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Pembe Hande Ozdinler

  • 3693 Citations
19992020

Research output per year

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Personal profile

Research Interests

I am interested in understanding the cellular and molecular mechanisms for cell-type specific degeneration in neurodegenerative diseases. I am mainly focused on corticospinal motor neurons that degenerate in ALS, and HSP.

Education/Academic qualification

PhD, Louisiana State University

… → 2002

Research interests

  • Neurology
  • Neuroscience
  • Neurosurgery

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Grants

Investigation and assessment of UCHL1 as a novel target

Ozdinler, P. H.

Mitsubishi Tanabe Pharma Holdings America, Inc.

12/19/19 → 12/19/20

Project: Research project

    • Investigation and Confirmation of Novel Targets by Utilization of Proteomics

    Ozdinler, P. H.

    Mitsubishi Tanabe Pharma Corporation

    10/1/19 → 9/30/20

    Project: Research project

    • SRA: Preclinical Investigation of SBT Discovery Compounds in Upper Motor Neuron Cell Based Model of ALS

    Ozdinler, P. H.

    Stealth BioTherapeutics Inc.

    8/1/19 → 8/1/22

    Project: Research project

    • Novel Protein Aggregation Inhibitors and Upper Motor Neuron Stabilizers for ALS and other Neurodegenerative Diseases

    Ozdinler, P. H. & Silverman, R. B.

    National Institute on Aging

    8/1/19 → 4/30/24

    Project: Research project

    • The Role of Mitochondria in TDP-43 Proteinopathy

    Fushimi, K., Kiskinis, E., Ozdinler, P. H. & Wu, J.

    National Institute of Neurological Disorders and Stroke

    9/30/18 → 6/30/23

    Project: Research project

    • Research Output

    • 3693 Citations
    • 29 Article
    • 5 Review article
    • 1 Chapter
    • 1 Comment/debate

    The Electrophysiological Determinants of Corticospinal Motor Neuron Vulnerability in ALS

    Jara, J. H., Sheets, P. L., Nigro, M. J., Perić, M., Brooks, C., Heller, D. B., Martina, M., Andjus, P. R. & Ozdinler, P. H., May 19 2020, In : Frontiers in Molecular Neuroscience. 13, 73.

    Research output: Contribution to journal › Article

    Open Access

    • Complexity of generating mouse models to study the upper motor neurons: Let us shift focus from mice to neurons

    Genc, B., Gozutok, O. & Hande Ozdinler, P., Aug 2 2019, In : International journal of molecular sciences. 20, 16, 3848.

    Research output: Contribution to journal › Review article

    Open Access

    • MCP1-CCR2 and neuroinflammation in the ALS motor cortex with TDP-43 pathology

    Jara, J. H., Gautam, M., Kocak, N., Xie, E. F., Mao, Q., Bigio, E. H. & Özdinler, P. H., Oct 30 2019, In : Journal of neuroinflammation. 16, 1, 1 p.

    Research output: Contribution to journal › Article

    Open Access
    • 3 Scopus citations

    Mitoautophagy: A Unique Self-Destructive Path Mitochondria of Upper Motor Neurons With TDP-43 Pathology Take, Very Early in ALS

    Gautam, M., Xie, E. F., Kocak, N. & Ozdinler, P. H., Nov 7 2019, In : Frontiers in Cellular Neuroscience. 13, 489.

    Research output: Contribution to journal › Article

    Open Access
    • 1 Scopus citations

    Incorporating upper motor neuron health in ALS drug discovery

    Dervishi, I. & Ozdinler, P. H., Mar 2018, In : Drug Discovery Today. 23, 3, p. 696-703 8 p.

    Research output: Contribution to journal › Review article

    • 4 Scopus citations