Grants per year
Grants
- 30 Finished
Search results
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Finished
The role of Bile Acids in Gastroesophageal Reflux Disease (GERD)
Kahrilas, P. J. (PD/PI)
Ironwood Pharmaceuticals, Inc.
12/10/19 → 6/11/23
Project: Research project
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Disordered Tissue Biomechanics as a Driver of Esophageal Disease
Pandolfino, J. E. (PD/PI), Tetreault, M.-P. (PD/PI), Budinger, G. S. (Co-Investigator), Carlson, D. A. (Co-Investigator), Ciolino, J. D. (Co-Investigator), Hinchcliff, M. E. (Co-Investigator), Hirano, I. (Co-Investigator), Passman, R. S. (Co-Investigator), Schauer, J. M. (Co-Investigator), Taft, T. N. (Co-Investigator), Yang, G.-Y. (Co-Investigator), Espinosa, H. D. (Other), Gonsalves, N. P. (Other), Kahrilas, P. J. (Other) & Patankar, N. A. (Other)
National Institute of Diabetes and Digestive and Kidney Diseases
7/15/18 → 6/30/24
Project: Research project
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Prot# C1701-201: A Multicenter, Randomized, Double-Blind Placebo-controlled, Parallel-group, Single-dose, Phase 2a Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of IW-1701 in Patients with Achalasia.
Kahrilas, P. J. (PD/PI)
INC Research, LLC, Ironwood Pharmaceuticals, Inc.
5/9/17 → 5/9/20
Project: Research project
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The mechanics of symptom generation in dysphagia
Pandolfino, J. E. (PD/PI), Hirano, I. (Co-PD/PI), Kahrilas, P. J. (Co-PD/PI), Patankar, N. A. (Co-PD/PI) & Kwasny, M. J. (Other)
National Institute of Diabetes and Digestive and Kidney Diseases
8/15/14 → 6/30/19
Project: Research project
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Defining Clinically Relevant Phenotypes of PPI Non-Responders
Pandolfino, J. E. (PD/PI), Kahrilas, P. J. (Co-Investigator) & Martinovich, Z. (Co-Investigator)
National Institute of Diabetes and Digestive and Kidney Diseases
4/1/12 → 3/31/16
Project: Research project
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The Esophagogastric Junction in Health and Disease
Kahrilas, P. J. (PD/PI) & Pandolfino, J. E. (Co-PD/PI)
National Institute of Diabetes and Digestive and Kidney Diseases
6/25/11 → 8/31/17
Project: Research project
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The Mechanics of Symptom Generation in Dysphagia
Pandolfino, J. E. (PD/PI), Hirano, I. (Co-PD/PI), Kahrilas, P. J. (Co-PD/PI), Rademaker, A. W. (Co-PD/PI), Hirano, I. (Co-Investigator), Kahrilas, P. J. (Co-Investigator) & Rademaker, A. W. (Co-Investigator)
National Institute of Diabetes and Digestive and Kidney Diseases
7/1/09 → 6/30/14
Project: Research project
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Prot# D9120C00027: Validation of Patient-Reported Outcome Measures for the Assessment of GERD Symptoms and Their Subsequent Impact on Patients with a Partial Response to PPI Treatment in a Two Part Multi-Center Phase IIA Study Including a Four Week Random
Pandolfino, J. E. (PD/PI), Hirano, I. (Co-PD/PI) & Kahrilas, P. J. (Co-PD/PI)
AstraZeneca Pharmaceuticals LP
10/20/08 → 10/20/11
Project: Research project
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Measurement of the Compliance of Esophagogastric Junction During Esophagogastroduodenoscopy to Predict Abnormal Esophageal Acid Exposure
Pandolfino, J. E. (PD/PI), Hirano, I. (Co-PD/PI), Hungness, E. (Co-PD/PI), Kahrilas, P. J. (Co-PD/PI) & Soper, N. J. (Co-PD/PI)
5/16/08 → 5/16/11
Project: Research project
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The Esophagogastric Junction in Health and Disease
Kahrilas, P. J. (PD/PI), Pandolfino, J. E. (Co-PD/PI) & Pandolfino, J. E. (Co-Investigator)
National Institute of Diabetes and Digestive and Kidney Diseases
4/15/07 → 9/22/11
Project: Research project
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The Esophagogastric Junction in Health and Disease
Kahrilas, P. J. (PD/PI) & Pandolfino, J. E. (Co-PD/PI)
National Institute of Diabetes and Digestive and Kidney Diseases
9/19/06 → 3/31/07
Project: Research project
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The Esophagogastric Junction in Health and Disease
Kahrilas, P. J. (PD/PI) & Pandolfino, J. E. (Co-PD/PI)
National Institute of Diabetes and Digestive and Kidney Diseases
9/19/06 → 3/31/07
Project: Research project
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Prot# IRUSESOM0378: Proximal Extent of the "Acid Pocket" in Asymptomatic Controls and Symptomatic Patients with GERD and Non-ulcer Dyspepsia
