If you made any changes in Pure, your changes will be visible here soon.

Research Output 1979 2019

Filter
Article
2019

Diabetes alters pH control in rat retina

Dmitriev, A. V., Henderson, D. & Linsenmeier, R. A., Feb 1 2019, In : Investigative Ophthalmology and Visual Science. 60, 2, p. 723-730 8 p.

Research output: Contribution to journalArticle

Open Access
dorzolamide
Retina
Blood Glucose
Carbonic Anhydrases
Glucose

Emixustat reduces metabolic demand of dark activity in the retina

Kubota, R., Calkins, D. J., Henry, S. H. & Linsenmeier, R. A., Jan 1 2019, In : Investigative Ophthalmology and Visual Science. 60, 14, p. 4924-4930 7 p.

Research output: Contribution to journalArticle

Open Access
Retina
Cations
Oxygen
Oxygen Consumption
Light
2 Citations (Scopus)
Light Coagulation
Optical Coherence Tomography
Diabetic Retinopathy
Angiography
Theoretical Models
1 Citation (Scopus)

The logic of ionic homeostasis: Cations are for voltage, but not for volume

Dmitriev, A. V., Dmitriev, A. A. & Linsenmeier, R. A., Mar 1 2019, In : PLoS computational biology. 15, 3, e1006894.

Research output: Contribution to journalArticle

Open Access
Homeostasis
homeostasis
Cations
cations
Conductance
2018
1 Citation (Scopus)

Brain tissue oxygen regulation in awake and anesthetized neonates

Aksenov, D. P., Dmitriev, A. V., Miller, M. J., Wyrwicz, A. M. & Linsenmeier, R. A., Jun 1 2018, In : Neuropharmacology. 135, p. 368-375 8 p.

Research output: Contribution to journalArticle

Newborn Infant
Oxygen
General Anesthetics
Brain
Anesthesia
3 Citations (Scopus)

Retinal pH and Acid Regulation During Metabolic Acidosis

Dreffs, A., Henderson, D., Dmitriev, A. V., Antonetti, D. A. & Linsenmeier, R. A., Jul 3 2018, In : Current eye research. 43, 7, p. 902-912 11 p.

Research output: Contribution to journalArticle

Acidosis
Acids
Retina
Chloride-Bicarbonate Antiporters
Carbonic Anhydrase II
2017
14 Citations (Scopus)

Increased retinal oxygen metabolism precedes microvascular alterations in type 1 diabetic mice

Liu, W., Wang, S., Soetikno, B., Yi, J., Zhang, K., Chen, S., Linsenmeier, R. A., Sorenson, C. M., Sheibani, N. & Zhang, H. F., Feb 2017, In : Investigative Ophthalmology and Visual Science. 58, 2, p. 981-989 9 p.

Research output: Contribution to journalArticle

Oxygen
Control Groups
Optical Coherence Tomography
Diabetic Retinopathy
Type 1 Diabetes Mellitus
2016
7 Citations (Scopus)

Development of diabetes-induced acidosis in the rat retina

Dmitriev, A. V., Henderson, D. & Linsenmeier, R. A., Aug 1 2016, In : Experimental eye research. 149, p. 16-25 10 p.

Research output: Contribution to journalArticle

Acidosis
Retina
Choroid
Ion-Selective Electrodes
Long Evans Rats

In memory of Christina Enroth-Cugell, distinguished vision scientist

Linsenmeier, R. A., Oct 1 2016, In : Experimental eye research. 151, p. 45-46 2 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Light-induced pH changes in the intact retinae of normal and early diabetic rats

Dmitriev, A. V., Henderson, D. & Linsenmeier, R. A., Apr 1 2016, In : Experimental eye research. 145, p. 148-157 10 p.

