Grants per year
Personal profile
Research Interests
Dr. Kumar has worked as an academic allergist at Lurie Children's for over 18 years. He has a number of research interests. Most prominently he is interested in the prenatal and early life exposures, which in combination with genetic factors are associated with the development of early childhood wheezing, atopic disease and asthma. Dr. Kumar also has interests in a number of other areas including:the determinants of lung function from childhood into later adult life (CARDIA study), development of food allergy in early infancy, and validation of PROMIS instruments in asthma (AAD-PEPR study). Additionally, he serves as the site-PI for a consortium which evaluates personalized medicine approaches for severe asthma.
Dr. Kumar's research is focused on prenatal and early life exposures, which in combination with genetic factors are associated with the development of early childhood wheezing, asthma, and allergic disease. In particular, differentially distributed risk factors and differentially distributed genetic factors may contribute to asthma health disparities in inner city populations. In terms of differentially distributed genetic factors, we have focused on the role of ancestry in modulating phenotypes such as plateau lung function. We also have evaluated the role of racially differentially distributed early life factors on the development of associated phenotypes including atopy. Our research in these areas has been published in a number of journals including the Journal of Allergy and Clinical Immunology, Clinical and Experimental Allergy, and The New England Journal of Medicine. Dr. Kumar also has interests in a number of other areas including:the determinants of lung function from childhood into later adult life (CARDIA study), development of food allergy in early infancy, and validation of PROMIS instruments in asthma (AAD-PEPR study). Additionally, he serves as the site-PI for a consortium which evaluates personalized medicine approaches for severe asthma.
Dr. Kumar's clinical focus complements my research profile with a focus on provision of asthma care to inner city families. With over a decade of experience in this area, we provide family centered multidisciplinary care in this population. Dr. Kumar also oversees a clinic which looks to implement guidelines for assessment of peanut allergy in the first 4-6 months of life and early peanut introduction. As an allergist in a tertiary care referral center of excellence, he also has extensive experience in management of other allergic diseases including food allergy, rhinitis, eczema and drug allergy. Dr. Kumar serves as the clinical practice director for the Division of Allergy and Clinical Immunology at Lurie Children's Hospital.
Certifications and Licenses
Allergy & Immunology |
Training Experience
1993 | Internship, Charles Camsell Provincial General Hospital, Canada |
1997 | Residency, Children's Hospital, Winnipeg |
1999 | Fellowship, Children's Hospital, Winnipeg |
Education/Academic qualification
MD, Medicine, University of Alberta
… → 1992
Research interests keywords
- Asthma
- Food Allergy
- Genomics
- Health Disparities
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Collaborations and top research areas from the last five years
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Mechanisms for initiation of food allergy early in life
Kumar, R. (PD/PI)
Indiana University, National Institute of Allergy and Infectious Diseases
7/1/20 → 6/30/25
Project: Research project
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MILES: A double-blind, placebo controlled randomized trial to study Viaskin Milk Efficacy and Safety for treating IgE-Mediated Cow's Milk Allergy in Children (MILES Study)
Makhija, M. M. (PD/PI), Kumar, R. (Co-Investigator), Pongracic, J. A. (Co-Investigator) & Robison, R. G. (Co-Investigator)
10/1/15 → 8/31/50
Project: Research project
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The Airway Functional Genomics of Bronchodilator Drug Response in Minority Children with Asthma
Kumar, R. (PD/PI)
University of California at San Francisco, National Heart, Lung, and Blood Institute
8/1/19 → 6/30/20
Project: Research project
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Data, Modeling, and Coordination Center for PrecISE Network
Kumar, R. (PD/PI) & Makhija, M. M. (PD/PI)
University of North Carolina at Chapel Hill, National Heart, Lung, and Blood Institute
7/1/19 → 6/30/21
Project: Research project
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Natural History of Viral Induced Airway Dysfunction and Asthma in Minority Children
Kumar, R. (PD/PI)
