Personal profile

Research Interests

Structure, function and dynamic properties of intermediate filaments in essential cell biological phenomena. Regulation of neurite outgrowth, nerve cell shape development and maintenance, growth cone activity and plasticity, and axoplasmic transport. Interactions of intermediate filaments with microtubules and microfilaments, and their associated molecular motors such as kinesin.

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  • 14 Similar Profiles
Intermediate Filaments Medicine & Life Sciences
Lamins Medicine & Life Sciences
Vimentin Medicine & Life Sciences
Proteins Medicine & Life Sciences
Intermediate Filament Proteins Medicine & Life Sciences
Actin Cytoskeleton Medicine & Life Sciences
Microtubules Medicine & Life Sciences
Lamin Type A Medicine & Life Sciences

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Research Output 1969 2017

10 Citations

Chromatin and lamin a determine two different mechanical response regimes of the cell nucleus

Stephens, A. D., Banigan, E. J., Adam, S. A., Goldman, R. D. & Marko, J. F. Jul 7 2017 In : Molecular Biology of the Cell. 28, 14, p. 1984-1996 13 p.

Research output: Research - peer-reviewArticle

Lamin Type A
Cell Nucleus

Giant axonal neuropathy alters the structure of keratin intermediate filaments in human hair

Soomro, A., Alsop, R. J., Negishi, A., Kreplak, L., Fudge, D., Kuczmarski, E. R., Goldman, R. D. & Rheinstädter, M. C. Apr 1 2017 In : Journal of the Royal Society Interface. 14, 129, 20170123

Research output: Research - peer-reviewArticle

Giant Axonal Neuropathy
Intermediate Filaments
13 Citations

The molecular architecture of lamins in somatic cells

Turgay, Y., Eibauer, M., Goldman, A. E., Shimi, T., Khayat, M., Ben-Harush, K., Dubrovsky-Gaupp, A., Sapra, K. T., Goldman, R. D. & Medalia, O. Mar 9 2017 In : Nature. 543, 7644, p. 261-264 4 p.

Research output: Research - peer-reviewArticle

Nuclear Lamina
Lamin Type B
Electron Microscope Tomography
7 Citations

Abnormal intermediate filament organization alters mitochondrial motility in giant axonal neuropathy fibroblasts

Lowery, J., Jain, N., Kuczmarski, E. R., Mahammad, S., Goldman, A., Gelfand, V. I., Opal, P. & Goldman, R. D. Feb 15 2016 In : Molecular Biology of the Cell. 27, 4, p. 608-616 9 p.

Research output: Research - peer-reviewArticle

Giant Axonal Neuropathy
Intermediate Filaments
Intermediate Filament Proteins
Ubiquitin-Protein Ligases
1 Citations

Analyses of the dynamic properties of nuclear lamins by fluorescence recovery after photobleaching (FRAP) and fluorescence correlation spectroscopy (FCS)

Takeshi, S., Pack, C. G. & Goldman, R. D. Jan 1 2016 Methods in Molecular Biology. Humana Press Inc., Vol. 1411, p. 99-111 13 p. (Methods in Molecular Biology; vol. 1411)

Research output: ResearchChapter

Fluorescence Recovery After Photobleaching
Fluorescence Spectrometry
Cell Nucleus
Lamin Type B