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Personal profile

Education/Academic qualification

Organic Chemistry, PhD, Harvard University

… → 1974

Chemistry, BS, Pennsylvania State University

… → 1968

Fingerprint Dive into the research topics where Richard B Silverman is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

Nitric Oxide Synthase Type I Medicine & Life Sciences
Aminobutyrates Medicine & Life Sciences
Monoamine Oxidase Medicine & Life Sciences
Transaminases Medicine & Life Sciences
4-Aminobutyrate Transaminase Medicine & Life Sciences
Enzymes Medicine & Life Sciences
Nitric Oxide Synthase Medicine & Life Sciences
gamma-Aminobutyric Acid Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Grants 2002 2024

Amyotrophic Lateral Sclerosis
Motor Neurons
Neurodegenerative Diseases
Motor Neuron Disease
Drug Discovery
Motor Neuron Disease
Amyotrophic Lateral Sclerosis
Drug Discovery
Neurodegenerative Diseases
Health
Nitric Oxide Synthase Type I
Nitric Oxide Synthase
Melanoma
Cerebral Palsy
Hydrogen Peroxide
training program
chemistry
transdisciplinary
life sciences
expertise

Research Output 1968 2019

Glucosylceramidase
Parkinson Disease
Phenotype
Mutation
Dopaminergic Neurons

Conversion of Quinazoline Modulators from Inhibitors to Activators of β-Glucocerebrosidase

Zheng, J., Jeon, S., Jiang, W., Burbulla, L., Ysselstein, D., Oevel, K., Krainc, D. & Silverman, R. B., Feb 14 2019, In : Journal of Medicinal Chemistry. 62, 3, p. 1218-1230 13 p.

Research output: Contribution to journalArticle

Glucosylceramidase
Quinazolines
Parkinson Disease
Mutant Proteins
Structure-Activity Relationship
Aminoquinolines
Nitric Oxide Synthase Type I
Nitriles
Pharmaceutical Chemistry
Bistris
Fluorobenzenes
Nitric Oxide Synthase Type I
Pharmaceutical Chemistry
Permeability
alpha-aminopyridine