• 10581 Citations
1986 …2020

Research output per year

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Research Output

2020

Differential Inhibition of APOBEC3 DNA-Mutator Isozymes by Fluoro- and Non-Fluoro-Substituted 2′-Deoxyzebularine Embedded in Single-Stranded DNA

Kvach, M. V., Barzak, F. M., Harjes, S., Schares, H. A. M., Kurup, H. M., Jones, K. F., Sutton, L., Donahue, J., D'Aquila, R. T., Jameson, G. B., Harki, D. A., Krause, K. L., Harjes, E. & Filichev, V. V., Apr 1 2020, In : ChemBioChem. 21, 7, p. 1028-1035 8 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Transgender Women’s Concerns and Preferences on Potential Future Long-Acting Biomedical HIV Prevention Strategies: The Case of Injections and Implanted Medication Delivery Devices (IMDDs)

Rael, C. T., Martinez, M., Giguere, R., Bockting, W., MacCrate, C., Mellman, W., Valente, P., Greene, G. J., Sherman, S. G., Footer, K. H. A., D’Aquila, R. T., Carballo-Diéguez, A. & Hope, T. J., May 1 2020, In : AIDS and behavior. 24, 5, p. 1452-1462 11 p.

Research output: Contribution to journalArticle

1 Scopus citations
2019

Exploring new and existing PrEP modalities among female sex workers and women who inject drugs in a U.S. city

Footer, K. H. A., Lim, S., Rael, C. T., Greene, G. J., Carballa-Diéguez, A., Giguere, R., Martinez, M., Bockting, W., D’Aquila, R. & Sherman, S. G., Oct 3 2019, In : AIDS Care - Psychological and Socio-Medical Aspects of AIDS/HIV. 31, 10, p. 1207-1213 7 p.

Research output: Contribution to journalArticle

5 Scopus citations

Harvard HIV and aging workshop: Perspectives and Priorities from Claude D. Pepper Centers and Centers for AIDS Research

Montano, M., Bhasin, S., D'Aquila, R. T., Erlandson, K. M., Evans, W. J., Funderburg, N. T., Justice, A., Ndhlovu, L. C., Ojikutu, B., Pahor, M., Pahwa, S., Ryan, A. S., Schrack, J., Schultz, M. B., Sebastiani, P., Sinclair, D. A., Tripp, J., Walker, B., Womack, J. A., Yung, R. & 1 others, Reeves, R. K., Nov 1 2019, In : AIDS research and human retroviruses. 35, 11-12, p. 999-1012 14 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
17 Scopus citations

Knowledge About Oral PrEP Among Transgender Women in New York City

Rael, C. T., Martinez, M., Giguere, R., Bockting, W., MacCrate, C., Mellman, W., Valente, P., Greene, G. J., Sherman, S. G., Footer, K. H. A., D’Aquila, R., Carballo-Diéguez, A. & Hope, T. J., Oct 1 2019, In : AIDS and behavior. 23, 10, p. 2779-2783 5 p.

Research output: Contribution to journalArticle

Systemic inflammation is elevated among both HIV-uninfected and HIV-infected young MSM

Morgan, E., Taylor, H. E., Ryan, D. T., D'Aquila, R. T. & Mustanski, B., Mar 15 2019, In : AIDS (London, England). 33, 4, p. 757-759 3 p.

Research output: Contribution to journalArticle

2 Scopus citations
2018

Barriers and Facilitators to Oral PrEP Use Among Transgender Women in New York City

Rael, C. T., Martinez, M., Giguere, R., Bockting, W., MacCrate, C., Mellman, W., Valente, P., Greene, G. J., Sherman, S., Footer, K. H. A., D’Aquila, R. T. & Carballo-Diéguez, A., Nov 1 2018, In : AIDS and behavior. 22, 11, p. 3627-3636 10 p.

Research output: Contribution to journalArticle

17 Scopus citations
7 Scopus citations

Learning about "known Unknowns" and "unknown Unknowns" to cure HIV

D'Aquila, R., Nov 20 2018, In : Annals of internal medicine. 169, 10, p. 719-720 2 p.

