Grants per year
Personal profile
Research Interests
Our laboratory is interested in the role of receptors in the regulation of nerve cell function.We are particularly interested in the role of cytokines in nerve cell biology.The effects of cytokines on neural stem cell development and in the genesis of chronic pain syndromes are of current interest.We study these phenomena using biochemistry,molecular biology,electrophysiology,mouse genetics and imaging.Projects in our laboratory involve the development of drugs that act on cytokine receptors as well as the molecular basis for pain in osteoarthritis and diabetic neuropathy.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
PhD, University of Cambridge
… → 1976
Research interests
- Cytokines
- Drug Discovery
- Electrophysiology
- Neuroscience
- Pain
- Pharmacology
- Physiology
- Stem Cells
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Kinetic Imaging Plate Reader for Drug Discovery and Biology
George, A. L., Arispe, L., Bass, J., Burridge, P., DeCaen, P. G., Gianneschi, N., Horvath, C. M., Kiskinis, E., Klein, W. L., Miller, R. J., Morimoto, R. I., Moskal, J. R., Penzes, P., Prakriya, M., Scheidt, K. A., Surmeier Jr, D. J. & Vafabakhsh, R.
Office of the Director, National Institutes of Health
9/1/21 → 8/31/23
Project: Research project
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Neuron-Keratinocyte Communication in the Epidermis in Normal and Diabetic Wound Healing
National Institute of Arthritis and Musculoskeletal and Skin Diseases
9/11/20 → 6/30/24
Project: Research project
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Effects of Small Molecule Ligands on ACKR3 ReceptorsS
Hopkins, B. E., Masuho, I., Ren, D., Iyamu, I. D., Lv, W., Malik, N., Martemyanov, K. A., Schiltz, G. E. & Miller, R. J., Sep 2022, In: Molecular pharmacology. 102, 3, p. 128-138 11 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Mitochondrial calcium uniporter deletion prevents painful diabetic neuropathy by restoring mitochondrial morphology and dynamics
George, D. S., Hackelberg, S., Jayaraj, N. D., Ren, D., Edassery, S. L., Rathwell, C. A., Miller, R. E., Malfait, A. M., Savas, J. N., Miller, R. J. & Menichella, D. M., Mar 1 2022, In: Pain. 163, 3, p. 560-578 19 p.Research output: Contribution to journal › Article › peer-review
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An autophagy-related protein Becn2 regulates cocaine reward behaviors in the dopaminergic system
Kim, Y. J., Kong, Q., Yamamoto, S., Kuramoto, K., Huang, M., Wang, N., Hwa, J., Xiao, T., Levine, B., Qiu, X., Zhao, Y., Miller, R. J., Dong, H., Meltzer, H. Y., Xu, M. & He, C., Feb 19 2021, In: Science Advances. 7, 8, eabc8310.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Basic Mechanisms of Pain in Osteoarthritis: Experimental Observations and New Perspectives
Malfait, A. M., Miller, R. E. & Miller, R. J., May 2021, In: Rheumatic Disease Clinics of North America. 47, 2, p. 165-180 16 p.Research output: Contribution to journal › Review article › peer-review
4 Scopus citations -
Cutaneous innervation in impaired diabetic wound healing
Nowak, N. C., Menichella, D. M., Miller, R. & Paller, A. S., Oct 2021, In: Translational Research. 236, p. 87-108 22 p.Research output: Contribution to journal › Review article › peer-review
7 Scopus citations