Rimas Vincas Lukas

  • 904 Citations
20052020

Research output per year

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Research Output

2020

Acute Neurological Complications of Brain Tumors and Immune Therapies, a Guideline for the Neuro-hospitalist

Thakkar, J. P., Prabhu, V. C., Rouse, S. & Lukas, R. V., Aug 1 2020, In : Current neurology and neuroscience reports. 20, 8, 32.

Research output: Contribution to journalReview article

Can patient selection and neoadjuvant administration resuscitate PD-1 inhibitors for glioblastoma?

Arrieta, V. A., Iwamoto, F., Lukas, R. V., Sachdev, S., Rabadan, R. & Sonabend, A. M., May 2020, In : Journal of neurosurgery. 132, 5, p. 1667-1672 6 p.

Research output: Contribution to journalArticle

2 Scopus citations

Dermatomyositis in a patient undergoing nivolumab therapy for metastatic melanoma: A case report and review of the literature

Kosche, C., Stout, M., Sosman, J., Lukas, R. V. & Choi, J. N., 2020, (Accepted/In press) In : Melanoma Research. p. 313-316 4 p.

Research output: Contribution to journalArticle

2 Scopus citations

Evaluation of patient education materials for stereotactic radiosurgery from high-performing neurosurgery hospitals and professional societies

Rooney, M. K., Rooney, M. K., Golden, D. W., Byun, J., Lukas, R. V., Lukas, R. V., Lesniak, M. S. & Sachdev, S., Jan 31 2020, In : Neuro-Oncology Practice. 7, 1, p. 59-67 9 p.

Research output: Contribution to journalArticle

Extensive brainstem infiltration, not mass effect, is a common feature of end-stage cerebral glioblastomas

Drumm, M. R., Dixit, K. S., Grimm, S., Kumthekar, P., Lukas, R. V., Raizer, J. J., Stupp, R., Chheda, M. G., Kam, K. L., McCord, M., Sachdev, S., Kruser, T., Steffens, A., Javier, R., McCortney, K. & Horbinski, C., Apr 15 2020, In : Neuro-oncology. 22, 4, p. 470-479 10 p.

Research output: Contribution to journalArticle

Global post-marketing safety surveillance of Tumor Treating Fields (TTFields) in patients with high-grade glioma in clinical practice

Shi, W., Blumenthal, D. T., Oberheim Bush, N. A., Kebir, S., Lukas, R. V., Muragaki, Y., Zhu, J. J. & Glas, M., 2020, (Accepted/In press) In : Journal of Neuro-Oncology.

Research output: Contribution to journalArticle

Open Access

Immunosuppressive IDO in Cancer: Mechanisms of Action, Animal Models, and Targeting Strategies

Zhai, L., Bell, A., Ladomersky, E., Lauing, K. L., Bollu, L., Sosman, J. A., Zhang, B., Wu, J. D., Miller, S. D., Meeks, J. J., Lukas, R. V., Wyatt, E. J., Doglio, L., Schiltz, G. E., McCusker, R. H. & Wainwright, D. A., Jun 16 2020, In : Frontiers in immunology. 11, 1185.

Research output: Contribution to journalReview article

Open Access

Is Next-Generation Sequencing Alone Sufficient to Reliably Diagnose Gliomas?

Kam, K. L., Appin, C. L., Mao, Q., Ikegami, S., Lukas, R. V., Nikiforova, M. N., Roy, S., Brat, D. J. & Horbinski, C., Jul 1 2020, In : Journal of neuropathology and experimental neurology. 79, 7, p. 763-766 4 p.

Research output: Contribution to journalArticle

Leptomeningeal metastasis from solid tumors

Thakkar, J. P., Kumthekar, P., Dixit, K. S., Stupp, R. & Lukas, R. V., Apr 15 2020, In : Journal of the Neurological Sciences. 411, 116706.

