Grants per year
Personal profile
Research Interests
Our laboratory is interested in the role of receptors in the regulation of nerve cell function.We are particularly interested in the role of cytokines in nerve cell biology.The effects of cytokines on neural stem cell development and in the genesis of chronic pain syndromes are of current interest.We study these phenomena using biochemistry,molecular biology,electrophysiology,mouse genetics and imaging.Projects in our laboratory involve the development of drugs that act on cytokine receptors as well as the molecular basis for pain in osteoarthritis and diabetic neuropathy.
Education/Academic qualification
PhD, University of Cambridge
… → 1976
Research interests
- Cytokines
- Drug Discovery
- Electrophysiology
- Neuroscience
- Pain
- Pharmacology
- Physiology
- Stem Cells
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Grants
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Neuron-Keratinocyte Communication in the Epidermis in Normal and Diabetic Wound Healing
National Institute of Arthritis and Musculoskeletal and Skin Diseases
9/11/20 → 8/31/24
Project: Research project
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Pelvic Pain and Depression
Flury, S. C., Griffith, J. W., Klumpp, D., Parrish, T. B., Schaeffer, A. J. & Miller, R. J.
National Institute of Diabetes and Digestive and Kidney Diseases
7/1/19 → 8/13/22
Project: Research project
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Osteoarthritis Progression And Sensory Pathway Alterations
Rush University Medical Center, National Institute of Arthritis and Musculoskeletal and Skin Diseases
5/14/19 → 3/31/24
Project: Research project
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The molecular basis of Interleukin-31 driven itch
McNeil, B. D., Zhang, L. & Miller, R. J.
National Institute of Arthritis and Musculoskeletal and Skin Diseases
4/1/19 → 2/29/24
Project: Research project
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Project 4: AWATRAMANI
Awatramani, R. & Miller, R. J.
National Institute on Drug Abuse
9/1/18 → 6/30/23
Project: Research project
Research Output
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Microarray analyses of the dorsal root ganglia support a role for innate neuro-immune pathways in persistent pain in experimental osteoarthritis
Miller, R. E., Tran, P. B., Ishihara, S., Syx, D., Ren, D., Miller, R. J., Valdes, A. M. & Malfait, A. M., May 2020, In: Osteoarthritis and Cartilage. 28, 5, p. 581-592 12 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
Orai1 Channels Are Essential for Amplification of Glutamate-Evoked Ca2+ Signals in Dendritic Spines to Regulate Working and Associative Memory
Maneshi, M. M., Toth, A. B., Ishii, T., Hori, K., Tsujikawa, S., Shum, A. K., Shrestha, N., Yamashita, M., Miller, R. J., Radulovic, J., Swanson, G. T. & Prakriya, M., Dec 1 2020, In: Cell reports. 33, 9, 108464.Research output: Contribution to journal › Article › peer-review
Open Access -
Pain-related behaviors and abnormal cutaneous innervation in a murine model of classical Ehlers-Danlos syndrome
Syx, D., Miller, R. E., Obeidat, A. M., Tran, P. B., Vroman, R., Malfait, Z., Miller, R. J., Malfait, F. & Malfait, A. M., Oct 1 2020, In: Pain. 161, 10, p. 2274-2283 10 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
The innate immune response as a mediator of osteoarthritis pain
Miller, R. J., Malfait, A. M. & Miller, R. E., May 2020, In: Osteoarthritis and Cartilage. 28, 5, p. 562-571 10 p.Research output: Contribution to journal › Review article › peer-review
6 Scopus citations -
The nociceptive innervation of the normal and osteoarthritic mouse knee
Obeidat, A. M., Miller, R. E., Miller, R. J. & Malfait, A. M., Nov 2019, In: Osteoarthritis and Cartilage. 27, 11, p. 1669-1679 11 p.Research output: Contribution to journal › Article › peer-review
7 Scopus citations