Qiang Zhang

  • 1079 Citations
20002018
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Research Output 2000 2018

  • 1079 Citations
  • 32 Article
  • 2 Review article
2018
10 Citations (Scopus)
Transforming Growth Factors
Prostatic Neoplasms
T-Lymphocytes
Immunotherapy
Antigen Receptors
1 Citation (Scopus)

Impeding circulating tumor cell reseeding decelerates metastatic progression and potentiates chemotherapy

Qian, C., Worrede-Mahdi, A., Shen, F., DiNatale, A., Kaur, R., Zhang, Q., Cristofanilli, M., Meucci, O. & Fatatis, A., Dec 1 2018, In : Molecular Cancer Research. 16, 12, p. 1844-1854 11 p.

Research output: Contribution to journalArticle

Circulating Neoplastic Cells
Drug Therapy
docetaxel
Neoplasms
Breast Neoplasms
2016
11 Citations (Scopus)

Constitutive expression of a dominant-negative TGF-β type II receptor in the posterior left atrium leads to beneficial remodeling of atrial fibrillation substrate

Kunamalla, A., Ng, J., Parini, V., Yoo, S., Mcgee, K. A., Tomson, T. T., Gordon, D., Thorp, E. B., Lomasney, J. W., Zhang, Q., Shah, S. J., Browne, S., Knight, B. P., Passman, R. S., Goldberger, J. J., Aistrup, G. & Arora, R. K., Jun 24 2016, In : Circulation research. 119, 1, p. 69-82 14 p.

Research output: Contribution to journalArticle

Growth Factor Receptors
Transforming Growth Factors
Heart Atria
Atrial Fibrillation
Cardiac Electrophysiologic Techniques
2014
21 Citations (Scopus)

Mysteries of TGF-β paradox in benign and malignant cells

Zhang, Q., Yu, N. & Lee, C., Jan 1 2014, In : Frontiers in Oncology. 4 MAY, 94.

Research output: Contribution to journalArticle

Neoplasms
Organogenesis
Wound Healing
Embryonic Development
Neoplasm Metastasis
12 Citations (Scopus)

Role of the adjacent stroma cells in prostate cancer development and progression: Synergy between TGF-β and IGF signaling

Lee, C., Jia, Z., Rahmatpanah, F., Zhang, Q., Zi, X., McClelland, M. & Mercola, D., Jan 1 2014, In : BioMed Research International. 2014, 502093.

Research output: Contribution to journalReview article

Transforming Growth Factor beta
Prostatic Neoplasms
Stromal Cells
Insulin-Like Growth Factor I
Prostate
2013
7 Citations (Scopus)

Natural products and transforming growth factor-beta (TGF-β) signaling in cancer development and progression

Lee, C., Zhang, Q., Kozlowski, J., Brendler, C., Soares, M. B., Dash, A., Mcclelland, M., Mcclelland, M. & Mercola, D., Nov 27 2013, In : Current Cancer Drug Targets. 13, 5, p. 500-505 6 p.

Research output: Contribution to journalArticle

Biological Products
Transforming Growth Factor beta
Neoplasms
Herbal Medicine
DNA Methylation
27 Citations (Scopus)

α-linolenic acid inhibits human renal cell carcinoma cell proliferation through PPAR-γ activation and COX-2 inhibition

Yang, L., Yuan, J., Liu, L., Shi, C., Wang, L., Tian, F., Liu, F., Wang, H., Shao, C., Zhang, Q., Chen, Z., Qin, W. & Wen, W., Jul 1 2013, In : Oncology Letters. 6, 1, p. 197-202 6 p.

Research output: Contribution to journalArticle

rosiglitazone
Peroxisome Proliferator-Activated Receptors
alpha-Linolenic Acid
Cyclooxygenase 2
Renal Cell Carcinoma
2012
14 Citations (Scopus)

TGF-β mediated DNA methylation in prostate cancer

Lee, C., Zhang, Q., Zi, X., Dash, A., Soares, M. B., Rahmatpanah, F., Jia, Z., McClelland, M. & Mercola, D., Jan 1 2012, In : Translational Andrology and Urology. 1, 2, p. 78-88 11 p.

