Paula H Stern

  • 5763 Citations
1963 …2018
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Research Output 1963 2018

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Article
2016
11 Citations (Scopus)

Elevated incidence of fractures in women with invasive breast cancer

Edwards, B. J., Gradishar, W. J., Smith, M. E., Pacheco, J. A., Holbrook, J., McKoy, J. M., Nardone, B., Tica, S., Godinez-Puig, V., Rademaker, A. W., Helenowski, I. B., Bunta, A. D., Stern, P. H., Rosen, S. T., West, D. P. & Guise, T. A., Feb 1 2016, In : Osteoporosis International. 27, 2, p. 499-507 9 p.

Research output: Contribution to journalArticle

Breast Neoplasms
Bone Fractures
Incidence
Bone Density
Cohort Studies
2014
8 Citations (Scopus)
Parathyroid Hormone-Related Protein
Bone Resorption
Osteogenesis
Antineoplastic Agents
Bone
2013
5 Citations (Scopus)
Annexins
Rats
Calcium
Kidney
Dentin
2012
31 Citations (Scopus)

Systemic delivery of oncolytic adenoviruses targeting transforming growth factor-β inhibits established bone metastasis in a prostate cancer mouse model

Hu, Z., Gupta, J., Zhang, Z., Gerseny, H., Berg, A., Chen, Y. J., Zhang, Z., Du, H., Brendler, C. B., Xiao, X., Pienta, K. J., Guise, T., Lee, C., Stern, P. H., Stock, S. R. & Seth, P., Aug 1 2012, In : Human Gene Therapy. 23, 8, p. 871-882 12 p.

Research output: Contribution to journalArticle

Transforming Growth Factors
Adenoviridae
Growth Factor Receptors
Prostatic Neoplasms
Neoplasm Metastasis
2011
5 Citations (Scopus)
Parathyroid Hormone
GTP-Binding Proteins
Genes
Heterotrimeric GTP-Binding Proteins
Bone Remodeling
9 Citations (Scopus)

Dose-dependent differential effects of risedronate on gene expression in osteoblasts

Wang, J. & Stern, P. H., Apr 15 2011, In : Biochemical Pharmacology. 81, 8, p. 1036-1042 7 p.

Research output: Contribution to journalArticle

Osteoblasts
Gene expression
Genes
Gene Expression
Diphosphonates
1 Citation (Scopus)

Lawrence G. Raisz November 13, 1925-August 25, 2010.

Bilezikian, J. P., Drezner, M., Kream, B., Stern, P., Clemens, T., Elderkin, A., Siris, E., Krane, S., Eisman, J., Arnold, A., Feyen, J., Hurley, M., Kawaguchi, H., Lorenzo, J., Peck, W., Pilbeam, C., Rowe, D., Martin, T. J., Hock, J., DeLuca, H. & 4 others, Rodan, S., Lukert, B., Chen, T. & Klein-Nulend, J., May 1 2011, In : Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 26, 5, p. 903-911 9 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Regulation of breast cancer-induced bone lesions by β-catenin protein signaling

Chen, Y., Shi, H. Y., Stock, S. R., Stern, P. H. & Zhang, M., Dec 9 2011, In : Journal of Biological Chemistry. 286, 49, p. 42575-42584 10 p.

Research output: Contribution to journalArticle

Catenins
Bone Neoplasms
Bone
Breast Neoplasms
Bone and Bones
10 Citations (Scopus)
Osteoclasts
Gene expression
Androgens
Monocytes
Estradiol
2010

In Memoriam: Lawrence Gideon Raisz Nove 13, 1925 - August 25, 2010.

Stern, PH., 2010, In : Bone. 47, p. 846-847 2 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Osteoblast proliferation on hydroxyapatite coated substrates prepared by right angle magnetron sputtering

Hong, Z., Mello, A., Yoshida, T., Luan, L., Stern, P. H., Rossi, A., Ellis, D. E. & Ketterson, J. B., Jun 1 2010, In : Journal of Biomedical Materials Research - Part A. 93, 3, p. 878-885 8 p.

Research output: Contribution to journalArticle

Osteoblasts
Durapatite
Hydroxyapatite
Magnetron sputtering
Coatings
11 Citations (Scopus)
Parathyroid Hormone
Osteoprotegerin
Calcitriol
Cells
Osteogenesis
2009
18 Citations (Scopus)

Direct inhibitory and indirect stimulatory effects of RAGE ligand S100 on sRANKL-induced osteoclastogenesis

Yoshida, T., Flegler, A., Kozlov, A. & Stern, P. H., Aug 1 2009, In : Journal of Cellular Biochemistry. 107, 5, p. 917-925 9 p.

Research output: Contribution to journalArticle

Cell proliferation
Osteogenesis
S100 Proteins
Conditioned Culture Medium
Ligands
21 Citations (Scopus)

Rho GTPase signaling and PTH 3-34, but not PTH 1-34, maintain the actin cytoskeleton and antagonize bisphosphonate effects in mouse osteoblastic MC3T3-E1 cells

Kazmers, N. H., Ma, S. A., Yoshida, T. & Stern, P. H., Jul 1 2009, In : Bone. 45, 1, p. 52-60 9 p.

Research output: Contribution to journalArticle

rho GTP-Binding Proteins
Focal Adhesions
Diphosphonates
Parathyroid Hormone
Actin Cytoskeleton
18 Citations (Scopus)

The small GTPase RhoA is crucial for MC3T3-E1 osteoblastic cell survival

Yoshida, T., Clark, M. F. & Stern, P. H., Apr 1 2009, In : Journal of Cellular Biochemistry. 106, 5, p. 896-902 7 p.

Research output: Contribution to journalArticle

Monomeric GTP-Binding Proteins
Cell Survival
Parathyroid Hormone
Cells
Caspase 3
2008
1 Citation (Scopus)

Increased osteoblast proliferation on hydroxyapatite thin coatings produced by right angle magnetron sputtering

Hong, Z., Mello, A., Yoshida, T., Luan, L., Stern, P. H., Rossi, A., Ellis, D. E. & Ketterson, J. B., Jan 22 2008, In : Key Engineering Materials. 361-363 I, p. 215-218 4 p.

Research output: Contribution to journalArticle

Osteoblasts
Durapatite
Hydroxyapatite
Magnetron sputtering
Coatings
2006

Glucocorticoid-induced osteoporosis

Dempster, DW. & Stern, PH., 2006, In : National Osteoporosis Foundation Update.

Research output: Contribution to journalArticle

56 Citations (Scopus)

Reveromycin A, an agent for osteoporosis, inhibits bone resorption by inducing apoptosis specifically in osteoclasts

Woo, J. T., Kawatani, M., Kato, M., Shinki, T., Yonezawa, T., Kanoh, N., Nakagawa, H., Takami, M., Lee, K. H., Stern, P. H., Nagai, K. & Osada, H., Mar 21 2006, In : Proceedings of the National Academy of Sciences of the United States of America. 103, 12, p. 4729-4734 6 p.

Research output: Contribution to journalArticle

Osteoclasts
Bone Resorption
Osteoporosis
Apoptosis
Isoleucine-tRNA Ligase
2005
66 Citations (Scopus)

12/Gα13 subunits of heterotrimeric G proteins mediate parathyroid hormone activation of phospholipase D in UMR-106 osteoblastic cells

Singh, A., Gilchrist, A., Voyno-Yasenetskaya, T., Radeff-Huang, J. M. & Stern, P. H., May 1 2005, In : Endocrinology. 146, 5, p. 2171-2175 5 p.

Research output: Contribution to journalArticle

G12-G13 GTP-Binding Protein alpha Subunits
Heterotrimeric GTP-Binding Proteins
Phospholipase D
Parathyroid Hormone
Anabolic Agents
33 Citations (Scopus)

Inhibitory effects of mevastatin and a geranylgeranyl transferase I inhibitor (GGTI-2166) on mononuclear osteoclast formation induced by receptor activator of NFκB ligand (RANKL) or tumor necrosis factor-α (TNF-α)

Woo, J. T., Nakagawa, H., Krecic, A. M., Nagai, K., Hamilton, A. D., Sebti, S. M. & Stern, P. H., Jan 1 2005, In : Biochemical Pharmacology. 69, 1, p. 87-95 9 p.

Research output: Contribution to journalArticle

Protein Prenylation
Osteoclasts
Transferases
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Tumor Necrosis Factor-alpha
7 Citations (Scopus)

Parathyroid hormone stimulates phosphatidylethanolamine hydrolysis by phospholipase D in osteoblastic cells

Singh, A., Frohman, M. A. & Stern, P. H., Nov 1 2005, In : Lipids. 40, 11, p. 1135-1140 6 p., L9504.

Research output: Contribution to journalArticle

Phorbol 12,13-Dibutyrate
Phospholipase D
phospholipase D
Ethanolamine
parathyroid hormone
10 Citations (Scopus)
Calcitriol
Parathyroid Hormone
Colforsin
Ligands
Immunoenzyme Techniques
2004
20 Citations (Scopus)

Bone anabolic responses to mechanical load in vitro involve COX-2 constitutive NOS

Kunnel, J. G., Igarashi, K., Gilbert, J. L. & Stern, P. H., Apr 27 2004, In : Connective Tissue Research. 45, 1, p. 40-49 10 p.

