Grants per year
Personal profile
Research Interests
My research interests revolve around understanding the risk factors, including host genetic risk, and improving outcomes of critically ill patients with serious infections. This includes severe community-acquired pneumonia, sepsis of all causes, and nosocomial infections, particularly ventilator-associated pneumonia.
Certifications and Licenses
| Internal Medicine | |
| Critical Care Medicine | |
| Pulmonary Disease |
Training Experience
| 1983 | Residency, Butterworth Hospital |
| 1985 | Fellowship, Henry Ford Hospital |
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Medicine, MD, Indiana University
… → 1980
Research interests keywords
- Critical Care
- Critical Care Outcomes
- Genetics: Medical
- Pneumonia
Fingerprint
Dive into the research topics where Richard G Wunderink is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Prot #BTI-203: A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Adjunctive Recombinant Human Plasma Gelsolin With Standard of Care for Moderate-to-Severe ARDS Due to Pneumonia or Other Infections
Wunderink, R. G. (PD/PI)
Ergomed Clinical Research Inc., BioAegis Therapeutics, Inc.
9/8/24 → 9/8/27
Project: Research project
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Machine learning to predict the development of ventilator-associated pneumonia
Luo, Y. (PD/PI), Wunderink, R. G. (PD/PI), Gao, C. A. (Other) & Singer, B. (Other)
American Thoracic Society, Inc.
7/1/24 → 7/1/25
Project: Research project
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Machine learning to predict cure in severe pneumonia episodes
Gao, C. A. (PD/PI), Andrei, A. (Other), Budinger, G. S. (Other), Luo, Y. (Other), Misharin, A. (Other), Singer, B. (Other), Starren, J. (Other), Walunas, T. L. (Other) & Wunderink, R. G. (Other)
National Heart, Lung, and Blood Institute
4/1/24 → 3/31/29
Project: Research project
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The Neu-Lung Consortium: Neutrophilic Mechanisms of Inflammation, Injury, and Repair in Lung and Airways Diseases
Fourati, S. (Co-Investigator), Luo, Y. (Co-Investigator), Morales-Nebreda, L. (Co-Investigator), Scholtens, D. M. (Co-Investigator), Wunderink, R. G. (Co-Investigator) & Walunas, T. L. (Other)
National Institute of Allergy and Infectious Diseases
4/1/24 → 3/31/29
Project: Research project
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Prot #STU00204868-MOD0146: Validation of a Host-Protein Based Assay to Distinguish Between Viral and Bacterial Infection in Critically Ill Patients with CommunityAcquired Pneumonia: A Cohort Study
Pickens, C. I. (PD/PI) & Wunderink, R. G. (Co-Investigator)
3/18/24 → 3/18/27
Project: Research project
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An Observational Cohort Study of Bronchoalveolar Lavage Fluid Galactomannan and Aspergillus Culture Positivity in Patients Requiring Mechanical Ventilation
Gao, C. A., Markov, N. S., Pickens, C., Pawlowski, A., Kang, M., Walter, J. M., Singer, B. D. & Wunderink, R. G., Mar 1 2025, In: Open Forum Infectious Diseases. 12, 3, ofaf090.Research output: Contribution to journal › Article › peer-review
Open Access -
Antibiotic de-escalation patterns and outcomes in critically ill patients with suspected pneumonia as informed by bronchoalveolar lavage results
The N. U. SCRIPT Study Investigators, 2025, (Accepted/In press) In: European Journal of Clinical Microbiology and Infectious Diseases.Research output: Contribution to journal › Article › peer-review
Open Access -
Impact of healthcare system strain on the implementation of ICU sedation practices and encephalopathy burden during the early COVID-19 pandemic
Clark, J. R., Batra, A., Tessier, R. A., Greathouse, K., Dickson, D., Ammar, A., Hamm, B., Rosenthal, L. J., Lombardo, T., Koralnik, I. J., Skolarus, L. E., Schroedl, C. J., Budinger, G. R. S., Wunderink, R. G., Dematte, J. E., Ungvari, Z. & Liotta, E. M., Feb 2025, In: GeroScience. 47, 1, p. 189-203 15 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Streptococcus pneumoniae Serotype Distribution Among US Adults Hospitalized With Community-Acquired Pneumonia, 2019–2020
Ramirez, J. A., Hubler, R. A., Ali, M., Gray, S. L., Carrico, R., McNaughton, C. D., Wunderink, R. G., Dela Cruz, C. S., Chilson, E. L., Cané, A. D., Isturiz, R. E., Pride, M. W., Jodar, L., Gessner, B. D. & Grant, L. R., Jan 1 2025, In: Open Forum Infectious Diseases. 12, 1, ofae727.Research output: Contribution to journal › Article › peer-review
