• 1558 Citations
1977 …2024

Research output per year

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Research Output

2019

Academic medicine and political agendas

Jewish Voice for Peace Health Advisory Council, Oct 19 2019, In : The Lancet. 394, 10207, p. 1410-1411 2 p.

Research output: Contribution to journalLetter

Elevated CO2 regulates the Wnt signaling pathway in mammals, Drosophila melanogaster and Caenorhabditis elegans

Shigemura, M., Lecuona, E., Angulo, M., Dada, L. A., Edwards, M. B., Welch, L. C., Casalino-Matsuda, S. M., Sporn, P. H. S., Vadász, I., Helenius, I. T., Nader, G. A., Gruenbaum, Y., Sharabi, K., Cummins, E., Taylor, C., Bharat, A., Gottardi, C. J., Beitel, G. J., Kaminski, N., Budinger, G. R. S. & 2 others, Berdnikovs, S. & Sznajder, J. I., Dec 1 2019, In : Scientific reports. 9, 1, 18251.

Research output: Contribution to journalArticle

Open Access
2018

A role for heat shock factor 1 in hypercapnia-induced inhibition of inflammatory cytokine expression

Lu, Z., Casalino-Matsuda, S. M., Nair, A., Buchbinder, A., Scott Budinger, G. R., Sporn, P. H. S. & Gates, K. L., Jul 2018, In : FASEB Journal. 32, 7, p. 3614-3622 9 p.

Research output: Contribution to journalArticle

5 Scopus citations

Health equity in Israel

Health Advisory Council of Jewish Voice for Peace, Feb 10 2018, In : The Lancet. 391, 10120, p. 534-535 2 p.

Research output: Contribution to journalLetter

1 Scopus citations
6 Scopus citations
2016

Dimensions and Role-Specific Mediators of Surrogate Trust in the ICU

Hutchison, P. J., McLaughlin, K., Corbridge, T., Michelson, K. N., Emanuel, L., Sporn, P. H. S. & Crowley-Matoka, M., Dec 1 2016, In : Critical care medicine. 44, 12, p. 2208-2214 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

Focused Screening Identifies Evoxine as a Small Molecule That Counteracts CO2-Induced Immune Suppression

Helenius, I. T., Nair, A., Bittar, H. E. T., Sznajder, J. I., Sporn, P. H. S. & Beitel, G. J., Apr 1 2016, In : Journal of Biomolecular Screening. 21, 4, p. 363-371 9 p.

Research output: Contribution to journalArticle

3 Scopus citations

Hypercapnia suppresses the HIF-dependent adaptive response to hypoxia

Selfridge, A. C., Cavadas, M. A. S., Scholz, C. C., Campbell, E. L., Welch, L. C., Lecuona, E., Colgan, S. P., Barrett, K. E., Sporn, P. H. S., Sznajder, J. I., Cummins, E. P. & Taylor, C. T., May 27 2016, In : Journal of Biological Chemistry. 291, 22, p. 11800-11808 9 p.

Research output: Contribution to journalArticle

20 Scopus citations

Identification of drosophila Zfh2 as a mediator of hypercapnic immune regulation by a genome-wide RNA interference screen

Helenius, I. T., Haake, R. J., Kwon, Y. J., Hu, J. A., Krupinski, T., Marina Casalino-Matsuda, S., Sporn, P. H. S., Sznajder, J. I. & Beitel, G. J., Jan 15 2016, In : Journal of Immunology. 196, 2, p. 655-667 13 p.

Research output: Contribution to journalArticle

9 Scopus citations

Pleural hypercarbia after lung surgery is associated with persistent alveolopleural fistulae

Bharat, A., Graf, N., Mullen, A., Kanter, J., Andrei, A. C., Sporn, P. H. S., DeCamp, M. M. & Sznajder, J. I., Jan 2016, In : CHEST. 149, 1, p. 220-227 8 p.

Research output: Contribution to journalArticle

7 Scopus citations

Wandering pleural mesothelial fatty cyst

Nicholson, T. T., Raparia, K., Mutlu, G. M., Sporn, P. H. S. & Bharat, A., Nov 1 2016, In : American journal of respiratory and critical care medicine. 194, 9, p. 1164-1165 2 p.

Research output: Contribution to journalComment/debate

2015

Decreased CXCL12 is associated with impaired alveolar epithelial cell migration and poor lung healing after lung resection

Kanter, J. A., Sun, H., Chiu, S., DeCamp, M. M., Sporn, P. H. S., Sznajder, J. I. & Bharat, A., Oct 1 2015, In : Surgery (United States). 158, 4, p. 1073-1082 10 p.

Research output: Contribution to journalArticle

4 Scopus citations
27 Scopus citations

Pleural gas analysis for detection of alveolopleural fistulae

Bharat, A., Graf, N., Cassidy, E., Smith, S., Gillespie, C., Meyerson, S., Sporn, P. H. S., Sznajder, J. I. & Decamp, M. M., Jun 1 2015, In : Annals of Thoracic Surgery. 99, 6, p. 2179-2182 4 p.

