Grants per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
PhD, Physical Chemistry, Sambalpur University
… → 2006
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Collaborations and top research areas from the last five years
Grants
- 14 Finished
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Development of Novel MNK Inhibitors for Treating Glioblastoma
Platanias, L. C. (PD/PI), Platanias, L. C. (PD/PI), Schiltz, G. E. (PD/PI), Schiltz, G. E. (PD/PI), Clutter, M. (Co-Investigator), Clutter, M. (Co-Investigator), Eckerdt, F. D. (Co-Investigator), Eckerdt, F. D. (Co-Investigator), Horbinski, C. M. (Co-Investigator), Horbinski, C. M. (Co-Investigator), James, C. D. (Co-Investigator), James, C. D. (Co-Investigator), Mishra, R. K. (Co-Investigator) & Mishra, R. K. (Co-Investigator)
National Institute of Neurological Disorders and Stroke
9/1/19 → 6/30/24
Project: Research project
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Identification of small molecule inhibitors of Plek2 for the treatment of myeloproliferative neoplasms
Ji, P. (PD/PI) & Mishra, R. K. (Co-Investigator)
University Hospitals Health System
1/1/19 → 3/31/21
Project: Research project
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Discovery of novel small molecule antidepressants
Schiltz, G. E. (PD/PI), Clutter, M. (Co-PD/PI) & Mishra, R. K. (Co-PD/PI)
Vanderbilt University, National Institute of Mental Health
2/1/18 → 1/31/20
Project: Research project
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Targeting EZH2 in castration-resistant prostate cancer
Schiltz, G. E. (PD/PI) & Mishra, R. K. (Co-Investigator)
U.S. Army Medical Research and Materiel Command
8/1/17 → 7/31/22
Project: Research project
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RHLCCC: Medicinal & Synthetic Chemistry Core
Mishra, R. K. (Co-Investigator), Schiltz, G. E. (Co-Investigator) & Scheidt, K. A. (Subproject PI)
8/1/16 → 7/31/18
Project: Research project
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Discovery of Potent and Selective MNK Kinase Inhibitors for the Treatment of Leukemia
Vagadia, P. P., Izquierdo-Ferrer, J., Mazewski, C., Blyth, G., Beauchamp, E. M., Clutter, M. R., Stern, C. L., Mishra, R. K., Nahotko, D., Small, S., Eckerdt, F., Platanias, L. C. & Schiltz, G. E., Mar 13 2025, In: Journal of Medicinal Chemistry. 68, 5, p. 5824-5844 21 p.Research output: Contribution to journal › Article › peer-review
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Enhancing HIV-1 latency reversal through regulating the elongating RNA Pol II pause-release by a small-molecule disruptor of PAF1C
Soliman, S. H. A., Cisneros, W. J., Iwanaszko, M., Aoi, Y., Ganesan, S., Walter, M., Zeidner, J. M., Mishra, R. K., Kim, E. Y., Wolinsky, S. M., Hultquist, J. F. & Shilatifard, A., Mar 2023, In: Science Advances. 9, 10, eadf2468.Research output: Contribution to journal › Article › peer-review
Open Access13 Scopus citations -
Prenol, but Not Vitamin C, of Fruit Binds to SARS-CoV-2 Spike S1 to Inhibit Viral Entry: Implications for COVID-19
Paidi, R. K., Jana, M., Raha, S., Mishra, R. K., Jeong, B., Sheinin, M. & Pahan, K., Jun 15 2023, In: ImmunoHorizons. 210, 12, p. 1938-1949 12 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Targeting pleckstrin-2/Akt signaling reduces proliferation in myeloproliferative neoplasm models
Han, X., Mei, Y., Mishra, R. K., Bi, H., Jain, A. D., Schiltz, G. E., Zhao, B., Sukhanova, M., Wang, P., Grigorescu, A. A., Weber, P. C., Piwinski, J. J., Prado, M. A., Paulo, J. A., Stephens, L., Anderson, K. E., Abrams, C. S., Yang, J. & Ji, P., Mar 15 2023, In: Journal of Clinical Investigation. 133, 6, e159638.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
A new robust classifier to detect hot-spots and null-spots in protein–protein interface: validation of binding pocket and identification of inhibitors in in vitro and in vivo models
Ji, Y., Tong, X., Xu, D. D., Liao, J., Davuluri, R. V., Yang, G. Y. & Mishra, R. K., Jan 1 2022, Big Data Analytics in Chemoinformatics and Bioinformatics: with Applications to Computer-Aided Drug Design, Cancer Biology, Emerging Pathogens and Computational Toxicology. Elsevier, p. 247-263 17 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
Datasets
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CCDC 998381: Experimental Crystal Structure Determination
Lee, A. (Creator), Younai, A. (Creator), Price, C. K. (Creator), Izquierdo, J. (Creator), Mishra, R. K. (Creator) & Scheidt, K. A. (Creator), Cambridge Crystallographic Data Centre, 2014
DOI: 10.5517/cc12hwv9, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/cc12hwv9&sid=DataCite
Dataset
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CCDC 1037055: Experimental Crystal Structure Determination
Wang, M. H. (Creator), Barsoum, D. (Creator), Schwamb, C. B. (Creator), Cohen, D. T. (Creator), Goess, B. C. (Creator), Riedrich, M. (Creator), Chan, A. (Creator), Maki, B. E. (Creator), Mishra, R. K. (Creator) & Scheidt, K. A. (Creator), Cambridge Crystallographic Data Centre, 2017
DOI: 10.5517/ccdc.csd.cc13t4dg, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc13t4dg&sid=DataCite
Dataset