Grants per year
Personal profile
Research Interests
I am interested in understanding the cellular and molecular mechanisms for cell-type specific degeneration in neurodegenerative diseases. I am mainly focused on corticospinal motor neurons that degenerate in ALS, and HSP.
Education/Academic qualification
PhD, Louisiana State University
… → 2002
Research interests
- Neurology
- Neuroscience
- Neurosurgery
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Network
Grants
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Directed Gene Delivery to Upper Motor Neurons
Spastic Paraplegia Foundation, Inc.
7/16/20 → 7/15/22
Project: Research project
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Investigation and assessment of UCHL1 as a novel target
Mitsubishi Tanabe Pharma Holdings America, Inc.
12/19/19 → 12/19/20
Project: Research project
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Investigation and Confirmation of Novel Targets by Utilization of Proteomics
Mitsubishi Tanabe Pharma Corporation
10/1/19 → 9/30/20
Project: Research project
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SRA: Preclinical Investigation of SBT Discovery Compounds in Upper Motor Neuron Cell Based Model of ALS
8/1/19 → 8/1/22
Project: Research project
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Novel Protein Aggregation Inhibitors and Upper Motor Neuron Stabilizers for ALS and other Neurodegenerative Diseases
Ozdinler, P. H. & Silverman, R. B.
8/1/19 → 4/30/24
Project: Research project
Research Output
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Help from peripheral macrophages in ALS?
Özdinler, P. H., Nov 1 2020, In: Nature neuroscience. 23, 11, p. 1311-1312 2 p.Research output: Contribution to journal › Article › peer-review
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The Electrophysiological Determinants of Corticospinal Motor Neuron Vulnerability in ALS
Jara, J. H., Sheets, P. L., Nigro, M. J., Perić, M., Brooks, C., Heller, D. B., Martina, M., Andjus, P. R. & Ozdinler, P. H., May 19 2020, In: Frontiers in Molecular Neuroscience. 13, 73.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Complexity of generating mouse models to study the upper motor neurons: Let us shift focus from mice to neurons
Genc, B., Gozutok, O. & Hande Ozdinler, P., Aug 2 2019, In: International journal of molecular sciences. 20, 16, 3848.Research output: Contribution to journal › Review article › peer-review
Open Access3 Scopus citations -
MCP1-CCR2 and neuroinflammation in the ALS motor cortex with TDP-43 pathology
Jara, J. H., Gautam, M., Kocak, N., Xie, E. F., Mao, Q., Bigio, E. H. & Özdinler, P. H., Oct 30 2019, In: Journal of neuroinflammation. 16, 1, p. 196 1 p.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Mitoautophagy: A Unique Self-Destructive Path Mitochondria of Upper Motor Neurons With TDP-43 Pathology Take, Very Early in ALS
Gautam, M., Xie, E. F., Kocak, N. & Ozdinler, P. H., Nov 7 2019, In: Frontiers in Cellular Neuroscience. 13, 489.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations