Grants per year
Personal profile
Research Interests
The focus of our lab is to acquire a quantitative mechanistic characterization of synaptic players at different length scales, from a single protein to the synapse level, to describe this complexity and towards understanding of the molecular nature of information processing in the brain. We do so by developing quantitative biophysical and cell biology analyses using cutting edge single molecule and high throughput approaches that draw from cell biology, chemistry, physics and engineering.
Education/Academic qualification
PhD, University of Illinois at Urbana-Champaign
… → 2012
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Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Kinetic Imaging Plate Reader for Drug Discovery and Biology
George, A. L., Arispe, L., Bass, J., Burridge, P., DeCaen, P. G., Gianneschi, N., Horvath, C. M., Kiskinis, E., Klein, W. L., Miller, R. J., Morimoto, R. I., Moskal, J. R., Penzes, P., Prakriya, M., Scheidt, K. A., Surmeier Jr, D. J. & Vafabakhsh, R.
Office of the Director, National Institutes of Health
9/1/21 → 8/31/22
Project: Research project
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Quantitative analysis of metabotropic glutamate receptor activation and modulation
National Institute of General Medical Sciences
9/15/20 → 8/31/25
Project: Research project
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C-093: Visualizing the dynamic process of activation and modulation of adhesion GPCRs
Searle Funds at The Chicago Community Trust
1/1/17 → 12/31/21
Project: Research project
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DNAcycP: a deep learning tool for DNA cyclizability prediction
Li, K., Carroll, M., Vafabakhsh, R., Wang, X. A. & Wang, J. P., Apr 8 2022, In: Nucleic acids research. 50, 6, p. 3142-3154 13 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Mechanism of sensitivity modulation in the calcium-sensing receptor via electrostatic tuning
Schamber, M. R. & Vafabakhsh, R., Dec 2022, In: Nature communications. 13, 1, 2194.Research output: Contribution to journal › Article › peer-review
Open Access -
A viral genome packaging ring-ATPase is a flexibly coordinated pentamer
Dai, L., Singh, D., Lu, S., Kottadiel, V. I., Vafabakhsh, R., Mahalingam, M., Chemla, Y. R., Ha, T. & Rao, V. B., Dec 2021, In: Nature communications. 12, 1, 6548.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Conformational rearrangement during activation of a metabotropic glutamate receptor
Liauw, B. W. H., Afsari, H. S. & Vafabakhsh, R., Mar 2021, In: Nature Chemical Biology. 17, 3, p. 291-297 7 p.Research output: Contribution to journal › Article › peer-review
12 Scopus citations -
FRET-based dynamic structural biology: Challenges, perspectives and an appeal for open-science practices
Lerner, E., Barth, A., Hendrix, J., Ambrose, B., Birkedal, V., Blanchard, S. C., Börner, R., Chung, H. S., Cordes, T., Craggs, T. D., Deniz, A. A., Diao, J., Fei, J., Gonzalez, R. L., Gopich, I. V., Ha, T., Hanke, C. A., Haran, G., Hatzakis, N. S., Hohng, S. & 27 others, , Mar 2021, In: eLife. 10, e60416.Research output: Contribution to journal › Review article › peer-review
Open Access34 Scopus citations