Research output: Contribution to journalArticle

Cyclooxygenase 2
Nitric Oxide Synthase
Bone
Bone and Bones
Protein Isoforms
37 Citations (Scopus)

Cyclosporine A and FK506 induce osteoclast apoptosis in mouse bone marrow cell cultures

Igarashi, K., Hirotani, H., Woo, J. T. & Stern, P. H., Jul 1 2004, In : Bone. 35, 1, p. 47-56 10 p.

Research output: Contribution to journalArticle

Tacrolimus
Osteoclasts
Bone Marrow Cells
Cyclosporine
Cell Culture Techniques
23 Citations (Scopus)

MicroCT quantification of in vitro bone resorption of neonatal murine calvaria exposed to IL-1 or PTH

Stock, S. R., Ignatiev, K. I., Foster, S. A., Forman, L. A. & Stern, P. H., Aug 1 2004, In : Journal of Structural Biology. 147, 2, p. 185-199 15 p.

Research output: Contribution to journalArticle

X-Ray Microtomography
Bone Resorption
Parathyroid Hormone
Interleukin-1
Skull
154 Citations (Scopus)

Osteoporosis in chronic kidney disease

Cunningham, J., Sprague, SM., Cannata-Andia, J., Coco, M., Cohen-Solal, M., Fitzpatrick, L., Goltzmann, D., Lafage-Proust, MH., Leonard, M., Ott, S., Rodriguez, M., Stehman-Breen, C., Stern, P., Weisinger, J. & Group, O. W., 2004, In : Am J Kidney Disease. 43, 3, p. 566-571 6 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)
rho-Associated Kinases
Parathyroid Hormone
Protein Kinase C
Interleukin-6
Monomeric GTP-Binding Proteins
28 Citations (Scopus)
Parathyroid Hormone Receptor Type 1
Phospholipase D
Type C Phospholipases
Cyclic AMP-Dependent Protein Kinases
Parathyroid Hormone
197 Citations (Scopus)

The Calcineurin/Nuclear Factor of Activated T Cells Signaling Pathway Regulates Osteoclastogenesis in RAW264.7 Cells

Hirotani, H., Tuohy, N. A., Woo, J. T., Stern, P. H. & Clipstone, N. A., Apr 2 2004, In : Journal of Biological Chemistry. 279, 14, p. 13984-13992 9 p.

Research output: Contribution to journalArticle

NFATC Transcription Factors
Cell signaling
Calcineurin
Osteoclasts
Osteogenesis
2003

Glucocorticoid-induced osteoporosis

Dempster, DW. & Stern, PH., 2003, In : National Osteoporosis Foundation Osteoporosis Update.

Research output: Contribution to journalArticle

8 Citations (Scopus)
Cell proliferation
Conditioned Culture Medium
Insulin-Like Growth Factor I
Prostatic Neoplasms
Phosphotransferases
16 Citations (Scopus)

Regulation of parathyroid hormone-stimulated phospholipase D in UMR-106 cells by calcium, MAP kinase, and small G proteins

Singh, A., Bhattacharyya, R. S., Radeff, J. M. & Stern, P. H., Aug 1 2003, In : Journal of Bone and Mineral Research. 18, 8, p. 1453-1460 8 p.

Research output: Contribution to journalArticle

Phospholipase D
Monomeric GTP-Binding Proteins
Parathyroid Hormone
Phosphotransferases
Phorbol 12,13-Dibutyrate
2002
37 Citations (Scopus)

Effects of a selective cyclooxygenase-2 inhibitor, celecoxib, on bone resorption and osteoclastogenesis in vitro

Igarashi, K., Woo, J. T. & Stern, P. H., Feb 1 2002, In : Biochemical Pharmacology. 63, 3, p. 523-532 10 p.

Research output: Contribution to journalArticle

Celecoxib
Cyclooxygenase 2 Inhibitors
Bone Resorption
Osteogenesis
Bone
10 Citations (Scopus)

In Vitro mechanical and cellular responses of neonatal mouse bones to loading using a novel micromechanical-testing device

Kunnel, J. G., Gilbert, J. L. & Stern, P. H., Dec 1 2002, In : Calcified Tissue International. 71, 6, p. 499-507 9 p.

Research output: Contribution to journalArticle

Bone and Bones
Equipment and Supplies
In Vitro Techniques
Autoradiography
Tibia
2001
33 Citations (Scopus)

Involvement of PKC-β in PTH, TNF-α, and IL-1β effects on IL-6 promoter in osteoblastic cells and on PTH-stimulated bone resorption

Radeff, J. M., Nagy, Z. & Stern, P. H., Aug 15 2001, In : Experimental Cell Research. 268, 2, p. 179-188 10 p.

