Grants per year
Personal profile
Research Interests
Dr. Hashizume's primary research interests in understanding of the molecular mechanisms, that affect the aggressive/ invasive biological behavior of pediatric malignant glioma and would accordingly reveal potential therapeutic targets for glioma therapy.
Training Experience
| 1992 | Residency, St. Marianna University |
| 1997 | Residency, St. Marianna University |
| 1999 | Postdoctoral Fellowship, University of Texas, MD Anderson Cancer Center |
Education/Academic qualification
PhD, St. Marianna University
… → 1996
MD, St. Marianna University
… → 1990
Keywords
- Neuro-Oncology
- Pediatrics
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Glioma
Medicine & Life Sciences
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Pediatrics
Medicine & Life Sciences
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Heterografts
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Therapeutics
Medicine & Life Sciences
Medulloblastoma
Medicine & Life Sciences
Glioblastoma
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Grants 2014 2021
Targeted Inhibition of EZH2 and BET BRD4 for the treatment of AT/RT
7/1/19 → 6/30/20
Project: Research project
Epigenetic Targeted Therapy and Resistance in Pediatric Rhabdoid Tumor
2/1/19 → 1/31/21
Project: Research project
Targeting histone demethylase activity for the treatment of pediatric brainstem glioma
Bi, Y. & Hashizume, R.
National Institute of Neurological Disorders and Stroke
9/15/15 → 6/30/20
Project: Research project
Histone Demethylases
Brain Stem Neoplasms
Glioma
Brain Stem
Pediatrics
Targeted Inhibition of EZH2 and BET BRD4 for the treatment of AT/RT
7/1/18 → 6/30/19
Project: Research project
Histones
Histone Code
Epigenomics
Proteins
Modifier Genes
Targeted Inhibition of EZH2 and BET BRD4 for the treatment of AT/RT
Bear Necessities Pediatric Cancer Foundation
7/1/18 → 6/30/19
Project: Research project
Research Output 1993 2019
3
Citations
(Scopus)
ACVR1 R206H cooperates with H3.1K27M in promoting diffuse intrinsic pontine glioma pathogenesis
Hoeman, C. M., Cordero, F. J., Hu, G., Misuraca, K., Romero, M. M., Cardona, H. J., Nazarian, J., Hashizume, R., McLendon, R., Yu, P., Procissi, D., Gadd, S. L. & Becher, O. J., Dec 1 2019, In : Nature communications. 10, 1, 1023.Research output: Contribution to journal › Article
pathogenesis
Glioma
Tumors
tumors
mutations
Advances in multidisciplinary therapy for meningiomas
International Consortium on Meningiomas, Jan 14 2019, In : Neuro-oncology. 21, p. I18-I31Research output: Contribution to journal › Article
Open Access
Meningioma
trabectedin
Therapeutics
Radiotherapy
Focal Adhesion Protein-Tyrosine Kinases
Global Reduction of H3K4me3 Improves Chemotherapeutic Efficacy for Pediatric Ependymomas
Lewis, R., Li, Y. D., Hoffman, L., Hashizume, R., Gravohac, G., Rice, G., Wadhwani, N. R., Jie, C., Pundy, T., Mania-Farnell, B., Mayanil, C. S. K., Soares, M. B., Lei, T., James, C. D., Foreman, N. K., Tomita, T. & Xi, G., Jun 1 2019, In : Neoplasia (United States). 21, 6, p. 505-515 11 p.Research output: Contribution to journal › Article
Open Access
Ependymoma
Pediatrics
Histone Code
Neoplasms
Post Translational Protein Processing
4
Citations
(Scopus)
Imaging and diagnostic advances for intracranial meningiomas
International Consortium on Meningiomas, Jan 14 2019, In : Neuro-oncology. 21, p. I44-I61Research output: Contribution to journal › Article
Open Access
Meningioma
Diagnostic Imaging
Central Nervous System Neoplasms
Neoplasms
Information Storage and Retrieval
Life after surgical resection of a meningioma: A prospective cross-sectional study evaluating health-related quality of life
International Consortium on Meningiomas, Jan 14 2019, In : Neuro-oncology. 21, p. I32-I43Research output: Contribution to journal › Article
Open Access
Meningioma
Cross-Sectional Studies
Quality of Life
Fatigue
Sleep