Research output: Contribution to journalReview article

1 Scopus citations

Rindopepimut with bevacizumab for patients with relapsed EGFRvIII-expressing glioblastoma (REACT): Results of a double-blind randomized phase II trial

for the ReACT trial investigators, Apr 1 2020, In : Clinical Cancer Research. 26, 7, p. 1586-1594 9 p.

Research output: Contribution to journalArticle

6 Scopus citations
2019

A Report from the 2017 Sino-US Medical Education Symposium in Wuhan, China

Lukas, R., Jiang, I., Lio, J., Cooper, B., Dong, H., Fan, J. & Sherer, R., 2019, In : Education for Health: Change in Learning and Practice. 32, 2, p. 99-100 2 p.

Research output: Contribution to journalLetter

Atezolizumab in patients with advanced non-small cell lung cancer and history of asymptomatic, treated brain metastases: Exploratory analyses of the phase III OAK study

Gadgeel, S. M., Lukas, R. V., Goldschmidt, J., Conkling, P., Park, K., Cortinovis, D., de Marinis, F., Rittmeyer, A., Patel, J. D., von Pawel, J., O'Hear, C., Lai, C., Hu, S., Ballinger, M., Sandler, A., Gandhi, M. & Fehrenbacher, L., Feb 2019, In : Lung Cancer. 128, p. 105-112 8 p.

Research output: Contribution to journalArticle

17 Scopus citations

Author Correction: Immune and genomic correlates of response to anti-PD-1 immunotherapy in glioblastoma (Nature Medicine, (2019), 25, 3, (462-469), 10.1038/s41591-019-0349-y)

Zhao, J., Chen, A. X., Gartrell, R. D., Silverman, A. M., Aparicio, L., Chu, T., Bordbar, D., Shan, D., Samanamud, J., Mahajan, A., Filip, I., Orenbuch, R., Goetz, M., Yamaguchi, J. T., Cloney, M., Horbinski, C., Lukas, R. V., Raizer, J. J., Rae, A. I., Yuan, J. & 7 others, Canoll, P., Bruce, J. N., Saenger, Y. M., Sims, P., Iwamoto, F. M., Sonabend, A. M. & Rabadan, R., Jun 1 2019, In : Nature Medicine. 25, 6, 1 p.

Research output: Contribution to journalComment/debate

Open Access
4 Scopus citations

Commentary: preclinical efficacy of immune-checkpoint monotherapy does not recapitulate corresponding biomarkers-based clinical predictions in glioblastoma by Garg et al. (2017)

Zhai, L., Ladomersky, E., Lauing, K. L., Wu, M., Scholtens, D. M., Savoor, R., Zhang, B., Wu, J. D., Horbinski, C., Lukas, R. V., Binder, D. C. & Wainwright, D. A., Mar 4 2019, In : OncoImmunology. 8, 3, 1548242.

Research output: Contribution to journalComment/debate

Comments

Lukas, R. V., Mar 1 2019, In : Clinical neurosurgery. 84, 3, 1 p.

Research output: Contribution to journalComment/debate

Imaging tryptophan uptake with positron emission tomography in glioblastoma patients treated with indoximod

Lukas, R. V., Juhász, C., Wainwright, D. A., James, C. D., Kennedy, E., Stupp, R. & Lesniak, M. S., Jan 15 2019, In : Journal of Neuro-Oncology. 141, 1, p. 111-120 10 p.

Research output: Contribution to journalArticle

7 Scopus citations

Immune and genomic correlates of response to anti-PD-1 immunotherapy in glioblastoma

Zhao, J., Chen, A. X., Gartrell, R. D., Silverman, A. M., Aparicio, L., Chu, T., Bordbar, D., Shan, D., Samanamud, J., Mahajan, A., Filip, I., Orenbuch, R., Goetz, M., Yamaguchi, J. T., Cloney, M., Horbinski, C., Lukas, R. V., Raizer, J. J., Rae, A. I., Yuan, J. & 7 others, Canoll, P., Bruce, J. N., Saenger, Y. M., Sims, P., Iwamoto, F. M., Sonabend, A. M. & Rabadan, R., Mar 1 2019, In : Nature Medicine. 25, 3, p. 462-469 8 p.

