Personal profile

Certifications and Licenses

1996Internship, Saint Francis Hospital, Evanston
1999Residency, Univ. of Iowa Hospitals & Clinics
2003Postdoctoral Fellowship, Baylor College Of Medicine
Neurology

Keywords

  • Stroke
  • Spinocerbellar Ataxia
  • Neurogenetics
  • Ataxia
  • Movement Disorders
  • Genetics - Common Diseases

Fingerprint Fingerprint is based on mining the text of the persons scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 5 Similar Profiles
Spinocerebellar Ataxias Medicine & Life Sciences
Intermediate Filaments Medicine & Life Sciences
Proteins Medicine & Life Sciences
Leucine Medicine & Life Sciences
Nuclear Proteins Medicine & Life Sciences
Genes Medicine & Life Sciences
Neurons Medicine & Life Sciences
Mutation Medicine & Life Sciences

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Research Output 1991 2017

Mutant Ataxin-1 Inhibits Neural Progenitor Cell Proliferation in SCA1

Cvetanovic, M., Hu, Y. S. & Opal, P. Apr 1 2017 In : Cerebellum. 16, 2, p. 340-347 8 p.

Research output: Contribution to journalArticle

Spinocerebellar Ataxias
Stem Cells
Cell Proliferation
Neurogenesis
Cerebral Cortex
6 Citations

Abnormal intermediate filament organization alters mitochondrial motility in giant axonal neuropathy fibroblasts

Lowery, J., Jain, N., Kuczmarski, E. R., Mahammad, S., Goldman, A., Gelfand, V. I., Opal, P. & Goldman, R. D. Feb 15 2016 In : Molecular Biology of the Cell. 27, 4, p. 608-616 9 p.

Research output: Contribution to journalArticle

Giant Axonal Neuropathy
Intermediate Filaments
Fibroblasts
Intermediate Filament Proteins
Ubiquitin-Protein Ligases

Advances in sequencing technologies for understanding hereditary ataxias a review

Didonna, A. & Opal, P. 2016 In : JAMA Neurology. 73, 12, p. 1485-1490 6 p.

Research output: Contribution to journalReview article

Spinocerebellar Degenerations
Technology
Genes
Ataxia
Computational Biology
2 Citations

Intermediate filament aggregates cause mitochondrial dysmotility and increase energy demands in giant axonal neuropathy

Israeli, E., Dryanovski, D. I., Schumacker, P. T., Chandel, N. S., Singer, J. D., Julien, J. P., Goldman, R. D. & Opal, P. Jun 1 2016 In : Human Molecular Genetics. 25, 11, p. 2143-2157 15 p.

Research output: Contribution to journalArticle

Giant Axonal Neuropathy
Intermediate Filaments
Mutation
Cell Shape
Peripheral Nervous System
1 Citations

The role of gigaxonin in the degradation of the glial-specific intermediate filament protein GFAP

Lin, N. H., Huang, Y. S., Opal, P., Goldman, R. D., Messing, A. & Perng, M. D. Dec 15 2016 In : Molecular Biology of the Cell. 27, 25, p. 3980-3990 11 p.

Research output: Contribution to journalArticle

Alexander Disease
Intermediate Filament Proteins
Glial Fibrillary Acidic Protein
Astrocytes
Proteasome Endopeptidase Complex