Grants per year
Personal profile
Research Interests
Dr. Whitington's research involves the study of immune mechanisms of pediatric liver diseases. Our lab has identified an alloimmune mechanism of fetal liver injury, a process we call gestational alloimmune liver disease, which is the cause of most or all cases of neonatal hemochromatosis and is the likely cause of most cases of liver failure in the first 3 months of life. We also suspect it to be a major cause of intrauterine fetal demise. We are also investigating the immune mechanisms of biliary atresia.
Certifications and Licenses
| Pediatric Transplant Hepatology | |
| Pediatrics | |
| Pediatric Gastroenterology |
Training Experience
| 1974 | Residency, Univ. of Tennessee-Health Services |
| 1977 | Fellowship, Johns Hopkins Hospital |
| 1978 | Fellowship, University of Wisconsin Hospital & Clinics |
Education/Academic qualification
Medicine, MD, University of Tennessee
… → 1971
Research interests keywords
- Autoimmune Diseases
- Digestive System (including gallbladder and liver)
- Immune System
- Pediatrics
- Transplantation
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Continuation of ChiLDREN, the Childhood Liver Disease Research Network
Whitington, P. F., Alonso, E. M., Bass, L. M. & Melin-Aldana, H.
National Institute of Diabetes and Digestive and Kidney Diseases
8/10/14 → 8/31/19
Project: Research project
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Continuation of ChiLDREN, the Childhood Liver Disease Research Network
Whitington, P. F., Alonso, E. M., Bass, L. M., Melin-Aldana, H. & Taylor, S. A.
National Institute of Diabetes and Digestive and Kidney Diseases
8/10/14 → 8/31/19
Project: Research project
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Continuation of ChiLDREN, the Childhood Liver Disease Research Network
Whitington, P. F., Alonso, E. M., Bass, L. M. & Melin-Aldana, H.
National Institute of Diabetes and Digestive and Kidney Diseases
8/10/14 → 8/31/19
Project: Research project
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Progression of Fatty Liver Disease in Children Receiving Standard of Care Lifestyle Advice
NASH Clinical Research Network, Nov 2020, In: Gastroenterology. 159, 5, p. 1731-1751.e10Research output: Contribution to journal › Article › peer-review
40 Scopus citations -
Oligoclonal immunoglobulin repertoire in biliary remnants of biliary atresia
Taylor, S. A., Malladi, P., Pan, X., Wechsler, J. B., Hulse, K. E., Perlman, H. R. & Whitington, P. F., Dec 1 2019, In: Scientific reports. 9, 1, 4508.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Antenatal Treatment with Intravenous Immunoglobulin to Prevent Gestational Alloimmune Liver Disease: Comparative Effectiveness of 14-Week versus 18-Week Initiation
Whitington, P. F., Kelly, S., Taylor, S. A., Nóbrega, S., Schreiber, R. A., Sokal, E. M. & Hibbard, J. U., Apr 1 2018, In: Fetal Diagnosis and Therapy. 43, 3, p. 218-225 8 p.Research output: Contribution to journal › Article › peer-review
24 Scopus citations -
Clinically Actionable Hypercholesterolemia and Hypertriglyceridemia in Children with Nonalcoholic Fatty Liver Disease
Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN), Jul 2018, In: journal of pediatrics. 198, p. 76-83.e2Research output: Contribution to journal › Article › peer-review
20 Scopus citations -
Hepatic Histology and Morphometric Measurements in Idiopathic Extrahepatic Portal Vein Thrombosis in Children, Correlated to Clinical Outcome of Meso-Rex Bypass
Tantemsapya, N., Superina, R., Wang, D., Kronauer, G., Whitington, P. F. & Melin-Aldana, H., Jun 1 2018, In: Annals of surgery. 267, 6, p. 1179-1184 6 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations