Qing Ching Chen

  • 1423 Citations
1991 …2020

Research output per year

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Research Output

2020

Aggressive morphologic variants of mantle cell lymphoma characterized with high genomic instability showing frequent chromothripsis, CDKN2A/B loss, and TP53 mutations: A multi-institutional study

Streich, L., Sukhanova, M., Lu, X., Chen, Y. H., Venkataraman, G., Mathews, S., Zhang, S., Kelemen, K., Segal, J., Gao, J., Gordon, L., Chen, Q. & Behdad, A., Jan 1 2020, (Accepted/In press) In : Genes Chromosomes and Cancer.

Research output: Contribution to journalArticle

2019
7 Scopus citations
2 Scopus citations

A novel murine model of differentiation-mediated cytomegalovirus reactivation from latently infected bone marrow haematopoietic cells

Liu, X. F., Swaminathan, S., Yan, S., Engelmann, F., Abbott, D. A., VanOsdol, L. A., Heald-Sargent, T., Qiu, L., Chen, Q., Iovane, A., Zhang, Z. & Abecassis, M. M., Dec 1 2019, In : The Journal of general virology. 100, 12, p. 1680-1694 15 p.

Research output: Contribution to journalArticle

1 Scopus citations
Open Access
2 Scopus citations

Rare myeloid sarcoma with KMT2A (MLL)-ELL fusion presenting as a vaginal wall mass

Bao, H., Gao, J., Chen, Y. H., Altman, J. K., Frankfurt, O., Wilson, A. L., Sukhanova, M., Chen, Q. & Lu, X., Mar 28 2019, In : Diagnostic pathology. 14, 1, 26.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Survival outcomes of diffuse large B-cell lymphoma by association with concurrent or antecedent follicular lymphoma and double hit status

Behdad, A., Boddy, C. S., Fought, A. J., Taxter, T., Falkiewicz, M. K., Ayers, E., Chen, Q. C., Chen, Y. H., Karmali, R., Pro, B., Winter, J. N., Landsburg, D. J., Gordon, L. I. & Kaplan, J. B., Nov 10 2019, In : Leukemia and Lymphoma. 60, 13, p. 3266-3271 6 p.

Research output: Contribution to journalArticle

2018

Cutaneous T-Cell Lymphoma, a Novel Manifestation of PDGFRA-Rearranged Neoplasm

Behdad, A., Allen, P., Lu, X., Zhou, X. A., Guitart, J., Chen, Q. & Pro, B., Aug 1 2018, In : American Journal of Dermatopathology. 40, 8, p. 610-613 4 p.

Research output: Contribution to journalArticle

1 Scopus citations
2016

Hepatitis C virus upregulates B-cell receptor signaling: A novel mechanism for HCV-associated B-cell lymphoproliferative disorders

Dai, B., Chen, A. Y., Corkum, C. P., Peroutka, R. J., Landon, A., Houng, S., Muniandy, P. A., Zhang, Y., Lehrmann, E., Mazan-Mamczarz, K., Steinhardt, J., Shlyak, M., Chen, Q. C., Becker, K. G., Livak, F., Michalak, T. I., Talwani, R. & Gartenhaus, R. B., Jun 9 2016, In : Oncogene. 35, 23, p. 2979-2990 12 p.

Research output: Contribution to journalArticle

13 Scopus citations
2015

A novel TTC40-MSI2 fusion in de novo acute myeloid leukemia with an unbalanced 10;17 translocation

Saleki, R., Christensen, T., Liu, W., Wang, X., Chen, Q. C., Aakre, M., Gomes, N. M. V., Alexiev, B. A., Schappert, J., Baer, M. R. & Zou, Y. S., Apr 1 2015, In : Leukemia and Lymphoma. 56, 4, p. 1137-1139 3 p.

Research output: Contribution to journalArticle

6 Scopus citations

Concomitant bone marrow involvement by plasma cell myeloma and primary myelodysplastic syndrome with biclonal complex chromosome anomalies

Nanaji, N. M., Chen, Q. C., Singh, Z., Ross, D. D., Elman, A. H. & Zou, Y. S., Jan 1 2015, In : Leukemia and Lymphoma. 56, 8, p. 2470-2472 3 p.

Research output: Contribution to journalLetter

Concurrent mutations in ATM and genes associated with common γ chain signaling in peripheral T cell lymphoma

Simpson, H. M., Khan, R. Z., Song, C., Sharma, D., Sadashivaiah, K., Furusawa, A., Liu, X., Nagaraj, S., Sengamalay, N., Sadzewicz, L., Tallon, L. J., Chen, Q. C., Livak, F., Rapoport, A. P., Kimball, A. & Banerjee, A., Nov 4 2015, In : PloS one. 10, 11, 141906.

