Grants per year
Personal profile
Research Interests
Clinical Interests: asthma, chronic obstructive pulmonary disease (COPD), interstitial lung disease, SARCOIDOSIS. Research Interests: airway inflammation and remodeling in asthma and COPD; effects of hypercapnia (elevated levels of CO2) on innate immunity and host defense in the lung.
Certifications and Licenses
| Internal Medicine | |
| Pulmonary Disease | |
| Critical Care Medicine |
Training Experience
| 1983 | Residency, Bronx Municipal Hospital Center |
| 1984 | Fellowship, Bronx Municipal Hospital Center |
| 1987 | Fellowship, University of Michigan Health System |
Education/Academic qualification
MD, Wayne State University School of Medicine
… → 1980
Keywords
- Asthma
- Chronic Obstructive Pulmonary Disease (COPD)
- Idiopathic Interstitial Lung Disease
- Lungs / Breathing Problems
- Respiratory Diseases
Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.
- 4 Similar Profiles
Hypercapnia
Medicine & Life Sciences
Alveolar Macrophages
Medicine & Life Sciences
Arachidonic Acid
Medicine & Life Sciences
Lung
Medicine & Life Sciences
Epithelial Cells
Medicine & Life Sciences
Arachidonate 5-Lipoxygenase
Medicine & Life Sciences
Alveolar Epithelial Cells
Medicine & Life Sciences
Leukotriene C4
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Grants 1992 2022
Foundation for Sarcoidosis Research Clinical Studies Network (FSR-CSN): Northwestern Medicine Program
Foundation for Sarcoidosis Research
7/1/18 → 6/30/20
Project: Research project
Sarcoidosis
Medicine
Research
Adrenal Cortex Hormones
Immunosuppressive Agents
Dissecting the role of lung macrophages in sarcoidosis using genomic approaches
Budinger, G. S., Sporn, P. H. & Winter, D. R.
3/1/18 → 2/29/20
Project: Research project
Sarcoidosis
Macrophages
Lung
Gene Regulatory Networks
Epigenomics
Hypercapnia and Suppression of Anti-viral Host Defense
National Heart, Lung, and Blood Institute
9/1/17 → 8/31/20
Project: Research project
Hypercapnia
Influenza A virus
Autophagy
Antiviral Agents
Macrophages
2018 Meeting of the American Association of Sarcoidosis and Other Granulomatous Disorders (AASOG)
National Heart, Lung, and Blood Institute
3/1/18 → 2/28/19
Project: Research project
Sarcoidosis
Research Personnel
Lung
African Americans
Therapeutics
Research Output 1977 2019
Mechanism of benefit of non-invasive ventilation in COPD with hypercapnic respiratory failure
Sporn, P. H., Casalino Matsuda, M. S. & Gates, K. L., May 1 2019, In : Respirology. 24, 5, 1 p.Research output: Contribution to journal › Letter
Noninvasive Ventilation
Respiratory Insufficiency
Chronic Obstructive Pulmonary Disease
1
Citation
(Scopus)
A role for heat shock factor 1 in hypercapnia-induced inhibition of inflammatory cytokine expression
Lu, Z., Casalino Matsuda, M. S., Nair, A., Buchbinder, A., Budinger, GR. S., Sporn, P. H. & Gates, K. L., Jul 1 2018, In : FASEB Journal. 32, 7, p. 3614-3622 9 p.Research output: Contribution to journal › Article
Hypercapnia
Shock
Hot Temperature
Cytokines
Interleukin-6
Dynamics of influenza-induced lung-resident memory T cells, anatomically and functionally distinct lung mesenchymal populations, and dampening of acute lung injury by neutrophil transfer of micro-RNA-223 to lung epithelial cells
Ferguson, K. T., McQuattie-Pimentel, A. C., Malsin, E. S. & Sporn, P. H., Sep 1 2018, In : American Journal of Respiratory Cell and Molecular Biology. 59, 3, p. 397-399 3 p.Research output: Contribution to journal › Article
Acute Lung Injury
Transfer RNA
MicroRNAs
Human Influenza
Neutrophils
Health equity in Israel
Health Advisory Council of Jewish Voice for Peace, Feb 10 2018, In : The Lancet. 391, 10120, p. 534-535 2 p.Research output: Contribution to journal › Letter
Israel
Health Equity
1
Citation
(Scopus)
Hypercapnia Alters Expression of Immune Response, Nucleosome Assembly and Lipid Metabolism Genes in Differentiated Human Bronchial Epithelial Cells
Casalino Matsuda, M. S., Wang, N., Ruhoff, P. T., Matsuda, H., Nlend, M. C., Nair, A., Szleifer, I. G., Beitel, G. J., Sznajder, J. I. & Sporn, P. H., Dec 1 2018, In : Scientific Reports. 8, 1, 13508.Research output: Contribution to journal › Article
Hypercapnia
Nucleosomes
Lipid Metabolism
Epithelial Cells
Carbon Monoxide