Rimas Vincas Lukas

  • 686 Citations
20052023
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Research Output 2005 2019

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2019
6 Citations (Scopus)

Atezolizumab in patients with advanced non-small cell lung cancer and history of asymptomatic, treated brain metastases: Exploratory analyses of the phase III OAK study

Gadgeel, S. M., Lukas, R. V., Goldschmidt, J., Conkling, P., Park, K., Cortinovis, D., de Marinis, F., Rittmeyer, A., Patel, J. D., von Pawel, J., O'Hear, C., Lai, C., Hu, S., Ballinger, M., Sandler, A., Gandhi, M. & Fehrenbacher, L., Feb 2019, In : Lung Cancer. 128, p. 105-112 8 p.

Research output: Contribution to journalArticle

docetaxel
Non-Small Cell Lung Carcinoma
Neoplasm Metastasis
Brain
Nervous System
5 Citations (Scopus)

Imaging tryptophan uptake with positron emission tomography in glioblastoma patients treated with indoximod

Lukas, R. V., Juhász, C., Wainwright, D. A., James, C. D., Kennedy, E., Stupp, R. & Lesniak, M. S., Jan 15 2019, In : Journal of Neuro-Oncology. 141, 1, p. 111-120 10 p.

Research output: Contribution to journalArticle

Indoleamine-Pyrrole 2,3,-Dioxygenase
Glioblastoma
Tryptophan
Positron-Emission Tomography
temozolomide
1 Citation (Scopus)

Neurooncology Research in Nigeria: Great Untapped Potential

Adekanmbi, A., Peters, K. B., Razis, E., Adeolu, A. A., Lukas, R. V. & Balogun, J. A., Apr 2019, In : World neurosurgery. 124, p. 381-385 5 p.

Research output: Contribution to journalArticle

Nigeria
Research
Publications
Manuscripts
Pituitary Neoplasms
4 Citations (Scopus)

Regulatable interleukin-12 gene therapy in patients with recurrent high-grade glioma: Results of a phase 1 trial

Chiocca, E. A., Yu, J. S., Lukas, R. V., Solomon, I. H., Ligon, K. L., Nakashima, H., Triggs, D. A., Reardon, D. A., Wen, P., Stopa, B. M., Naik, A., Rudnick, J., Hu, J. L., Kumthekar, P., Yamini, B., Buck, J. Y., Demars, N., Barrett, J. A., Gelb, A. B., Zhou, J. & 2 others, Lebel, F. & Cooper, L. J. N., Aug 14 2019, In : Science translational medicine. 11, 505, eaaw5680.

Research output: Contribution to journalArticle

Interleukin-12
Glioma
Genetic Therapy
Interferons
Survival
8 Citations (Scopus)
Open Access
Glioblastoma
Immunosuppression
Immunotherapy
Central Nervous System
Incidence

The medical necessity of advanced molecular testing in the diagnosis and treatment of brain tumor patients

Horbinski, C., Ligon, K. L., Brastianos, P., Huse, J. T., Venere, M., Chang, S., Buckner, J., Cloughesy, T., Jenkins, R. B., Giannini, C., Stupp, R., Nabors, L. B., Wen, P. Y., Aldape, K. J., Lukas, R. V., Galanis, E., Eberhart, C. G., Brat, D. J. & Sarkaria, J. N., Dec 17 2019, In : Neuro-oncology. 21, 12, p. 1498-1508 11 p.

Research output: Contribution to journalArticle

Open Access
Brain Neoplasms
Therapeutics
Central Nervous System Neoplasms
Molecular Pathology
Epigenomics
2018

BRAF inhibition with concomitant tumor treating fields for a multiply progressive pleomorphic xanthoastrocytoma

Lukas, R. V. & Merrell, R. T., Apr 1 2018, In : CNS oncology. 7, 2, p. CNS10

Research output: Contribution to journalArticle

Neoplasms
Radiation
Therapeutics
PLX4032
8 Citations (Scopus)

Clinical activity and safety of atezolizumab in patients with recurrent glioblastoma

Lukas, R. V., Rodon, J., Becker, K., Wong, E. T., Shih, K., Touat, M., Fassò, M., Osborne, S., Molinero, L., O’Hear, C., Grossman, W. & Baehring, J., Nov 15 2018, In : Journal of Neuro-Oncology. 140, 2, p. 317-328 12 p.

Research output: Contribution to journalArticle

Glioblastoma
Safety
Neoplasms
Biomarkers
T-Lymphocytes
1 Citation (Scopus)

Diagnostic Evaluation in Primary CNS Lymphoma

Lukas, R. V., Riedell, P., Horowitz, P. M., Pytel, P. & Kamson, D. O., Jan 1 2018, In : Neurologist. 23, 2, p. 53-54 2 p.

Research output: Contribution to journalArticle

Lymphoma
Central Nervous System
Steroids
Biopsy
Neoplasms
21 Citations (Scopus)

IDO1 inhibition synergizes with radiation and PD-1 blockade to durably increase survival against advanced glioblastoma

Ladomersky, E., Zhai, L., Lenzen, A., Lauing, K. L., Qian, J., Scholtens, D. M., Gritsina, G., Sun, X., Liu, Y., Yu, F., Gong, W., Liu, Y., Jiang, B., Tang, T., Patel, R., Platanias, L. C., David James, C., Stupp, R., Lukas, R. V., Binder, D. C. & 1 others, Wainwright, D. A., Jun 1 2018, In : Clinical Cancer Research. 24, 11, p. 2559-2573 15 p.

Research output: Contribution to journalArticle

Glioblastoma
Radiation
Survival
T-Lymphocytes
Therapeutics
6 Citations (Scopus)

Modeling the diffusion of D-2-hydroxyglutarate from IDH1 mutant gliomas in the central nervous system

Linninger, A., Hartung, G. A., Liu, B. P., Mirkov, S., Tangen, K., Lukas, R. V., Unruh, D., David James, C., Sarkaria, J. N. & Horbinski, C., Jan 1 2018, In : Neuro-oncology. 20, 9, p. 1197-1206 10 p.

Research output: Contribution to journalArticle

Glioma
Central Nervous System
Liquid Chromatography
Mass Spectrometry
alpha-hydroxyglutarate

Neurosciences Continuing Education: An Adult with New-Onset Seizures

Lukas, R. V., Apr 1 2018, In : Journal of Neuroscience Nursing. 50, 2, p. 100-101 2 p.

Research output: Contribution to journalArticle

Continuing Education
Neurosciences
Seizures
1 Citation (Scopus)

Primary central nervous system lymphoma: Part 2: Modern therapeutic management and future directions

Lukas, R. V., Gondi, V., Stupp, R. & Raizer, J. J., Jan 1 2018, In : ONCOLOGY (United States). 32, 2, p. e11-e19

Research output: Contribution to journalArticle

Lymphoma
Central Nervous System
Central Nervous System Neoplasms
Therapeutics
Methotrexate
6 Citations (Scopus)

Primary central nervous system lymphoma: Part 1: Epidemiology, diagnosis, staging, and prognosis

Lukas, R. V., Stupp, R., Gondi, V. & Raizer, J. J., Jan 1 2018, In : ONCOLOGY (United States). 32, 1, p. 17-27 11 p.

Research output: Contribution to journalArticle

Lymphoma
Epidemiology
Central Nervous System
Central Nervous System Neoplasms
Central Nervous System Diseases
1 Citation (Scopus)

Response to BRAF/MEK inhibition after progression with BRAF inhibition in a patient with anaplastic pleomorphic xanthoastrocytoma

Hussain, F., Horbinski, C. M., Chmura, S. J., Yamini, B. & Lukas, R. V., Sep 1 2018, In : Neurologist. 23, 5, p. 163-166 4 p.

Research output: Contribution to journalArticle

Mitogen-Activated Protein Kinase Kinases
Central Nervous System Neoplasms
Disease Progression
Mutation
PLX4032
2017
2 Citations (Scopus)

Buzz Juice: Neurological sequelae of synthetic cannabinoids

Kak, M., Mikhail, F., Yano, S. T., Guan, R. & Lukas, R. V., Mar 1 2017, In : Journal of Clinical Neuroscience. 37, p. 43 1 p.

Research output: Contribution to journalArticle

Cannabinoids
Confusion
Corpus Callosum
Hallucinations
Ataxia
1 Citation (Scopus)

CNS hemangioblastomatosis in a patient without von Hippel-Lindau disease

Franco, A., Pytel, P., Lukas, R. V., Chennamaneni, R. & Collins, J. M., Apr 1 2017, In : CNS oncology. 6, 2, p. 101-105 5 p.

Research output: Contribution to journalArticle

Hemangioblastoma
von Hippel-Lindau Disease
Spine
Memory Disorders
Genetic Testing

Impact of treatment variability on survival in immune-competent and immune- compromised patients with primary central nervous system lymphoma

Karmali, R., Nabhan, C., Petrich, A., Raizer, J., Peace, D., Lukas, R., Gordon, L., Basu, S., Chuakkapalli, V. & Venugopal, P., Apr 2017, In : British Journal of Haemotology. 177, 1, p. 72-79 8 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Impact of treatment variability on survival in immuno-competent and immuno-compromised patients with primary central nervous lymphoma

Karmali, R., Nabhan, C., Petrich, A. M., Raizer, J., Peace, D., Lukas, R., Gordon, L. I., Basu, S., Chukkapalli, V. & Venugopal, P., Apr 1 2017, In : British Journal of Haematology. 177, 1, p. 72-79 8 p.

Research output: Contribution to journalArticle

Lymphoma
Survival
Radiotherapy
Methotrexate
Drug Therapy

Perceptions of clinical neurosciences amongst trainees in Wuhan, China.

Lukas, RV., Dong, H., Li, J., Wang, Z., Jiang, I. & Sherer, R., 2017, In : Future Neurology.

Research output: Contribution to journalArticle

Perceptions of clinical neurosciences among trainees in Wuhan, China

Lukas, R. V., Dong, H., Li, J., Wang, Z., Jiang, I. & Sherer, R., May 1 2017, In : Future Neurology. 12, 2, p. 65-70 6 p.

Research output: Contribution to journalArticle

Neurology
Neurosciences
China
Medical Students
Learning
6 Citations (Scopus)
4 Citations (Scopus)

Skin toxicities associated with tumor treating fields: case based review

Lukas, R. V., Ratermann, K. L., Wong, E. T. & Villano, J. L., Dec 1 2017, In : Journal of Neuro-Oncology. 135, 3, p. 593-599 7 p.

Research output: Contribution to journalArticle

temozolomide
Glioblastoma
Skin
Patient Advocacy
Neoplasms

Trends in neurology fellowship training

Williams, JSA., Hodgson, TS., Goldenberg, FD. & Lukas, RV., Apr 18 2017, In : Neuroimmunology and Neuroinflammation. 4, p. 65-68 4 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Views on Careers in Clinical Neurosciences Among Neurosurgeons and Neurologists in China

Lukas, R. V., Ma, C., Chen, J., Dong, H., Li, J., Wang, Z., Jiang, I., Fu, K. M., Satnarayan, S., Albert, D. V. F. & Sherer, R., Feb 1 2017, In : World Neurosurgery. 98, p. 532-537 6 p.

Research output: Contribution to journalArticle

Neurosciences
China
Physicians
Career Choice
Mentors
2016
1 Citation (Scopus)

Advances in brain metastases presented at the American Society of Clinical Oncology 2016 Annual Meeting: Part II

Chen, L. F., Patel, J. D. & Lukas, R. V., Dec 1 2016, In : Future Oncology. 12, 23, p. 2669-2672 4 p.