Open Access -
Antibiotic use during influenza infection augments lung eosinophils that impair immunity against secondary bacterial pneumonia
Zuttion, M. S. S. R., Parimon, T., Bora, S. A., Yao, C., Lagree, K., Gao, C. A., Wunderink, R. G., Kitsios, G. D., Morris, A., Zhang, Y., McVerry, B. J., Modes, M. E., Marchevsky, A. M., Stripp, B. R., Soto, C. M., Wang, Y., Merene, K., Cho, S., Victor, B. L. & Vujkovic-Cvijin, I. & 6 others, , Nov 1 2024, In: Journal of Clinical Investigation. 134, 21, e180986.Research output: Contribution to journal › Article › peer-review
Open Access
Datasets
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Angiotensin I and angiotensin II concentrations and their ratio in catecholamine-resistant vasodilatory shock
Bellomo, R. (Creator), Wunderink, R. G. (Creator), Szerlip, H. (Creator), English, S. W. (Creator), Busse, L. W. (Creator), Deane, A. M. (Creator), Khanna, A. K. (Creator), McCurdy, M. T. (Creator), Ostermann, M. (Creator), Young, P. J. (Creator), Handisides, D. R. (Creator), Chawla, L. S. (Creator), Tidmarsh, G. F. (Creator) & Albertson, T. E. (Creator), figshare, 2020
DOI: 10.6084/m9.figshare.c.4847352, https://springernature.figshare.com/collections/Angiotensin_I_and_angiotensin_II_concentrations_and_their_ratio_in_catecholamine-resistant_vasodilatory_shock/4847352
Dataset
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Ceftolozane/tazobactam versus meropenem in patients with ventilated hospital-acquired bacterial pneumonia: subset analysis of the ASPECT-NP randomized, controlled phase 3 trial
Timsit, J.-F. (Creator), Huntington, J. A. (Creator), Wunderink, R. G. (Creator), Shime, N. (Creator), Kollef, M. H. (Creator), Kivistik, Ü. (Creator), Nováček, M. (Creator), Réa-Neto, Á. (Creator), Martin-Loeches, I. (Creator), Yu, B. (Creator), Jensen, E. H. (Creator), Butterton, J. R. (Creator), Wolf, D. J. (Creator), Rhee, E. G. (Creator) & Bruno, C. J. (Creator), figshare, 2021
DOI: 10.6084/m9.figshare.c.5556746, https://springernature.figshare.com/collections/Ceftolozane_tazobactam_versus_meropenem_in_patients_with_ventilated_hospital-acquired_bacterial_pneumonia_subset_analysis_of_the_ASPECT-NP_randomized_controlled_phase_3_trial/5556746
Dataset
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Outcomes in participants with ventilated nosocomial pneumonia and organ failure treated with ceftolozane/tazobactam versus meropenem: a subset analysis of the phase 3, randomized, controlled ASPECT-NP trial
Martin-Loeches, I. (Creator), Shorr, A. F. (Creator), Wunderink, R. G. (Creator), Kollef, M. H. (Creator), Timsit, J.-F. (Creator), Yu, B. (Creator), Huntington, J. A. (Creator), Jensen, E. (Creator) & Bruno, C. J. (Creator), figshare, 2023
DOI: 10.6084/m9.figshare.c.6583244, https://springernature.figshare.com/collections/Outcomes_in_participants_with_ventilated_nosocomial_pneumonia_and_organ_failure_treated_with_ceftolozane_tazobactam_versus_meropenem_a_subset_analysis_of_the_phase_3_randomized_controlled_ASPECT-NP_trial/6583244
Dataset
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CarpeDiem datasets
Gao, C. A. (Creator), Markov, N. S. (Creator), Budinger, G. S. (Creator), Wunderink, R. G. (Creator), Singer, B. D. (Creator), Misharin, A. V. (Creator) & Investigators, N. S. (Creator), ZENODO, May 10 2022
DOI: 10.5281/zenodo.6528915, https://zenodo.org/records/6528915
Dataset
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Initiating angiotensin II at lower vasopressor doses in vasodilatory shock: an exploratory post-hoc analysis of the ATHOS-3 clinical trial
Wieruszewski, P. M. (Creator), Bellomo, R. (Creator), Busse, L. W. (Creator), Ham, K. R. (Creator), Zarbock, A. (Creator), Khanna, A. K. (Creator), Deane, A. M. (Creator), Ostermann, M. (Creator), Wunderink, R. G. (Creator), Boldt, D. W. (Creator), Kroll, S. (Creator), Greenfeld, C. R. (Creator), Hodges, T. (Creator) & Chow, J. H. (Creator), figshare, 2023
DOI: 10.6084/m9.figshare.c.6634033, https://springernature.figshare.com/collections/Initiating_angiotensin_II_at_lower_vasopressor_doses_in_vasodilatory_shock_an_exploratory_post-hoc_analysis_of_the_ATHOS-3_clinical_trial/6634033
Dataset