Rimas Vincas Lukas

  • 679 Citations
20052023
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Research Output 2005 2019

2019

A Report from the 2017 Sino-US Medical Education Symposium in Wuhan, China

Lukas, R., Jiang, I., Lio, J., Cooper, B., Dong, H., Fan, J. & Sherer, R., Jan 1 2019, In : Education for Health: Change in Learning and Practice. 32, 2, p. 99-100 2 p.

Research output: Contribution to journalLetter

6 Citations (Scopus)

Atezolizumab in patients with advanced non-small cell lung cancer and history of asymptomatic, treated brain metastases: Exploratory analyses of the phase III OAK study

Gadgeel, S. M., Lukas, R. V., Goldschmidt, J., Conkling, P., Park, K., Cortinovis, D., de Marinis, F., Rittmeyer, A., Patel, J. D., von Pawel, J., O'Hear, C., Lai, C., Hu, S., Ballinger, M., Sandler, A., Gandhi, M. & Fehrenbacher, L., Feb 2019, In : Lung Cancer. 128, p. 105-112 8 p.

Research output: Contribution to journalArticle

docetaxel
Non-Small Cell Lung Carcinoma
Neoplasm Metastasis
Brain
Nervous System
2 Citations (Scopus)

Author Correction: Immune and genomic correlates of response to anti-PD-1 immunotherapy in glioblastoma (Nature Medicine, (2019), 25, 3, (462-469), 10.1038/s41591-019-0349-y)

Zhao, J., Chen, A. X., Gartrell, R. D., Silverman, A. M., Aparicio, L., Chu, T., Bordbar, D., Shan, D., Samanamud, J., Mahajan, A., Filip, I., Orenbuch, R., Goetz, M., Yamaguchi, J. T., Cloney, M., Horbinski, C., Lukas, R. V., Raizer, J., Rae, A. I., Yuan, J. & 7 others, Canoll, P., Bruce, J. N., Saenger, Y. M., Sims, P., Iwamoto, F. M., Sonabend, A. M. & Rabadan, R., Jun 1 2019, In : Nature Medicine. 25, 6, 1 p.

Research output: Contribution to journalComment/debate

Open Access
Glioblastoma
Immunotherapy
Medicine

Commentary: preclinical efficacy of immune-checkpoint monotherapy does not recapitulate corresponding biomarkers-based clinical predictions in glioblastoma by Garg et al. (2017)

Zhai, L., Ladomersky, E., Lauing, K. L., Wu, M., Scholtens, D. M., Savoor, R., Zhang, B., Wu, J. D., Horbinski, C., Lukas, R. V., Binder, D. C. & Wainwright, D. A., Mar 4 2019, In : OncoImmunology. 8, 3, 1548242.

Research output: Contribution to journalComment/debate

Glioblastoma
Biomarkers
Computational Biology
Gene Expression
Open Access
Radiosurgery
Multicenter Studies
Melanoma
Phosphotransferases
Retrospective Studies

Comments

Lukas, R. V., Mar 1 2019, In : Clinical neurosurgery. 84, 3, 1 p.

Research output: Contribution to journalComment/debate

5 Citations (Scopus)

Imaging tryptophan uptake with positron emission tomography in glioblastoma patients treated with indoximod

Lukas, R. V., Juhász, C., Wainwright, D. A., James, C. D., Kennedy, E., Stupp, R. & Lesniak, M. S., Jan 15 2019, In : Journal of Neuro-Oncology. 141, 1, p. 111-120 10 p.

Research output: Contribution to journalArticle

Indoleamine-Pyrrole 2,3,-Dioxygenase
Glioblastoma
Tryptophan
Positron-Emission Tomography
temozolomide
34 Citations (Scopus)

Immune and genomic correlates of response to anti-PD-1 immunotherapy in glioblastoma

Zhao, J., Chen, A. X., Gartrell, R. D., Silverman, A. M., Aparicio, L., Chu, T., Bordbar, D., Shan, D., Samanamud, J., Mahajan, A., Filip, I., Orenbuch, R., Goetz, M., Yamaguchi, J. T., Cloney, M., Horbinski, C., Lukas, R. V., Raizer, J., Rae, A. I., Yuan, J. & 7 others, Canoll, P., Bruce, J. N., Saenger, Y. M., Sims, P., Iwamoto, F. M., Sonabend, A. M. & Rabadan, R., Mar 1 2019, In : Nature Medicine. 25, 3, p. 462-469 8 p.

