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Personal profile

Education/Academic qualification

Biochemistry and Molecular Biology, PhD, Harvard University

… → 1980

Biology, BA, Cornell University

… → 1975

Fingerprint Dive into the research topics where Robert A Holmgren is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 6 Similar Profiles
Drosophila Medicine & Life Sciences
Hedgehogs Medicine & Life Sciences
Genes Medicine & Life Sciences
Zinc Fingers Medicine & Life Sciences
Ribes Medicine & Life Sciences
Transcription Factors Medicine & Life Sciences
Cell Nucleus Active Transport Medicine & Life Sciences
Imaginal Discs Medicine & Life Sciences

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Grants 2000 2021

Research Output 1979 2017

  • 2850 Citations
  • 32 Article
  • 2 Chapter
  • 1 Review article
3 Citations (Scopus)

Dose-dependent transduction of hedgehog relies on phosphorylation-based feedback between the G-protein-coupled receptor smoothened and the kinase fused

Sanial, M., Bécam, I., Hofmann, L., Behague, J., Argüelles, C., Gourhand, V., Bruzzone, L., Holmgren, R. A. & Plessis, A., May 15 2017, In : Development (Cambridge). 144, 10, p. 1841-1850 10 p.

Research output: Contribution to journalArticle

G-Protein-Coupled Receptor Kinases
Hedgehogs
Phosphorylation
Phosphotransferases
Imaginal Discs
4 Citations (Scopus)

Control of the dynamics and homeostasis of the Drosophila Hedgehog receptor Patched by two C2-WW-HECT-E3 Ubiquitin ligases

Brigui, A., Hofmann, L., Argüelles, C., Sanial, M., Holmgren, R. A. & Plessis, A., Oct 7 2015, In : Open Biology. 5, 10, 150112.

Research output: Contribution to journalArticle

Ubiquitin-Protein Ligases
Hedgehogs
Homeostasis
Ligases
Ubiquitin
53 Citations (Scopus)

Chemical map of Schizosaccharomyces pombe reveals species-specific features in nucleosome positioning

Moyle-Heyrman, G., Zaichuk, T., Xi, L., Zhang, Q., Uhlenbeck, O. C., Holmgren, R. A., Widom, J. & Wang, J., Dec 10 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 50, p. 20158-20163 6 p.

Research output: Contribution to journalArticle

Schizosaccharomyces
Nucleosomes
Transcription Initiation Site
Saccharomyces cerevisiae
DNA
31 Citations (Scopus)

Specific inhibition of the transcription factor Ci by a cobalt(III) Schiff base-DNA conjugate

Hurtado, R. R., Harney, A. S., Heffern, M. C., Holbrook, R. J., Holmgren, R. A. & Meade, T. J., Feb 6 2012, In : Molecular Pharmaceutics. 9, 2, p. 325-333 9 p.

Research output: Contribution to journalArticle

Schiff Bases
Cobalt
Hedgehogs
Transcription Factors
DNA
21 Citations (Scopus)

A Three-part signal governs differential processing of Gli1 and Gli3 proteins by the proteasome

Schrader, E. K., Harstad, K. G., Holmgren, R. A. & Matouschek, A., Nov 11 2011, In : Journal of Biological Chemistry. 286, 45, p. 39051-39058 8 p.

Research output: Contribution to journalArticle

Zinc Fingers
Proteasome Endopeptidase Complex
Protein Sorting Signals
Processing
Signal processing