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Personal profile

Research Interests

Ataxias, spinocerebellar ataxia, movement disorders, neurodegenerative diseases, stroke, cerebrovascular disorders.

Certifications and Licenses


Training Experience

1996Internship, Saint Francis Hospital, Evanston
1999Residency, Univ. of Iowa Hospitals & Clinics
2003Postdoctoral Fellowship, Baylor College Of Medicine

Education/Academic qualification

PhD, Northwestern University Feinberg School of Medicine

… → 1995

MD, University of Poona

… → 1989

Research interests

  • Movement Disorders
  • Neurogenetics
  • Stroke

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  • Research Output

    Purification of prominin-1+ stem cells from postnatal mouse cerebellum

    Edamakanti, C. R. & Opal, P., Apr 2020, In : Journal of Visualized Experiments. 2020, 158, e60554.

    Research output: Contribution to journalArticle

  • Loss of the dystonia gene Thap1 leads to transcriptional deficits that converge on common pathogenic pathways in dystonic syndromes

    Frederick, N. M., Shah, P. V., Didonna, A., Langley, M. R., Kanthasamy, A. G. & Opal, P., Apr 15 2019, In : Human molecular genetics. 28, 8, p. 1343-1356 14 p.

    Research output: Contribution to journalArticle

  • 2 Scopus citations

    Self-assembling vascular endothelial growth factor nanoparticles improve function in spinocerebellar ataxia type 1

    Hu, Y. S., Do, J., Edamakanti, C. R., Kini, A. R., Martina, M., Stupp, S. I. & Opal, P., Feb 1 2019, In : Brain. 142, 2, p. 312-321 10 p.

    Research output: Contribution to journalArticle

  • 3 Scopus citations

    The role of neurofilament aggregation in neurodegeneration: Lessons from rare inherited neurological disorders

    Didonna, A. & Opal, P., May 16 2019, In : Molecular neurodegeneration. 14, 1, 19.

    Research output: Contribution to journalReview article

    Open Access
  • 3 Scopus citations

    ANP32A regulates histone H3 acetylation and promotes leukemogenesis

    Yang, X., Lu, B., Sun, X., Han, C., Fu, C., Xu, K., Wang, M., Li, D., Chen, Z., Opal, P., Wen, Q., Crispino, J. D., Wang, Q. F. & Huang, Z., Jul 1 2018, In : Leukemia. 32, 7, p. 1587-1597 11 p.

    Research output: Contribution to journalArticle

  • 4 Scopus citations