Research output: Contribution to journalArticle

13 Scopus citations

Diseases at the crossroads: Chronic myelogenous leukemia and tuberculosis

Bhatnagar, V., Adelakun, A., Kendall, T., Holtzman, N., Farshidpour, M., Stevenson, B., Chen, Q. & Emadi, A., Jan 1 2015, In : Archives of Iranian Medicine. 18, 1, p. 65-68 4 p.

Research output: Contribution to journalArticle

1 Scopus citations

FDG uptake in liposclerosing myxofibrous tumor causes upstaging of Hodgkin lymphoma

Kim, J., Chen, W., Resnik, C., Dilsizian, V., Chen, Q. & Kimball, A. S., Apr 21 2015, In : Clinical nuclear medicine. 40, 4, p. 325-327 3 p.

Research output: Contribution to journalArticle

Giant cell tumor of the tendon sheath with discordant metabolism as a false positive on staging of mantle cell lymphoma

Rezaee, A., Chen, W., Dilsizian, V., Chen, Q. & Kimball, A. S., Oct 2015, In : Clinical nuclear medicine. 40, 10, p. 814-815 2 p.

Research output: Contribution to journalShort survey

4 Scopus citations

Lack of objective response of myelodysplastic syndromes and acute myeloid leukemia to decitabine after failure of azacitidine

Duong, V. H., Bhatnagar, B., Zandberg, D. P., Vannorsdall, E. J., Tidwell, M. L., Chen, Q. & Baer, M. R., Jan 1 2015, In : Leukemia and Lymphoma. 56, 6, p. 1718-1722 5 p.

Research output: Contribution to journalArticle

10 Scopus citations

RGC-32 is a novel regulator of the T-lymphocyte cell cycle

Tegla, C. A., Cudrici, C. D., Nguyen, V., Danoff, J., Kruszewski, A. M., Boodhoo, D., Mekala, A. P., Vlaicu, S. I., Chen, C., Rus, V., Badea, T. C. & Rus, H., Jun 1 2015, In : Experimental and Molecular Pathology. 98, 3, p. 328-337 10 p.

Research output: Contribution to journalArticle

18 Scopus citations
2014

High frequency of rare structural chromosome abnormalities at relapse of cytogenetically normal acute myeloid leukemia with FLT3 internal tandem duplication

Gourdin, T. S., Zou, Y., Ning, Y., Emadi, A., Duong, V. H., Tidwell, M. L., Chen, C., Rassool, F. V. & Baer, M. R., Oct 1 2014, In : Cancer Genetics. 207, 10-12, p. 467-473 7 p.

Research output: Contribution to journalArticle

7 Scopus citations

Inhibiting CARD11 translation during BCR activation by targeting the eIF4A RNA helicase

Steinhardt, J. J., Peroutka, R. J., Mazan-Mamczarz, K., Chen, Q., Houng, S., Robles, C., Barth, R. N., DuBose, J., Bruns, B., Tesoriero, R., Stein, D., Fang, R., Hanna, N., Pasley, J., Rodriguez, C., Kligman, M. D., Bradley, M., Rabin, J., Shackelford, S., Dai, B. & 4 others, Landon, A. L., Scalea, T., Livak, F. & Gartenhaus, R. B., Dec 11 2014, In : Blood. 124, 25, p. 3758-3767 10 p.

Research output: Contribution to journalArticle

7 Scopus citations

Ten-day decitabine as initial therapy for newly diagnosed patients with acute myeloid leukemia unfit for intensive chemotherapy

Bhatnagar, B., Duong, V. H., Gourdin, T. S., Tidwell, M. L., Chen, C., Ning, Y., Emadi, A., Sausville, E. A. & Baer, M. R., Jan 1 2014, In : Leukemia and Lymphoma. 55, 7, p. 1533-1537 5 p.

Research output: Contribution to journalArticle

32 Scopus citations
2013

Natural autoantibodies and associated B cells in immunity and autoimmunity

Mannoor, K., Xu, Y. & Chen, C., Feb 18 2013, In : Autoimmunity. 46, 2, p. 138-147 10 p.

Research output: Contribution to journalReview article

29 Scopus citations

Schistocytes, echinocytes, iron deficiency anemia, and thrombocytopenia - Hematologic manifestations of splenic angiosarcoma

Rosenblatt, P., Koka, R., Chen, Q., Papadimitriou, J. C., Sausville, E. A. & Emadi, A., Oct 1 2013, In : Archives of Iranian Medicine. 16, 10, p. 602-605 4 p.

Research output: Contribution to journalArticle

2 Scopus citations

Symptomatic response to imatinib mesylate in cutaneous mastocytosis associated with chronic myelomonocytic leukemia

Vannorsdall, E. J., Collins, J. A., Chen, Q. C., Sarai, G. & Baer, M. R., Aug 13 2013, In : Current Oncology. 20, 4

Research output: Contribution to journalArticle

4 Scopus citations

Unbalanced 11;18 translocation in an acute erythroid leukemia after radioactive iodine therapy

Trikalinos, N. A., Chen, Q., Ning, Y., Sausville, E. A. & Baer, M. R., Jun 1 2013, In : Cancer Genetics. 206, 6, p. 252-255 4 p.

Research output: Contribution to journalArticle

4 Scopus citations
2012

Expression of natural autoantibodies in MRL-lpr mice protects from lupus nephritis and improves survival

Mannoor, K., Matejuk, A., Xu, Y., Beardall, M. & Chen, C., Apr 15 2012, In : Journal of Immunology. 188, 8, p. 3628-3638 11 p.

Research output: Contribution to journalArticle

27 Scopus citations

IL-21 promotes lupus-like disease in chronic graft-versus-host disease through both CD4 T cell- and b cell-intrinsic mechanisms

Nguyen, V., Luzina, I., Rus, H., Tegla, C., Chen, C. & Rus, V., Jul 15 2012, In : Journal of Immunology. 189, 2, p. 1081-1093 13 p.

Research output: Contribution to journalArticle

23 Scopus citations

Pathogenesis of early leukemia and lymphoma

Zhao, X. F., Reitz, M., Chen, Q. C. & Stass, S., Mar 1 2012, Translational Pathology of Early Cancer. IOS Press, p. 341-374 34 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2011

Activation of a novel palmitoyltransferase ZDHHC14 in acute biphenotypic leukemia and subsets of acute myeloid leukemia

Yu, L., Reader, J. C., Chen, C., Zhao, X. F., Ha, J. S., Lee, C., York, T., Gojo, I., Baer, M. R. & Ning, Y., Feb 2011, In : Leukemia. 25, 2, p. 367-371 5 p.

Research output: Contribution to journalLetter

24 Scopus citations

Intra-golgi formation of IgM-glycosaminoglycan complexes promotes Ig deposition

Khan, S. N., Cox, J. V., Nishimoto, S. K., Chen, C., Fritzler, M. J., Hendershot, L. M., Weigert, M. & Radic, M., Sep 15 2011, In : Journal of Immunology. 187, 6, p. 3198-3207 10 p.

Research output: Contribution to journalArticle

3 Scopus citations

Microarray detection of multiple recurring submicroscopic chromosomal aberrations in pediatric T-cell acute lymphoblastic leukemia

Yu, L., Slovak, M. L., Mannoor, K., Chen, C., Hunger, S. P., Carroll, A. J., Schultz, R. A., Shaffer, L. G., Ballif, B. C. & Ning, Y., Jun 1 2011, In : Leukemia. 25, 6, p. 1042-1046 5 p.

Research output: Contribution to journalArticle

15 Scopus citations

Pathogenesis of early leukemia and lymphoma

Zhao, X. F., Reitz, M., Chen, Q. C. & Stass, S., Dec 12 2011, In : Cancer Biomarkers. 9, 1-6, p. 341-374 34 p.

Research output: Contribution to journalArticle

5 Scopus citations
2009

Exclusion of natural autoantibody-producing B cells from IgG memory B cell compartment during T cell-dependent immune responses

Matejuk, A., Beardall, M., Xu, Y., Tian, Q., Phillips, D., Alabyev, B., Mannoor, K. & Chen, C., Jun 15 2009, In : Journal of Immunology. 182, 12, p. 7634-7643 10 p.

Research output: Contribution to journalArticle

16 Scopus citations
2008

Editing and escape from editing in anti-DNA B cells

Khan, S. N., Witsch, E. J., Goodman, N. G., Panigrahi, A. K., Chen, C., Jiang, Y., Cline, A. M., Erikson, J., Weigert, M., Luning Prak, E. T. & Radic, M., Mar 25 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 10, p. 3861-3866 6 p.

Research output: Contribution to journalArticle

19 Scopus citations

Primary gastric T cell lymphoma mimicking marginal zone B cell lymphoma of mucosa-associated lymphoid tissue

Holanda, D., Zhao, M. Y., Rapoport, A. P., Garofalo, M., Chen, Q. & Frank Zhao, X., May 20 2008, In : Journal of Hematopathology. 1, 1, p. 29-35 7 p.