Research output: Contribution to journalReview article

Transforming Growth Factors
DNA Methylation
Prostatic Neoplasms
Neoplasms
DNA
2011
51 Citations (Scopus)

TGF-β regulates DNA methyltransferase expression in prostate cancer, correlates with aggressive capabilities, and predicts disease recurrence

Zhang, Q., Chen, L., Helfand, B. T., Jang, T. L., Sharma, V., Kozlowski, J., Kuzel, T. M., Zhu, L. J., Yang, X. J., Javonovic, B., Guo, Y., Lonning, S., Harper, J., Teicher, B. A., Brendler, C., Yu, N., Catalona, W. J. & Lee, C., Sep 30 2011, In : PLoS One. 6, 9, e25168.

Research output: Contribution to journalArticle

relapse
methyltransferases
Methyltransferases
prostatic neoplasms
Prostatic Neoplasms
2010
23 Citations (Scopus)

Immunotherapy for human renal cell carcinoma by adoptive transfer of autologous transforming growth factor β-insensitive CD8 + T cells

Wang, L., Wen, W., Yuan, J., Helfand, B., Li, Y., Shi, C., Tian, F., Zheng, J., Wang, F., Chen, L., Liang, L., Zhou, L., Lee, C., Chen, Z., Guo, Y., Wang, H., Zhang, Q. & Qin, W., Jan 1 2010, In : Clinical Cancer Research. 16, 1, p. 164-173 10 p.

Research output: Contribution to journalArticle

Adoptive Transfer
Transforming Growth Factors
Renal Cell Carcinoma
Immunotherapy
T-Lymphocytes
24 Citations (Scopus)

Overexpression of transforming growth factor β1 in malignant prostate cells is partly caused by a runaway of TGF-β1 Auto-induction mediated through a defective recruitment of protein phosphatase 2A by TGF-β type i receptor

Yu, N., Kozlowski, J. M., Park, I. I., Chen, L., Zhang, Q., Xu, D., Doll, J. A., Crawford, S. E., Brendler, C. B. & Lee, C., Jan 1 2010, In : Urology. 76, 6, p. 1519.e8-1519.e13

Research output: Contribution to journalArticle

Homeless Youth
Protein Phosphatase 2
Growth Factor Receptors
Transforming Growth Factors
Prostate
2009
11 Citations (Scopus)

17β-Estradiol at low concentrations acts through distinct pathways in normal versus benign prostatic hyperplasia-derived prostate stromal cells

Park, I. I., Zhang, Q., Liu, V., Kozlowski, J. M., Zhang, J. & Lee, C., Oct 1 2009, In : Endocrinology. 150, 10, p. 4594-4605 12 p.

Research output: Contribution to journalArticle

Prostatic Hyperplasia
Stromal Cells
Prostate
Estradiol
Primary Cell Culture
68 Citations (Scopus)

Nuclear factor-κB-mediated transforming growth factor-β-induced expression of vimentin is an independent predictor of biochemical recurrence after radical prostatectomy

Zhang, Q., Helfand, B. T., Jang, T. L., Zhu, L. J., Chen, L., Yang, X. J., Kozlowski, J., Smith, N., Kundu, S. D., Yang, G., Raji, A. A., Javonovic, B., Pins, M., Lindholm, P., Guo, Y., Catalona, W. J. & Lee, C., May 15 2009, In : Clinical Cancer Research. 15, 10, p. 3557-3567 11 p.

