Qing Fan

  • 1286 Citations
20002019
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Personal profile

Research Interests

My research interest lies in identification and characterization of cell surface carbohydrates and proteins required for herpes simplex virus (HSV) viral entry and cell fusion. I have been focusing on glycoprotein B (gB) and gL, two of four glycoproteins essential for HSV entry and cell fusion. I have been studying the interaction between gB and gB entry receptor, paired immunoglobulin like-type 2 receptor (PILRa). I am also interested in the interactions among gB, gD, gH and gL.

Education/Academic qualification

PhD, Chinese Academy of Sciences

… → 1998

Keywords

  • Virology

Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

Anabaena Medicine & Life Sciences
Glycoproteins Medicine & Life Sciences
Human herpesvirus 1 Agriculture & Biology
Human Herpesvirus 1 Medicine & Life Sciences
Cyanobacteria Medicine & Life Sciences
glycoproteins Agriculture & Biology
biological control Agriculture & Biology
Mutation Medicine & Life Sciences

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Grants 2013 2019

Research Output 2000 2018

  • 1286 Citations
  • 46 Article
  • 1 Conference contribution

Natural selection of glycoprotein B mutations that rescue the small-plaque phenotype of a fusion-impaired herpes simplex virus mutant

Fan, Q., Kopp, S. J., Byskosh, N. C., Connolly, S. A. & Longnecker, R. M., Sep 1 2018, In : mBio. 9, 5, e01948-18.

Research output: Contribution to journalArticle

Genetic Selection
Simplexvirus
Glycoproteins
Phenotype
Mutation
2 Citations (Scopus)
Human Herpesvirus 1
Glycoproteins
Immunoglobulins
INDEL Mutation
Oncolytic Viruses
8 Citations (Scopus)

Role of two cell wall amidases in septal junction and nanopore formation in the multicellular cyanobacterium Anabaena sp. PCC 7120

Bornikoel, J., Carrión, A., Fan, Q., Flores, E., Forchhammer, K., Mariscal, V., Mullineaux, C. W., Perez, R., Silber, N., Peter Wolk, C. & Maldener, I., Sep 5 2017, In : Frontiers in Cellular and Infection Microbiology. 7, SEP, 386.

Research output: Contribution to journalArticle

Nanopores
Anabaena
Cyanobacteria
amidase
Nostoc
4 Citations (Scopus)

Structure-based mutations in the herpes simplex virus 1 glycoprotein B ectodomain arm impart a slow-entry phenotype

Fan, Q., Kopp, S. J., Connolly, S. A. & Longnecker, R. M., May 1 2017, In : mBio. 8, 3, e00614-17.

Research output: Contribution to journalArticle

Glycoproteins
Phenotype
Mutation
Herpesviridae
Cercopithecine Herpesvirus 1
10 Citations (Scopus)
Human herpesvirus 1
chimerism
Human Herpesvirus 1
glycoproteins
Saimiriine herpesvirus 1