Research output: Contribution to journalLetter

Glioblastoma
Immunotherapy
Tumors
Clonal Evolution
Neoplasms

Immunotherapy Against Gliomas: is the Breakthrough Near?

Lukas, R. V., Wainwright, D. A., Horbinski, C. M., Iwamoto, F. M. & Sonabend, A. M., Nov 1 2019, In : Drugs. 79, 17, p. 1839-1848 10 p.

Research output: Contribution to journalReview article

Glioma
Immunotherapy
Oncolytic Virotherapy
Neoplasms
Genetic Therapy
2 Citations (Scopus)

Improving survival in molecularly selected glioblastoma

Stupp, R., Lukas, R. V. & Hegi, M. E., Feb 16 2019, In : The Lancet. 393, 10172, p. 615-617 3 p.

Research output: Contribution to journalComment/debate

Glioblastoma
1 Citation (Scopus)

Neurooncology Research in Nigeria: Great Untapped Potential

Adekanmbi, A., Peters, K. B., Razis, E., Adeolu, A. A., Lukas, R. V. & Balogun, J. A., Apr 2019, In : World neurosurgery. 124, p. 381-385 5 p.

Research output: Contribution to journalArticle

Nigeria
Research
Publications
Manuscripts
Pituitary Neoplasms
4 Citations (Scopus)

Newly diagnosed glioblastoma: A review on clinical management

Lukas, R. V., Wainwright, D. A., Ladomersky, E., Sachdev, S., Sonabend Worthalter, A. M. & Stupp, R., Jan 1 2019, In : ONCOLOGY (United States). 33, 3, p. 91-100 10 p.

Research output: Contribution to journalReview article

Glioblastoma
Central Nervous System Neoplasms
Standard of Care
Cations
Radiotherapy
4 Citations (Scopus)

Regulatable interleukin-12 gene therapy in patients with recurrent high-grade glioma: Results of a phase 1 trial

Chiocca, E. A., Yu, J. S., Lukas, R. V., Solomon, I. H., Ligon, K. L., Nakashima, H., Triggs, D. A., Reardon, D. A., Wen, P., Stopa, B. M., Naik, A., Rudnick, J., Hu, J. L., Kumthekar, P., Yamini, B., Buck, J. Y., Demars, N., Barrett, J. A., Gelb, A. B., Zhou, J. & 2 others, Lebel, F. & Cooper, L. J. N., Aug 14 2019, In : Science translational medicine. 11, 505, eaaw5680.

Research output: Contribution to journalArticle

Interleukin-12
Glioma
Genetic Therapy
Interferons
Survival
7 Citations (Scopus)
Open Access
Glioblastoma
Immunosuppression
Immunotherapy
Central Nervous System
Incidence
1 Citation (Scopus)

The interplay among psychological distress, the immune system, and brain tumor patient outcomes

Otto-Meyer, S., Lumibao, J., Kim, E., Ladomersky, E., Zhai, L., Lauing, K. L., Scholtens, D. M., Penedo, F., Amidei, C., Lukas, R. V. & Wainwright, D. A., Aug 2019, In : Current Opinion in Behavioral Sciences. 28, p. 44-50 7 p.

Research output: Contribution to journalReview article

Brain Neoplasms
Immune System
Psychology
Phase III Clinical Trials
Glioma

The medical necessity of advanced molecular testing in the diagnosis and treatment of brain tumor patients

Horbinski, C., Ligon, K. L., Brastianos, P., Huse, J. T., Venere, M., Chang, S., Buckner, J., Cloughesy, T., Jenkins, R. B., Giannini, C., Stupp, R., Nabors, L. B., Wen, P. Y., Aldape, K. J., Lukas, R. V., Galanis, E., Eberhart, C. G., Brat, D. J. & Sarkaria, J. N., Dec 17 2019, In : Neuro-oncology. 21, 12, p. 1498-1508 11 p.

Research output: Contribution to journalArticle

Open Access
Brain Neoplasms
Therapeutics
Central Nervous System Neoplasms
Molecular Pathology
Epigenomics
2018
5 Citations (Scopus)

An overview of meningiomas

Buerki, R. A., Horbinski, C. M., Kruser, T., Horowitz, P. M., James, C. D. & Lukas, R. V., Sep 2018, In : Future Oncology. 14, 21, p. 2161-2177 17 p.

Research output: Contribution to journalReview article

Meningioma
Molecular Pathology
Therapeutics
Neoplasms
Radiotherapy
11 Citations (Scopus)

Antiglutamic acid decarboxylase 65 (GAD65) antibody-associated epilepsy

Daif, A., Lukas, R. V., Issa, N. P., Javed, A., VanHaerents, S. A., Reder, A. T., Tao, J. X., Warnke, P., Rose, S., Towle, V. L. & Wu, S., Mar 1 2018, In : Epilepsy and Behavior. 80, p. 331-336 6 p.

Research output: Contribution to journalReview article

Carboxy-Lyases
Glutamate Decarboxylase
Epilepsy
Acids
Antibodies
1 Citation (Scopus)

A survey of the neuro-oncology landscape

Lukas, R. V., Wu, J., Dey, M., Buerki, R. A., Byrne, R. W. & Dohrmann, G. J., Jan 1 2018, In : Journal of Clinical Neurology (Korea). 14, 1, p. 8-15 8 p.

Research output: Contribution to journalReview article

Glioma
Neoplasm Metastasis
Brain
Surveys and Questionnaires
Surgical Oncology

BRAF inhibition with concomitant tumor treating fields for a multiply progressive pleomorphic xanthoastrocytoma

Lukas, R. V. & Merrell, R. T., Apr 1 2018, In : CNS oncology. 7, 2, p. CNS10

Research output: Contribution to journalArticle

Neoplasms
Radiation
Therapeutics
PLX4032
8 Citations (Scopus)

Clinical activity and safety of atezolizumab in patients with recurrent glioblastoma

Lukas, R. V., Rodon, J., Becker, K., Wong, E. T., Shih, K., Touat, M., Fassò, M., Osborne, S., Molinero, L., O’Hear, C., Grossman, W. & Baehring, J., Nov 15 2018, In : Journal of Neuro-Oncology. 140, 2, p. 317-328 12 p.

Research output: Contribution to journalArticle

Glioblastoma
Safety
Neoplasms
Biomarkers
T-Lymphocytes
1 Citation (Scopus)

Delayed leptomeningeal metastasis of an adult anaplastic pilocytic astrocytoma

Grahnke, K. A., Heiferman, D. M., Borys, E., Melian, E., Barton, K. P., Lukas, R. V., Shaikh, N., Leonetti, J. P. & Anderson, D. E., Apr 1 2018, In : Brain Tumor Pathology. 35, 2, p. 123-126 4 p.

Research output: Contribution to journalLetter

Astrocytoma
Neoplasm Metastasis
1 Citation (Scopus)

Diagnostic Evaluation in Primary CNS Lymphoma

Lukas, R. V., Riedell, P., Horowitz, P. M., Pytel, P. & Kamson, D. O., Jan 1 2018, In : Neurologist. 23, 2, p. 53-54 2 p.

Research output: Contribution to journalArticle

Lymphoma
Central Nervous System
Steroids
Biopsy
Neoplasms

Hospital volume and group expertise in newly diagnosed glioblastoma management

Lukas, R. V., Lesniak, M. S. & Stupp, R., Jan 1 2018, In : Journal of Neuro-Oncology. 136, 1, p. 213-214 2 p.

Research output: Contribution to journalLetter

20 Citations (Scopus)

IDO1 inhibition synergizes with radiation and PD-1 blockade to durably increase survival against advanced glioblastoma

Ladomersky, E., Zhai, L., Lenzen, A., Lauing, K. L., Qian, J., Scholtens, D. M., Gritsina, G., Sun, X., Liu, Y., Yu, F., Gong, W., Liu, Y., Jiang, B., Tang, T., Patel, R., Platanias, L. C., David James, C., Stupp, R., Lukas, R. V., Binder, D. C. & 1 others, Wainwright, D. A., Jun 1 2018, In : Clinical Cancer Research. 24, 11, p. 2559-2573 15 p.

Research output: Contribution to journalArticle

Glioblastoma
Radiation
Survival
T-Lymphocytes
Therapeutics
1 Citation (Scopus)

Lessons learned from rindopepimut treatment in patients with EGFRvIII-expressing glioblastoma

Binder, D. C., Ladomersky, E., Lenzen, A., Zhai, L., Lauing, K. L., Otto-Meyer, S. D., Lukas, R. V. & Wainwright, D. A., Apr 1 2018, In : Translational Cancer Research. 7, p. S510-S513

Research output: Contribution to journalEditorial

Glioblastoma
Therapeutics
epidermal growth factor receptor VIII
rindopepimut
6 Citations (Scopus)

Modeling the diffusion of D-2-hydroxyglutarate from IDH1 mutant gliomas in the central nervous system

Linninger, A., Hartung, G. A., Liu, B. P., Mirkov, S., Tangen, K., Lukas, R. V., Unruh, D., David James, C., Sarkaria, J. N. & Horbinski, C., Jan 1 2018, In : Neuro-oncology. 20, 9, p. 1197-1206 10 p.

