• 970 Citations
20042020

Research output per year

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Personal profile

Research Interests

The research in my laboratory focuses on the studies of normal hematopoiesis and myeloid malignancies. Major research areas include: 1) Mechanistic studies of chromatin condensation during erythropoiesis under steady state and stress/disease conditions. 2) Studies of mDia formin proteins in homing and migration of hematopoietic stem cells, as well as the role of mDia1 in the pathogenesis of myelodysplastic syndromes. 3) The role of Pleckstrin-2 (Plek2) in normal erythropoiesis and red cell related diseases. We use molecular and cell biology techniques and mouse genetics in many of these studies.

Training Experience

2010Fellowship, Whitehead Institute for Biomedical Research
2013Residency, Northwestern University, McGaw Medical Center (Northwestern Memorial Hospital)

Education/Academic qualification

PhD, Albert Einstein College

… → 2006

MD, Peking University

… → 2000

Research interests

  • Blood Cancer (leukemia and lymphomas)
  • Cell Biology
  • Cytoskeleton
  • Developmental Biology
  • Genetics
  • Stem Cells
  • Transplantation

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Grants

  • Research Output

    Atypical lymphocytes in peripheral blood of patients with COVID-19

    Weinberg, S. E., Behdad, A. & Ji, P., Jul 1 2020, In : British Journal of Haematology. 190, 1, p. 36-39 4 p.

    Research output: Contribution to journalLetter

    Open Access
  • 2 Scopus citations

    Diaphanous-related formin mDia2 regulates beta2 integrins to control hematopoietic stem and progenitor cell engraftment

    Mei, Y., Han, X., Liu, Y., Yang, J., Sumagin, R. & Ji, P., Dec 1 2020, In : Nature communications. 11, 1, 3172.

    Research output: Contribution to journalArticle

    Open Access
  • FOXM1 regulates leukemia stem cell quiescence and survival in MLL-rearranged AML

    Sheng, Y., Yu, C., Liu, Y., Hu, C., Ma, R., Lu, X., Ji, P., Chen, J., Mizukawa, B., Huang, Y., Licht, J. D. & Qian, Z., Dec 1 2020, In : Nature communications. 11, 1, 928.

    Research output: Contribution to journalArticle

    Open Access
  • Aurora kinase A inhibition provides clinical benefit, normalizes megakaryocytes, and reduces bone marrow fibrosis in patients with myelofibrosis: A phase I trial

    Gangat, N., Marinaccio, C., Swords, R., Watts, J. M., Gurbuxani, S., Rademaker, A., Fought, A. J., Frankfurt, O., Altman, J. K., Wen, Q. J., Farnoud, N., Famulare, C. A., Patel, A., Tapia, R., Vallapureddy, R. R., Barath, S., Graf, A., Handlogten, A., Zblewski, D., Patnaik, M. M. & 14 others, Al-Kali, A., Dinh, Y. T., Prahl, K. E., Patel, S., Nobrega, J. C., Tejera, D., Thomassen, A., Gao, J., Ji, P., Rampal, R. K., Giles, F. J., Tefferi, A., Stein, B. & Crispino, J. D., Aug 15 2019, In : Clinical Cancer Research. 25, 16, p. 4898-4906 9 p.

    Research output: Contribution to journalArticle

  • 16 Scopus citations

    Cytokine-regulated phosphorylation and activation of TET2 by JAK2 in hematopoiesis

    Jeong, J. J., Gu, X., Nie, J., Sundaravel, S., Liu, H., Kuo, W. L., Bhagat, T. D., Pradhan, K., Cao, J., Nischal, S., McGraw, K. L., Bhattacharyya, S., Bishop, M. R., Artz, A., Thirman, M. J., Moliterno, A., Ji, P., Levine, R. L., Godley, L. A., Steidl, U. & 6 others, Bieker, J. J., List, A. F., Saunthararajah, Y., He, C., Verma, A. & Wickrema, A., Jun 2019, In : Cancer discovery. 9, 6, p. 778-795 18 p.

    Research output: Contribution to journalArticle

    Open Access
  • 5 Scopus citations