Research output: Contribution to journalArticle

Retina
Light
Retinal Pigment Epithelium
Microelectrodes
Long Evans Rats
9 Citations (Scopus)

Mentored Discussions of Teaching: An Introductory Teaching Development Program for Future STEM Faculty

Baiduc, R. R., Linsenmeier, R. A. & Ruggeri, N. L., Jun 1 2016, In : Innovative Higher Education. 41, 3, p. 237-254 18 p.

Research output: Contribution to journalArticle

mathematics
engineering
Teaching
science
entry level
2015
56 Citations (Scopus)

Association of diabetic macular nonperfusion with outer retinal disruption on optical coherence tomography

Scarinci, F., Jampol, L. M., Linsenmeier, R. A. & Fawzi, A. A., Sep 1 2015, In : JAMA ophthalmology. 133, 9, p. 1036-1044 9 p.

Research output: Contribution to journalArticle

Optical Coherence Tomography
Macular Edema
Diabetic Retinopathy
Ischemia
Fluorescein Angiography
20 Citations (Scopus)

Retinal oxygen extraction in humans

Werkmeister, R. M., Schmidl, D., Aschinger, G., Doblhoff-Dier, V., Palkovits, S., Wirth, M., Garhöfer, G., Linsenmeier, R. A., Leitgeb, R. A. & Schmetterer, L., Oct 27 2015, In : Scientific reports. 5, 15763.

Research output: Contribution to journalArticle

Oxygen
Respiration
Retina
Retinal Diseases
Spectrophotometry
13 Citations (Scopus)
angiogenesis
rodents
angiography
retina
tomography
68 Citations (Scopus)

Visible light optical coherence tomography measures retinal oxygen metabolic response to systemic oxygenation

Yi, J., Liu, W., Chen, S., Backman, V., Sheibani, N., Sorenson, C. M., Fawzi, A. A., Linsenmeier, R. A. & Zhang, H. F., Sep 25 2015, In : Light: Science and Applications. 4, 9, e334.

Research output: Contribution to journalArticle

Oxygenation
oxygenation
Optical tomography
tomography
Oxygen
2014
69 Citations (Scopus)

A combined method to quantify the retinal metabolic rate of oxygen using photoacoustic ophthalmoscopy and optical coherence tomography

Song, W., Wei, Q., Liu, W., Liu, T., Yi, J., Sheibani, N., Fawzi, A. A., Linsenmeier, R. A., Jiao, S. & Zhang, H. F., 2014, In : Scientific reports. 4, 6525.

Research output: Contribution to journalArticle

Ophthalmoscopy
Optical Coherence Tomography
Oxygen
Diabetic Retinopathy
Ophthalmology
11 Citations (Scopus)

Increased intraretinal PO2in short-term diabetic rats

Lau, J. C. M. & Linsenmeier, R. A., Dec 1 2014, In : Diabetes. 63, 12, p. 4338-4342 5 p.

Research output: Contribution to journalArticle

Retina
Oxygen Consumption
Oxygen
Ocular Adaptation
Dark Adaptation
2013
21 Citations (Scopus)

Diabetes changes expression of genes related to glutamate neurotransmission and transport in the Long-Evans rat retina

Lau, J. C. M., Kroes, R. A., Moskal, J. R. & Linsenmeier, R. A., Jul 19 2013, In : Molecular vision. 19, p. 1538-1553 16 p.

Research output: Contribution to journalArticle

Long Evans Rats
Synaptic Transmission
Vascular Endothelial Growth Factor A
Amino Acid Transport System X-AG
Retina
11 Citations (Scopus)

Medical and biological engineering in the next 20 years: The promise and the challenges

Linsenmeier, R. A., Jul 17 2013, In : IEEE Transactions on Biomedical Engineering. 60, 7, p. 1767-1775 9 p., 6519290.

Research output: Contribution to journalArticle

Health
Food supply
Engineers
Health care
Water supply
2012
24 Citations (Scopus)

24-h core temperature in obese and lean men and women

Hoffmann, M. E., Rodriguez, S. M., Zeiss, D. M., Wachsberg, K. N., Kushner, R. F., Landsberg, L. & Linsenmeier, R. A., Aug 1 2012, In : Obesity. 20, 8, p. 1585-1590 6 p.