Research output: Contribution to journalArticle

2 Scopus citations
2014
3 Scopus citations

Carbon dioxide-sensing in organisms and its implications for human disease

Cummins, E. P., Selfridge, A. C., Sporn, P. H., Sznajder, J. I. & Taylor, C. T., Mar 1 2014, In : Cellular and Molecular Life Sciences. 71, 5, p. 831-845 15 p.

Research output: Contribution to journalReview article

61 Scopus citations
2013

Fever control using external cooling in septic shock

Jaitovich, A. & Sporn, P. H. S., Jun 1 2013, In : American journal of respiratory and critical care medicine. 187, 11, 1 p.

Research output: Contribution to journalLetter

Hypercapnia impairs lung neutrophil function and increases mortality in murine Pseudomonas pneumonia

Gates, K. L., Howell, H. A., Nair, A., Vohwinkel, C. U., Welch, L. C., Beitel, G. J., Hauser, A. R., Sznajder, J. I. & Sporn, P. H. S., Nov 1 2013, In : American journal of respiratory cell and molecular biology. 49, 5, p. 821-828 8 p.

Research output: Contribution to journalArticle

46 Scopus citations

Suppression of inflammation and acute lung injury by Miz1 via repression of C/EBP-δ

Do-Umehara, H. C., Chen, C., Urich, D., Zhou, L., Qiu, J., Jang, S., Zander, A., Baker, M. A., Eilers, M., Sporn, P. H. S., Ridge, K. M., Sznajder, J. I., Budinger, G. R. S., Mutlu, G. M., Lin, A. & Liu, J., May 1 2013, In : Nature Immunology. 14, 5, p. 461-469 9 p.

Research output: Contribution to journalArticle

46 Scopus citations
2012

Hypercapnia: A nonpermissive environment for the lung

Vadász, I., Hubmayr, R. D., Nin, N., Sporn, P. H. S. & Sznajder, J. I., Apr 1 2012, In : American journal of respiratory cell and molecular biology. 46, 4, p. 417-421 5 p.

Research output: Contribution to journalReview article

38 Scopus citations
2010
68 Scopus citations

Myosin light chain kinase mediates transcellular intravasation of breast cancer cells through the underlying endothelial cells: A three-dimensional FRET study

Khuon, S., Liang, L., Dettman, R. W., Sporn, P. H. S., Wysolmerski, R. B. & Chew, T. L., Feb 1 2010, In : Journal of cell science. 123, 3, p. 431-440 10 p.

Research output: Contribution to journalArticle

75 Scopus citations
2009

Elevated CO2 suppresses specific Drosophila innate immune responses and resistance to bacterial infection

Helenius, I. T., Krupinski, T., Turnbull, D. W., Gruenbaum, Y., Silverman, N., Johnson, E. A., Sporn, P. H. S., Sznajder, J. I. & Beitel, G. J., Nov 3 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 44, p. 18710-18715 6 p.

Research output: Contribution to journalArticle

51 Scopus citations

Essential roles for early growth response transcription factor Egr-1 in tissue fibrosis and wound healing

Wu, M., Melichian, D. S., De La Garza, M., Gruner, K., Bhattacharyya, S., Barr, L., Nair, A., Shahrara, S., Sporn, P. H. S., Mustoe, T. A., Tourtellotte, W. G. & Varga, J., Jan 1 2009, In : American Journal of Pathology. 175, 3, p. 1041-1055 15 p.

Research output: Contribution to journalArticle

70 Scopus citations
2008

A mechanism of benefit of soy genistein in asthma: Inhibition of eosinophil p38-dependent leukotriene synthesis

Kalhan, R., Smith, L. J., Nlend, M. C., Nair, A., Hixon, J. L. & Sporn, P. H., Jan 1 2008, In : Clinical and Experimental Allergy. 38, 1, p. 103-112 10 p.

Research output: Contribution to journalArticle

42 Scopus citations
2007

Orbital emphysema in COPD with bronchopleural fistula

Upadhyay, D. & Sporn, P. H., Aug 9 2007, In : International Journal of COPD. 2, 2, p. 187-188 2 p.

Research output: Contribution to journalArticle

3 Scopus citations
2006
67 Scopus citations
2005

Tuberculin skin test in diagnosis of latent tuberculosis infection

Kuźniar, T. J., Kasibowska-Kuźniar, K. & Sporn, P. H. S., Aug 31 2005, In : Advances in Clinical and Experimental Medicine. 14, 4, p. 799-806 8 p.

Research output: Contribution to journalReview article

2004

Leukotriene D4 Activates Alveolar Epithelial Na,K-ATPase and Increases Alveolar Fluid Clearance

Sloniewsky, D. E., Ridge, K. M., Adir, Y., Fries, F. P., Briva, A., Sznajder, J. I. & Sporn, P. H. S., Feb 1 2004, In : American Journal of Respiratory and Critical Care Medicine. 169, 3, p. 407-412 6 p.