Research output: Contribution to journalArticle

Interleukin-3
Neoplasm Metastasis
Brain
Radiotherapy
Research Personnel
2 Citations (Scopus)

Advances in brain metastases presented at the American Society of Clinical Oncology 2016 Annual Meeting: PART i

Chen, L. F., Patel, J. D. & Lukas, R. V., Nov 1 2016, In : Future Oncology. 12, 22, p. 2535-2538 4 p.

Research output: Contribution to journalArticle

Interleukin-3
Neoplasm Metastasis
Brain
Epidemiology
Research Personnel
1 Citation (Scopus)

Breadth versus volume: Neurology outpatient clinic cases in medical education

Albert, D. V., Blood, A. D., Park, Y. S., Brorson, J. R. & Lukas, R. V., Jun 1 2016, In : Journal of Clinical Neuroscience. 28, p. 20-23 4 p.

Research output: Contribution to journalArticle

Neurology
Medical Education
Ambulatory Care Facilities
Coroners and Medical Examiners
Students

Central nervous system blastomycosis presenting as a year-long chronic headache

Grebenciucova, E., Lesniak, MS., Pytel, P. & Lukas, RV., 2016, In : Neuroimmunology and Neuroinflammation. 3, p. 17-19 3 p.

Research output: Contribution to journalArticle

How I Manage: Elderly Patients with Glioblastoma

Lukas, RV., Aug 10 2016, In : Clinical Oncology News.

Research output: Contribution to journalArticle

Leptomeningeal carcinomatosis from pancreatic cancer associated with germline BRCA mutations: case reports and review of the literature.

Amico, AL., Lukas, RV. & Kindler, HL., 2016, In : Journal of the Pancreas. 17, 2, p. 241-246 6 p.

Research output: Contribution to journalArticle

Management of Leptomeningeal Disease From Solid Tumors

Lukas, R. V., Buerki, R. & Mrugala, M. M., Aug 1 2016, In : Oncology (Williston Park, N.Y.). 30, 8, p. 724-730 7 p.

Research output: Contribution to journalArticle

Disease Management
Neoplasms

Quiz on High-Grade Gliomas

Lukas, RV., Nov 9 2016, In : Clinical Oncology News.

Research output: Contribution to journalArticle

Serum immune-biomarkers in gliomas

Buerki, RA. & Lukas, RV., 2016, In : Neuroimmunology and Neuroinflammation. 3, p. 198-200 3 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Updates from the Neuro-Oncology section of the 2015 American Neurological Association annual meeting

Lukas, R. V., Wainwright, D. A. & Laterra, J. J., Jan 2016, In : Future Oncology. 12, 2, p. 143-147 5 p.

Research output: Contribution to journalArticle

Immunotherapy
National Institute of Neurological Disorders and Stroke
Neurocutaneous Syndromes
Dioxygenases
Tuberous Sclerosis
10 Citations (Scopus)

Why neurology? Factors which influence career choice in neurology

Albert, D. V., Hoyle, C., Yin, H., McCoyd, M. & Lukas, R. V., 2016, In : Neurological Research. 38, 1, p. 10-14 5 p.

Research output: Contribution to journalArticle

Career Choice
Neurology
Mentors
Medical Students
Chi-Square Distribution
2015

Atypical ganglioneurocytoma: case report and review of the literature

Eliyas, JK., Pytel, P., Lukas, RV. & Gabikian, P., 2015, In : Case Reports in Clinical Pathology. 2, 4, p. 7-13 7 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Leptomeningeal carcinomatosis in esophageal cancer: A case series and systematic review of the literature

Lukas, R. V., Mata-Machado, N. A., Nicholas, M. K., Salgia, R., Antic, T. & Villaflor, V. M., Nov 1 2015, In : Diseases of the Esophagus. 28, 8, p. 772-781 10 p.

Research output: Contribution to journalArticle

Meningeal Carcinomatosis
Esophageal Neoplasms
temozolomide
Topotecan
Survival
6 Citations (Scopus)

Neurology objective structured clinical examination reliability using generalizability theory

Blood, A. D., Park, Y. S., Lukas, R. V. & Brorson, J. R., Nov 3 2015, In : Neurology. 85, 18, p. 1623-1629 7 p.