Research output: Contribution to journalArticle

Transforming Growth Factors
Vimentin
Prostatectomy
Epithelial-Mesenchymal Transition
Recurrence
2008
4 Citations (Scopus)

Adoptive Transfer of Tumor-Reactive Transforming Growth Factor-β-Insensitive Cytolytic T Cells for Treatment of Established Mouse Renca Tumors

Qin, W., Tian, F., Wang, F., Song, B., Wang, H., Zhang, Q., Jovanovic, B., Liang, L., Guo, Y., Smith, N. & Lee, C., Oct 1 2008, In : Urology. 72, 4, p. 943-947 5 p.

Research output: Contribution to journalArticle

Adoptive Transfer
Transforming Growth Factors
T-Lymphocytes
Neoplasms
Therapeutics
54 Citations (Scopus)

Cutting edge: TGF-β-induced expression of Foxp3 in T cells is mediated through inactivation of ERK

Luo, X., Zhang, Q., Liu, V., Xia, Z., Pothoven, K. L. & Lee, C., Mar 1 2008, In : Journal of Immunology. 180, 5, p. 2757-2761 5 p.

Research output: Contribution to journalArticle

T-Lymphocytes
decitabine
Epigenomics
Regulatory T-Lymphocytes
Phosphorylation
102 Citations (Scopus)

The toll-like receptor pathway: A novel mechanism of infection-induced carcinogenesis of prostate epithelial cells

Kundu, S. D., Lee, C., Billips, B. K., Habermacher, G. M., Zhang, Q., Liu, V., Wong, L. Y., Klumpp, D. J. & Thumbikat, P., Feb 1 2008, In : Prostate. 68, 2, p. 223-229 7 p.

Research output: Contribution to journalArticle

Toll-Like Receptors
Lipopolysaccharides
Prostate
Carcinogenesis
Epithelial Cells
6 Citations (Scopus)

Treatment of Transforming Growth Factor-Beta-Insensitive Mouse Renca Tumor by Transforming Growth Factor-Beta Elimination

Perry Jr, K. T., Wong, L., Liu, V., Park, I., Zhang, Q., Rejen, V., Huang, X., Smith, N. D., Jovanovic, B., Lonning, S., Teicher, B. A. & Lee, C., Jul 1 2008, In : Urology. 72, 1, p. 225-229 5 p.

Research output: Contribution to journalArticle

Transforming Growth Factor beta
Neoplasms
Therapeutics
Antibodies
Subcutaneous Injections
48 Citations (Scopus)

U19/Eaf2 knockout causes lung adenocarcinoma, B-cell lymphoma, hepatocellular carcinoma and prostatic intraepithelial neoplasia

Xiao, W., Zhang, Q., Habermacher, G., Yang, X. J., Zhang, A. Y., Cai, X., Hahn, J., Liu, J., Pins, M., Doglio, L., Dhir, R., Gingrich, J. & Wang, Z., Mar 6 2008, In : Oncogene. 27, 11, p. 1536-1544 9 p.

Research output: Contribution to journalArticle

Prostatic Intraepithelial Neoplasia
B-Cell Lymphoma
Hepatocellular Carcinoma
Genes
Knockout Mice
6 Citations (Scopus)

Vaccination with transforming growth factor-beta insensitive dendritic cells suppresses pulmonary metastases of renal carcinoma in mice

Tian, F., Wang, L., Qin, W., Wang, F., Song, B., Li, Y., Wen, W., Zhang, Z., Zhu, K., Zhang, Q., Lee, C., Zhong, W., Guo, Y. & Wang, H., Nov 28 2008, In : Cancer Letters. 271, 2, p. 333-341 9 p.

Research output: Contribution to journalArticle

Transforming Growth Factor beta
Dendritic Cells
Vaccination
Neoplasm Metastasis
Carcinoma
2007
14 Citations (Scopus)

TGF-β insensitive dendritic cells: An efficient vaccine for murine prostate cancer

Wang, F. L., Qin, W. J., Wen, W. H., Tian, F., Song, B., Zhang, Q., Lee, C., Zhong, W. D., Guo, Y. L. & Wang, H., Nov 1 2007, In : Cancer Immunology, Immunotherapy. 56, 11, p. 1785-1793 9 p.