University of California San Francisco, National Heart, Lung, and Blood Institute
9/24/18 → 7/31/19
Project: Research project
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5-HTP inhibits eosinophilia via intracellular endothelial 5-HTRs; SNPs in 5-HTRs associate with asthmatic lung function
Walker, M. T., Bloodworth, J. C., Kountz, T. S., McCarty, S. L., Green, J. E., Ferrie, R. P., Campbell, J. A., Averill, S. H., Beckman, K. B., Grammer, L. C., Eng, C., Avila, P. C., Farber, H. J., Rodriguez-Cintron, W., Rodriguez-Santana, J. R., Serebrisky, D., Thyne, S. M., Seibold, M. A., Burchard, E. G. & Kumar, R. & 1 others, , 2024, In: Frontiers in Allergy. 5, 1385168.Research output: Contribution to journal › Article › peer-review
Open Access -
The Association of Periconception Asthma Medication Discontinuation with Adverse Obstetric Outcomes
Rohn, M. C. H., Stevens, D. R., Grobman, W. A., Kumar, R., Chen, Z., Deshane, J., Biggio, J. R., Subramaniam, A., Grantz, K. L., Sherman, S. & Mendola, P., May 28 2024, In: American journal of perinatology. 41, p. E2089-E2097Research output: Contribution to journal › Article › peer-review
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Validation of human telomere length multi-ancestry meta-analysis association signals identifies POP5 and KBTBD6 as human telomere length regulation genes
Keener, R., Chhetri, S. B., Connelly, C. J., Taub, M. A., Conomos, M. P., Weinstock, J., Ni, B., Strober, B., Aslibekyan, S., Auer, P. L., Barwick, L., Becker, L. C., Blangero, J., Bleecker, E. R., Brody, J. A., Cade, B. E., Celedon, J. C., Chang, Y. C., Cupples, L. A. & Custer, B. & 78 others, , Dec 2024, In: Nature communications. 15, 1, 4417.Research output: Contribution to journal › Article › peer-review
Open Access -
Asthma Medication Regimens in Pregnancy: Longitudinal Changes in Asthma Status
Rohn, M. C. H., Stevens, D. R., Kanner, J., Nobles, C., Chen, Z., Grantz, K. L., Sherman, S., Grobman, W. A., Kumar, R., Biggio, J. & Mendola, P., Jan 1 2023, In: American journal of perinatology. 40, 2, p. 172-180 9 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Coordinated Health Care Interventions for Childhood Asthma Gaps in Outcomes (CHICAGO) plan
CHICAGO Plan Consortium, Aug 2023, In: Journal of Allergy and Clinical Immunology: Global. 2, 3, 100100.Research output: Contribution to journal › Article › peer-review
Open Access
Datasets
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Fetal cord blood and tissue immune responses to chronic placental inflammation and chorioamnionitis
Singh, A. M. (Creator), Sherenian, M. G. (Creator), Kim, K.-Y. (Creator), Erickson, K. A. (Creator), Yang, A. (Creator), Mestan, K. (Creator), Ernst, L. M. (Creator) & Kumar, R. (Creator), figshare, 2018
DOI: 10.6084/m9.figshare.c.4305842, https://springernature.figshare.com/collections/Fetal_cord_blood_and_tissue_immune_responses_to_chronic_placental_inflammation_and_chorioamnionitis/4305842
Dataset
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Additional file 1: of Correction to: Dual RNA-seq reveals viral infections in asthmatic children without respiratory illness which are associated with changes in the airway transcriptome
Wesolowska-Andersen, A. (Creator), Everman, J. L. (Creator), Davidson, R. (Creator), Rios, C. (Creator), Herrin, R. (Creator), Eng, C. (Creator), Janssen, W. J. (Creator), Liu, A. H. (Creator), Oh, S. S. (Creator), Kumar, R. (Creator), Fingerlin, T. E. (Creator), Rodriguez-Santana, J. (Creator), Burchard, E. G. (Creator) & Seibold, M. A. (Creator), figshare, 2018
DOI: 10.6084/m9.figshare.6125912, https://springernature.figshare.com/articles/dataset/Additional_file_1_of_Correction_to_Dual_RNA-seq_reveals_viral_infections_in_asthmatic_children_without_respiratory_illness_which_are_associated_with_changes_in_the_airway_transcriptome/6125912
Dataset
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Correction to: Dual RNA-seq reveals viral infections in asthmatic children without respiratory illness which are associated with changes in the airway transcriptome
Wesolowska-Andersen, A. (Creator), Everman, J. L. (Creator), Davidson, R. (Creator), Rios, C. (Creator), Herrin, R. (Creator), Eng, C. (Creator), Janssen, W. J. (Creator), Liu, A. H. (Creator), Oh, S. S. (Creator), Kumar, R. (Creator), Fingerlin, T. E. (Creator), Rodriguez-Santana, J. (Creator), Burchard, E. G. (Creator) & Seibold, M. A. (Creator), figshare, 2018
DOI: 10.6084/m9.figshare.c.4065521, https://springernature.figshare.com/collections/Correction_to_Dual_RNA-seq_reveals_viral_infections_in_asthmatic_children_without_respiratory_illness_which_are_associated_with_changes_in_the_airway_transcriptome/4065521
Dataset