Research output: Contribution to journalArticle

33 Scopus citations
2003

An in vitro airway wall model of remodeling

Choe, M. M., Sporn, P. H. & Swartz, M. A., Aug 1 2003, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 285, 2 29-2

Research output: Contribution to journalArticle

65 Scopus citations
2002

Cellular biomechanics in the lung

Waters, C. M., Sporn, P. H. S., Liu, M. & Fredberg, J. J., Sep 1 2002, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 283, 3 27-3, p. L503-L509

Research output: Contribution to journalArticle

55 Scopus citations
2001

Cellular mechanics in human blood eosinophils and leukotriene C 4 synthesis

Waters, C. M., Savla, U., Kuagoolwongse, P. & Sporn, P. H., Dec 1 2001, In : American Society of Mechanical Engineers, Bioengineering Division (Publication) BED. 50, p. 635-636 2 p.

Research output: Contribution to journalConference article

Prostaglandin E2 regulates wound closure in airway epithelium

Savla, U., Appel, H. J., Sporn, P. H. S. & Waters, C. M., Mar 1 2001, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 280, 3 24-3, p. L421-L431

Research output: Contribution to journalArticle

77 Scopus citations
1999

Decreased leukotriene C4 synthesis accompanies adherence-dependent nuclear import of 5-lipoxygenasee in human blood eosinophils

Brock, T. G., Anderson, J. A., Fries, F. P., Peters-Golden, M. & Sporn, P. H. S., Feb 1 1999, In : Journal of Immunology. 162, 3, p. 1669-1676 8 p.

Research output: Contribution to journalArticle

60 Scopus citations

Keratinocyte growth factor stimulates bronchial epithelial cell proliferation in vitro and in vivo

Michelson, P. H., Tigue, M., Panos, R. J. & Sporn, P. H. S., Oct 1 1999, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 277, 4 21-4

Research output: Contribution to journalArticle

38 Scopus citations
1998

Keratinocyte growth factor promotes alveolar epithelial cell DNA repair after H2O2 exposure

Kristina, I. W., Pollack, N., Panos, R. J., Sporn, P. H. S. & Kamp, D. W., Nov 9 1998, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 275, 4 19-4

Research output: Contribution to journalArticle

76 Scopus citations

Regulation of 5-lipoxygenase activity in mononuclear phagocytes: Characterization of an endogenous cytosolic inhibitor

Coffey, M. J., Wilcoxen, S. E., Sporn, P. H. & Peters-Golden, M., Jun 1 1998, In : Prostaglandins and Other Lipid Mediators. 56, 2-3, p. 103-117 15 p.

Research output: Contribution to journalArticle

13 Scopus citations
1997

Cyclic stretch of airway epithelium inhibits prostanoid synthesis

Savla, U., Sporn, P. H. S. & Waters, C. M., Dec 9 1997, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 273, 5 17-5

Research output: Contribution to journalArticle

39 Scopus citations

Cyclic stretch of airway epithelium inhibits prostanoid synthesis

Savla, U., Sporn, P. H. S. & Waters, C. M., Dec 1 1997, In : American Journal of Physiology. 273, 5 PART 1, p. L1007-L1012

Research output: Contribution to journalArticle

4 Scopus citations
1 Scopus citations

Reduced superoxide dismutase in lung cells of patients with asthma

Smith, L. J., Shamsuddin, M., Sporn, P. H. S., Denenberg, M. & Anderson, J., May 3 1997, In : Free Radical Biology and Medicine. 22, 7, p. 1301-1307 7 p.

Research output: Contribution to journalArticle

130 Scopus citations
1996

Increased 5-lipoxygenase metabolism in the lungs of human subjects exposed to ozone

Coffey, M. J., Wheeler, C. S., Gross, K. B., Eschenbacher, W. L., Sporn, P. H. S. & Peters-Golden, M., Dec 18 1996, In : Toxicology. 114, 3, p. 187-197 11 p.

Research output: Contribution to journalArticle

28 Scopus citations
1992
28 Scopus citations

Membrane association of active 5-lipoxygenase in resting cells: Evidence for novel regulation of the enzyme in the rat alveolar macrophage

Coffey, M., Peters-Golden, M., Fantone, J. C. & Sporn, P. H. S., Jan 1 1992, In : Journal of Biological Chemistry. 267, 1, p. 570-576 7 p.

Research output: Contribution to journalArticle

70 Scopus citations
1991

Basal activation of protein kinase C in rat alveolar macrophages: Implications for arachidonate metabolism

Peters-Golden, M., McNish, R. W., Sporn, P. H. S. & Balazovich, K., Dec 1 1991, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 261, 6 5-3

Research output: Contribution to journalArticle

28 Scopus citations
1990

Complex effects of in vitro hyperoxia on alveolar macrophage arachidonic acid metabolism.

Sporn, P. H., Murphy, T. M. & Peters-Golden, M., Jan 1 1990, In : American Journal of Respiratory Cell and Molecular Biology. 2, 1, p. 81-90 10 p.

Research output: Contribution to journalArticle

11 Scopus citations