Research output: Contribution to journalArticle

Transforming Growth Factor beta
Dendritic Cells
Prostatic Neoplasms
Vaccines
Neoplasms
323 Citations (Scopus)

Tumor evasion of the immune system by converting CD4+CD25 - T cells into CD4+CD25+ T regulatory cells: Role of tumor-derived TGF-β

Liu, V. C., Wong, L. Y., Jang, T., Shah, A. H., Park, I., Yang, X. J., Zhang, Q., Lonning, S., Teicher, B. A. & Lee, C., Mar 1 2007, In : Journal of Immunology. 178, 5, p. 2883-2892 10 p.

Research output: Contribution to journalArticle

Regulatory T-Lymphocytes
Immune System
T-Lymphocytes
Neoplasms
Conditioned Culture Medium
2006
30 Citations (Scopus)

Blockade of transforming growth factor-β signaling in tumor-reactive CD8+ T cells activates the antitumor immune response cycle

Zhang, Q., Yang, X. J., Kundu, S. D., Pins, M., Javonovic, B., Meyer, R., Kim, S. J., Greenberg, N. M., Kuzel, T., Meagher, R., Guo, Y. & Lee, C., Jul 1 2006, In : Molecular Cancer Therapeutics. 5, 7, p. 1733-1743 11 p.

Research output: Contribution to journalArticle

Transforming Growth Factors
T-Lymphocytes
Neoplasms
Heterografts
Prostatic Neoplasms
23 Citations (Scopus)

Infiltration of tumor-reactive transforming growth factor-beta insensitive CD8+ T cells into the tumor parenchyma is associated with apoptosis and rejection of tumor cells

Zhang, Q., Jang, T. L., Yang, X., Park, I., Meyer, R. E., Kundu, S., Pins, M., Javonovic, B., Kuzel, T., Kim, S. J., Van Parijs, L., Smith, N., Wong, L., Greenberg, N. M., Guo, Y. & Lee, C., Feb 15 2006, In : Prostate. 66, 3, p. 235-247 13 p.

Research output: Contribution to journalArticle

Transforming Growth Factor beta
Apoptosis
T-Lymphocytes
Neoplasms
Adoptive Transfer
20 Citations (Scopus)

The leader sequence triggers and enhances several functions of clusterin and is instrumental in the progression of human prostate cancer in vivo and in vitro

Zhang, Q., Zhou, W., Kundu, S. D., Jang, T. L., Yang, X. J., Pins, M., Smith, N., Jovanovic, B., Xin, D., Liang, L., Guo, Y. & Lee, C., Aug 1 2006, In : BJU International. 98, 2, p. 452-460 9 p.

Research output: Contribution to journalArticle

Clusterin
Prostatic Neoplasms
Apoptosis
In Vitro Techniques
Clone Cells
2005
112 Citations (Scopus)

Adoptive transfer of tumor-reactive transforming growth factor-β-insensitive CD8+ T cells: Eradication of autologous mouse prostate cancer

Zhang, Q., Yang, X., Pins, M., Javonovic, B., Kuzel, T., Kim, S. J., Van Parijs, L., Greenberg, N. M., Liu, V., Guo, Y. & Lee, C., Mar 1 2005, In : Cancer Research. 65, 5, p. 1761-1769 9 p.

Research output: Contribution to journalArticle

Adoptive Transfer
Transforming Growth Factors
Prostatic Neoplasms
T-Lymphocytes
Neoplasms
40 Citations (Scopus)

Insensitivity to transforming growth factor-β results from promoter methylation of cognate receptors in human prostate cancer cells (LNCaP)

Zhang, Q., Rubenstein, J. N., Jang, T. L., Pins, M., Javonovic, B., Yang, X. J., Kim, S. J., Park, I. & Lee, C., Sep 1 2005, In : Molecular Endocrinology. 19, 9, p. 2390-2399 10 p.