Research output: Contribution to journalArticle

Temperature
Sleep
Exercise
Obesity
Follicular Phase
6 Citations (Scopus)

Effect of isoflurane on brain tissue oxygen tension and cerebral autoregulation in rabbits

Aksenov, D., Eassa, J. E., Lakhoo, J., Wyrwicz, A. & Linsenmeier, R. A., Aug 30 2012, In : Neuroscience Letters. 524, 2, p. 116-118 3 p.

Research output: Contribution to journalArticle

Isoflurane
Homeostasis
Oxygen
Rabbits
Brain
39 Citations (Scopus)

Oxygen consumption and distribution in the Long-Evans rat retina

Lau, J. C. M. & Linsenmeier, R. A., Sep 1 2012, In : Experimental eye research. 102, p. 50-58 9 p.

Research output: Contribution to journalArticle

Long Evans Rats
Oxygen Consumption
Retina
Cats
Ocular Adaptation
2011
7 Citations (Scopus)
Students
Mathematical models
Decision making
23 Citations (Scopus)

Decreased circulation in the feline choriocapillaris underlying retinal photocoagulation lesions

Lee, C. J., Smith, J. H., Kang-Mieler, J. J., Budzynski, E. & Linsenmeier, R. A., May 1 2011, In : Investigative Ophthalmology and Visual Science. 52, 6, p. 3398-3403 6 p.

Research output: Contribution to journalArticle

Light Coagulation
Felidae
Retina
Indocyanine Green
Microspheres
7 Citations (Scopus)

Exploring senior engineering students' conceptions of modeling

Carberry, A. R., McKenna, A. F., Linsenmeier, R. A. & Cole, J., Jan 1 2011, In : ASEE Annual Conference and Exposition, Conference Proceedings.

Research output: Contribution to journalArticle

Students
Mathematical models

Student reactions to electronic learning modules in BME

Linsenmeier, R. A., McElrath, M. A., Murray, W. & Haugh-Scheidt, L. M., Jan 1 2011, In : ASEE Annual Conference and Exposition, Conference Proceedings.

Research output: Contribution to journalArticle

Students
Biomechanics
Physiology
Information systems
Feedback
2010
15 Citations (Scopus)

Metabolic responses to light in monkey photoreceptors

Wang, S., Birol, G., Budzynski, E., Flynn, R. & Linsenmeier, R. A., Jun 1 2010, In : Current eye research. 35, 6, p. 510-518 9 p.

Research output: Contribution to journalArticle

Lighting
Haplorhini
Light
Choroid
Darkness
2009
17 Citations (Scopus)

Gene expression patterns in hypoxic and post-hypoxic adult rat retina with special reference to the NMDA receptor and its interactome.

Crosson, L. A., Kroes, R. A., Moskal, J. R. & Linsenmeier, R. A., Mar 9 2009, In : Molecular Vision. 15, p. 296-311 16 p.

Research output: Contribution to journalArticle

N-Methyl-D-Aspartate Receptors
Retina
Gene Expression
Genes
Hypoxia
38 Citations (Scopus)
Body Temperature
Obesity
Temperature
Sloths
Body Temperature Changes
2008
37 Citations (Scopus)

Effects of photocoagulation on intraretinal PO2 in cat

Budzynski, E., Smith, J. H., Bryar, P., Birol, G. & Linsenmeier, R. A., Jan 1 2008, In : Investigative Ophthalmology and Visual Science. 49, 1, p. 380-389 10 p.

Research output: Contribution to journalArticle

Light Coagulation
Retina
Cats
Respiration
Air
19 Citations (Scopus)

Evaluation of a challenge-based human metabolism laboratory for undergraduates

Linsenmeier, R. A., Kanter, D. E., Smith, H. D., Linsenmeier, K. A. & Mckenna, A. F., Jan 1 2008, In : Journal of Engineering Education. 97, 2, p. 213-222 10 p.

