Grants per year
Personal profile
Research Interests
Our group studies how complex cell and tissue behaviors are elicited within the context of the organism. We work as experimentalists, teaming up with theorists in applied mathematics, physics, and engineering, to apply systematic and quantitative approaches to biological problems. Gene regulation is of particular interest, and we have a long-standing interest in why non-coding RNAs regulate gene expression.
Education/Academic qualification
Biology, PhD, Massachusetts Institute of Technology
… → 1987
Botany, MSc, University of Toronto
… → 1980
Biology, BSc, Queen's University Kingston
… → 1978
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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National Institute for Theory and Mathematics in Biology
Carthew, R. W., Auffinger, A., Braun, R. I. & Kath, W. L.
9/15/23 → 8/31/28
Project: Research project
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National Institute for Theory and Mathematics in Bilogy
Carthew, R. W., Braun, R. I. & Kath, W. L.
7/1/23 → 6/30/28
Project: Research project
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REU Site: Quantitative Biology REU (QBREU) at Northwestern University
Braun, R. I., Braun, R. I., Andersen, E. C., Andersen, E. C., Allada, R., Allada, R., Auffinger, A., Auffinger, A., Carthew, R. W., Carthew, R. W., Kath, W. L., Kath, W. L., Kovacs, I., Kovacs, I., LaBonne, C., LaBonne, C., Lane, K. M., Lane, K. M., Mangan, N. M., Mangan, N. M., Mani, M., Mani, M., Wang, J. & Wang, J.
4/15/22 → 3/31/25
Project: Research project
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Non-coding RNAs and their mechanisms and functions
Carthew, R. W. & Carthew, R. W.
National Institute of General Medical Sciences
4/1/21 → 3/31/26
Project: Research project
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Northwestern University Quantitative Biology Center (NUQuB)
Carthew, R. W., Allada, R., Amaral, L. A. N., Andersen, E. C., Auffinger, A., Bagheri, N., Braun, R. I., Kath, W. L., LaBonne, C., Mangan, N. M., Mani, M., Wang, J., Wang, X. & Goldberg, B. B.
7/1/18 → 6/30/24
Project: Research project
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Ratiometric sensing of Pnt and Yan transcription factor levels confers ultrasensitivity to photoreceptor fate transitions in Drosophila
Bernasek, S. M., Hur, S. S. J., Peláez-Restrepo, N., Lachance, J. F. B., Bakker, R., Navarro, H. T., Sanchez-Luege, N., Amaral, L. A. N., Bagheri, N., Rebay, I. & Carthew, R. W., Apr 2023, In: Development (Cambridge). 150, 8, dev201467.Research output: Contribution to journal › Article › peer-review
Open Access -
CRISPR-/Cas9-Mediated Precise and Efficient Genome Editing in Drosophila
Nyberg, K. G. & Carthew, R. W., 2022, Methods in Molecular Biology. Humana Press Inc., p. 135-156 22 p. (Methods in Molecular Biology; vol. 2540).Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Emergence of a geometric pattern of cell fates from tissue-scale mechanics in the Drosophila eye
Gallagher, K. D., Mani, M. & Carthew, R. W., Jan 2022, In: eLife. 11, e72806.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
Invading viral DNA triggers dsRNA synthesis by RNA polymerase II to activate antiviral RNA interference in Drosophila
de Faria, I. J. S., Aguiar, E. R. G. R., Olmo, R. P., Alves da Silva, J., Daeffler, L., Carthew, R. W., Imler, J. L. & Marques, J. T., Jun 21 2022, In: Cell reports. 39, 12, 110976.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
Single-cell Senseless protein analysis reveals metastable states during the transition to a sensory organ fate
Giri, R., Brady, S., Papadopoulos, D. K. & Carthew, R. W., Oct 21 2022, In: iScience. 25, 10, 105097.Research output: Contribution to journal › Article › peer-review
Open Access
Datasets
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Microprocessor recruitment to elongating RNA Polymerase II is required for differential expression of microRNAs
Church, V. A. (Contributor) & Carthew, R. W. (Contributor), Gene Expression Omnibus, Aug 29 2017
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE103234
Dataset
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A pipeline for precise and efficient genome editing by sgRNA-Cas9 RNPs in Drosophila
Nyberg, K. G. (Creator), Nguyen, J. Q. (Creator), Kwon, Y. (Contributor), Blythe, S. (Creator), Beitel, G. J. (Creator) & Carthew, R. W. (Creator), Taylor & Francis, 2020
DOI: 10.6084/m9.figshare.13049813.v3, https://tandf.figshare.com/articles/dataset/A_Pipeline_for_Precise_and_Efficient_Genome_Editing_by_sgRNA-Cas9_RNPs_in_i_Drosophila_i_/13049813/3
Dataset