• 2142 Citations
1993 …2021
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Personal profile

Research Interests

Dr. Hashizume's primary research interests in understanding of the molecular mechanisms, that affect the aggressive/ invasive biological behavior of pediatric malignant glioma and would accordingly reveal potential therapeutic targets for glioma therapy.

Training Experience

1992Residency, St. Marianna University
1997Residency, St. Marianna University
1999Postdoctoral Fellowship, University of Texas, MD Anderson Cancer Center

Education/Academic qualification

PhD, St. Marianna University

… → 1996

MD, St. Marianna University

… → 1990

Keywords

  • Neuro-Oncology
  • Pediatrics

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  • 18 Similar Profiles
Glioma Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Brain Neoplasms Medicine & Life Sciences
Pediatrics Medicine & Life Sciences
Heterografts Medicine & Life Sciences
Therapeutics Medicine & Life Sciences
Glioblastoma Medicine & Life Sciences
Epigenomics Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Grants 2014 2021

Histones
Histone Code
Epigenomics
Proteins
Modifier Genes
Epigenomics
Histone Code
Histones
Neoplasms
Growth
Histone Demethylases
Brain Stem Neoplasms
Glioma
Brain Stem
Pediatrics

Research Output 1993 2019

ACVR1 R206H cooperates with H3.1K27M in promoting diffuse intrinsic pontine glioma pathogenesis

Hoeman, C. M., Cordero, F. J., Hu, G., Misuraca, K., Romero, M. M., Cardona, H. J., Nazarian, J., Hashizume, R., McLendon, R., Yu, P., Procissi, D., Gadd, S. L. & Becher, O. J., Dec 1 2019, In : Nature communications. 10, 1, 1023.

Research output: Contribution to journalArticle

pathogenesis
Glioma
Tumors
tumors
mutations

Global Reduction of H3K4me3 Improves Chemotherapeutic Efficacy for Pediatric Ependymomas

Lewis, R., Li, Y. D., Hoffman, L., Hashizume, R., Gravohac, G., Rice, G., Wadhwani, N. R., Jie, C., Pundy, T., Mania-Farnell, B., Mayanil, C. S. K., Soares, M. B., Lei, T., James, C. D., Foreman, N. K., Tomita, T. & Xi, G., Jun 1 2019, In : Neoplasia (United States). 21, 6, p. 505-515 11 p.

Research output: Contribution to journalArticle

Open Access
Ependymoma
Pediatrics
Histone Code
Neoplasms
Post Translational Protein Processing

Molecular and translational advances in meningiomas

International Consortium on Meningiomas, Jan 14 2019, In : Neuro-oncology. 21, p. I4-I17

Research output: Contribution to journalArticle

Meningioma
Clinical Trials
Epigenomics
Neoplasms
Therapeutics
1 Citation (Scopus)

CSF H3F3A K27M circulating tumor DNA copy number quantifies tumor growth and in vitro treatment response

Stallard, S., Savelieff, M. G., Wierzbicki, K., Mullan, B., Miklja, Z., Bruzek, A., Garcia, T., Siada, R., Anderson, B., Singer, B. H., Hashizume, R., Carcaboso, A. M., McMurray, K. Q., Heth, J., Muraszko, K., Robertson, P. L., Mody, R., Venneti, S., Garton, H. & Koschmann, C., Aug 15 2018, In : Acta Neuropathologica Communications. 6, 1, 1 p.

Research output: Contribution to journalLetter

DNA
Growth
Neoplasms
In Vitro Techniques

Measuring Tumor Metabolism in Pediatric Diffuse Intrinsic Pontine Glioma Using Hyperpolarized Carbon-13 MR Metabolic Imaging

Autry, A. W., Hashizume, R., James, C. D., Larson, P. E. Z., Vigneron, D. B. & Park, I., Jan 1 2018, In : Contrast Media and Molecular Imaging. 2018, 3215658.

Research output: Contribution to journalArticle

Glioma
Carbon
Lactic Acid
Pediatrics
Pyruvic Acid