Grants per year
Personal profile
Education/Academic qualification
PhD, Sambalpur University
… → 2006
Fingerprint Dive into the research topics where Rama K Mishra is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Fullerenes
Chemical Compounds
Molecules
Chemical Compounds
Quantitative Structure-Activity Relationship
Medicine & Life Sciences
Ligands
Medicine & Life Sciences
Phosphotransferases
Chemical Compounds
Hydrocarbons
Chemical Compounds
Hemagglutinins
Medicine & Life Sciences
Polynomials
Chemical Compounds
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Grants 2012 2024
Development of Novel MNK Inhibitors for Treating Glioblastoma
Clutter, M., Eckerdt, F. D., Horbinski, C. M., James, C. D., Mishra, R. K., Platanias, L. C. & Schiltz, G. E.
National Institute of Neurological Disorders and Stroke
9/1/19 → 6/30/24
Project: Research project
Glioblastoma
Stem Cells
Phosphotransferases
Cell Survival
Survival
Identification of small molecule inhibitors of Plek2 for the treatment of myeloproliferative neoplasms
University Hospitals Health System
1/1/19 → 12/31/20
Project: Research project
Neoplasms
Therapeutics
Bone Marrow Diseases
Mutation
Hematopoiesis
Discovery of novel small molecule antidepressants
Clutter, M., Mishra, R. K. & Schiltz, G. E.
Vanderbilt University, National Institute of Mental Health
2/1/18 → 1/31/20
Project: Research project
Antidepressive Agents
High-Throughput Screening Assays
Manuscripts
Organized Financing
Research
Targeting EZH2 in castration-resistant prostate cancer
Mishra, R. K. & Schiltz, G. E.
U.S. Army Medical Research and Materiel Command
8/1/17 → 7/31/20
Project: Research project
Astemizole
Castration
Nuclear Factor 90 Proteins
Prostatic Neoplasms
Zinc Compounds
RHLCCC: Medicinal & Synthetic Chemistry Core
Mishra, R. K., Scheidt, K. A. & Schiltz, G. E.
8/1/16 → 7/31/18
Project: Research project
Research Output 1988 2019
Development of Tetrahydroindazole-Based Potent and Selective Sigma-2 Receptor Ligands
Iyamu, I. D., Lv, W., Malik, N., Mishra, R. K. & Schiltz, G. E., Jul 3 2019, In : ChemMedChem. 14, 13, p. 1248-1256 9 p.Research output: Contribution to journal › Article
Drug Discovery
Ligands
Central Nervous System Diseases
Neurology
Solubility
2
Citations
(Scopus)
Discovery of a novel class of potent and selective tetrahydroindazole-based sigma-1 receptor ligands
Iyamu, I. D., Lv, W., Malik, N., Mishra, R. K. & Schiltz, G. E., May 1 2019, In : Bioorganic and Medicinal Chemistry. 27, 9, p. 1824-1835 12 p.Research output: Contribution to journal › Article
Protein Transport
Ligands
Molecular modeling
Central Nervous System Diseases
Structure-Activity Relationship
2
Citations
(Scopus)
Discovery of covalent enzyme inhibitors using virtual docking of covalent fragments
Chowdhury, S. R., Kennedy, S., Zhu, K., Mishra, R. K., Chuong, P., Nguyen, A. U., Kathman, S. G. & Statsyuk, A. V., Jan 1 2019, In : Bioorganic and Medicinal Chemistry Letters. 29, 1, p. 36-39 4 p.Research output: Contribution to journal › Article
Cysteine Proteinase Inhibitors
Cathepsin L
Cathepsin B
Enzyme Inhibitors
Peptide Hydrolases
Discovery of novel Mnk inhibitors using mutation-based induced-fit virtual high-throughput screening
Mishra, R. K., Clutter, M. R., Blyth, G. T., Kosciuczuk, E. M., Blackburn, A. Z., Beauchamp, E. M., Schiltz, G. E. & Platanias, L. C., Oct 1 2019, In : Chemical Biology and Drug Design. 94, 4, p. 1813-1823 11 p.Research output: Contribution to journal › Article
Screening
Phosphotransferases
Throughput
Acute Myeloid Leukemia
Mutation
Modeling MEK4 Kinase Inhibitors through Perturbed Electrostatic Potential (ESP) Charges
Mishra, R. K., Deibler, K. K., Clutter, M. R., Vagadia, P. P., O'Connor, M., Schiltz, G. E., Bergan, R. & Scheidt, K. A., Jan 1 2019, (Accepted/In press) In : Journal of Chemical Information and Modeling.Research output: Contribution to journal › Article
Electrostatics
activity structure
Phosphotransferases
non-alignment
predictive model