Grants per year
Personal profile
Research Interests
The focus of our lab is to acquire a quantitative mechanistic characterization of synaptic players at different length scales, from a single protein to the synapse level, to describe this complexity and towards understanding of the molecular nature of information processing in the brain. We do so by developing quantitative biophysical and cell biology analyses using cutting edge single molecule and high throughput approaches that draw from cell biology, chemistry, physics and engineering.
Education/Academic qualification
PhD, University of Illinois at Urbana-Champaign
… → 2012
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Network
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Optogenomic mapping of chromatin accessibility in live cells
Wang, X., Vafabakhsh, R. & Wang, J.
National Institute of General Medical Sciences
9/24/22 → 7/31/26
Project: Research project
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Kinetic Imaging Plate Reader for Drug Discovery and Biology
George, A. L., Arispe, L., Bass, J., Burridge, P., DeCaen, P. G., Gianneschi, N., Horvath, C. M., Kiskinis, E., Klein, W. L., Miller, R. J., Morimoto, R. I., Moskal, J. R., Penzes, P., Prakriya, M., Scheidt, K. A., Surmeier Jr, D. J. & Vafabakhsh, R.
Office of the Director, National Institutes of Health
9/1/21 → 8/31/23
Project: Research project
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Quantitative analysis of metabotropic glutamate receptor activation and modulation
National Institute of General Medical Sciences
9/15/20 → 8/31/25
Project: Research project
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C-093: Visualizing the dynamic process of activation and modulation of adhesion GPCRs
Searle Funds at The Chicago Community Trust
1/1/17 → 12/31/21
Project: Research project
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An integrative approach to molecular dynamics and single molecule FRET techniques
Moradi, M., Lu, M., Vafabakhsh, R. & Heyes, C. D., Feb 10 2023, In: Biophysical Journal. 122, 3S1, p. 36a-37aResearch output: Contribution to journal › Article › peer-review
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Mapping the KRAS proteoform landscape in colorectal cancer identifies truncated KRAS4B that decreases MAPK signaling
Adams, L. M., DeHart, C. J., Drown, B. S., Anderson, L. C., Bocik, W., Boja, E. S., Hiltke, T. M., Hendrickson, C. L., Rodriguez, H., Caldwell, M., Vafabakhsh, R. & Kelleher, N. L., Jan 2023, In: Journal of Biological Chemistry. 299, 1, 102768.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Conformational fingerprinting of allosteric modulators in metabotropic glutamate receptor 2
Wey-Hung Liauw, B., Foroutan, A., Schamber, M., Lu, W., Afsari, H. S. & Vafabakhsh, R., Jul 2022, In: eLife. 11, e78982.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
DNAcycP: a deep learning tool for DNA cyclizability prediction
Li, K., Carroll, M., Vafabakhsh, R., Wang, X. A. & Wang, J. P., Apr 8 2022, In: Nucleic acids research. 50, 6, p. 3142-3154 13 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Mechanism of sensitivity modulation in the calcium-sensing receptor via electrostatic tuning
Schamber, M. R. & Vafabakhsh, R., Dec 2022, In: Nature communications. 13, 1, 2194.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations