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Research Output 1979 2019

2019

Diabetes alters pH control in rat retina

Dmitriev, A. V., Henderson, D. & Linsenmeier, R. A., Feb 1 2019, In : Investigative Ophthalmology and Visual Science. 60, 2, p. 723-730 8 p.

Research output: Contribution to journalArticle

Open Access
dorzolamide
Retina
Blood Glucose
Carbonic Anhydrases
Glucose

Emixustat reduces metabolic demand of dark activity in the retina

Kubota, R., Calkins, D. J., Henry, S. H. & Linsenmeier, R. A., Jan 1 2019, In : Investigative Ophthalmology and Visual Science. 60, 14, p. 4924-4930 7 p.

Research output: Contribution to journalArticle

Retina
Cations
Oxygen
Oxygen Consumption
Light
2 Citations (Scopus)
Light Coagulation
Optical Coherence Tomography
Diabetic Retinopathy
Angiography
Theoretical Models
1 Citation (Scopus)

The logic of ionic homeostasis: Cations are for voltage, but not for volume

Dmitriev, A. V., Dmitriev, A. A. & Linsenmeier, R. A., Mar 1 2019, In : PLoS computational biology. 15, 3, e1006894.

Research output: Contribution to journalArticle

Open Access
Homeostasis
homeostasis
Cations
cations
Conductance
2018
1 Citation (Scopus)

Brain tissue oxygen regulation in awake and anesthetized neonates

Aksenov, D. P., Dmitriev, A. V., Miller, M. J., Wyrwicz, A. M. & Linsenmeier, R. A., Jun 1 2018, In : Neuropharmacology. 135, p. 368-375 8 p.

Research output: Contribution to journalArticle

Newborn Infant
Oxygen
General Anesthetics
Brain
Anesthesia

IUSE: EHR - Enhancing and expanding experiential learning modules across disciplines and institutions

Kim, G. J., Linsenmeier, R., Reissman, T. & Finch, M. B., Jun 23 2018, In : ASEE Annual Conference and Exposition, Conference Proceedings. 2018-June

Research output: Contribution to journalConference article

Problem-Based Learning
3 Citations (Scopus)

Retinal pH and Acid Regulation During Metabolic Acidosis

Dreffs, A., Henderson, D., Dmitriev, A. V., Antonetti, D. A. & Linsenmeier, R. A., Jul 3 2018, In : Current eye research. 43, 7, p. 902-912 11 p.

Research output: Contribution to journalArticle

Acidosis
Acids
Retina
Chloride-Bicarbonate Antiporters
Carbonic Anhydrase II
2017
1 Citation (Scopus)
Biomedical engineering
Teaching
Students
14 Citations (Scopus)

Increased retinal oxygen metabolism precedes microvascular alterations in type 1 diabetic mice

Liu, W., Wang, S., Soetikno, B., Yi, J., Zhang, K., Chen, S., Linsenmeier, R. A., Sorenson, C. M., Sheibani, N. & Zhang, H. F., Feb 2017, In : Investigative Ophthalmology and Visual Science. 58, 2, p. 981-989 9 p.

Research output: Contribution to journalArticle

Oxygen
Control Groups
Optical Coherence Tomography
Diabetic Retinopathy
Type 1 Diabetes Mellitus
40 Citations (Scopus)

Retinal oxygen: from animals to humans

Linsenmeier, R. A. & Zhang, H. F., May 1 2017, In : Progress in Retinal and Eye Research. 58, p. 115-151 37 p.

Research output: Contribution to journalReview article

Microelectrodes
Hyperoxia
Oximetry
Retinal Detachment
Oxygen
2016
1 Citation (Scopus)

Developing innovative interdisciplinary biomedical engineering programs in Nigeria: Lessons learned

Gatchell, D. W., Linsenmeier, R. A., Murphy, R. L., Coker, A. O. & Osuntoki, A. A., Jan 1 2016, ASEE 2016 International Forum. American Society for Engineering Education

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Biomedical engineering
Nigeria
engineering
grant
training program
7 Citations (Scopus)

Development of diabetes-induced acidosis in the rat retina

Dmitriev, A. V., Henderson, D. & Linsenmeier, R. A., Aug 1 2016, In : Experimental eye research. 149, p. 16-25 10 p.

Research output: Contribution to journalArticle

Acidosis
Retina
Choroid
Ion-Selective Electrodes
Long Evans Rats

In memory of Christina Enroth-Cugell, distinguished vision scientist

Linsenmeier, R. A., Oct 1 2016, In : Experimental eye research. 151, p. 45-46 2 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Light-induced pH changes in the intact retinae of normal and early diabetic rats

Dmitriev, A. V., Henderson, D. & Linsenmeier, R. A., Apr 1 2016, In : Experimental eye research. 145, p. 148-157 10 p.

Research output: Contribution to journalArticle

Retina
Light
Retinal Pigment Epithelium
Microelectrodes
Long Evans Rats
9 Citations (Scopus)

Mentored Discussions of Teaching: An Introductory Teaching Development Program for Future STEM Faculty

Baiduc, R. R., Linsenmeier, R. A. & Ruggeri, N. L., Jun 1 2016, In : Innovative Higher Education. 41, 3, p. 237-254 18 p.

Research output: Contribution to journalArticle

mathematics
engineering
Teaching
science
entry level
3 Citations (Scopus)

Spontaneous fluctuations of PO2 in the rabbit somatosensory cortex

Linsenmeier, R. A., Aksenov, D. P., Faber, H. M., Makar, P. & Wyrwicz, A. M., Jan 1 2016, Oxygen Transport to Tissue XXXVII. Springer New York LLC, p. 311-317 7 p. (Advances in Experimental Medicine and Biology; vol. 876).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Somatosensory Cortex
Isoflurane
Hyperoxia
Tissue
Rabbits
2015
56 Citations (Scopus)

Association of diabetic macular nonperfusion with outer retinal disruption on optical coherence tomography

Scarinci, F., Jampol, L. M., Linsenmeier, R. A. & Fawzi, A. A., Sep 1 2015, In : JAMA ophthalmology. 133, 9, p. 1036-1044 9 p.

Research output: Contribution to journalArticle

Optical Coherence Tomography
Macular Edema
Diabetic Retinopathy
Ischemia
Fluorescein Angiography

Introduction

Linsenmeier, R., Jan 1 2015, In : Current Eye Research. 40, 2, 1 p.

Research output: Contribution to journalEditorial

Introduction

Linsenmeier, R., Feb 1 2015, In : Current eye research. 40, 2, 1 p.

Research output: Contribution to journalEditorial

Ocular Physiological Phenomena
Sex Factors
Eye Diseases
21 Citations (Scopus)

Retinal oxygen extraction in humans

Werkmeister, R. M., Schmidl, D., Aschinger, G., Doblhoff-Dier, V., Palkovits, S., Wirth, M., Garhöfer, G., Linsenmeier, R. A., Leitgeb, R. A. & Schmetterer, L., Oct 27 2015, In : Scientific reports. 5, 15763.

Research output: Contribution to journalArticle

Oxygen
Respiration
Retina
Retinal Diseases
Spectrophotometry
13 Citations (Scopus)
angiogenesis
rodents
angiography
retina
tomography
69 Citations (Scopus)

Visible light optical coherence tomography measures retinal oxygen metabolic response to systemic oxygenation

Yi, J., Liu, W., Chen, S., Backman, V., Sheibani, N., Sorenson, C. M., Fawzi, A. A., Linsenmeier, R. A. & Zhang, H. F., Sep 25 2015, In : Light: Science and Applications. 4, 9, e334.

Research output: Contribution to journalArticle

Oxygenation
oxygenation
Optical tomography
tomography
Oxygen
2014
69 Citations (Scopus)

A combined method to quantify the retinal metabolic rate of oxygen using photoacoustic ophthalmoscopy and optical coherence tomography

Song, W., Wei, Q., Liu, W., Liu, T., Yi, J., Sheibani, N., Fawzi, A. A., Linsenmeier, R. A., Jiao, S. & Zhang, H. F., 2014, In : Scientific reports. 4, 6525.

Research output: Contribution to journalArticle

Ophthalmoscopy
Optical Coherence Tomography
Oxygen
Diabetic Retinopathy
Ophthalmology
11 Citations (Scopus)

Increased intraretinal PO2in short-term diabetic rats

Lau, J. C. M. & Linsenmeier, R. A., Dec 1 2014, In : Diabetes. 63, 12, p. 4338-4342 5 p.

Research output: Contribution to journalArticle

Retina
Oxygen Consumption
Oxygen
Ocular Adaptation
Dark Adaptation
3 Citations (Scopus)
Biomedical engineering
Curricula
Mechanics
Statistics
Educational technology

Some cognitive issues in engineering design

Linsenmeier, R. A., Cole, J. Y. & Glucksberg, M. R., 2014, Integrating Cognitive Science with Innovative Teaching in STEM Disciplines. McDaniel, M. A., Frey, R. F., Fitzpatrick, S. M. & Roediger, H. L. (eds.). eBook ed. St. Louis, MO: Washington University Libraries

Research output: Chapter in Book/Report/Conference proceedingChapter

2013
21 Citations (Scopus)

Diabetes changes expression of genes related to glutamate neurotransmission and transport in the Long-Evans rat retina

Lau, J. C. M., Kroes, R. A., Moskal, J. R. & Linsenmeier, R. A., Jul 19 2013, In : Molecular vision. 19, p. 1538-1553 16 p.

Research output: Contribution to journalArticle

Long Evans Rats
Synaptic Transmission
Vascular Endothelial Growth Factor A
Amino Acid Transport System X-AG
Retina
11 Citations (Scopus)

Medical and biological engineering in the next 20 years: The promise and the challenges

Linsenmeier, R. A., Jul 17 2013, In : IEEE Transactions on Biomedical Engineering. 60, 7, p. 1767-1775 9 p., 6519290.

Research output: Contribution to journalArticle

Health
Food supply
Engineers
Health care
Water supply

Retinal bioengineering

Linsenmeier, R. A. & Troy, J. B., Jan 1 2013, Neural Engineering: Second Edition. Springer US, p. 565-634 70 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Neurology
Brain
Microelectrodes
Weighing
Neurons
2012
24 Citations (Scopus)

24-h core temperature in obese and lean men and women

Hoffmann, M. E., Rodriguez, S. M., Zeiss, D. M., Wachsberg, K. N., Kushner, R. F., Landsberg, L. & Linsenmeier, R. A., Aug 1 2012, In : Obesity. 20, 8, p. 1585-1590 6 p.

Research output: Contribution to journalArticle

Temperature
Sleep
Exercise
Obesity
Follicular Phase
6 Citations (Scopus)

Effect of isoflurane on brain tissue oxygen tension and cerebral autoregulation in rabbits

Aksenov, D., Eassa, J. E., Lakhoo, J., Wyrwicz, A. & Linsenmeier, R. A., Aug 30 2012, In : Neuroscience Letters. 524, 2, p. 116-118 3 p.

Research output: Contribution to journalArticle

Isoflurane
Homeostasis
Oxygen
Rabbits
Brain
39 Citations (Scopus)

Oxygen consumption and distribution in the Long-Evans rat retina

Lau, J. C. M. & Linsenmeier, R. A., Sep 1 2012, In : Experimental eye research. 102, p. 50-58 9 p.

Research output: Contribution to journalArticle

Long Evans Rats
Oxygen Consumption
Retina
Cats
Ocular Adaptation
3 Citations (Scopus)

Oxygen Measurements in Animals

Linsenmeier, R. A., 2012, Occular Blood Flow. Schmetterer, L. & Kiel, J. (eds.). 2012 ed. Springer, p. 65-94

Research output: Chapter in Book/Report/Conference proceedingChapter

Using instruction to improve mathematical modeling in capstone design

Cole, J., Linsenmeier, R. A., Miller, T. & Glucksberg, M. R., Jan 1 2012, 119th ASEE Annual Conference and Exposition. American Society for Engineering Education

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Students
Mathematical models
Decision making
2011
7 Citations (Scopus)
Students
Mathematical models
Decision making
24 Citations (Scopus)

Decreased circulation in the feline choriocapillaris underlying retinal photocoagulation lesions

Lee, C. J., Smith, J. H., Kang-Mieler, J. J., Budzynski, E. & Linsenmeier, R. A., May 1 2011, In : Investigative Ophthalmology and Visual Science. 52, 6, p. 3398-3403 6 p.

