Grants per year
Personal profile
Research Interests
Our laboratory is interested in the role of receptors in the regulation of nerve cell function.We are particularly interested in the role of cytokines in nerve cell biology.The effects of cytokines on neural stem cell development and in the genesis of chronic pain syndromes are of current interest.We study these phenomena using biochemistry,molecular biology,electrophysiology,mouse genetics and imaging.Projects in our laboratory involve the development of drugs that act on cytokine receptors as well as the molecular basis for pain in osteoarthritis and diabetic neuropathy.
Education/Academic qualification
PhD, University of Cambridge
… → 1976
Research interests
- Cytokines
- Drug Discovery
- Electrophysiology
- Neuroscience
- Pain
- Pharmacology
- Physiology
- Stem Cells
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Grants
Pelvic Pain and Depression
Flury, S. C., Griffith, J. W., Klumpp, D., Miller, R. J., Parrish, T. B. & Schaeffer, A. J.
National Institute of Diabetes, Digestive and Kidney Diseases
7/1/19 → 8/13/22
Project: Research project
Osteoarthritis Progression And Sensory Pathway Alterations
Rush University, National Institute of Arthritis and Musculoskeletal and Skin Diseases
5/14/19 → 3/31/24
Project: Research project
The molecular basis of Interleukin-31 driven itch
McNeil, B. D., Miller, R. J. & Zhang, L.
National Institute of Arthritis and Musculoskeletal and Skin Diseases
4/1/19 → 2/29/24
Project: Research project
Center for chronic pain and drug abuse
Apkarian, A., Awatramani, R., Drenan, R. M., Graves, S. M., Griffith, J. W., Huang, L., Jovasevic, V., Martina, M., Miller, R. J., Parrish, T. B., Procissi, D., Radulovic, J., Rodes, M. E., Schnitzer, T. J. & Surmeier Jr, D. J.
National Institute on Drug Abuse
9/1/18 → 6/30/23
Project: Research project
Targeting chemokine signaling and MAPK/ERK pathway in advanced prostate cancer
Yu, J., Cristofanilli, M., Hussain, M., Miller, R. J., Schiltz, G. E., Yang, X. J., Zhang, B. & Zhao, C.
12/31/17 → 12/31/20
Project: Research project
Research Output
The innate immune response as a mediator of osteoarthritis pain
Miller, R. J., Malfait, A. M. & Miller, R. E., May 2020, In : Osteoarthritis and Cartilage. 28, 5, p. 562-571 10 p.Research output: Contribution to journal › Review article
2
Scopus
citations
The nociceptive innervation of the normal and osteoarthritic mouse knee
Obeidat, A. M., Miller, R. E., Miller, R. J. & Malfait, A. M., Jan 1 2019, (Accepted/In press) In : Osteoarthritis and Cartilage.Research output: Contribution to journal › Article
2
Scopus
citations
An aggrecan fragment drives osteoarthritis pain through Toll-like receptor 2
Miller, R. E., Ishihara, S., Tran, P. B., Golub, S. B., Last, K., Miller, R. J., Fosang, A. J. & Malfait, A. M., Mar 22 2018, In : JCI Insight. 3, 6Research output: Contribution to journal › Article
Open Access
15
Scopus
citations
Reducing CXCR4-mediated nociceptor hyperexcitability reverses painful diabetic neuropathy
Jayaraj, N. D., Bhattacharyya, B. J., Belmadani, A. A., Ren, D., Rathwell, C. A., Hackelberg, S., Hopkins, B. E., Gupta, H. R., Miller, R. J. & Menichella, D. M., Jun 1 2018, In : Journal of Clinical Investigation. 128, 6, p. 2205-2225 21 p.Research output: Contribution to journal › Article
11
Scopus
citations
TRPV1 and the MCP-1/CCR2 Axis Modulate Post-UTI Chronic Pain
Rosen, J. M., Yaggie, R. E., Woida, P. J., Miller, R. J., Schaeffer, A. J. & Klumpp, D., Dec 1 2018, In : Scientific Reports. 8, 1, 7188.Research output: Contribution to journal › Article
1
Scopus
citations