Research output: Contribution to journalArticle

Metabolism
Students
evaluation
student
experience
2007
10 Citations (Scopus)

Effect of carbogen (95% O2/5% CO2) on retinal oxygenation in dark-adapted anesthetized cats

Chung, C. K. & Linsenmeier, R. A., Jul 1 2007, In : Current eye research. 32, 7-8, p. 699-707 9 p.

Research output: Contribution to journalArticle

Retina
Cats
Oxygen
Gases
Oxygen Consumption
25 Citations (Scopus)

Hyperoxia improves oxygen consumption in the detached feline retina

Wang, S. & Linsenmeier, R. A., Mar 1 2007, In : Investigative Ophthalmology and Visual Science. 48, 3, p. 1335-1341 7 p.

Research output: Contribution to journalArticle

Hyperoxia
Felidae
Oxygen Consumption
Retina
Oxygen
124 Citations (Scopus)

Oxygen distribution and consumption in the macaque retina

Birol, G., Wang, S., Budzynski, E., Wangsa-Wirawan, N. D. & Linsenmeier, R. A., Sep 1 2007, In : American Journal of Physiology - Heart and Circulatory Physiology. 293, 3

Research output: Contribution to journalArticle

Macaca
Oxygen Consumption
Retina
Dark Adaptation
Cats
2006
apprenticeship
Teaching
student
instruction
science
60 Citations (Scopus)

Retinal oxygenation and oxygen metabolism in abyssinian cats with a hereditary retinal degeneration

Padnick-Silver, L., Kang Derwent, J. J., Giuliano, E., Narfström, K. & Linsenmeier, R. A., Aug 1 2006, In : Investigative Ophthalmology and Visual Science. 47, 8, p. 3683-3689 7 p.

Research output: Contribution to journalArticle

Retinal Degeneration
Cats
Oxygen
Retinitis Pigmentosa
Retinal Vessels
21 Citations (Scopus)

The electroretinogram components in Abyssinian cats with hereditary retinal degeneration

Kang Derwent, J. J., Padnick-Silver, L., McRipley, M., Giuliano, E., Linsenmeier, R. A. & Narfström, K., Aug 1 2006, In : Investigative Ophthalmology and Visual Science. 47, 8, p. 3673-3682 10 p.

Research output: Contribution to journalArticle

Retinal Degeneration
Cats
Eragrostis
Light Signal Transduction
Microscopy
2005
29 Citations (Scopus)

Effect of hypoxemia and hyperglycemia on pH in the intact cat retina

Padnick-Silver, L. & Linsenmeier, R. A., Dec 1 2005, In : Archives of ophthalmology. 123, 12, p. 1684-1690 7 p.

Research output: Contribution to journalArticle

Hyperglycemia
Retina
Cats
Glucose
Retinal Diseases
23 Citations (Scopus)

Intraretinal pH in diabetic cats

Budzynski, E., Wangsa-Wirawan, N. D., Padnick-Silver, L., Hatchell, D. L. & Linsenmeier, R. A., Mar 1 2005, In : Current eye research. 30, 3, p. 229-240 12 p.

Research output: Contribution to journalArticle

Retina
Cats
Choroid
Normal Distribution
Microelectrodes
18 Citations (Scopus)

Retinal arterial occlusion leads to acidosis in the cat

Birol, G., Budzynski, E., Wangsa-Wirawan, N. D. & Linsenmeier, R. A., Jan 1 2005, In : Experimental Eye Research. 80, 4, p. 527-533 7 p.

Research output: Contribution to journalArticle

Acidosis
Retina
Cats
Ventilation
Retinal Artery Occlusion
2004
10 Citations (Scopus)

Hyperoxia promotes electroretinogram recovery after retinal artery occlusion in cats

Birol, G., Budzynski, E., Wangsa-Wirawan, N. D. & Linsenmeier, R. A., Oct 1 2004, In : Investigative Ophthalmology and Visual Science. 45, 10, p. 3690-3696 7 p.

