Steinhorn, R. H. & Schumacker, P. T., May 9 2013, In : Free Radical Biology and Medicine. 61, p. 51-60 10 p.

Research output: Contribution to journalArticle

44 Scopus citations

Hypoxia-inducible factor-2α and TGF-β signaling interact to promote normoxic glomerular fibrogenesis

Hanna, C., Hubchak, S. C., Liang, X., Rozen-Zvi, B., Schumacker, P. T., Hayashida, T. & Schnaper, H. W., Nov 1 2013, In : American Journal of Physiology - Renal Physiology. 305, 9

Research output: Contribution to journalArticle

24 Scopus citations

Increased p22phox/Nox4 expression is involved in remodeling through hydrogen peroxide signaling in experimental persistent pulmonary hypertension of the newborn

Wedgwood, S., Lakshminrusimha, S., Czech, L., Schumacker, P. T. & Steinhorn, R. H., May 10 2013, In : Antioxidants and Redox Signaling. 18, 14, p. 1765-1776 12 p.

Research output: Contribution to journalReview article

38 Scopus citations