Rama K Mishra

  • 1307 Citations
1988 …2020
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  • 2 Similar Profiles
Fullerenes Chemical Compounds
Molecules Chemical Compounds
Quantitative Structure-Activity Relationship Medicine & Life Sciences
Ligands Medicine & Life Sciences
fullerenes Physics & Astronomy
Hydrocarbons Chemical Compounds
Hemagglutinins Medicine & Life Sciences
Polynomials Chemical Compounds

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Grants 2012 2020

Neoplasms
Therapeutics
Bone Marrow Diseases
Mutation
Hematopoiesis
Antidepressive Agents
High-Throughput Screening Assays
Manuscripts
Organized Financing
Research
Astemizole
Castration
Nuclear Factor 90 Proteins
Prostatic Neoplasms
Zinc Compounds
Cyclic Nucleotides
Antidepressive Agents
Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels
Major Depressive Disorder
Fluorescence Polarization

Research Output 1988 2019

  • 1307 Citations
  • 64 Article
  • 1 Comment/debate
  • 1 Editorial
  • 1 Review article

Development of Tetrahydroindazole-Based Potent and Selective Sigma-2 Receptor Ligands

Iyamu, I. D., Lv, W., Malik, N., Mishra, R. K. & Schiltz, G. E., Jul 3 2019, In : ChemMedChem. 14, 13, p. 1248-1256 9 p.

Research output: Contribution to journalArticle

Drug Discovery
Ligands
Central Nervous System Diseases
Neurology
Solubility
2 Citations (Scopus)

Discovery of a novel class of potent and selective tetrahydroindazole-based sigma-1 receptor ligands

Iyamu, I. D., Lv, W., Malik, N., Mishra, R. K. & Schiltz, G. E., May 1 2019, In : Bioorganic and Medicinal Chemistry. 27, 9, p. 1824-1835 12 p.

Research output: Contribution to journalArticle

Protein Transport
Ligands
Molecular modeling
Central Nervous System Diseases
Structure-Activity Relationship
2 Citations (Scopus)

Discovery of covalent enzyme inhibitors using virtual docking of covalent fragments

Chowdhury, S. R., Kennedy, S., Zhu, K., Mishra, R. K., Chuong, P., Nguyen, A. U., Kathman, S. G. & Statsyuk, A. V., Jan 1 2019, In : Bioorganic and Medicinal Chemistry Letters. 29, 1, p. 36-39 4 p.

Research output: Contribution to journalArticle

Cysteine Proteinase Inhibitors
Cathepsin L
Cathepsin B
Enzyme Inhibitors
Peptide Hydrolases

Synthesis and Biological Evaluation of 3-Arylindazoles as Selective MEK4 Inhibitors

Deibler, K. K., Schiltz, G. E., Clutter, M., Mishra, R. K., Vagadia, P. P., O'Connor, M., George, M. D., Gordon, R., Fowler, G., Bergan, R. & Scheidt, K. A., Mar 22 2019, In : ChemMedChem. 14, 6, p. 615-620 6 p.

Research output: Contribution to journalArticle

MAP Kinase Kinase 4
Benzoic Acid
Molecular modeling
Oncology
p38 Mitogen-Activated Protein Kinases
3 Citations (Scopus)

Selective disruption of TLR2/MyD88 interaction inhibits inflammation and attenuates Alzheimer's pathology

Rangasamy, S. B., Jana, M., Roy, A., Corbett, G. T., Kundu, M., Chandra, S., Mondal, S., Dasarathi, S., Mufson, E. J., Mishra, R. K., Luan, C-H., Bennett, D. A. & Pahan, K., Jul 10 2018, In : The Journal of clinical investigation.

Research output: Contribution to journalArticle

Pathology
Inflammation
Peptides
Alzheimer Disease
Hippocampus