Research output: Contribution to journalLetter

79 Scopus citations

Immunotherapy Against Gliomas: is the Breakthrough Near?

Lukas, R. V., Wainwright, D. A., Horbinski, C. M., Iwamoto, F. M. & Sonabend, A. M., Nov 1 2019, In : Drugs. 79, 17, p. 1839-1848 10 p.

Research output: Contribution to journalReview article

2 Scopus citations

Improving survival in molecularly selected glioblastoma

Stupp, R., Lukas, R. V. & Hegi, M. E., Feb 16 2019, In : The Lancet. 393, 10172, p. 615-617 3 p.

Research output: Contribution to journalComment/debate

5 Scopus citations

Neurooncology Research in Nigeria: Great Untapped Potential

Adekanmbi, A., Peters, K. B., Razis, E., Adeolu, A. A., Lukas, R. V. & Balogun, J. A., Apr 2019, In : World neurosurgery. 124, p. 381-385 5 p.

Research output: Contribution to journalArticle

1 Scopus citations

Newly diagnosed glioblastoma: A review on clinical management

Lukas, R. V., Wainwright, D. A., Ladomersky, E., Sachdev, S., Sonabend Worthalter, A. M. & Stupp, R., Jan 1 2019, In : ONCOLOGY (United States). 33, 3, p. 91-100 10 p.

Research output: Contribution to journalReview article

19 Scopus citations

Regulatable interleukin-12 gene therapy in patients with recurrent high-grade glioma: Results of a phase 1 trial

Chiocca, E. A., Yu, J. S., Lukas, R. V., Solomon, I. H., Ligon, K. L., Nakashima, H., Triggs, D. A., Reardon, D. A., Wen, P., Stopa, B. M., Naik, A., Rudnick, J., Hu, J. L., Kumthekar, P., Yamini, B., Buck, J. Y., Demars, N., Barrett, J. A., Gelb, A. B., Zhou, J. & 2 others, Lebel, F. & Cooper, L. J. N., Aug 14 2019, In : Science translational medicine. 11, 505, eaaw5680.

Research output: Contribution to journalArticle

17 Scopus citations
Open Access
12 Scopus citations

The interplay among psychological distress, the immune system, and brain tumor patient outcomes

Otto-Meyer, S., Lumibao, J., Kim, E., Ladomersky, E., Zhai, L., Lauing, K. L., Scholtens, D. M., Penedo, F., Amidei, C., Lukas, R. V. & Wainwright, D. A., Aug 2019, In : Current Opinion in Behavioral Sciences. 28, p. 44-50 7 p.

Research output: Contribution to journalReview article

1 Scopus citations

The medical necessity of advanced molecular testing in the diagnosis and treatment of brain tumor patients

Horbinski, C., Ligon, K. L., Brastianos, P., Huse, J. T., Venere, M., Chang, S., Buckner, J., Cloughesy, T., Jenkins, R. B., Giannini, C., Nabors, L. B., Wen, P. Y., Aldape, K. J., Lukas, R. V., Galanis, E., Eberhart, C. G., Brat, D. J. & Sarkaria, J. N., Dec 1 2019, In : Neuro-oncology. 21, 12, p. 1498-1508 11 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations
2018

An overview of meningiomas

Buerki, R. A., Horbinski, C. M., Kruser, T., Horowitz, P. M., James, C. D. & Lukas, R. V., Sep 2018, In : Future Oncology. 14, 21, p. 2161-2177 17 p.

Research output: Contribution to journalReview article

19 Scopus citations

Antiglutamic acid decarboxylase 65 (GAD65) antibody-associated epilepsy

Daif, A., Lukas, R. V., Issa, N. P., Javed, A., VanHaerents, S. A., Reder, A. T., Tao, J. X., Warnke, P., Rose, S., Towle, V. L. & Wu, S., Mar 1 2018, In : Epilepsy and Behavior. 80, p. 331-336 6 p.

