Grants per year
Personal profile
Research Interests
A primary goal of my work is to establish the approaches and benefits of genomics informed personalized medicine. A key element of this is participation in the eMERGE consortium (http://gwas.net), where I serve as the steering committee chair. This project uses Electronic Health Records linked biobank samples (www.nugene.org) to study the genetics of disease susceptibility, therapeutic outcomes and pharmacogenomics. My group is also interested in genome informatics, particularly genome annotation and visualization technology.
Training Experience
| 1984 | Postdoctoral Fellowship, Massachusetts Institute of Technology |
Education/Academic qualification
PhD, University of Michigan
… → 1980
Keywords
- Bioinformatics
- Biotechnology
- Cell Biology
- Cytoskeleton
- Genetics
- Genomics
Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.
- 5 Similar Profiles
Dictyostelium
Medicine & Life Sciences
Electronic Health Records
Medicine & Life Sciences
Myosins
Medicine & Life Sciences
Genomics
Medicine & Life Sciences
Genome-Wide Association Study
Medicine & Life Sciences
Genome
Medicine & Life Sciences
Myosin Light Chains
Medicine & Life Sciences
Genes
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Grants 2001 2023
Genomic context alters disease manifestation of cardiomyopathies
Chisholm, R. L., George Jr, A. L., McNally, E. M., Roy-Puckelwartz, M. J. & Shah, S. J.
7/1/18 → 6/30/21
Project: Research project
Cardiomyopathies
Mutation
Hypertrophic Cardiomyopathy
Heart Failure
Dilated Cardiomyopathy
Infrastructure: Illinois Precision Medicine Consortium (IPMC)
Ackermann, R. T., Chisholm, R. L., Cristofanilli, M., Greenland, P., Kho, A. N., Ho, J., Simon, M. A., Smith, M. E. & Wehbe, F.
Office of the Director, National Institutes of Health
6/1/18 → 5/31/23
Project: Research project
Precision Medicine
Health Personnel
Organizations
Research
Biomedical Technology
CAPriCORN: Clinical Data Research Network Project: CDRN-1306-04737-IC PHASE II
Ackermann, R. T., Chisholm, R. L. & Kho, A. N.
Patient-Centered Outcomes Research Institute
9/1/17 → 3/19/19
Project: Research project
Patient Outcome Assessment
Research
Research Personnel
Health
Patient Participation
Genomic Medicine at Northwestern: Discovery and Implementation
Aufox, S. A., Chisholm, R. L., George Jr, A. L., Hayes, M. G., Kho, A. N., McNally, E. M., Rasmussen-Torvik, L. J., Roy-Puckelwartz, M. J., Smith, M. E. & Starren, J. B.
National Human Genome Research Institute
9/1/15 → 5/31/19
Project: Research project
Electronic Health Records
Medicine
National Human Genome Research Institute (U.S.)
Genome-Wide Association Study
Practice Guidelines
Subproject for Genomic Medicine at Northwestern: Discovery and Implementation
National Human Genome Research Institute
9/1/15 → 5/31/19
Project: Research project
Electronic Health Records
Medicine
National Human Genome Research Institute (U.S.)
Genome-Wide Association Study
Practice Guidelines
Research Output 1976 2018
Research Directions in the Clinical Implementation of Pharmacogenomics: An Overview of US Programs and Projects
Volpi, S., Bult, C. J., Chisholm, R. L., Deverka, P. A., Ginsburg, G. S., Jacob, H. J., Kasapi, M., McLeod, H. L., Roden, D. M., Williams, M. S., Green, E. D., Rodriguez, L. L., Aronson, S., Cavallari, L. H., Denny, J. C., Dressler, L. G., Johnson, J. A., Klein, T. E., Leeder, J. S., Piquette-Miller, M. & 12 others, May 1 2018, In : Clinical pharmacology and therapeutics. 103, 5, p. 778-786 9 p.Research output: Contribution to journal › Article
Pharmacogenetics
Research
Pharmaceutical Preparations
Precision Medicine
Drug-Related Side Effects and Adverse Reactions
The eMERGE genotype set of 83,717 subjects imputed to ~40 million variants genome wide and association with the herpes zoster medical record phenotype
The eMERGE Network, Jan 1 2018, (Accepted/In press) In : Genetic Epidemiology.Research output: Contribution to journal › Article
Electronic Health Records
Herpes Zoster
Genomics
Medical Records
Genotype
Apolipoprotein L1 Variants and Blood Pressure Traits in African Americans
Nadkarni, G. N., Galarneau, G., Ellis, S. B., Nadukuru, R., Zhang, J., Scott, S. A., Schurmann, C., Li, R., Rasmussen-Torvik, L. J., Kho, A. N., Hayes, M. G., Pacheco, J. A., Manolio, T. A., Chisholm, R. L., Roden, D. M., Denny, J. C., Kenny, E. E. & Bottinger, E. P., Mar 28 2017, In : Journal of the American College of Cardiology. 69, 12, p. 1564-1574 11 p.Research output: Contribution to journal › Article
Apolipoproteins
African Americans
Blood Pressure
Alleles
Meta-Analysis
Bedside Back to Bench: Building Bridges between Basic and Clinical Genomic Research
Manolio, T. A., Fowler, D. M., Starita, L. M., Haendel, M. A., MacArthur, D. G., Biesecker, L. G., Worthey, E., Chisholm, R. L., Green, E. D., Jacob, H. J., McLeod, H. L., Roden, D., Rodriguez, L. L., Williams, M. S., Cooper, G. M., Cox, N. J., Herman, G. E., Kingsmore, S., Lo, C., Lutz, C. & 11 others, Mar 23 2017, In : Cell. 169, 1, p. 6-12 7 p.Research output: Contribution to journal › Comment/debate
Genes
Phenotype
Inborn Genetic Diseases
Information Dissemination
Research
Expansion of the gene ontology knowledgebase and resources: The gene ontology consortium
Carbon, S., Dietze, H., Lewis, S. E., Mungall, C. J., Munoz-Torres, M. C., Basu, S., Chisholm, R. L., Dodson, R. J., Fey, P., Thomas, P. D., Mi, H., Muruganujan, A., Huang, X., Poudel, S., Hu, J. C., Aleksander, S. A., McIntosh, B. K., Renfro, D. P., Siegele, D. A., Antonazzo, G. & 31 others, Jan 1 2017, In : Nucleic acids research. 45, D1, p. D331-D338Research output: Contribution to journal › Article
Gene Ontology
Knowledge Bases
Biological Models
Systems Biology
Genes