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Priya U Kumthekar

  • 267 Citations
20102023
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Personal profile

Research Interests

My interests include treating primary brain tumors such as gliomas and meningiomas. I also have a specific interest in metastatic disease to the brain from systemic cancers such as melanoma, lung and breast cancer and lead multiple trials in both primary brain tumors and metastatic disease. I am interested in providing novel care to my patients while maintaining quality of life.

Certifications and Licenses

Neurology

Training Experience

2008Internship, Evanston Hospital
2011Residency, Northwestern University, McGaw Medical Center
2012Fellowship, Northwestern University, McGaw Medical Center

Education/Academic qualification

MD, Northeastern Ohio University

… → 2007

Keywords

  • Brain Cancer / Nervous System Cancer
  • Neuro-Oncology
  • Neurology

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Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Grants 2010 2023

DRUG ANG1005-CLN-07 - A Randomized Open-Label, Multi-Center Pivotal Study of ANG1005 Compared with Physician’s Best Choice in HER2-Negative Breast Cancer Patients with Newly Diagnosed Leptomeningeal Carcinomatosis and Previously Treated Brain Metastases

Kumthekar, P. U.

Angiochem Inc.

4/1/19 → 4/1/22

Project: Research project

Prot#17-546: NU DF18C03 - A Phase II Study of Atezolizumab in Combination with Pertuzumab Plus High-Dose Trastuzumab for the Treatment of Central Nervous System Metastases in Patients with Her2-Positive Breast Cancer

Kumthekar, P. U.

Dana Farber Cancer Institute, Genentech, Inc.

3/26/19 → 3/26/22

Project: Research project

Project 3: Using RNAi-based Spherical Nucleic Acid (SNA) Nanoconjugates Targeting Bcl2L12 to Promote Therapy-Induced Apoptosis in Glioblastoma Subproject for Institution # SP0045923

Kumthekar, P. U. & Stegh, A. H.

National Cancer Institute

8/17/18 → 7/31/23

Project: Research project

Nanoconjugates
Glioblastoma
RNA Interference
Nucleic Acids
Brain Neoplasms

SPORE for Translational Approaches to Brain Cancer

Ahmed, A. U., Balyasnikova, I. V., Bartom, E. T., Brat, D. J., Chandler, J. P., Cheng, S., Horbinski, C. M., Hu, B., James, C. D., Kumthekar, P. U., Leikin, R. G., Lesniak, M. S., Liu, B. P., Lukas, R. V., Mirkin, C. A., Platanias, L. C., Sachdev, S., Scholtens, D. M., Stegh, A. H., Stupp, R. & Wainwright, D. A.

National Cancer Institute

8/17/18 → 7/31/23

Project: Research project

Brain Neoplasms
Glioblastoma
Therapeutics
Neoplasms
Survival

Prot# 2401BT-002P: A Phase II, Multi-center, Open-label Study of a Conditionally Replicative Adenovirus (DNX-2401) with Pembrolizumab (KEYTRUDA®) for Recurrent Glioblastoma or Gliosarcoma

Kumthekar, P. U.

DNAtrix, Inc.

1/12/18 → 1/12/21

Project: Research project

Research Output 2013 2019

  • 267 Citations
  • 18 Article
  • 7 Review article
  • 2 Chapter
  • 1 Comment/debate

Long-term glioblastoma survival following recovery from cytomegalovirus colitis: A case report

Lamano, J. B., Quaggin-Smith, J. A., Horbinski, C. M., Tate, M. C., Grimm, S. A., Kumthekar, P. U. & Bloch, O., Jan 1 2019, In : Journal of Clinical Neuroscience.

Research output: Contribution to journal › Article

Colitis
Glioblastoma
Cytomegalovirus
temozolomide
Survival
2 Citations (Scopus)

Safety and efficacy of depatuxizumab mafodotin + temozolomide in patients with EGFR -amplified, recurrent glioblastoma: Results from an international phase I multicenter trial

Lassman, A. B., Van Den Bent, M. J., Gan, H. K., Reardon, D. A., Kumthekar, P. U., Butowski, N., Lwin, Z., Mikkelsen, T., Nabors, L. B., Papadopoulos, K. P., Penas-Prado, M., Simes, J., Wheeler, H., Walbert, T., Scott, A. M., Gomez, E., Lee, H. J., Roberts-Rapp, L., Xiong, H., Ansell, P. J. & 4 othersBain, E., Holen, K. D., Maag, D. & Merrell, R., Jan 1 2019, In : Neuro-oncology. 21, 1, p. 106-114 9 p.

Research output: Contribution to journal › Article

temozolomide
Glioblastoma
Epidermal Growth Factor Receptor
Multicenter Studies
Safety
3 Citations (Scopus)

Differential response of glioma stem cells to arsenic trioxide therapy is regulated by MNK1 and mRNA translation

Bell, J. B., Eckerdt, F., Dhruv, H. D., Finlay, D., Peng, S., Kim, S., Kroczynska, B., Beauchamp, E. M., Alley, K., Clymer, J., Goldman, S., Cheng, S. Y., James, C. D., Nakano, I., Horbinski, C., Mazar, A. P., Vuori, K., Kumthekar, P., Raizer, J., Berens, M. E. & 1 othersPlatanias, L. C., Jan 1 2018, In : Molecular Cancer Research. 16, 1, p. 32-46 15 p.

Research output: Contribution to journal › Article

MAP Kinase Kinase 1
Protein Biosynthesis
Glioma
Stem Cells
Glioblastoma

Intracranial Response to Anti-Programmed Death 1 Therapy in a Patient with Metastatic Non-Small Cell Lung Cancer with Leptomeningeal Carcinomatosis

Kamath, S. D., Kumthekar, P. U., Kruser, T. J. & Mohindra, N. A., Dec 1 2018, In : Oncologist. 23, 12, p. e159-e161

Research output: Contribution to journal › Article

Meningeal Carcinomatosis
Non-Small Cell Lung Carcinoma
Neoplasm Metastasis
Radiosurgery
Central Nervous System
2 Citations (Scopus)

Medical management of brain metastases and leptomeningeal disease in patients with breast carcinoma

Bowman, K. M. & Kumthekar, P. U., Feb 1 2018, In : Future Oncology. 14, 4, p. 391-407 17 p.

Research output: Contribution to journal › Review article

Breast Neoplasms
Neoplasm Metastasis
Brain
Drug Therapy
Therapeutics