Personal profile

Research Interests

Structure, function and dynamic properties of intermediate filaments in essential cell biological phenomena. Regulation of neurite outgrowth, nerve cell shape development and maintenance, growth cone activity and plasticity, and axoplasmic transport. Interactions of intermediate filaments with microtubules and microfilaments, and their associated molecular motors such as kinesin.

Education / Academic qualification

PhD, Princeton University

… → 1967

Fingerprint Fingerprint is based on mining the text of the persons scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 13 Similar Profiles
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Research Output 1969 2018

1 Citations

Chromatin histone modifications and rigidity affect nuclear morphology independent of lamins

Stephens, A. D., Liu, P. Z., Banigan, E. J., Almassalha, L. M., Backman, V., Adam, S. A., Goldman, R. D. & Marko, J. F. Jan 15 2018 In : Molecular Biology of the Cell. 29, 2, p. 220-233 14 p.

Research output: Contribution to journalArticle

Histone Code
Lamins
Blister
Chromatin
Heterochromatin
18 Citations

Chromatin and lamin a determine two different mechanical response regimes of the cell nucleus

Stephens, A. D., Banigan, E. J., Adam, S. A., Goldman, R. D. & Marko, J. F. Jul 7 2017 In : Molecular Biology of the Cell. 28, 14, p. 1984-1996 13 p.

Research output: Contribution to journalArticle

Lamins
Lamin Type A
Cell Nucleus
Chromatin
Mechanics

Giant axonal neuropathy alters the structure of keratin intermediate filaments in human hair

Soomro, A., Alsop, R. J., Negishi, A., Kreplak, L., Fudge, D., Kuczmarski, E. R., Goldman, R. D. & Rheinstädter, M. C. Apr 1 2017 In : Journal of the Royal Society Interface. 14, 129, 20170123

Research output: Contribution to journalArticle

Giant Axonal Neuropathy
Keratin
Intermediate Filaments
Keratins
Hair
27 Citations

The molecular architecture of lamins in somatic cells

Turgay, Y., Eibauer, M., Goldman, A. E., Shimi, T., Khayat, M., Ben-Harush, K., Dubrovsky-Gaupp, A., Sapra, K. T., Goldman, R. D. & Medalia, O. Mar 9 2017 In : Nature. 543, 7644, p. 261-264 4 p.

Research output: Contribution to journalArticle

Lamins
Nuclear Lamina
Chromatin
Lamin Type B
Electron Microscope Tomography
9 Citations

Abnormal intermediate filament organization alters mitochondrial motility in giant axonal neuropathy fibroblasts

Lowery, J., Jain, N., Kuczmarski, E. R., Mahammad, S., Goldman, A., Gelfand, V. I., Opal, P. & Goldman, R. D. Feb 15 2016 In : Molecular Biology of the Cell. 27, 4, p. 608-616 9 p.

Research output: Contribution to journalArticle

Giant Axonal Neuropathy
Intermediate Filaments
Fibroblasts
Intermediate Filament Proteins
Ubiquitin-Protein Ligases