• 1821 Citations

Research output per year

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Personal profile

Research Interests

The focus of our lab is to acquire a quantitative mechanistic characterization of synaptic players at different length scales, from a single protein to the synapse level, to describe this complexity and towards understanding of the molecular nature of information processing in the brain. We do so by developing quantitative biophysical and cell biology analyses using cutting edge single molecule and high throughput approaches that draw from cell biology, chemistry, physics and engineering.

Education/Academic qualification

PhD, University of Illinois at Urbana-Champaign

… → 2012

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Research Output

  • 1821 Citations
  • 13 Article

Mechanism of Assembly and Cooperativity of Homomeric and Heteromeric Metabotropic Glutamate Receptors

Levitz, J., Habrian, C., Bharill, S., Fu, Z., Vafabakhsh, R. & Isacoff, E. Y., Oct 5 2016, In : Neuron. 92, 1, p. 143-159 17 p.

Research output: Contribution to journalArticle

  • 54 Scopus citations

    Structural dynamics of potassium-channel gating revealed by single-molecule FRET

    Wang, S., Vafabakhsh, R., Borschel, W. F., Ha, T. & Nichols, C. G., Jan 1 2016, In : Nature Structural and Molecular Biology. 23, 1, p. 31-36 6 p.

    Research output: Contribution to journalArticle

  • 37 Scopus citations

    Conformational dynamics of a class C G-protein-coupled receptor

    Vafabakhsh, R., Levitz, J. & Isacoff, E. Y., Aug 27 2015, In : Nature. 524, 7566, p. 497-501 5 p.

    Research output: Contribution to journalArticle

  • 82 Scopus citations

    Distinct mechanisms regulating mechanical force-induced Ca2+ signals at the plasma membrane and the ER in human MSCs

    Kim, T. J., Joo, C., Seong, J., Vafabakhsh, R., Botvinick, E. L., Berns, M. W., Palmer, A. E., Wang, N., Ha, T., Jakobsson, E., Sun, J. & Wang, Y., Feb 10 2015, In : eLife. 2015, 4, e04876.

    Research output: Contribution to journalArticle

  • 30 Scopus citations

    Designing a nine cysteine-less DNA packaging motor from bacteriophage T4 reveals new insights into ATPase structure and function

    Kondabagil, K., Dai, L., Vafabakhsh, R., Ha, T., Draper, B. & Rao, V. B., Nov 1 2014, In : Virology. 468, p. 660-668 9 p.

    Research output: Contribution to journalArticle

  • 3 Scopus citations