Research output: Contribution to journalArticle

Light Coagulation
Felidae
Retina
Indocyanine Green
Microspheres
7 Citations (Scopus)

Exploring senior engineering students' conceptions of modeling

Carberry, A. R., McKenna, A. F., Linsenmeier, R. A. & Cole, J., Jan 1 2011, In : ASEE Annual Conference and Exposition, Conference Proceedings.

Research output: Contribution to journalArticle

Students
Mathematical models

Student reactions to electronic learning modules in BME

Linsenmeier, R. A., McElrath, M. A., Murray, W. & Haugh-Scheidt, L. M., Jan 1 2011, In : ASEE Annual Conference and Exposition, Conference Proceedings.

Research output: Contribution to journalArticle

Students
Biomechanics
Physiology
Information systems
Feedback
2010
4 Citations (Scopus)
Students
Mathematical models
Knowledge engineering
Experiments
15 Citations (Scopus)

Metabolic responses to light in monkey photoreceptors

Wang, S., Birol, G., Budzynski, E., Flynn, R. & Linsenmeier, R. A., Jun 1 2010, In : Current eye research. 35, 6, p. 510-518 9 p.

Research output: Contribution to journalArticle

Lighting
Haplorhini
Light
Choroid
Darkness
1 Citation (Scopus)

Retinal Energy Metabolism: Mechanisms and Management

Linsenmeier, R. A., 2010, Ocular Disease: Mechanisms and Management. Oxford, UK: Saunders/Elsevier, p. 572-578

Research output: Chapter in Book/Report/Conference proceedingChapter

2009
13 Citations (Scopus)
Body Temperature
Basal Metabolism
Temperature
Thermogenesis
Obesity
17 Citations (Scopus)

Gene expression patterns in hypoxic and post-hypoxic adult rat retina with special reference to the NMDA receptor and its interactome.

Crosson, L. A., Kroes, R. A., Moskal, J. R. & Linsenmeier, R. A., Mar 9 2009, In : Molecular Vision. 15, p. 296-311 16 p.

Research output: Contribution to journalArticle

N-Methyl-D-Aspartate Receptors
Retina
Gene Expression
Genes
Hypoxia
38 Citations (Scopus)
Body Temperature
Obesity
Temperature
Sloths
Body Temperature Changes
2008

A unique research experience in bioengineering education for undergraduates in the VaNTH REU

Linsenmeier, R., Alley, J., Hirsch, P., Klein, S., Greenberg, J. & Bourgeois, M., Jan 1 2008, In : ASEE Annual Conference and Exposition, Conference Proceedings.

Research output: Contribution to journalConference article

Education
Students
Engineering education
Bioengineering
Innovation
9 Citations (Scopus)

Characterizing computational adaptive expertise

McKenna, A., Linsenmeier, R. A. & Glucksberg, M. R., Jan 1 2008, In : ASEE Annual Conference and Exposition, Conference Proceedings.

Research output: Contribution to journalConference article

Education
Students
Biomedical engineering
Curricula
Innovation

Consommation et diffusion de l'oxygène rétinien

Linsenmeier, R. A., 2008, Pathologies vasculaires oculaires. Paris: Masson, p. 99-107

Research output: Chapter in Book/Report/Conference proceedingChapter

37 Citations (Scopus)

Effects of photocoagulation on intraretinal PO2 in cat

Budzynski, E., Smith, J. H., Bryar, P., Birol, G. & Linsenmeier, R. A., Jan 1 2008, In : Investigative Ophthalmology and Visual Science. 49, 1, p. 380-389 10 p.

Research output: Contribution to journalArticle

Light Coagulation
Retina
Cats
Respiration
Air
19 Citations (Scopus)

Evaluation of a challenge-based human metabolism laboratory for undergraduates

Linsenmeier, R. A., Kanter, D. E., Smith, H. D., Linsenmeier, K. A. & Mckenna, A. F., Jan 1 2008, In : Journal of Engineering Education. 97, 2, p. 213-222 10 p.

Research output: Contribution to journalArticle

Metabolism
Students
evaluation
student
experience
3 Citations (Scopus)
Biomedical engineering
Physiology
Students
Curricula
Engineers