Research output: Contribution to journalReview article

20 Scopus citations

A survey of the neuro-oncology landscape

Lukas, R. V., Wu, J., Dey, M., Buerki, R. A., Byrne, R. W. & Dohrmann, G. J., Jan 2018, In : Journal of Clinical Neurology (Korea). 14, 1, p. 8-15 8 p.

Research output: Contribution to journalReview article

1 Scopus citations

BRAF inhibition with concomitant tumor treating fields for a multiply progressive pleomorphic xanthoastrocytoma

Lukas, R. V. & Merrell, R. T., Apr 1 2018, In : CNS oncology. 7, 2, p. CNS10

Research output: Contribution to journalArticle

Clinical activity and safety of atezolizumab in patients with recurrent glioblastoma

Lukas, R. V., Rodon, J., Becker, K., Wong, E. T., Shih, K., Touat, M., Fassò, M., Osborne, S., Molinero, L., O’Hear, C., Grossman, W. & Baehring, J., Nov 15 2018, In : Journal of Neuro-Oncology. 140, 2, p. 317-328 12 p.

Research output: Contribution to journalArticle

22 Scopus citations

Delayed leptomeningeal metastasis of an adult anaplastic pilocytic astrocytoma

Grahnke, K. A., Heiferman, D. M., Borys, E., Melian, E., Barton, K. P., Lukas, R. V., Shaikh, N., Leonetti, J. P. & Anderson, D. E., Apr 1 2018, In : Brain Tumor Pathology. 35, 2, p. 123-126 4 p.

Research output: Contribution to journalLetter

1 Scopus citations

Diagnostic Evaluation in Primary CNS Lymphoma

Lukas, R. V., Riedell, P., Horowitz, P. M., Pytel, P. & Kamson, D. O., Jan 1 2018, In : Neurologist. 23, 2, p. 53-54 2 p.

Research output: Contribution to journalArticle

2 Scopus citations

Hospital volume and group expertise in newly diagnosed glioblastoma management

Lukas, R. V., Lesniak, M. S. & Stupp, R., Jan 1 2018, In : Journal of Neuro-Oncology. 136, 1, p. 213-214 2 p.

Research output: Contribution to journalLetter

1 Scopus citations

IDO1 inhibition synergizes with radiation and PD-1 blockade to durably increase survival against advanced glioblastoma

Ladomersky, E., Zhai, L., Lenzen, A., Lauing, K. L., Qian, J., Scholtens, D. M., Gritsina, G., Sun, X., Liu, Y., Yu, F., Gong, W., Liu, Y., Jiang, B., Tang, T., Patel, R., Platanias, L. C., David James, C., Stupp, R., Lukas, R. V., Binder, D. C. & 1 others, Wainwright, D. A., Jun 1 2018, In : Clinical Cancer Research. 24, 11, p. 2559-2573 15 p.

Research output: Contribution to journalArticle

34 Scopus citations

Lessons learned from rindopepimut treatment in patients with EGFRvIII-expressing glioblastoma

Binder, D. C., Ladomersky, E., Lenzen, A., Zhai, L., Lauing, K. L., Otto-Meyer, S. D., Lukas, R. V. & Wainwright, D. A., Apr 1 2018, In : Translational Cancer Research. 7, p. S510-S513

Research output: Contribution to journalEditorial

3 Scopus citations

Modeling the diffusion of D-2-hydroxyglutarate from IDH1 mutant gliomas in the central nervous system

Linninger, A., Hartung, G. A., Liu, B. P., Mirkov, S., Tangen, K., Lukas, R. V., Unruh, D., David James, C., Sarkaria, J. N. & Horbinski, C., Jan 1 2018, In : Neuro-oncology. 20, 9, p. 1197-1206 10 p.

Research output: Contribution to journalArticle

7 Scopus citations

Neurosciences Continuing Education: An Adult with New-Onset Seizures

Lukas, R. V., Apr 1 2018, In : Journal of Neuroscience Nursing. 50, 2, p. 100-101 2 p.

