• 2707 Citations
1993 …2020

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Targeting Processive Transcription Elongation via SEC Disruption for MYC-Induced Cancer Therapy

Liang, K., Smith, E. R., Aoi, Y., Stoltz, K. L., Katagi, H., Woodfin, A. R., Rendleman, E. J., Marshall, S. A., Murray, D. C., Wang, L., Ozark, P. A., Mishra, R. K., Hashizume, R., Schiltz, G. E. & Shilatifard, A., Oct 18 2018, In : Cell. 175, 3, p. 766-779.e17

Research output: Contribution to journalArticle

21 Scopus citations

Targeting wee1 for the treatment of pediatric high-grade gliomas

Mueller, S., Hashizume, R., Yang, X., Kolkowitz, I., Olow, A. K., Phillips, J., Smirnov, I., Tom, M. W., Prados, M. D., James, C. D., Berger, M. S., Gupta, N. & Haas-Kogan, D. A., Mar 2014, In : Neuro-oncology. 16, 3, p. 352-360 9 p.

Research output: Contribution to journalArticle

52 Scopus citations

Tenascin-C expression contributes to pediatric brainstem glioma tumor phenotype and represents a novel biomarker of disease

Qi, J., Esfahani, D. R., Huang, T., Ozark, P., Bartom, E., Hashizume, R., Bonner, E. R., An, S., Horbinski, C. M., James, C. D. & Saratsis, A. M., May 15 2019, In : Acta Neuropathologica Communications. 7, 1, 75.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

The histone H3.3K27M mutation in pediatric glioma reprograms H3K27 methylation and gene expression

Chan, K. M., Fang, D., Gan, H., Hashizume, R., Yu, C., Schroeder, M., Gupta, N., Mueller, S., David James, C., Jenkins, R., Sarkaria, J. & Zhang, Z., May 1 2013, In : Genes and Development. 27, 9, p. 985-990 6 p.

Research output: Contribution to journalArticle

327 Scopus citations

Therapeutic targeting of polycomb and BET bromodomain proteins in diffuse intrinsic pontine gliomas

Piunti, A., Hashizume, R., Morgan, M. A., Bartom, E. T., Horbinski, C. M., Marshall, S. A., Rendleman, E. J., Ma, Q., Takahashi, Y. H., Woodfin, A. R., Misharin, A. V., Abshiru, N. A., Lulla, R. R., Saratsis, A. M., Kelleher, N. L., James, C. D. & Shilatifard, A., Apr 1 2017, In : Nature Medicine. 23, 4, p. 493-500 8 p.

Research output: Contribution to journalArticle

115 Scopus citations

The RING Heterodimer BRCA1-BARD1 Is a Ubiquitin Ligase Inactivated by a Breast Cancer-derived Mutation

Hashizume, R., Fukuda, M., Maeda, I., Nishikawa, H., Oyake, D., Yabuki, Y., Ogata, H. & Ohta, T., May 4 2001, In : Journal of Biological Chemistry. 276, 18, p. 14537-14540 4 p.

Research output: Contribution to journalArticle

492 Scopus citations

Voltage-gated potassium channel EAG2 controls mitotic entry and tumor growth in medulloblastoma via regulating cell volume dynamics

Huang, X., Dubuc, A. M., Hashizume, R., Berg, J., He, Y., Wang, J., Chiang, C., Cooper, M. K., Northcott, P. A., Taylor, M. D., Barnes, M. J., Tihan, T., Chen, J., Hackett, C. S., Weiss, W. A., David James, C., Rowitch, D. H., Shuman, M. A., Jan, Y. N. & Jan, L. Y., Aug 15 2012, In : Genes and Development. 26, 16, p. 1780-1796 17 p.

Research output: Contribution to journalArticle

43 Scopus citations