Research output: Contribution to journalArticle

Transforming Growth Factors
Methylation
Prostatic Neoplasms
decitabine
Prostate
12 Citations (Scopus)

Restoration of expression of transforming growth factor-β Type II receptor in murine renal cell carcinoma (renca) cells by 5-Aza-2′- deoxycytidine

Zhang, Q., Rubenstein, J. N., Liu, V. C., Park, I., Jang, T. & Lee, C., Jan 21 2005, In : Life Sciences. 76, 10, p. 1159-1166 8 p.

Research output: Contribution to journalArticle

decitabine
Transforming Growth Factors
Renal Cell Carcinoma
Restoration
Cells
2002
1 Citation (Scopus)

Renal cell carcinoma related novel gene, GYLZ-RCC18: Cloning and functional studies

Zhang, Q., Chen, L., Liang, L., Xi, Z., Ding, Y., Tong, M., Zhang, Z., Chung, L. & Guo, Y., Jun 17 2002, In : Chinese Medical Journal. 115, 5, p. 746-749 4 p.

Research output: Contribution to journalArticle

Renal Cell Carcinoma
Organism Cloning
Antisense Oligonucleotides
Genes
Transfection
2001

Cloning and functional research of renal cell carcinoma related novel gene - GYLZ-RCC18

Zhang, Q., Chen, L., Junkui, A., Lee, C., Liang, L., Tong, M., Zhang, Z., Na, Y. & Guo, Y., Jan 1 2001, In : Chinese Science Bulletin. 46, 19, p. 1622-1626 5 p.

Research output: Contribution to journalArticle

Renal Cell Carcinoma
Organism Cloning
Research
Antisense Oligonucleotides
Genes

Cloning and identifying renal cell carcinoma differentially expressed genes and their significance

Zhang, Q., Zhang, Z. & Chen, L., Jan 1 2001, In : Zhonghua yi xue za zhi. 81, 6, p. 356-359 4 p.

Research output: Contribution to journalArticle

Renal Cell Carcinoma
Organism Cloning
Genes
Libraries
Complementary DNA
2 Citations (Scopus)

Use of suppression subtractive hybridization strategy for cloning and identifying specifically expressed genes of renal cell carcinoma

Zhang, Q., Zhang, Z., Gong, K., Xin, D., Na, Y. & Guo, Y., Jan 1 2001, In : Chinese Science Bulletin. 46, 3, p. 226-229 4 p.

Research output: Contribution to journalArticle

Renal Cell Carcinoma
Organism Cloning
Genes
Complementary DNA
Clone Cells
2000

Cloning and identifying of renal cell carcinoma differentially expressed genes

Zhang, Q., Zhang, Z., Xin, D., Liang, L., Na, Y. & Guo, Y., Jan 1 2000, In : Zhonghua wai ke za zhi [Chinese journal of surgery]. 38, 12, p. 935-938 4 p.

Research output: Contribution to journalArticle

Renal Cell Carcinoma
Organism Cloning
Libraries
Complementary DNA
Clone Cells
1 Citation (Scopus)

Cloning of renal cell carcinoma relation gene: Construction of a cDNA subtractive library of human renal cell carcinoma and its significance

Zhang, Q., Mao, Z. B., Zhang, Z. W., Xin, D. Q. & Guo, Y. L., Dec 1 2000, In : Progress in Biochemistry and Biophysics. 27, 3, 1 p.

Research output: Contribution to journalArticle

Cloning
Gene Library
Renal Cell Carcinoma
Organism Cloning
Complementary DNA
1 Citation (Scopus)

Mechanisms of drug resistance of primary renal cell carcinomas and their clinical significance

Zhang, Q., Chen, Z. & Shi, Z., Jan 1 2000, In : Zhonghua zhong liu za zhi [Chinese journal of oncology]. 22, 2, p. 145-147 3 p.

Research output: Contribution to journalArticle

Renal Cell Carcinoma
Drug Resistance
Intestinal Neoplasms
Paraffin
Lung Neoplasms