Grants per year
Personal profile
Research Interests
We study the structure, function and dynamic properties of intermediate filaments in essential mammalian cell biological phenomena. Our work focuses on the role of cytoskeletal intermediate filaments in regulating cell shape, mechanics, signal transduction, adhesion, cell motility and molecular cross talk with microtubules and microfilaments. We are also determining the roles of the nuclear lamins in regulating nuclear architecture and chromatin organization.
Education/Academic qualification
PhD, Princeton University
… → 1967
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Grants
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Understanding pathophysiological mechanisms underlying neurodegeneration
Goldman, R., Opal, P. & Savas, J. N.
National Institute of Neurological Disorders and Stroke
7/1/19 → 6/30/21
Project: Research project
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Goldman Admin Subproject for Institution # SP0044258
National Institute of General Medical Sciences
9/1/18 → 7/31/22
Project: Research project
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Project 2 - Role of Intermediate Filaments in Acute Lung Injury
Goldman, R., Ridge, K. M., Ridge, K. M., Shumaker, D. K. & Stehlik, C.
National Heart, Lung, and Blood Institute
9/1/15 → 6/30/21
Project: Research project
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Pathophysiology of Acute Lung Injury
Budinger, G. S., Chandel, N., Dada, L., Goldman, R., Horvath, C. M., Lecuona, E., Perlman, H. R., Ridge, K. M., Stehlik, C., Sznajder, J. I. & Wunderink, R. G.
National Heart, Lung, and Blood Institute
9/1/15 → 6/30/21
Project: Research project
Research Output
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An APEX2 proximity ligation method for mapping interactions with the nuclear lamina
Tran, J. R., Paulson, D. I., Moresco, J. J., Adam, S. A., Yates, J. R., Goldman, R. D. & Zheng, Y., Jan 4 2021, In: The Journal of cell biology. 220, 1Research output: Contribution to journal › Article › peer-review
Open Access -
Effect of Divalent Cations on the Structure and Mechanics of Vimentin Intermediate Filaments
Wu, H., Shen, Y., Wang, D., Herrmann, H., Goldman, R. D. & Weitz, D. A., Jul 7 2020, In: Biophysical Journal. 119, 1, p. 55-64 10 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Mechanical and Non-Mechanical Functions of Filamentous and Non-Filamentous Vimentin
Patteson, A. E., Vahabikashi, A., Goldman, R. D. & Janmey, P. A., Nov 1 2020, In: BioEssays. 42, 11, 2000078.Research output: Contribution to journal › Review article › peer-review
Open Access1 Scopus citations -
NETosis proceeds by cytoskeleton and endomembrane disassembly and PAD4-mediated chromatin decondensation and nuclear envelope rupture
Thiama, H. R., Wong, S. L., Qiu, R., Kittisopikul, M., Vahabikashi, A., Goldman, A. E., Goldman, R. D., Wagner, D. D. & Waterman, C. M., Mar 31 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 13, p. 7326-7337 12 p.Research output: Contribution to journal › Article › peer-review
Open Access15 Scopus citations -
The disassembly of the actin cytoskeleton is an early event during NETosis
Thiam, H. R., Wong, S. L., Qiu, R., Kittisopikul, M., Vahabikashi, A., Goldman, A. E., Goldman, R. D., Wagner, D. D. & Waterman, C. M., Sep 15 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 37, p. 22655-22656 2 p.Research output: Contribution to journal › Letter › peer-review
Open Access