Research output: Contribution to journalEditorial

mTOR signaling mediates effects of common gamma-chain cytokines on T cell proliferation and exhaustion: implications for HIV-1 persistence and cure research

Taylor, H. E., Calantone, N. A. & D'Aquila, R. T., Nov 28 2018, In : AIDS (London, England). 32, 18, p. 2847-2851 5 p.

Research output: Contribution to journalArticle

1 Scopus citations
3 Scopus citations

Systemic inflammation is elevated among both HIV-uninfected and -infected young men who have sex with men

Morgan, E., Taylor, H. E., Ryan, D. T., D'Aquila, R. & Mustanski, B., Nov 27 2018, In : AIDS (London, England).

Research output: Contribution to journalArticle

2017

Determinants of HIV Phylogenetic Clustering in Chicago among Young Black Men Who Have Sex with Men from the uConnect Cohort

Morgan, E., Nyaku, A. N., D'Aquila, R. T. & Schneider, J. A., Jul 1 2017, In : Journal of Acquired Immune Deficiency Syndromes. 75, 3, p. 265-270 6 p.

Research output: Contribution to journalArticle

7 Scopus citations

Preferences for Long-Acting Pre-exposure Prophylaxis (PrEP), Daily Oral PrEP, or Condoms for HIV Prevention Among U.S. Men Who Have Sex with Men

Greene, G. J., Swann, G., Fought, A. J., Carballo-Diéguez, A., Hope, T. J., Kiser, P. F., Mustanski, B. & D’Aquila, R. T., May 1 2017, In : AIDS and behavior. 21, 5, p. 1336-1349 14 p.

Research output: Contribution to journalArticle

44 Scopus citations
2015

Genetic analysis of the localization of APOBEC3F to human immunodeficiency virus type 1 virion cores

Donahue, J. P., Levinson, R. T., Sheehan, J. H., Sutton, L., Taylor, H. E., Meiler, J., D'Aquila, R. T. & Song, C., Jan 1 2015, In : Journal of virology. 89, 4, p. 2415-2424 10 p.

Research output: Contribution to journalArticle

4 Scopus citations

Phospholipase D1 Couples CD4+ T Cell Activation to c-Myc-Dependent Deoxyribonucleotide Pool Expansion and HIV-1 Replication

Taylor, H. E., Simmons, G. E., Mathews, T. P., Khatua, A. K., Popik, W., Lindsley, C. W., D’Aquila, R. T. & Brown, H. A., May 1 2015, In : PLoS pathogens. 11, 5, e1004864.

Research output: Contribution to journalArticle

20 Scopus citations
2014

Current drug use and lack of HIV virologic suppression: Point-of-care urine drug screen versus self-report

Qian, H. Z., Mitchell, V. J., Bebawy, S., Cassell, H., Perez, G., McGowan, C. C., Sterling, T. R., Vermund, S. H., D'Aquila, R. & Hulgan, T., Sep 18 2014, In : BMC Infectious Diseases. 14, 1, 508.

Research output: Contribution to journalArticle

9 Scopus citations
7 Scopus citations

HIV-1 RNA levels and antiretroviral drug resistance in blood and non-blood compartments from HIV-1-infected men and women enrolled in AIDS clinical trials group study A5077

Kantor, R., Bettendorf, D., Bosch, R. J., Mann, M., Katzenstein, D., Cu-Uvin, S., D'Aquila, R., Frenkel, L., Fiscus, S. & Coombs, R., Apr 3 2014, In : PloS one. 9, 4, e93537.

Research output: Contribution to journalArticle

8 Scopus citations
2013

Lower HIV Provirus Levels Are Associated with More APOBEC3G Protein in Blood Resting Memory CD4+ T Lymphocytes of Controllers In Vivo

de Pasquale, M. P., Kourteva, Y., Allos, T. & D'Aquila, R. T., Oct 16 2013, In : PloS one. 8, 10, e76002.