Research output: Contribution to journalArticle

Primary central nervous system lymphoma: Part 2: Modern therapeutic management and future directions

Lukas, R. V., Gondi, V., Stupp, R. & Raizer, J. J., Jan 1 2018, In : ONCOLOGY (United States). 32, 2, p. e11-e19

Research output: Contribution to journalArticle

2 Scopus citations

Primary central nervous system lymphoma: Part 1: Epidemiology, diagnosis, staging, and prognosis

Lukas, R. V., Stupp, R., Gondi, V. & Raizer, J. J., Jan 1 2018, In : ONCOLOGY (United States). 32, 1, p. 17-27 11 p.

Research output: Contribution to journalArticle

11 Scopus citations

Reader response: Education Research: Difficult conversations in neurology: Lessons learned from medical students

Lukas, R. V., Sep 25 2018, In : Neurology. 91, 13, p. 635-636 2 p.

Research output: Contribution to journalComment/debate

Response to BRAF/MEK inhibition after progression with BRAF inhibition in a patient with anaplastic pleomorphic xanthoastrocytoma

Hussain, F., Horbinski, C. M., Chmura, S. J., Yamini, B. & Lukas, R. V., Sep 1 2018, In : Neurologist. 23, 5, p. 163-166 4 p.

Research output: Contribution to journalArticle

1 Scopus citations
2017

Ambulatory training in neurology education

Lukas, R. V., Blood, A. D., Brorson, J. R. & Albert, D. V. F., Jan 15 2017, In : Journal of the Neurological Sciences. 372, p. 506-509 4 p.

Research output: Contribution to journalComment/debate

1 Scopus citations

Buzz Juice: Neurological sequelae of synthetic cannabinoids

Kak, M., Mikhail, F., Yano, S. T., Guan, R. & Lukas, R. V., Mar 1 2017, In : Journal of Clinical Neuroscience. 37, p. 43 1 p.

Research output: Contribution to journalArticle

2 Scopus citations

CNS hemangioblastomatosis in a patient without von Hippel-Lindau disease

Franco, A., Pytel, P., Lukas, R. V., Chennamaneni, R. & Collins, J. M., Apr 1 2017, In : CNS oncology. 6, 2, p. 101-105 5 p.

Research output: Contribution to journalArticle

1 Scopus citations

Impact of treatment variability on survival in immune-competent and immune- compromised patients with primary central nervous system lymphoma

Karmali, R., Nabhan, C., Petrich, A., Raizer, J., Peace, D., Lukas, R., Gordon, L., Basu, S., Chuakkapalli, V. & Venugopal, P., Apr 2017, In : British Journal of Haemotology. 177, 1, p. 72-79 8 p.

Research output: Contribution to journalArticle

Impact of treatment variability on survival in immuno-competent and immuno-compromised patients with primary central nervous lymphoma

Karmali, R., Nabhan, C., Petrich, A. M., Raizer, J., Peace, D., Lukas, R., Gordon, L. I., Basu, S., Chukkapalli, V. & Venugopal, P., Apr 1 2017, In : British Journal of Haematology. 177, 1, p. 72-79 8 p.

Research output: Contribution to journalArticle

7 Scopus citations

Management of glioblastoma in elderly patients

Young, J. S., Chmura, S. J., Wainwright, D. A., Yamini, B., Peters, K. B. & Lukas, R. V., Sep 15 2017, In : Journal of the Neurological Sciences. 380, p. 250-255 6 p.

Research output: Contribution to journalReview article

11 Scopus citations

Nervous system complications of cancer

Lukas, R. V., Jan 6 2017, Practical Neurology: Fifth Edition. Wolters Kluwer Health Pharma Solutions (Europe) Ltd, p. 822-835 14 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Nervous System Complications of Cancer

Lukas, RV., 2017, Practical Neurology, 5th Edition. Biller, J. (ed.). Baltimore: LWW

Research output: Chapter in Book/Report/Conference proceedingChapter