Pandolfino, J. E. (PD/PI), Kahrilas, P. J. (Co-PD/PI) & Lee, T. J. (Co-PD/PI)
8/28/06 → 6/15/09
Project: Research project
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Prot# IRUSESOM0378: Proximal Extent of the "Acid Pocket" in Asymptomatic Controls and Symptomatic Patients with GERD and Non-ulcer Dyspepsia
Pandolfino, J. E. (PD/PI), Kahrilas, P. J. (Co-PD/PI) & Lee, T. J. (Co-PD/PI)
8/28/06 → 6/15/09
Project: Research project
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Oropharyngeal Function After Radiotherapy with IMRT
Agulnik, M. (Co-PD/PI), Kahrilas, P. J. (Co-PD/PI), Mittal, B. B. (Co-PD/PI), Patel, J. D. (Co-PD/PI), Pelzer, H. J. (Co-PD/PI) & Rademaker, A. W. (Other)
National Institute on Deafness and Other Communication Disorders
7/10/06 → 6/30/12
Project: Research project
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Clinical Evaluation of The Bravo Wireless pH Monitoring System
Pandolfino, J. E. (PD/PI), Hirano, I. (Co-PD/PI) & Kahrilas, P. J. (Co-PD/PI)
8/15/05 → 8/14/06
Project: Research project
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Evaluation of Duodenal Acid Exposure in Healthy Controls and Patients with Nonulcer Dyspepsia Using a Radiotelemetry pH Monitoring System
Kahrilas, P. J. (Co-PD/PI)
AstraZeneca Pharmaceuticals LP
2/24/05 → 4/30/08
Project: Research project
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Prot# D9770C00012: A Randomised, Double-Blind, Multicentre Dose-Finding Phase IIb Study for up to 8wks' Treatment w/AZD0865 25,50,75mg & Esomeprazole 40mg, Given Orally 1x Daily for the Healing of Erosive Esophagitis in Adult Subjects w/GERD w/Erosive Eso
Pandolfino, J. E. (PD/PI), Hirano, I. (Co-PD/PI), Kahrilas, P. J. (Co-PD/PI) & Lee, T. J. (Co-PD/PI)
ICON Clinical Research, LLC, AstraZeneca LP
10/13/04 → 3/20/07
Project: Research project
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Prot# D9770C00012: A Randomised, Double-Blind, Multicentre Dose-Finding Phase IIb Study for up to 8wks' Treatment w/AZD0865 25,50,75mg & Esomeprazole 40mg, Given Orally 1x Daily for the Healing of Erosive Esophagitis in Adult Subjects w/GERD w/Erosive Eso
Pandolfino, J. E. (PD/PI), Hirano, I. (Co-PD/PI), Kahrilas, P. J. (Co-PD/PI) & Lee, T. J. (Co-PD/PI)
ICON Clinical Research, LLC, AstraZeneca LP
10/13/04 → 3/20/07
Project: Research project
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Prot# D9770C00011: A 4-wk, Randomised, Double-Blind, Multicenter, Dose-Finding Phase IIb Study w/AZD0865 25,50,75mg & Esomeprazole 20mg, Given Orally 1x Daily for the Treatment of GERD w/out Erosive Esophagitis According to the LA Classification in Adult
Pandolfino, J. E. (PD/PI), Hirano, I. (Co-PD/PI), Kahrilas, P. J. (Co-PD/PI) & Lee, T. J. (Co-PD/PI)
ICON Clinical Research, LLC, AstraZeneca LP
10/13/04 → 4/11/07
Project: Research project
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Simultaneous Measurement of Esophageal pH Using the Bravo System and a Conventional Catheter Based pH System: A Validation Study
Pandolfino, J. E. (PD/PI), Hirano, I. (Co-PD/PI) & Kahrilas, P. J. (Co-PD/PI)
7/1/04 → 12/31/05
Project: Research project
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Simultaneous Measurement of Acid Exposure in the Cardia of the Stomach and Esophagus Using a Radiotelemetry pH Monitoring System
Pandolfino, J. E. (PD/PI) & Kahrilas, P. J. (Co-PD/PI)
5/24/04 → 4/11/07
Project: Research project
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Simultaneous Measurement of Acid Exposure in the Cardia of the Stomach and Esophagus Using a Radiotelemetry pH Monitoring System
Pandolfino, J. E. (PD/PI) & Kahrilas, P. J. (Co-PD/PI)
5/24/04 → 4/11/07
Project: Research project
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Prot# BSC-GERD-2003-01-Rev 1: A Randomized, Prospective, Controlled Study of Enteryx® for the Treatment of Gastroesophageal Reflux Disease (GERD)
Kahrilas, P. J. (PD/PI), Hirano, I. (Co-PD/PI) & Pandolfino, J. E. (Co-PD/PI)
3/22/04 → 3/21/10
Project: Research project
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Prot# G010136-01: An Evaluation of the Medtronic Gatekeeper? System in the Treatment of Subjects with Gastroesophageal Reflux Disease (GERD) [Gatekeeper? Reflux Repair System for Reducing Clinical Symptoms Associated with GERD]
Kahrilas, P. J. (PD/PI), Hirano, I. (Co-PD/PI), Lee, T. J. (Co-PD/PI) & Pandolfino, J. E. (Co-PD/PI)
3/10/04 → 3/23/07
Project: Research project