Research output: Contribution to journalArticle

10 Scopus citations
2006

B cells expressing a natural polyreactive autoantibody have a distinct phenotype and are overrepresented in immunoglobulin heavy chain transgenic mice

Tian, Q., Beardall, M., Xu, Y., Li, J., Parker, D. C., Casanova, N., Bakke, A. C. & Chen, C., Aug 15 2006, In : Journal of Immunology. 177, 4, p. 2412-2422 11 p.

Research output: Contribution to journalArticle

6 Scopus citations

Selection of anti-double-stranded DNA B cells in autoimmune MRL-lpr/lpr mice

Chen, C., Li, H., Tian, Q., Beardall, M., Xu, Y., Casanova, N. & Weigert, M., May 1 2006, In : Journal of Immunology. 176, 9, p. 5183-5190 8 p.

Research output: Contribution to journalArticle

30 Scopus citations
1998

Intranuclear cytoplasmic inclusions in the differential diagnosis of papillary thyroid carcinoma and bronchioloalveolar carcinoma.

Chen, C., Hoda, R. S. & Hoda, S. A., Jan 1 1998, In : Diagnostic Cytopathology. 18, 5, p. 384-386 3 p.

Research output: Contribution to journalLetter

1 Scopus citations
1997

Editing disease-associated autoantibodies

Chen, C., Prak, E. L. & Weigert, M., Jan 1 1997, In : Immunity. 6, 1, p. 97-105 9 p.

Research output: Contribution to journalArticle

187 Scopus citations
1996

Tolerance to single, but not multiple, amino acid replacements in antibody V H CDR2: A means of minimizing B cell wastage from somatic hypermutation?

Brown, M., Rittenberg, M. B., Chen, C. & Roberts, V. A., May 1 1996, In : Journal of Immunology. 156, 9, p. 3285-3291 7 p.

Research output: Contribution to journalArticle

15 Scopus citations
1995

Enhancement and destruction of antibody function by somatic mutation: Unequal occurrence is controlled by V gene combinatorial associations

Chen, C., Roberts, V. A., Stevens, S., Brown, M., Stenzel-Poore, M. P. & Rittenberg, M. B., Jan 1 1995, In : EMBO Journal. 14, 12, p. 2784-2794 11 p.

Research output: Contribution to journalArticle

40 Scopus citations

Immunoglobulin heavy chain gene replacement: A mechanism of receptor editing

Chen, C., Nagy, Z., Luning Prak, E. & Weigert, M., Jan 1 1995, In : Immunity. 3, 6, p. 747-755 9 p.

Research output: Contribution to journalArticle

264 Scopus citations

The site and stage of anti-DNA B-cell deletion

Chen, C., Nagy, Z., Weigert, M., Radic, M. Z., Hardys, R. R., Huszari, D. & Camper, S. A., Jan 19 1995, In : Nature. 373, 6511, p. 252-255 4 p.

Research output: Contribution to journalLetter

255 Scopus citations
1994

Defective secretion of an immtmoglobulln caused by mutations in the heavy chain complementarity determining region 2

Chen, C., Martin, T. M., Stevens, S. & Rittenberg, M. B., Aug 1 1994, In : Journal of Experimental Medicine. 180, 2, p. 577-586 10 p.

Research output: Contribution to journalArticle

28 Scopus citations

Deletion and editing of B cells that express antibodies to DNA

Chen, C., Radic, M. Z., Erikson, J., Camper, S. A., Litwin, S., Hardy, R. R. & Weigert, M., Feb 15 1994, In : Journal of Immunology. 152, 4, p. 1970-1982 13 p.

Research output: Contribution to journalArticle

148 Scopus citations
1992

Generation and analysis of random point mutations in an antibody CDR2 sequence: Many mutated antibodies lose their ability to bind antigen

Chen, C., Roberts, V. A. & Rittenberg, M. B., Sep 1 1992, In : Journal of Experimental Medicine. 176, 3, p. 855-866 12 p.

Research output: Contribution to journalArticle

60 Scopus citations

The developmental patterns of B cell precursors distinguishing between environmental and nonenvironmental forms of phosphocholine

Chen, C., Bruderer, U. & Rittenberg, M. B., Sep 1992, In : Cellular Immunology. 143, 2, p. 378-388 11 p.

Research output: Contribution to journalArticle

4 Scopus citations
1991

Natural auto- and polyreactive antibodies differing from antigen-induced antibodies in the H chain CDR3

Chen, C., Stenzel-Poore, M. P. & Rittenberg, M. B., Oct 1 1991, In : Journal of Immunology. 147, 7, p. 2359-2367 9 p.

Research output: Contribution to journalArticle

79 Scopus citations