Research output: Contribution to journalArticle

Neurology
Students
Medical Students
Reproducibility of Results
Medicine
4 Citations (Scopus)

ROS1 rearranged non-small cell lung cancer brain metastases respond to low dose radiotherapy

Lukas, R. V., Hasan, Y., Nicholas, M. K. & Salgia, R., Dec 1 2015, In : Journal of Clinical Neuroscience. 22, 12, p. 1978-1979 2 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Brain Neoplasms
Proto-Oncogene Proteins
Radiotherapy
Neoplasm Metastasis
2 Citations (Scopus)

Society for Neuro-Oncology 2014 annual meeting updates on central nervous system metastases

Lukas, R. V., Mehta, M. P. & Lesniak, M. S., Jun 1 2015, In : Neuro-Oncology Practice. 2, 2, p. 57-61 5 p.

Research output: Contribution to journalArticle

Central Nervous System
Neoplasm Metastasis
Brain
Radiotherapy
Meningeal Carcinomatosis
22 Citations (Scopus)

Structure of neuroscience clerkships in medical schools and matching in neuromedicine

Albert, D. V., Yin, H., Amidei, C., Dixit, K. S., Brorson, J. R. & Lukas, R. V., Jul 1 2015, In : Neurology. 85, 2, p. 172-176 5 p.

Research output: Contribution to journalArticle

Internship and Residency
Neurosciences
Medical Schools
Neurology
Students
19 Citations (Scopus)

The kynurenine to tryptophan ratio as a prognostic tool for glioblastoma patients enrolling in immunotherapy

Zhai, L., Dey, M., Lauing, K. L., Gritsina, G., Kaur, R., Lukas, R. V., Nicholas, M. K., Rademaker, A. W., Dostal, C. R., McCusker, R. H., Raizer, J. J., Parsa, A. T., Bloch, O. & Wainwright, D. A., Dec 2015, In : Journal of Clinical Neuroscience. 22, 12, p. 1964-1968 5 p.

Research output: Contribution to journalArticle

Kynurenine
Glioblastoma
Tryptophan
Immunotherapy
Indoleamine-Pyrrole 2,3,-Dioxygenase
2014

A 16-year-old male with dizziness, parasthesias, and ataxia

Tsien, M. Z., Brorson, J. R., Lukas, R. V. & Dawson, E. C., 2014, In : Pediatric Annals. 43, 5, p. e116-e119

Research output: Contribution to journalArticle

Dizziness
Ataxia
Stroke
Tomography
Brain Stem Infarctions

Advanced neuroimaging studies in a patient with brain metastases from transitional cell carcinoma of the bladder

Choi, J. Y., Gabikian, P., Zhu, F., Appelbaum, D. E., Wollmann, R. & Lukas, R. V., 2014, In : Journal of Neuroimaging. 24, 4, p. 429-431 3 p.

Research output: Contribution to journalArticle

Octreotide
Transitional Cell Carcinoma
Neuroimaging
Urinary Bladder
Neoplasm Metastasis
2 Citations (Scopus)

Assessment of neurological clinical management reasoning in medical students

Lukas, R. V., Blood, A. D., Park, Y. S. & Brorson, J. R., 2014, In : Journal of Clinical Neuroscience. 21, 6, p. 919-922 4 p.

Research output: Contribution to journalArticle

Medical Students
Neurology
Coroners and Medical Examiners
Therapeutics
Long-Term Care
9 Citations (Scopus)

Attitudes toward neurosciences in medical students in Wuhan, China: A survey study

Lukas, R. V., Cooper, B., Morgan, I., Brorson, J. R., Dong, H. & Sherer, R., Sep 1 2014, In : World Neurosurgery. 82, 3, p. 266-269 4 p.

Research output: Contribution to journalArticle

Neurology
Neurosciences
Medical Students
China
Students