Grants per year
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Fullerenes
Chemical Compounds
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Chemical Compounds
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Medicine & Life Sciences
fullerenes
Physics & Astronomy
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Medicine & Life Sciences
Hydrocarbons
Chemical Compounds
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Medicine & Life Sciences
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Grants 2012 2020
Discovery of novel small molecule antidepressants
Clutter, M., Mishra, R. K. & Schiltz, G. E.
Vanderbilt University, National Institute of Mental Health
2/1/18 → 1/31/20
Project: Research project
Antidepressive Agents
High-Throughput Screening Assays
Manuscripts
Organized Financing
Research
Targeting EZH2 in castration-resistant prostate cancer
Mishra, R. K. & Schiltz, G. E.
U.S. Army Medical Research and Materiel Command
8/1/17 → 7/31/20
Project: Research project
Astemizole
Castration
Nuclear Factor 90 Proteins
Prostatic Neoplasms
Zinc Compounds
RHLCCC: Medicinal & Synthetic Chemistry Core
Mishra, R. K., Scheidt, K. A. & Schiltz, G. E.
8/1/16 → 7/31/18
Project: Research project
Discovery of novel small molecule antidepressants
Chetkovich, D. M., Clutter, M., Han, Y., Luan, C., Mishra, R. K. & Schiltz, G. E.
National Institute of Mental Health
4/15/16 → 1/31/19
Project: Research project
Cyclic Nucleotides
Antidepressive Agents
Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels
Major Depressive Disorder
Fluorescence Polarization
Subproject for Gary Schiltz for the project titled, "Discovery of novel small molecule antidepressants".
Clutter, M., Luan, C., Mishra, R. K. & Schiltz, G. E.
National Institute of Mental Health
4/15/16 → 1/31/19
Project: Research project
Cyclic Nucleotides
Antidepressive Agents
Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels
Major Depressive Disorder
Fluorescence Polarization
Research Output 1988 2019
Discovery of a novel class of potent and selective tetrahydroindazole-based sigma-1 receptor ligands
Iyamu, I. D., Lv, W., Malik, N., Mishra, R. K. & Schiltz, G. E., May 1 2019, In : Bioorganic and Medicinal Chemistry. 27, 9, p. 1824-1835 12 p.Research output: Contribution to journal › Article
Protein Transport
Ligands
Molecular modeling
Central Nervous System Diseases
Structure-Activity Relationship
1
Citation
(Scopus)
Discovery of covalent enzyme inhibitors using virtual docking of covalent fragments
Chowdhury, S. R., Kennedy, S., Zhu, K., Mishra, R. K., Chuong, P., Nguyen, A. U., Kathman, S. G. & Statsyuk, A. V., Jan 1 2019, In : Bioorganic and Medicinal Chemistry Letters. 29, 1, p. 36-39 4 p.Research output: Contribution to journal › Article
Cysteine Proteinase Inhibitors
Cathepsin L
Cathepsin B
Enzyme Inhibitors
Peptide Hydrolases
Synthesis and Biological Evaluation of 3-Arylindazoles as Selective MEK4 Inhibitors
Deibler, K. K., Schiltz, G. E., Clutter, M., Mishra, R. K., Vagadia, P. P., O'Connor, M., George, M. D., Gordon, R., Fowler, G., Bergan, R. & Scheidt, K. A., Mar 22 2019, In : ChemMedChem. 14, 6, p. 615-620 6 p.Research output: Contribution to journal › Article
MAP Kinase Kinase 4
Benzoic Acid
Molecular modeling
Oncology
p38 Mitogen-Activated Protein Kinases
Selective disruption of TLR2/MyD88 interaction inhibits inflammation and attenuates Alzheimer's pathology
Rangasamy, S. B., Jana, M., Roy, A., Corbett, G. T., Kundu, M., Chandra, S., Mondal, S., Dasarathi, S., Mufson, E. J., Mishra, R. K., Luan, C-H., Bennett, D. A. & Pahan, K., Jul 10 2018, In : The Journal of clinical investigation.Research output: Contribution to journal › Article
Pathology
Inflammation
Peptides
Alzheimer Disease
Hippocampus
5
Citations
(Scopus)
Targeting Processive Transcription Elongation via SEC Disruption for MYC-Induced Cancer Therapy
Liang, K., Smith, E., Aoi, Y., Stoltz, K. L., Katagi, H., Woodfin, A. R., Rendleman, E. J., Marshall, S. A., Murray, D. C., Wang, L., Ozark, P. A., Mishra, R. K., Hashizume, R., Schiltz, G. E. & Shilatifard, A., Oct 18 2018, In : Cell. 175, 3, p. 766-779.e17Research output: Contribution to journal › Article
Transcription
Elongation
Positive Transcriptional Elongation Factor B
Neoplasms
Peptidomimetics