Grants per year
Personal profile
Research Interests
I am interested in understanding the cellular and molecular mechanisms for cell-type specific degeneration in neurodegenerative diseases. I am mainly focused on corticospinal motor neurons that degenerate in ALS, and HSP.
Education/Academic qualification
PhD, Louisiana State University
… → 2002
Research interests
- Neurology
- Neuroscience
- Neurosurgery
Fingerprint Dive into the research topics where Pembe Hande Ozdinler is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 11 Similar Profiles
Motor Neurons
Medicine & Life Sciences
Amyotrophic Lateral Sclerosis
Medicine & Life Sciences
Axons
Medicine & Life Sciences
Neurons
Medicine & Life Sciences
Ubiquitin Thiolesterase
Medicine & Life Sciences
Motor Neuron Disease
Medicine & Life Sciences
Dendrites
Medicine & Life Sciences
Motor Cortex
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Grants 2006 2024
Investigation and Confirmation of Novel Targets by Utilization of Proteomics
Mitsubishi Tanabe Pharma Corporation
10/1/19 → 9/30/20
Project: Research project
Motor Neurons
Proteomics
Proteins
Health
Therapeutics
Novel Protein Aggregation Inhibitors and Upper Motor Neuron Stabilizers for ALS and other Neurodegenerative Diseases
Ozdinler, P. H. & Silverman, R. B.
8/1/19 → 4/30/24
Project: Research project
Amyotrophic Lateral Sclerosis
Motor Neurons
Neurodegenerative Diseases
Motor Neuron Disease
Drug Discovery
SRA: Preclinical Investigation of SBT Discovery Compounds in Upper Motor Neuron Cell Based Model of ALS
8/1/19 → 8/1/22
Project: Research project
Motor Neurons
Transgenes
Primary Cell Culture
Neuroprotective Agents
Endoplasmic Reticulum
The Role of Mitochondria in TDP-43 Proteinopathy
Fushimi, K., Kiskinis, E., Ozdinler, P. H. & Wu, J.
National Institute of Neurological Disorders and Stroke
9/30/18 → 6/30/23
Project: Research project
TDP-43 Proteinopathies
Mitochondria
Frontotemporal Dementia
Neurodegenerative Diseases
Frontotemporal Lobar Degeneration
Northwestern University Interdepartmental Neuroscience Postbaccalaureate Research Education Program
Acosta, A., Allada, R., Apkarian, A., Awatramani, R., Beeman, M., Bevan, M. D., Bozza, T. C., Cang, J., Chetkovich, D. M., Cobia, D. J., Contractor, A., Corcos, D. M., DeVries, S. H., Dewald, J. P. A., Dhar, S., Disterhoft, J. F., Dombeck, D. A., Elliott, J. M., Feng, Y., Ferreira, A. B., Gallio, M., Garcia-Anoveros, J., George Jr, A. L., Geula, C., Gordon, K. E., Gottfried, J. A., Grafman, J. H., Hartmann, M. J. Z., Heckman, C., Hespos, S. J., Jayaraman, A., Kahnt, T., Kearney, J. A., Kessler, J., Kiskinis, E., Kohtz, J., Kording, K. P., Kozorovitskiy, Y., Krainc, D., Larson, C., Lee, S. S. M., Li, L., Losh, M. C., Maccaferri, G., MacIver, M. A., Martina, M., Mazzulli, J., McLean, D., Mesulam, M., Miller, L. E., Miller, R. J., Mussa-Ivaldi, F., Nusslock, R., Opal, P., Ozdinler, P. H., Paller, K., Parrish, T. B., Prakriya, M., Radulovic, J., Raman, I. M., Reber, P. J., Redei, E., Rogalski, E., Sanchez, J. T., Sanz-Clemente, A., Savas, J. N., Schmidt, T. M., Schwartz, G. W., Segraves, M., Shepherd, G. M. G., Siddique, T., Solla, S. A., Surmeier Jr, D. J., Swanson, G. T., Topczewski, J., Tresch, M. C., Tysseling, V. M., Vassar, R. J., Voss, J. L., Wainwright, D. A., Wang, L., Weintraub, S., Woolley, C. S. & Wright, B. A.
National Institute of General Medical Sciences
5/1/17 → 4/30/22
Project: Research project
neurosciences
graduate
university
education
Research Output 1999 2018
3
Citations
(Scopus)
Incorporating upper motor neuron health in ALS drug discovery
Dervishi, I. & Ozdinler, P. H., Mar 1 2018, In : Drug Discovery Today. 23, 3, p. 696-703 8 p.Research output: Contribution to journal › Review article
Amyotrophic Lateral Sclerosis
Motor Neurons
Drug Discovery
Health
Clinical Trials
2
Citations
(Scopus)
Protein-protein interactions reveal key canonical pathways, upstream regulators, interactome domains, and novel targets in ALS
Dervishi, I., Gozutok, O., Murnan, K., Gautam, M., Heller, D., Bigio, E. H. & Ozdinler, P. H., Dec 1 2018, In : Scientific reports. 8, 1, 14732.Research output: Contribution to journal › Article
Amyotrophic Lateral Sclerosis
Proteins
14-3-3 Proteins
Mutation
Neurodegenerative Diseases
Apical dendrite degeneration, a novel cellular pathology for Betz cells in ALS
Genc, B., Jara, JH., Lagrimas, AK., Pytel, P., Roo, RP., Mesulam, MM., Geula, C., Bigio, EH. & Ozdinler, PH., Feb 2017, In : Scientific Reports.Research output: Contribution to journal › Article
15
Citations
(Scopus)
Apical dendrite degeneration, a novel cellular pathology for Betz cells in ALS
Genç, B., Jara, J. H., Lagrimas, A. K. B., Pytel, P., Roos, R. P., Mesulam, M-M., Geula, C., Bigio, E. H. & Ozdinler, P. H., Feb 6 2017, In : Scientific reports. 7, 41765.Research output: Contribution to journal › Article
Dendrites
Pathology
Motor Cortex
Alzheimer Disease
Frontotemporal Dementia
3
Citations
(Scopus)
Evidence for an early innate immune response in the motor cortex of ALS
Jara, J. H., Genç, B., Stanford, M. J., Pytel, P., Roos, R. P., Weintraub, S., Mesulam, M-M., Bigio, E. H., Miller, R. J. & Ozdinler, P. H., Jun 26 2017, In : Journal of Neuroinflammation. 14, 1, 129.Research output: Contribution to journal › Article
Amyotrophic Lateral Sclerosis
Motor Cortex
Chemokine CCL2
CCR2 Receptors
Innate Immunity