Research output: Contribution to journalArticle

15 Scopus citations

Persistent genital tract HIV-1 RNA shedding after change in treatment regimens in antiretroviral-experienced women with detectable plasma viral load

Venkatesh, K. K., Delong, A. K., Kantor, R., Chapman, S., Ingersoll, J., Kurpewski, J., De Pasquale, M. P., D'Aquila, R. T., Caliendo, A. M. & Cu-Uvin, S., Apr 1 2013, In : Journal of Women's Health. 22, 4, p. 330-338 9 p.

Research output: Contribution to journalArticle

7 Scopus citations
2012

Apobec3g complexes decrease human immunodeficiency virus type 1 production

Martin, K. L., Johnson, M. & D'Aquila, R. T., Aug 1 2012, In : Journal of virology. 86, 16, p. 8916 1 p.

Research output: Contribution to journalComment/debate

1 Scopus citations

APOBEC3G expression and hypermutation are inversely associated with human immunodeficiency virus type 1 (HIV-1) burden in vivo

Kourteva, Y., De Pasquale, M., Allos, T., McMunn, C. & D'Aquila, R. T., Aug 15 2012, In : Virology. 430, 1, p. 1-9 9 p.

Research output: Contribution to journalArticle

30 Scopus citations

No effect of raltegravir intensification on viral replication markers in the blood of HIV-1-infected patients receiving antiretroviral therapy

Gandhi, R. T., Coombs, R. W., Chan, E. S., Bosch, R. J., Zheng, L., Margolis, D. M., Read, S., Kallungal, B., Chang, M., Goecker, E. A., Wiegand, A., Kearney, M., Jacobson, J. M., D'Aquila, R., Lederman, M. M., Mellors, J. W. & Eron, J. J., Mar 1 2012, In : Journal of Acquired Immune Deficiency Syndromes. 59, 3, p. 229-235 7 p.

Research output: Contribution to journalArticle

86 Scopus citations

Risk factors for symptomatic hyperlactatemia and lactic acidosis among combination antiretroviral therapy-treated adults in Botswana: Results from a clinical trial

Wester, C. W., Eden, S. K., Shepherd, B. E., Bussmann, H., Novitsky, V., Samuels, D. C., Hendrickson, S. L., Winkler, C. A., O'Brien, S. J., Essex, M., D'Aquila, R. T., Degruttola, V. & Marlink, R. G., Aug 1 2012, In : AIDS research and human retroviruses. 28, 8, p. 759-765 7 p.

Research output: Contribution to journalArticle

13 Scopus citations

Signals in APOBEC3F N-terminal and C-terminal deaminase domains each contribute to encapsidation in HIV-1 virions and are both required for HIV-1 restriction

Song, C., Sutton, L., Johnson, M. E., D'Aquila, R. T. & Donahue, J. P., May 11 2012, In : Journal of Biological Chemistry. 287, 20, p. 16965-16974 10 p.

Research output: Contribution to journalArticle

17 Scopus citations

T cell activation markers and African mitochondrial DNA Haplogroups among non-hispanic black participants in AIDS clinical trials group study 384

Hulgan, T., Robbins, G. K., Kalams, S. A., Samuels, D. C., Grady, B., Shafer, R., Murdock, D. G., Selph, D., Haas, D. W., Pollard, R. B., de Gruttola, V., Snyder, S., Nevin, T., Pettinelli, C., Dube, M., Fischl, M., Delaphna, R., Gideon, L., D'Aquila, R., Vella, S. & 2 others, Merigan, T. & Hirsch, M., Aug 27 2012, In : PloS one. 7, 8, e43803.

Research output: Contribution to journalArticle

4 Scopus citations
2011

APOBEC3G complexes decrease human immunodeficiency virus type 1 production

Martin, K. L., Johnson, M. & D'Aquila, R. T., Sep 1 2011, In : Journal of virology. 85, 18, p. 9314-9326 13 p.

Research output: Contribution to journalArticle

13 Scopus citations

Filamin A protein interacts with human immunodeficiency virus type 1 Gag protein and contributes to productive particle assembly

Cooper, J., Liu, L., Woodruff, E. A., Taylor, H. E., Goodwin, J. S., D'Aquila, R. T., Spearman, P., Hildreth, J. E. K. & Dong, X., Aug 12 2011, In : Journal of Biological Chemistry. 286, 32, p. 28498-28510 13 p.