Research output: Contribution to journalArticle

5,21 - 12,17-dimetheneo-18H-dibenzo(i,o)pyrrolo(3,4-1)(1,8)diazacyclohexandecine-18,10(19H)dione,8((dimethylamino)methyl)-6,7,8,9,10,11-hexahydro,monomethanesulfonate
Bone Resorption
Parathyroid Hormone
Interleukin-1
Protein Kinase C
21 Citations (Scopus)

Mutual up-regulation of thyroid hormone and parathyroid hormone receptors in rat osteoblastic osteosarcoma 17/2.8 cells

Gu, W. X., Stern, P. H., Madison, L. D. & Du, G. G., Jan 1 2001, In : Endocrinology. 142, 1, p. 157-164 8 p.

Research output: Contribution to journalArticle

Parathyroid Hormone Receptors
Parathyroid Hormone Receptor Type 1
Osteosarcoma
Thyroid Hormones
Parathyroid Hormone-Related Protein
16 Citations (Scopus)

Parathyroid hormone stimulates translocation of protein kinase C isozymes in UMR-106 osteoblastic osteosarcoma cells

Dossing, D. A., Radeff, J. M., Sanders, J., Lee, S. K., Hsieh, M. R. & Stern, P. H., Sep 17 2001, In : Bone. 29, 3, p. 223-230 8 p.

Research output: Contribution to journalArticle

Osteosarcoma
Parathyroid Hormone
Protein Kinase C
Isoenzymes
Phorbol 12,13-Dibutyrate
26 Citations (Scopus)
Parathyroid Hormone
Interleukin-1
Protein Kinase C
Interleukin-6
Tumor Necrosis Factor-alpha
2000
73 Citations (Scopus)

Compactin suppresses bone resorption by inhibiting the fusion of prefusion osteoclasts and disrupting the actin ring in osteoclasts

Woo, J. T., Kasai, S., Stern, P. H. & Nagai, K., Apr 7 2000, In : Journal of Bone and Mineral Research. 15, 4, p. 650-662 13 p.

Research output: Contribution to journalArticle

Osteoclasts
Bone Resorption
Actins
Protein Prenylation
mevastatin
9 Citations (Scopus)
Staurosporine
Protein C Inhibitor
Protein Kinase Inhibitors
Bone Resorption
Protein Kinase C
8 Citations (Scopus)

Endothelin-stimulated Ca2+ signaling and endothelin receptor expression are decreased by parathyroid hormone treatment in UMR-106 osteoblastic osteosarcoma cells

Semler, D. E., Morris, D. L. & Stern, P. H., Jan 1 2000, In : Cell Calcium. 28, 1, p. 55-64 10 p.

Research output: Contribution to journalArticle

Endothelin Receptors
Endothelins
Osteosarcoma
Parathyroid Hormone
Parathyroid Hormone Receptor Type 1
56 Citations (Scopus)

Insulin-like growth factor I production is essential for anabolic effects of thyroid hormone in osteoblasts

Huang, B. K., Golden, L. A., Tarjan, G., Madison, L. D. & Stern, P. H., Feb 24 2000, In : Journal of Bone and Mineral Research. 15, 2, p. 188-197 10 p.

Research output: Contribution to journalArticle

Anabolic Agents
Osteoblasts
Insulin-Like Growth Factor I
Thyroid Hormones
IGF Type 1 Receptor
17 Citations (Scopus)
Phospholipase D
Osteosarcoma
Phosphatidylcholines
Hydrolysis
Type C Phospholipases
29 Citations (Scopus)
Parathyroid Hormone
Protein Kinase C
Interleukin-6
Tumor Necrosis Factor-alpha
Isoenzymes
35 Citations (Scopus)

Serum insulin-like growth factor-I, insulin-like growth factor binding proteins, and bone mineral content in hyperthyroidism

Lakatos, P., Foldes, J., Nagy, Z., Takacs, I., Speer, G., Horvath, C., Mohan, S., Baylink, D. J. & Stern, P. H., Jan 1 2000, In : Thyroid. 10, 5, p. 417-423 7 p.

Research output: Contribution to journalArticle

Insulin-Like Growth Factor Binding Proteins
Hyperthyroidism
Insulin-Like Growth Factor I
Bone Density
Insulin-Like Growth Factor Binding Protein 4
1999
34 Citations (Scopus)
Phorbol 12,13-Dibutyrate
Parathyroid Hormone-Related Protein
Parathyroid Hormone
Phosphatidylcholines
Amides
2 Citations (Scopus)

Staurosporine enhances parathyroid hormone-induced calcium signal in UMR-106 osteoblastic cells

Lee, S. K. & Stern, P. H., Jan 1 1999, In : Archives of Pharmacal Research. 22, 2, p. 119-123 5 p.

Research output: Contribution to journalArticle

Staurosporine
Parathyroid Hormone
Calcium
Phorbol Esters
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine
1998
22 Citations (Scopus)
Alendronate
Interleukin-1
Interleukin-6
Bone and Bones
Bone Resorption