Pembe Hande Ozdinler

Phone312/503-2774
Emailozdinler@northwestern.edu

Source: Scopus

Research output per year

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Personal profile

Research Interests

I am interested in understanding the cellular and molecular mechanisms for cell-type specific degeneration in neurodegenerative diseases. I am mainly focused on corticospinal motor neurons that degenerate in ALS, and HSP.

Education/Academic qualification

PhD, Louisiana State University

… → 2002

Research interests

Neurology
Neuroscience
Neurosurgery

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7 Active
15 Finished

Directed Gene Delivery to Upper Motor Neurons
Ozdinler, P. H.
Spastic Paraplegia Foundation, Inc.
7/16/20 → 7/15/22
Project: Research project
Investigation and assessment of UCHL1 as a novel target
Ozdinler, P. H.
Mitsubishi Tanabe Pharma Holdings America, Inc.
12/19/19 → 12/19/20
Project: Research project
Investigation and Confirmation of Novel Targets by Utilization of Proteomics
Ozdinler, P. H.
Mitsubishi Tanabe Pharma Corporation
10/1/19 → 9/30/20
Project: Research project
SRA: Preclinical Investigation of SBT Discovery Compounds in Upper Motor Neuron Cell Based Model of ALS
Ozdinler, P. H.
Stealth BioTherapeutics Inc.
8/1/19 → 8/1/22
Project: Research project
Novel Protein Aggregation Inhibitors and Upper Motor Neuron Stabilizers for ALS and other Neurodegenerative Diseases
Ozdinler, P. H. & Silverman, R. B.
National Institute on Aging
8/1/19 → 4/30/24
Project: Research project

4146 Citations
30 Article
5 Review article
1 Chapter
1 Comment/debate

Help from peripheral macrophages in ALS?
Özdinler, P. H., Nov 1 2020, In: Nature neuroscience. 23, 11, p. 1311-1312 2 p.
Research output: Contribution to journal › Article › peer-review
The Electrophysiological Determinants of Corticospinal Motor Neuron Vulnerability in ALS
Jara, J. H., Sheets, P. L., Nigro, M. J., Perić, M., Brooks, C., Heller, D. B., Martina, M., Andjus, P. R. & Ozdinler, P. H., May 19 2020, In: Frontiers in Molecular Neuroscience. 13, 73.
Research output: Contribution to journal › Article › peer-review

Open Access
1 Scopus citations
Complexity of generating mouse models to study the upper motor neurons: Let us shift focus from mice to neurons
Genc, B., Gozutok, O. & Hande Ozdinler, P., Aug 2 2019, In: International journal of molecular sciences. 20, 16, 3848.
Research output: Contribution to journal › Review article › peer-review

Open Access
3 Scopus citations
MCP1-CCR2 and neuroinflammation in the ALS motor cortex with TDP-43 pathology
Jara, J. H., Gautam, M., Kocak, N., Xie, E. F., Mao, Q., Bigio, E. H. & Özdinler, P. H., Oct 30 2019, In: Journal of neuroinflammation. 16, 1, p. 196 1 p.
Research output: Contribution to journal › Article › peer-review

Open Access
5 Scopus citations
Mitoautophagy: A Unique Self-Destructive Path Mitochondria of Upper Motor Neurons With TDP-43 Pathology Take, Very Early in ALS
Gautam, M., Xie, E. F., Kocak, N. & Ozdinler, P. H., Nov 7 2019, In: Frontiers in Cellular Neuroscience. 13, 489.
Research output: Contribution to journal › Article › peer-review

Open Access
4 Scopus citations