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2019

Diabetes alters pH control in rat retina

Dmitriev, A. V., Henderson, D. & Linsenmeier, R. A., Feb 1 2019, In : Investigative Ophthalmology and Visual Science. 60, 2, p. 723-730 8 p.

Research output: Contribution to journalArticle

Open Access

Emixustat reduces metabolic demand of dark activity in the retina

Kubota, R., Calkins, D. J., Henry, S. H. & Linsenmeier, R. A., Jan 1 2019, In : Investigative Ophthalmology and Visual Science. 60, 14, p. 4924-4930 7 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations
3 Scopus citations

The logic of ionic homeostasis: Cations are for voltage, but not for volume

Dmitriev, A. V., Dmitriev, A. A. & Linsenmeier, R. A., Mar 1 2019, In : PLoS computational biology. 15, 3, e1006894.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
2018

Brain tissue oxygen regulation in awake and anesthetized neonates

Aksenov, D. P., Dmitriev, A. V., Miller, M. J., Wyrwicz, A. M. & Linsenmeier, R. A., Jun 2018, In : Neuropharmacology. 135, p. 368-375 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Retinal pH and Acid Regulation During Metabolic Acidosis

Dreffs, A., Henderson, D., Dmitriev, A. V., Antonetti, D. A. & Linsenmeier, R. A., Jul 3 2018, In : Current eye research. 43, 7, p. 902-912 11 p.

Research output: Contribution to journalArticle

3 Scopus citations
2017

Increased retinal oxygen metabolism precedes microvascular alterations in type 1 diabetic mice

Liu, W., Wang, S., Soetikno, B., Yi, J., Zhang, K., Chen, S., Linsenmeier, R. A., Sorenson, C. M., Sheibani, N. & Zhang, H. F., Feb 2017, In : Investigative Ophthalmology and Visual Science. 58, 2, p. 981-989 9 p.

Research output: Contribution to journalArticle

14 Scopus citations
2016

Development of diabetes-induced acidosis in the rat retina

Dmitriev, A. V., Henderson, D. & Linsenmeier, R. A., Aug 1 2016, In : Experimental eye research. 149, p. 16-25 10 p.

Research output: Contribution to journalArticle

7 Scopus citations

In memory of Christina Enroth-Cugell, distinguished vision scientist

Linsenmeier, R. A., Oct 1 2016, In : Experimental eye research. 151, p. 45-46 2 p.

Research output: Contribution to journalArticle

Light-induced pH changes in the intact retinae of normal and early diabetic rats

Dmitriev, A. V., Henderson, D. & Linsenmeier, R. A., Apr 1 2016, In : Experimental eye research. 145, p. 148-157 10 p.

Research output: Contribution to journalArticle

2 Scopus citations

Mentored Discussions of Teaching: An Introductory Teaching Development Program for Future STEM Faculty

Baiduc, R. R., Linsenmeier, R. A. & Ruggeri, N. L., Jun 1 2016, In : Innovative Higher Education. 41, 3, p. 237-254 18 p.

Research output: Contribution to journalArticle

9 Scopus citations
2015

Association of diabetic macular nonperfusion with outer retinal disruption on optical coherence tomography

Scarinci, F., Jampol, L. M., Linsenmeier, R. A. & Fawzi, A. A., Sep 1 2015, In : JAMA ophthalmology. 133, 9, p. 1036-1044 9 p.

Research output: Contribution to journalArticle

57 Scopus citations

Retinal oxygen extraction in humans

Werkmeister, R. M., Schmidl, D., Aschinger, G., Doblhoff-Dier, V., Palkovits, S., Wirth, M., Garhöfer, G., Linsenmeier, R. A., Leitgeb, R. A. & Schmetterer, L., Oct 27 2015, In : Scientific reports. 5, 15763.

Research output: Contribution to journalArticle

22 Scopus citations
13 Scopus citations

Visible light optical coherence tomography measures retinal oxygen metabolic response to systemic oxygenation

Yi, J., Liu, W., Chen, S., Backman, V., Sheibani, N., Sorenson, C. M., Fawzi, A. A., Linsenmeier, R. A. & Zhang, H. F., Sep 25 2015, In : Light: Science and Applications. 4, 9, e334.

Research output: Contribution to journalArticle

73 Scopus citations
2014

A combined method to quantify the retinal metabolic rate of oxygen using photoacoustic ophthalmoscopy and optical coherence tomography

Song, W., Wei, Q., Liu, W., Liu, T., Yi, J., Sheibani, N., Fawzi, A. A., Linsenmeier, R. A., Jiao, S. & Zhang, H. F., 2014, In : Scientific reports. 4, 6525.

Research output: Contribution to journalArticle

70 Scopus citations

Increased intraretinal PO2in short-term diabetic rats

Lau, J. C. M. & Linsenmeier, R. A., Dec 1 2014, In : Diabetes. 63, 12, p. 4338-4342 5 p.

Research output: Contribution to journalArticle

11 Scopus citations
2013

Diabetes changes expression of genes related to glutamate neurotransmission and transport in the Long-Evans rat retina

Lau, J. C. M., Kroes, R. A., Moskal, J. R. & Linsenmeier, R. A., Jul 19 2013, In : Molecular vision. 19, p. 1538-1553 16 p.

Research output: Contribution to journalArticle

22 Scopus citations

Medical and biological engineering in the next 20 years: The promise and the challenges

Linsenmeier, R. A., Jul 17 2013, In : IEEE Transactions on Biomedical Engineering. 60, 7, p. 1767-1775 9 p., 6519290.

Research output: Contribution to journalArticle

11 Scopus citations
2012

24-h core temperature in obese and lean men and women

Hoffmann, M. E., Rodriguez, S. M., Zeiss, D. M., Wachsberg, K. N., Kushner, R. F., Landsberg, L. & Linsenmeier, R. A., Aug 1 2012, In : Obesity. 20, 8, p. 1585-1590 6 p.

Research output: Contribution to journalArticle

24 Scopus citations

Effect of isoflurane on brain tissue oxygen tension and cerebral autoregulation in rabbits

Aksenov, D., Eassa, J. E., Lakhoo, J., Wyrwicz, A. & Linsenmeier, R. A., Aug 30 2012, In : Neuroscience Letters. 524, 2, p. 116-118 3 p.

Research output: Contribution to journalArticle

6 Scopus citations

Oxygen consumption and distribution in the Long-Evans rat retina

Lau, J. C. M. & Linsenmeier, R. A., Sep 1 2012, In : Experimental eye research. 102, p. 50-58 9 p.

Research output: Contribution to journalArticle

39 Scopus citations
2011
7 Scopus citations

Decreased circulation in the feline choriocapillaris underlying retinal photocoagulation lesions

Lee, C. J., Smith, J. H., Kang-Mieler, J. J., Budzynski, E. & Linsenmeier, R. A., May 1 2011, In : Investigative Ophthalmology and Visual Science. 52, 6, p. 3398-3403 6 p.

Research output: Contribution to journalArticle

24 Scopus citations

Exploring senior engineering students' conceptions of modeling

Carberry, A. R., McKenna, A. F., Linsenmeier, R. A. & Cole, J., Jan 1 2011, In : ASEE Annual Conference and Exposition, Conference Proceedings.

Research output: Contribution to journalArticle

7 Scopus citations

Student reactions to electronic learning modules in BME

Linsenmeier, R. A., McElrath, M. A., Murray, W. & Haugh-Scheidt, L. M., Jan 1 2011, In : ASEE Annual Conference and Exposition, Conference Proceedings.

Research output: Contribution to journalArticle

2010

Metabolic responses to light in monkey photoreceptors

Wang, S., Birol, G., Budzynski, E., Flynn, R. & Linsenmeier, R. A., Jun 1 2010, In : Current eye research. 35, 6, p. 510-518 9 p.

Research output: Contribution to journalArticle

15 Scopus citations
2009

Gene expression patterns in hypoxic and post-hypoxic adult rat retina with special reference to the NMDA receptor and its interactome.

Crosson, L. A., Kroes, R. A., Moskal, J. R. & Linsenmeier, R. A., Mar 9 2009, In : Molecular Vision. 15, p. 296-311 16 p.

Research output: Contribution to journalArticle

17 Scopus citations
39 Scopus citations
2008

Effects of photocoagulation on intraretinal PO2 in cat

Budzynski, E., Smith, J. H., Bryar, P., Birol, G. & Linsenmeier, R. A., Jan 1 2008, In : Investigative Ophthalmology and Visual Science. 49, 1, p. 380-389 10 p.

Research output: Contribution to journalArticle

39 Scopus citations

Evaluation of a challenge-based human metabolism laboratory for undergraduates

Linsenmeier, R. A., Kanter, D. E., Smith, H. D., Linsenmeier, K. A. & Mckenna, A. F., Jan 1 2008, In : Journal of Engineering Education. 97, 2, p. 213-222 10 p.

Research output: Contribution to journalArticle

19 Scopus citations
2007

Effect of carbogen (95% O2/5% CO2) on retinal oxygenation in dark-adapted anesthetized cats

Chung, C. K. & Linsenmeier, R. A., Jul 1 2007, In : Current eye research. 32, 7-8, p. 699-707 9 p.

Research output: Contribution to journalArticle

10 Scopus citations

Hyperoxia improves oxygen consumption in the detached feline retina

Wang, S. & Linsenmeier, R. A., Mar 1 2007, In : Investigative Ophthalmology and Visual Science. 48, 3, p. 1335-1341 7 p.

Research output: Contribution to journalArticle

25 Scopus citations

Oxygen distribution and consumption in the macaque retina

Birol, G., Wang, S., Budzynski, E., Wangsa-Wirawan, N. D. & Linsenmeier, R. A., Sep 1 2007, In : American Journal of Physiology - Heart and Circulatory Physiology. 293, 3

Research output: Contribution to journalArticle

126 Scopus citations
2006

Retinal oxygenation and oxygen metabolism in abyssinian cats with a hereditary retinal degeneration

Padnick-Silver, L., Kang Derwent, J. J., Giuliano, E., Narfström, K. & Linsenmeier, R. A., Aug 1 2006, In : Investigative Ophthalmology and Visual Science. 47, 8, p. 3683-3689 7 p.

