Grants per year
Personal profile
Research Interests
My interests include treating primary brain tumors such as gliomas and meningiomas. I also have a specific interest in metastatic disease to the brain from systemic cancers such as melanoma, lung and breast cancer and lead multiple trials in both primary brain tumors and metastatic disease. I am interested in providing novel care to my patients while maintaining quality of life.
Certifications and Licenses
Neurology |
Training Experience
2008 | Internship, Evanston Hospital |
2011 | Residency, Northwestern University, McGaw Medical Center |
2012 | Fellowship, Northwestern University, McGaw Medical Center |
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
MD, Medicine, Northeastern Ohio University
… → 2007
Research interests keywords
- Brain Cancer / Nervous System Cancer
- Neuro-Oncology
- Neurology
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- 1 Similar Profiles
Collaborations and top research areas from the last five years
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Project 4
Ahmed, A. U., Ganger, D. R., Kumthekar, P. U., Miska, J. M. & Stupp, R.
8/1/23 → 7/31/28
Project: Research project
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Prot #CL1-95032-005: A Phase 1, Safety Lead-in and Randomized, Open-label, Perioperative Study of Vorasidenib in Combination with Pembrolizumab in Subjects with Recurrent or Progressive Enhancing IDH-1 Mutant Astrocytomas
PPD Development, Servier Bio-Innovation LLC
5/22/23 → 5/22/26
Project: Research project
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A Phase II Clinical Trial in Newly Diagnosed Glioblastoma Patients Treated with WP1066 and Radiation
Heimberger, A. B., Kumthekar, P. U., Hill, V. B., Kocherginsky, M. & Sachdev, S.
5/5/23 → 4/30/28
Project: Research project
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(OE) BIOC-046: A Longitudinal Therapy Response Monitoring Study in Subjects with Leptomeningeal Metastases using CNSide (CSF Tumor Cells) Compared to Standard of Care (CSF Cytology, Clinical Evaluation, and Imaging).
ICON Clinical Research, LLC, Biocept, Inc.
4/11/23 → 4/11/26
Project: Research project
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Alliance A071401: Phase II Trial of Focal Adhesion Kinase Inhibition in Meningiomas with Somatic NF2 Mutations
Brastianos, P. K., Twohy, E. L., Gerstner, E. R., Kaufmann, T. J., Iafrate, A. J., Lennerz, J., Jeyapalan, S., Piccioni, D. E., Monga, V., Fadul, C. E., Schiff, D., Taylor, J. W., Chowdhary, S. A., Bettegowda, C., Ansstas, G., De La Fuente, M., Anderson, M. D., Shonka, N., Damek, D., Carrillo, J., & 25 others , Jan 20 2023, In: Journal of Clinical Oncology. 41, 3, p. 618-628 11 p.Research output: Contribution to journal › Article › peer-review
15 Scopus citations -
A phase I/II study of intrathecal trastuzumab in human epidermal growth factor receptor 2-positive (HER2-positive) cancer with leptomeningeal metastases: Safety, efficacy, and cerebrospinal fluid pharmacokinetics
Kumthekar, P. U., Avram, M. J., Lassman, A. B., Lin, N. U., Lee, E., Grimm, S. A., Schwartz, M., Bell Burdett, K. L., Lukas, R. V., Dixit, K., Perron, I., Zhang, H., Gradishar, W. J., Pentsova, E. I., Jeyapalan, S., Groves, M. D., Melisko, M. & Raizer, J. J., Mar 14 2023, In: Neuro-oncology. 25, 3, p. 557-565 9 p.Research output: Contribution to journal › Article › peer-review
17 Scopus citations -
A Phase II Single-arm Study of Palbociclib in Patients With HER2-positive Breast Cancer With Brain Metastases and Analysis of ctDNA in Patients With Active Brain Metastases
Shah, A. N., Santa-Maria, C. A., Mukhija, D., Shah, N., Kang, A. K., Kumthekar, P., Burdett, K., Chandra, S., Chang, J., Tsarwhas, D., Woodman, J., Jovanovic, B., Gerratana, L., Gradishar, W. & Cristofanilli, M., Apr 2023, In: Clinical breast cancer. 23, 3, p. 324-329 6 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
BRAF-MEK Inhibition in Newly Diagnosed Papillary Craniopharyngiomas
Brastianos, P. K., Twohy, E., Geyer, S., Gerstner, E. R., Kaufmann, T. J., Tabrizi, S., Kabat, B., Thierauf, J., Ruff, M. W., Bota, D. A., Reardon, D. A., Cohen, A. L., De La Fuente, M. I., Lesser, G. J., Campian, J., Agarwalla, P. K., Kumthekar, P., Mann, B., Vora, S., Knopp, M., & 8 others , 2023, In: New England Journal of Medicine. 389, 2, p. 118-126 9 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Cerebrospinal fluid-administered therapies for leptomeningeal metastases from solid tumors
Baskaran, A. B., Bhatia, A., Kumthekar, P., Boire, A. & Lukas, R. V., Aug 1 2023, In: Future Oncology. 19, 26, p. 1801-1807 7 p.Research output: Contribution to journal › Review article › peer-review
Datasets
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CSF-Administered Therapies for Leptomeningeal Metastases from Solid Tumors - supplementary material
Baskaran, A. B. (Contributor), Bhatia, A. (Creator), Kumthekar, P. U. (Creator), Boire, A. (Creator) & Lukas, R. V. (Contributor), Future Science Group, 2023
DOI: 10.25402/fon.24182565, https://future-science-group.figshare.com/articles/dataset/CSF-Administered_Therapies_for_Leptomeningeal_Metastases_from_Solid_Tumors_-_supplementary_material/24182565
Dataset
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Sex-specific impact of patterns of imageable tumor growth on survival of primary glioblastoma patients
Whitmire, P. (Creator), Rickertsen, C. R. (Creator), Hawkins-Daarud, A. (Creator), Carrasco, E. (Creator), Lorence, J. (Creator), De Leon, G. (Contributor), Curtin, L. (Creator), Bayless, S. (Creator), Clark-Swanson, K. (Creator), Peeri, N. C. (Creator), Corpuz, C. (Creator), Lewis-De Los Angeles, C. P. (Contributor), Bendok, B. R. (Creator), Gonzalez-Cuyar, L. (Creator), Vora, S. (Contributor), Mrugala, M. M. (Creator), Hu, L. S. (Creator), Wang, L. (Creator), Porter, A. (Contributor), Kumthekar, P. U. (Creator), Johnston, S. K. (Creator), Egan, K. M. (Creator), Gatenby, R. (Creator), Canoll, P. (Creator), Rubin, J. B. (Creator), Swanson, K. R. (Creator), Leon, G. D. (Creator), Mrugala, M. M. (Creator) & Gatenby, R. (Creator), figshare, 2020
DOI: 10.6084/m9.figshare.c.4985450, https://springernature.figshare.com/collections/Sex-specific_impact_of_patterns_of_imageable_tumor_growth_on_survival_of_primary_glioblastoma_patients/4985450
Dataset