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Personal profile

Education/Academic qualification

PhD, The University of Chicago

… → 1978

Fingerprint Dive into the research topics where Richard I Morimoto is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

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Shock Medicine & Life Sciences
Hot Temperature Medicine & Life Sciences
Heat-Shock Response Medicine & Life Sciences
Proteins Medicine & Life Sciences
Heat-Shock Proteins Medicine & Life Sciences
Molecular Chaperones Medicine & Life Sciences
Caenorhabditis elegans Medicine & Life Sciences
Genes Medicine & Life Sciences

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Grants 1998 2023

Homeostasis
Proteome
Proteins
Protein Conformation
Protein Folding
Alzheimer Disease
Neurons
Health
Genetic Testing
Communication
Neurons
Genes
Neurodegenerative Diseases
Molecular Chaperones
Proteasome Endopeptidase Complex
Alzheimer Disease
Proteins
Neurodegenerative Diseases
Molecular Chaperones
Proteasome Endopeptidase Complex
Alzheimer Disease
Proteins

Research Output 1975 2019

Deconvoluting Stress-Responsive Proteostasis Signaling Pathways for Pharmacologic Activation Using Targeted RNA Sequencing

Grandjean, J. M. D., Plate, L., Morimoto, R. I., Bollong, M. J., Powers, E. T. & Luke Wiseman, R., Apr 19 2019, In : ACS chemical biology. 14, 4, p. 784-795 12 p.

Research output: Contribution to journalArticle

RNA Sequence Analysis
Heat-Shock Response
Assays
Oxidative Stress
Chemical activation

Erratum: Metformin Targets Mitochondrial Electron Transport to Reduce Air-Pollution-Induced Thrombosis (Cell Metabolism (2019) 29(2) (335–347.e5), (S1550413118305862) (10.1016/j.cmet.2018.09.019))

Soberanes, S., Misharin, A. V., Jairaman, A., Morales-Nebreda, L., McQuattie-Pimentel, A. C., Cho, T., Hamanaka, R. B., Meliton, A. Y., Reyfman, P. A., Walter, J. M., Chen, C. I., Chi, M., Chiu, S., Gonzalez-Gonzalez, F. J., Antalek, M., Abdala-Valencia, H., Chiarella, S. E., Sun, K. A., Woods, P. S., Ghio, A. J. & 12 others, Jain, M., Perlman, H., Ridge, K. M., Morimoto, R. I., Sznajder, J. I., Balch, W. E., Bhorade, S. M., Bharat, A., Prakriya, M., Chandel, N. S., Mutlu, G. M. & Budinger, G. R. S., Feb 5 2019, In : Cell Metabolism. 29, 2, 1 p.

Research output: Contribution to journalComment/debate

Metformin
Air Pollution
Electron Transport
Names
Publications
1 Citation (Scopus)

Tau protein aggregates inhibit the protein-folding and vesicular trafficking arms of the cellular proteostasis network

Yu, A., Fox, S. G., Cavallini, A., Kerridge, C., O'Neill, M. J., Wolak, J., Bose, S. & Morimoto, R. I., Jan 1 2019, In : Journal of Biological Chemistry. 294, 19, p. 7917-7930 14 p.

Research output: Contribution to journalArticle

Protein folding
tau Proteins
Molecular Chaperones
Protein Folding
Agglomeration
19 Citations (Scopus)

Large-scale investigation of the reasons why potentially important genes are ignored

Stoeger, T., Gerlach, M., Morimoto, R. I. & Nunes Amaral, L. A., Sep 2018, In : PLoS biology. 16, 9, e2006643.

Research output: Contribution to journalArticle

Genes
genes
National Institutes of Health
Knowledge Bases
biomedical research
2 Citations (Scopus)

Metformin Targets Mitochondrial Electron Transport to Reduce Air-Pollution-Induced Thrombosis

Soberanes, S., Misharin, A. V., Jairaman, A., Morales-Nebreda, L., McQuattie-Pimentel, A. C., Cho, T., Hamanaka, R. B., Meliton, A. Y., Reyfman, P. A., Walter, J. M., Chen, C-I., Chi, M., Chiu, S., Gonzalez-Gonzalez, F. J., Antalek, M., Abdala-Valencia, H., Chiarella, S. E., Sun, K. A., Woods, P. S., Ghio, A. J. & 12 others, Jain, M., Perlman, H., Ridge, K. M., Morimoto, R. I., Sznajder, J. I., Balch, W. E., Bhorade, S. M., Bharat, A., Prakriya, M., Chandel, N. S., Mutlu, G. M. & Budinger, G. R. S., Oct 11 2018, In : Cell Metabolism.

Research output: Contribution to journalArticle

Metformin
Air Pollution
Electron Transport
Particulate Matter
Alveolar Macrophages