Research output: Contribution to journalArticle

Glioma
Central Nervous System
Liquid Chromatography
Mass Spectrometry
alpha-hydroxyglutarate

Neurosciences Continuing Education: An Adult with New-Onset Seizures

Lukas, R. V., Apr 1 2018, In : Journal of Neuroscience Nursing. 50, 2, p. 100-101 2 p.

Research output: Contribution to journalArticle

Continuing Education
Neurosciences
Seizures
1 Citation (Scopus)

Primary central nervous system lymphoma: Part 2: Modern therapeutic management and future directions

Lukas, R. V., Gondi, V., Stupp, R. & Raizer, J. J., Jan 1 2018, In : ONCOLOGY (United States). 32, 2, p. e11-e19

Research output: Contribution to journalArticle

Lymphoma
Central Nervous System
Central Nervous System Neoplasms
Therapeutics
Methotrexate
5 Citations (Scopus)

Primary central nervous system lymphoma: Part 1: Epidemiology, diagnosis, staging, and prognosis

Lukas, R. V., Stupp, R., Gondi, V. & Raizer, J. J., Jan 1 2018, In : ONCOLOGY (United States). 32, 1, p. 17-27 11 p.

Research output: Contribution to journalArticle

Lymphoma
Epidemiology
Central Nervous System
Central Nervous System Neoplasms
Central Nervous System Diseases

Reader response: Education Research: Difficult conversations in neurology: Lessons learned from medical students

Lukas, R. V., Sep 25 2018, In : Neurology. 91, 13, p. 635-636 2 p.

Research output: Contribution to journalComment/debate

Neurology
Medical Education
Medical Students
Education
Research
1 Citation (Scopus)

Response to BRAF/MEK inhibition after progression with BRAF inhibition in a patient with anaplastic pleomorphic xanthoastrocytoma

Hussain, F., Horbinski, C. M., Chmura, S. J., Yamini, B. & Lukas, R. V., Sep 1 2018, In : Neurologist. 23, 5, p. 163-166 4 p.

Research output: Contribution to journalArticle

Mitogen-Activated Protein Kinase Kinases
Central Nervous System Neoplasms
Disease Progression
Mutation
PLX4032
2017
1 Citation (Scopus)

Ambulatory training in neurology education

Lukas, R. V., Blood, A. D., Brorson, J. R. & Albert, D. V. F., Jan 15 2017, In : Journal of the Neurological Sciences. 372, p. 506-509 4 p.

Research output: Contribution to journalComment/debate

Neurology
Education
Ambulatory Care
Ambulatory Care Facilities
Neurologists
2 Citations (Scopus)

Buzz Juice: Neurological sequelae of synthetic cannabinoids

Kak, M., Mikhail, F., Yano, S. T., Guan, R. & Lukas, R. V., Mar 1 2017, In : Journal of Clinical Neuroscience. 37, p. 43 1 p.

Research output: Contribution to journalArticle

Cannabinoids
Confusion
Corpus Callosum
Hallucinations
Ataxia
1 Citation (Scopus)

CNS hemangioblastomatosis in a patient without von Hippel-Lindau disease

Franco, A., Pytel, P., Lukas, R. V., Chennamaneni, R. & Collins, J. M., Apr 1 2017, In : CNS oncology. 6, 2, p. 101-105 5 p.

Research output: Contribution to journalArticle

Hemangioblastoma
von Hippel-Lindau Disease
Spine
Memory Disorders
Genetic Testing

Impact of treatment variability on survival in immune-competent and immune- compromised patients with primary central nervous system lymphoma

Karmali, R., Nabhan, C., Petrich, A., Raizer, J., Peace, D., Lukas, R., Gordon, L., Basu, S., Chuakkapalli, V. & Venugopal, P., Apr 2017, In : British Journal of Haemotology. 177, 1, p. 72-79 8 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Impact of treatment variability on survival in immuno-competent and immuno-compromised patients with primary central nervous lymphoma

Karmali, R., Nabhan, C., Petrich, A. M., Raizer, J., Peace, D., Lukas, R., Gordon, L. I., Basu, S., Chukkapalli, V. & Venugopal, P., Apr 1 2017, In : British Journal of Haematology. 177, 1, p. 72-79 8 p.

