Richard W Carthew

  • 13420 Citations
1982 …2023
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Personal profile

Research Interests

Our group studies how complex cell and tissue behaviors are elicited within the context of the organism. We work as experimentalists, teaming up with theorists in applied mathematics, physics, and engineering, to apply systematic and quantitative approaches to biological problems. Gene regulation is of particular interest, and we have a long-standing interest in why non-coding RNAs regulate gene expression.

Education/Academic qualification

Biology, PhD, Massachusetts Institute of Technology

… → 1987

Botany, MSc, University of Toronto

… → 1980

Biology, BSc, Queens University, Kingston, Canada

… → 1978

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Drosophila Medicine & Life Sciences
MicroRNAs Medicine & Life Sciences
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Genes Medicine & Life Sciences
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Double-Stranded RNA Medicine & Life Sciences
RNA-Induced Silencing Complex Medicine & Life Sciences
Proteins Medicine & Life Sciences

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Grants 2003 2023

growth and development
Biological Sciences
mathematical models
fruit flies
Biological Science Disciplines
Competitive Bidding
Foster Home Care

Research Output 1982 2019

Repressive Gene Regulation Synchronizes Development with Cellular Metabolism

Cassidy, J. J., Bernasek, S. M., Bakker, R., Giri, R., Peláez, N., Eder, B., Bobrowska, A., Bagheri, N., Amaral, L. A. N. & Carthew, R. W., Aug 8 2019, In : Cell. 178, 4, p. 980-992 13 p.

Research output: Contribution to journalArticle

Gene expression
Gene Regulatory Networks
Developmental Genes
6 Citations (Scopus)

Microprocessor Recruitment to Elongating RNA Polymerase II Is Required for Differential Expression of MicroRNAs

Church, V. A., Pressman, S., Isaji, M., Truscott, M., Cizmecioglu, N. T., Buratowski, S., Frolov, M. V. & Carthew, R. W., Sep 26 2017, In : Cell reports. 20, 13, p. 3123-3134 12 p.

Research output: Contribution to journalArticle

RNA Polymerase II
Microprocessor chips
14 Citations (Scopus)

MicroRNA function in Drosophila melanogaster

Carthew, R. W., Agbu, P. & Giri, R., May 1 2017, In : Seminars in Cell and Developmental Biology. 65, p. 29-37 9 p.

Research output: Contribution to journalReview article

Drosophila melanogaster
Gene Regulatory Networks
Germ Cells
3 Citations (Scopus)

MicroRNAs Make a Difference in Cardiovascular Robustness

Bakker, R. & Carthew, R. W., Mar 27 2017, In : Developmental Cell. 40, 6, p. 515-516 2 p.

Research output: Contribution to journalShort survey

Embryonic Development
1 Citation (Scopus)

Out of the testis: Biological impacts of new genes

Nyberg, K. G. & Carthew, R. W., Sep 15 2017, In : Genes and Development. 31, 18, p. 1825-1826 2 p.

Research output: Contribution to journalArticle

Clustered Regularly Interspaced Short Palindromic Repeats
Molecular Dynamics Simulation