Research output: Contribution to journalArticle

60 Scopus citations

The electroretinogram components in Abyssinian cats with hereditary retinal degeneration

Kang Derwent, J. J., Padnick-Silver, L., McRipley, M., Giuliano, E., Linsenmeier, R. A. & Narfström, K., Aug 1 2006, In : Investigative Ophthalmology and Visual Science. 47, 8, p. 3673-3682 10 p.

Research output: Contribution to journalArticle

21 Scopus citations
2005

Effect of hypoxemia and hyperglycemia on pH in the intact cat retina

Padnick-Silver, L. & Linsenmeier, R. A., Dec 1 2005, In : Archives of ophthalmology. 123, 12, p. 1684-1690 7 p.

Research output: Contribution to journalArticle

29 Scopus citations

Intraretinal pH in diabetic cats

Budzynski, E., Wangsa-Wirawan, N. D., Padnick-Silver, L., Hatchell, D. L. & Linsenmeier, R. A., Mar 1 2005, In : Current eye research. 30, 3, p. 229-240 12 p.

Research output: Contribution to journalArticle

23 Scopus citations

Retinal arterial occlusion leads to acidosis in the cat

Birol, G., Budzynski, E., Wangsa-Wirawan, N. D. & Linsenmeier, R. A., Jan 1 2005, In : Experimental Eye Research. 80, 4, p. 527-533 7 p.

Research output: Contribution to journalArticle

18 Scopus citations
2004

Hyperoxia promotes electroretinogram recovery after retinal artery occlusion in cats

Birol, G., Budzynski, E., Wangsa-Wirawan, N. D. & Linsenmeier, R. A., Oct 1 2004, In : Investigative Ophthalmology and Visual Science. 45, 10, p. 3690-3696 7 p.

Research output: Contribution to journalArticle

10 Scopus citations
2003

Effect of acute hyperglycemia on oxygen and oxidative metabolism in the intact cat retina

Padnick-Silver, L. & Linsenmeier, R. A., Feb 1 2003, In : Investigative Ophthalmology and Visual Science. 44, 2, p. 745-750 6 p.

Research output: Contribution to journalArticle

22 Scopus citations
2002

Photoreceptor inner segments in monkey and human retina: Mitochondrial density, optics, and regional variation

Hoang, Q. V., Linsenmeier, R. A., Chung, C. K. & Curcio, C. A., Jul 1 2002, In : Visual Neuroscience. 19, 4, p. 395-407 13 p.

Research output: Contribution to journalArticle

165 Scopus citations

Quantification of in vivo anaerobic metabolism in the normal cat retina through intraretinal pH measurements

Padnick-Silver, L. & Linsenmeier, R. A., Nov 1 2002, In : Visual Neuroscience. 19, 6, p. 793-806 14 p.

Research output: Contribution to journalArticle

27 Scopus citations

The role of the pH microenvironment in retinal diseases

Linsenmeier, R. A., Budzynski, E. & Chung, C. K., Dec 1 2002, In : Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. 3, p. 2133-2134 2 p.

Research output: Contribution to journalArticle

2001

Hypoglycemia increases the sensitivity of the cat electroretinogram to hypoxemia

Kang Derwent, J. J. & Linsenmeier, R. A., Dec 1 2001, In : Visual Neuroscience. 18, 6, p. 983-993 11 p.

Research output: Contribution to journalArticle

11 Scopus citations

Intraretinal analysis of the a-wave of the electroretinogram (ERG) in dark-adapted intact cat retina

Kang Derwent, J. J. & Linsenmeier, R. A., Aug 22 2001, In : Visual Neuroscience. 18, 3, p. 353-363 11 p.

Research output: Contribution to journalArticle

22 Scopus citations

Measurement of blood flow through the retinal circulation of the cat during normoxia and hypoxemia using fluorescent microspheres

Ahmed, J., Pulfer, M. K. & Linsenmeier, R. A., Jan 1 2001, In : Microvascular Research. 62, 2, p. 143-153 11 p.

Research output: Contribution to journalArticle

34 Scopus citations
2000

Effects of hypoxemia on the a- and b-waves of the electroretinogram in the cat retina

Derwent, J. K. & Linsenmeier, R. A., Jan 1 2000, In : Investigative Ophthalmology and Visual Science. 41, 11, p. 3634-3642 9 p.

Research output: Contribution to journalArticle

43 Scopus citations

Metabolic dependence of photoreceptors on the choroid in the normal and detached retina

Linsenmeier, R. A. & Padnick-Silver, L., Sep 25 2000, In : Investigative Ophthalmology and Visual Science. 41, 10, p. 3117-3123 7 p.

Research output: Contribution to journalArticle

235 Scopus citations