Research output: Contribution to journalArticle

Lymphoma
Survival
Radiotherapy
Methotrexate
Drug Therapy
10 Citations (Scopus)

Management of glioblastoma in elderly patients

Young, J. S., Chmura, S. J., Wainwright, D. A., Yamini, B., Peters, K. B. & Lukas, R. V., Sep 15 2017, In : Journal of the Neurological Sciences. 380, p. 250-255 6 p.

Research output: Contribution to journalReview article

Glioblastoma
Controlled Clinical Trials
Brain Neoplasms
Geriatrics
Therapeutics

Nervous system complications of cancer

Lukas, R. V., Jan 6 2017, Practical Neurology: Fifth Edition. Wolters Kluwer Health Pharma Solutions (Europe) Ltd, p. 822-835 14 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Nervous System
Neoplasms

Nervous System Complications of Cancer

Lukas, RV., 2017, Practical Neurology, 5th Edition. Biller, J. (ed.). Baltimore: LWW

Research output: Chapter in Book/Report/Conference proceedingChapter

Pausing to reflect in a high-volume clinical milieu

Lukas, R. V. & Albert, D. V. F., Feb 1 2017, In : Perspectives on Medical Education. 6, 1, p. 61-62 2 p.

Research output: Contribution to journalLetter

Open Access
Medical Students
medical student

Perceptions of clinical neurosciences amongst trainees in Wuhan, China.

Lukas, RV., Dong, H., Li, J., Wang, Z., Jiang, I. & Sherer, R., 2017, In : Future Neurology.

Research output: Contribution to journalArticle

Perceptions of clinical neurosciences among trainees in Wuhan, China

Lukas, R. V., Dong, H., Li, J., Wang, Z., Jiang, I. & Sherer, R., May 1 2017, In : Future Neurology. 12, 2, p. 65-70 6 p.

Research output: Contribution to journalArticle

Neurology
Neurosciences
China
Medical Students
Learning
6 Citations (Scopus)
4 Citations (Scopus)

Skin toxicities associated with tumor treating fields: case based review

Lukas, R. V., Ratermann, K. L., Wong, E. T. & Villano, J. L., Dec 1 2017, In : Journal of Neuro-Oncology. 135, 3, p. 593-599 7 p.

Research output: Contribution to journalArticle

temozolomide
Glioblastoma
Skin
Patient Advocacy
Neoplasms
8 Citations (Scopus)

State-of-the-art considerations in small cell lung cancer brain metastases

Lukas, R. V., Gondi, V., Kamson, D. O., Kumthekar, P. U. & Salgia, R., Jan 1 2017, In : Oncotarget. 8, 41, p. 71223-71233 11 p.

Research output: Contribution to journalReview article

Small Cell Lung Carcinoma
Brain Neoplasms
Neoplasm Metastasis
Therapeutics
Epidemiology
10 Citations (Scopus)

Survival and complications of stereotactic radiosurgery

Fetcko, K., Lukas, R. V., Watson, G. A., Zhang, L. & Dey, M., Oct 1 2017, In : Medicine (United States). 96, 43, e8293.

Research output: Contribution to journalReview article

Radiosurgery
Glioma
Disease-Free Survival
Necrosis
Radiation

Trends in neurology fellowship training

Williams, JSA., Hodgson, TS., Goldenberg, FD. & Lukas, RV., Apr 18 2017, In : Neuroimmunology and Neuroinflammation. 4, p. 65-68 4 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Tumor Treating Fields in Neuro-Oncological Practice

Mrugala, M. M., Ruzevick, J., Zlomanczuk, P. & Lukas, R. V., Aug 1 2017, In : Current oncology reports. 19, 8, 53.

Research output: Contribution to journalReview article

Glioblastoma
Neoplasms
Mitosis
Brain Neoplasms
Clinical Trials
1 Citation (Scopus)

Views on Careers in Clinical Neurosciences Among Neurosurgeons and Neurologists in China

Lukas, R. V., Ma, C., Chen, J., Dong, H., Li, J., Wang, Z., Jiang, I., Fu, K. M., Satnarayan, S., Albert, D. V. F. & Sherer, R., Feb 1 2017, In : World Neurosurgery. 98, p. 532-537 6 p.

Research output: Contribution to journalArticle

Neurosciences
China
Physicians
Career Choice
Mentors