Research output: Contribution to journalArticle

27 Scopus citations

Tenofovir (TDF)-selected or abacavir (ABC)-selected low-frequency HIV type 1 subpopulations during failure with persistent viremia as detected by ultradeep pyrosequencing

D'Aquila, R. T., Geretti, A. M., Horton, J. H., Rouse, E., Kheshti, A., Raffanti, S., Oie, K., Pappa, K. & Ross, L. L., Feb 1 2011, In : AIDS research and human retroviruses. 27, 2, p. 201-209 9 p.

Research output: Contribution to journalArticle

15 Scopus citations
2010

Genital tract HIV-1 RNA shedding among women with below detectable plasma viral load

Cu-Uvin, S., DeLong, A. K., Venkatesh, K. K., Hogan, J. W., Ingersoll, J., Kurpewski, J., De Pasquale, M. P., D'Aquila, R. & Caliendo, A. M., Oct 23 2010, In : AIDS. 24, 16, p. 2489-2497 9 p.

Research output: Contribution to journalArticle

93 Scopus citations

Pre-existing minority drug-resistant HIV-1 variants, adherence, and risk of antiretroviral treatment failure

Paredes, R., Lalama, C. M., Ribaudo, H. J., Schackman, B. R., Shikuma, C., Gigue, F., Meyer, W. A., Johnson, V. A., Fiscus, S. A., D'Aquila, R. T., Gulick, R. M. & Kuritzkes, D. R., Mar 1 2010, In : Journal of Infectious Diseases. 201, 5, p. 662-671 10 p.

Research output: Contribution to journalArticle

155 Scopus citations

Workshop on immunizations in older adults: Identifying future research agendas

High, K. P., D'Aquila, R. T., Fuldner, R. A., Gerding, D. N., Halter, J. B., Haynes, L., Hazzard, W. R., Jackson, L. A., Janoff, E., Levin, M. J., Nayfield, S. G., Nichol, K. L., Prabhudas, M., Talbot, H. K., Clayton, C. P., Henderson, R., Scott, C. M., Tarver, E. D., Woolard, N. F. & Schmader, K. E., Apr 1 2010, In : Journal of the American Geriatrics Society. 58, 4, p. 765-776 12 p.

Research output: Contribution to journalReview article

13 Scopus citations
2009
21 Scopus citations

Differences in APOBEC3G expression in CD4+ T helper lymphocyte subtypes modulate HIV-1 infectivity

Vetter, M. L., Johnson, M. E., Antons, A. K., Unutmaz, D. & D'Aquila, R. T., Feb 2009, In : PLoS pathogens. 5, 2, e1000292.

Research output: Contribution to journalArticle

34 Scopus citations

Reply to amendola et al.

Rebeiro, P., Tang, Y. W., Sterling, T. R., Raffanti, S. P. & D'Aquila, R. T., Jun 1 2009, In : Clinical Infectious Diseases. 48, 11, p. 1631-1632 2 p.

Research output: Contribution to journalLetter

2008

Dynamics of total, linear nonintegrated, and integrated HIV-1 DNA in vivo and in vitro

Koelsch, K. K., Liu, L., Haubrich, R., May, S., Havlir, D., Günthard, H. F., Ignacio, C. C., Campos-Soto, P., Little, S. J., Shafer, R., Robbins, G. K., D'Aquila, R. T., Kawano, Y., Young, K., Dao, P., Spina, C. A., Richman, D. D. & Wong, J. K., Feb 1 2008, In : Journal of Infectious Diseases. 197, 3, p. 411-419 9 p.

Research output: Contribution to journalArticle

120 Scopus citations

Increased detectability of plasma HIV-1 RNA after introduction of a new assay and altered specimen-processing procedures

Rebeiro, P. F., Kheshti, A., Bebawy, S. S., Stinnette, S. E., Erdem, H., Tang, Y. W., Sterling, T. R., Raffanti, S. P. & D'Aquila, R. T., Nov 15 2008, In : Clinical Infectious Diseases. 47, 10, p. 1354-1357 4 p.