Research output: Contribution to journalArticle

Retinal Artery Occlusion
Hyperoxia
Cats
Air
Respiration
2003
22 Citations (Scopus)

Effect of acute hyperglycemia on oxygen and oxidative metabolism in the intact cat retina

Padnick-Silver, L. & Linsenmeier, R. A., Feb 1 2003, In : Investigative Ophthalmology and Visual Science. 44, 2, p. 745-750 6 p.

Research output: Contribution to journalArticle

Hyperglycemia
Retina
Cats
Oxygen
Oxygen Consumption
2002
162 Citations (Scopus)

Photoreceptor inner segments in monkey and human retina: Mitochondrial density, optics, and regional variation

Hoang, Q. V., Linsenmeier, R. A., Chung, C. K. & Curcio, C. A., Jul 1 2002, In : Visual Neuroscience. 19, 4, p. 395-407 13 p.

Research output: Contribution to journalArticle

Haplorhini
Retina
Mitochondria
Vertebrate Photoreceptor Cells
Macaca
27 Citations (Scopus)

Quantification of in vivo anaerobic metabolism in the normal cat retina through intraretinal pH measurements

Padnick-Silver, L. & Linsenmeier, R. A., Nov 1 2002, In : Visual Neuroscience. 19, 6, p. 793-806 14 p.

Research output: Contribution to journalArticle

Anaerobiosis
Retina
Cats
Ocular Adaptation
Lactic Acid

The role of the pH microenvironment in retinal diseases

Linsenmeier, R. A., Budzynski, E. & Chung, C. K., Dec 1 2002, In : Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. 3, p. 2133-2134 2 p.

Research output: Contribution to journalArticle

Retinal Diseases
Microelectrodes
Medical problems
Blood
Retina
2001
11 Citations (Scopus)

Hypoglycemia increases the sensitivity of the cat electroretinogram to hypoxemia

Kang Derwent, J. J. & Linsenmeier, R. A., Dec 1 2001, In : Visual Neuroscience. 18, 6, p. 983-993 11 p.

Research output: Contribution to journalArticle

Hypoglycemia
Cats
Glycolysis
Hypoglycemic Agents
Blood Glucose
21 Citations (Scopus)

Intraretinal analysis of the a-wave of the electroretinogram (ERG) in dark-adapted intact cat retina

Kang Derwent, J. J. & Linsenmeier, R. A., Aug 22 2001, In : Visual Neuroscience. 18, 3, p. 353-363 11 p.

Research output: Contribution to journalArticle

Microelectrodes
Retina
Cats
Kynurenic Acid
Electrodes
34 Citations (Scopus)

Measurement of blood flow through the retinal circulation of the cat during normoxia and hypoxemia using fluorescent microspheres

Ahmed, J., Pulfer, M. K. & Linsenmeier, R. A., Jan 1 2001, In : Microvascular Research. 62, 2, p. 143-153 11 p.

Research output: Contribution to journalArticle

Microspheres
Cats
Blood
Retina
Flow measurement
2000
42 Citations (Scopus)

Effects of hypoxemia on the a- and b-waves of the electroretinogram in the cat retina

Derwent, J. K. & Linsenmeier, R. A., Jan 1 2000, In : Investigative Ophthalmology and Visual Science. 41, 11, p. 3634-3642 9 p.

Research output: Contribution to journalArticle

Retina
Cats
Electrodes
Hypoxia
Vitreous Body
235 Citations (Scopus)

Metabolic dependence of photoreceptors on the choroid in the normal and detached retina

Linsenmeier, R. A. & Padnick-Silver, L., Sep 25 2000, In : Investigative Ophthalmology and Visual Science. 41, 10, p. 3117-3123 7 p.

Research output: Contribution to journalArticle

Choroid
Hyperoxia
Retina
Oxygen
Microelectrodes