Peter F Whitington

  • 14983 Citations
1976 …2019

Research output per year

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Personal profile

Research Interests

Dr. Whitington's research involves the study of immune mechanisms of pediatric liver diseases. Our lab has identified an alloimmune mechanism of fetal liver injury, a process we call gestational alloimmune liver disease, which is the cause of most or all cases of neonatal hemochromatosis and is the likely cause of most cases of liver failure in the first 3 months of life. We also suspect it to be a major cause of intrauterine fetal demise. We are also investigating the immune mechanisms of biliary atresia.

Certifications and Licenses

Pediatric Transplant Hepatology
Pediatric Gastroenterology

Training Experience

1974Residency, Univ. of Tennessee-Health Services
1977Fellowship, Johns Hopkins Hospital
1978Fellowship, University of Wisconsin Hospital & Clinics

Education/Academic qualification

MD, University of Tennessee, Knoxville

… → 1971

Research interests

  • Autoimmune Diseases
  • Digestive System (including gallbladder and liver)
  • Immune System
  • Pediatrics
  • Transplantation

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Research Output

Oligoclonal immunoglobulin repertoire in biliary remnants of biliary atresia

Taylor, S. A., Malladi, P., Pan, X., Wechsler, J. B., Hulse, K. E., Perlman, H. R. & Whitington, P. F., Dec 1 2019, In : Scientific reports. 9, 1, 4508.

Research output: Contribution to journalArticle

Open Access
  • Antenatal Treatment with Intravenous Immunoglobulin to Prevent Gestational Alloimmune Liver Disease: Comparative Effectiveness of 14-Week versus 18-Week Initiation

    Whitington, P. F., Kelly, S., Taylor, S. A., Nóbrega, S., Schreiber, R. A., Sokal, E. M. & Hibbard, J. U., Apr 1 2018, In : Fetal Diagnosis and Therapy. 43, 3, p. 218-225 8 p.

    Research output: Contribution to journalArticle

  • 5 Scopus citations

    Clinically Actionable Hypercholesterolemia and Hypertriglyceridemia in Children with Nonalcoholic Fatty Liver Disease

    Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN), Jul 2018, In : Journal of Pediatrics. 198, p. 76-83.e2

    Research output: Contribution to journalArticle

  • 5 Scopus citations
  • 1 Scopus citations

    In Children With Nonalcoholic Fatty Liver Disease, Zone 1 Steatosis Is Associated With Advanced Fibrosis

    Africa, J. A., Behling, C. A., Brunt, E. M., Zhang, N., Luo, Y., Wells, A., Hou, J., Belt, P. H., Kohil, R., Lavine, J. E., Molleston, J. P., Newton, K. P., Whitington, P. F. & Schwimmer, J. B., Mar 1 2018, In : Clinical Gastroenterology and Hepatology. 16, 3, p. 438-446.e1

    Research output: Contribution to journalArticle

  • 22 Scopus citations