Research output: Contribution to journalArticle

25 Scopus citations

Preexisting resistance to nonnucleoside reverse-transcriptase inhibitors predicts virologic failure of an efavirenz-based regimen in treatment-naive HIV-1-infected subjects

Kuritzkes, D. R., Lalama, C. M., Ribaudo, H. J., Marcial, M., Meyer, W. A., Shikuma, C., Johnson, V. A., Fiscus, S. A., D'Aquila, R. T., Schackman, B. R., Acosta, E. P. & Gulick, R. M., Mar 15 2008, In : Journal of Infectious Diseases. 197, 6, p. 867-870 4 p.

Research output: Contribution to journalArticle

127 Scopus citations

Survival, plasma HIV-1 RNA concentrations and drug resistance in HIV-1-infected Haitian adolescents and young adults on antiretrovirals

Charles, M., Noel, F., Leger, P., Severe, P., Riviere, C., Beauharnais, C. A., Miller, E., Rutledge, J., Bang, H., Shealey, W., D'Aquila, R. T., Gulick, R. M., Johnson, W. D., Wright, P. F., Pape, J. W. & Fitzgerald, D. W., Dec 2008, In : Bulletin of the World Health Organization. 86, 12, p. 970-977 8 p.

Research output: Contribution to journalArticle

32 Scopus citations

The HIV-1 Vif PPLP motif is necessary for human APOBEC3G binding and degradation

Donahue, J. P., Vetter, M. L., Mukhtar, N. A. & D'Aquila, R. T., Jul 20 2008, In : Virology. 377, 1, p. 49-53 5 p.

Research output: Contribution to journalArticle

54 Scopus citations
2006

Immunogenetics of CD4 lymphocyte count recovery during antiretroviral therapy: An AIDS clinical trials group study

Haas, D. W., Geraghty, D. E., Andersen, J., Mar, J., Motsinger, A. A., D'Aquila, R. T., Unutmaz, D., Benson, C. A., Ritchie, M. D. & Landay, A., Oct 15 2006, In : Journal of Infectious Diseases. 194, 8, p. 1098-1107 10 p.

Research output: Contribution to journalArticle

60 Scopus citations

Multilocus genetic interactions and response to efavirenz-containing regimens: An Adult AIDS Clinical Trials Group study

Motsinger, A. A., Ritchie, M. D., Shafer, R. W., Robbins, G. K., Morse, G. D., Labbé, L., Wilkinson, G. R., Clifford, D. B., D'Aquila, R. T., Johnson, V. A., Pollard, R. B., Merigan, T. C., Hirsch, M. S., Donahue, J. P., Kim, R. B. & Haas, D. W., Nov 1 2006, In : Pharmacogenetics and genomics. 16, 11, p. 837-845 9 p.

Research output: Contribution to journalArticle

59 Scopus citations
2005

Pharmacogenetics of long-term responses to antiretroviral regimens containing efavirenz and/or nelfinavir: An adult AIDS clinical trials group study

Haas, D. W., Smeaton, L. M., Shafer, R. W., Robbins, G. K., Morse, G. D., Labbé, L., Wilkinson, G. R., Clifford, D. B., D'Aquila, R. T., De Gruttola, V., Pollard, R. B., Merigan, T. C., Hirsch, M. S., George, A. L., Donahue, J. P. & Kim, R. B., Dec 1 2005, In : Journal of Infectious Diseases. 192, 11, p. 1931-1942 12 p.

Research output: Contribution to journalArticle

218 Scopus citations
2004

Effect of persistent moderate viremia on disease progression during HIV therapy

Raffanti, S. P., Fusco, J. S., Sherrill, B. H., Hansen, N. I., Justice, A. C., D'Aquila, R., Mangialardi, W. J. & Fusco, G. P., Sep 1 2004, In : Journal of Acquired Immune Deficiency Syndromes. 37, SUPPL. 1, p. 1147-1154 8 p.

Research output: Contribution to journalArticle

52 Scopus citations