Peter F Whitington

  • 14445 Citations
1976 …2019
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Personal profile

Research Interests

Dr. Whitington's research involves the study of immune mechanisms of pediatric liver diseases. Our lab has identified an alloimmune mechanism of fetal liver injury, a process we call gestational alloimmune liver disease, which is the cause of most or all cases of neonatal hemochromatosis and is the likely cause of most cases of liver failure in the first 3 months of life. We also suspect it to be a major cause of intrauterine fetal demise. We are also investigating the immune mechanisms of biliary atresia.

Certifications and Licenses

Pediatric Transplant Hepatology
Pediatrics
Pediatric Gastroenterology

Training Experience

1974Residency, Univ. of Tennessee-Health Services
1977Fellowship, Johns Hopkins Hospital
1978Fellowship, University of Wisconsin Hospital & Clinics

Education/Academic qualification

MD, University of Tennessee

… → 1971

Research interests

  • Autoimmune Diseases
  • Digestive System (including gallbladder and liver)
  • Immune System
  • Pediatrics
  • Transplantation

Fingerprint Dive into the research topics where Peter F Whitington is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 17 Similar Profiles
Liver Transplantation Medicine & Life Sciences
Liver Medicine & Life Sciences
Pediatrics Medicine & Life Sciences
Biliary Atresia Medicine & Life Sciences
Liver Diseases Medicine & Life Sciences
Bilirubin Medicine & Life Sciences
Transplants Medicine & Life Sciences
Living Donors Medicine & Life Sciences

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Grants 2012 2019

Research Output 1976 2019

Oligoclonal immunoglobulin repertoire in biliary remnants of biliary atresia

Taylor, S. A., Malladi, P., Pan, X., Wechsler, J. B., Hulse, K. E., Perlman, H. R. & Whitington, P. F., Dec 1 2019, In : Scientific reports. 9, 1, 4508.

Research output: Contribution to journalArticle

Open Access
Oligoclonal Bands
Biliary Atresia
Immunoglobulins
Liver Diseases
B-Lymphocytes
2 Citations (Scopus)

Antenatal Treatment with Intravenous Immunoglobulin to Prevent Gestational Alloimmune Liver Disease: Comparative Effectiveness of 14-Week versus 18-Week Initiation

Whitington, P. F., Kelly, S., Taylor, S. A., Nóbrega, S., Schreiber, R. A., Sokal, E. M. & Hibbard, J. U., Apr 1 2018, In : Fetal Diagnosis and Therapy. 43, 3, p. 218-225 8 p.

Research output: Contribution to journalArticle

Intravenous Immunoglobulins
Liver Diseases
Pregnancy Outcome
Pregnancy
Therapeutics
3 Citations (Scopus)

Clinically Actionable Hypercholesterolemia and Hypertriglyceridemia in Children with Nonalcoholic Fatty Liver Disease

Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN), Jul 1 2018, In : Journal of Pediatrics. 198, p. 76-83.e2

Research output: Contribution to journalArticle

Hypertriglyceridemia
Hypercholesterolemia
Lipids
Dyslipidemias
LDL Cholesterol
1 Citation (Scopus)
Portal Vein
Histology
Thrombosis
Liver
Fibrosis
16 Citations (Scopus)

In Children With Nonalcoholic Fatty Liver Disease, Zone 1 Steatosis Is Associated With Advanced Fibrosis

Africa, J. A., Behling, C. A., Brunt, E. M., Zhang, N., Luo, Y., Wells, A., Hou, J., Belt, P. H., Kohil, R., Lavine, J. E., Molleston, J. P., Newton, K. P., Whitington, P. F. & Schwimmer, J. B., Mar 1 2018, In : Clinical Gastroenterology and Hepatology. 16, 3, p. 438-446.e1

Research output: Contribution to journalArticle

Fibrosis
Fatty Liver
Pediatrics
Non-alcoholic Fatty Liver Disease
Natural History