Grants per year
Personal profile
Research Interests
We study the structure, function and dynamic properties of intermediate filaments in essential mammalian cell biological phenomena. Our work focuses on the role of cytoskeletal intermediate filaments in regulating cell shape, mechanics, signal transduction, adhesion, cell motility and molecular cross talk with microtubules and microfilaments. We are also determining the roles of the nuclear lamins in regulating nuclear architecture and chromatin organization.
Education/Academic qualification
PhD, Princeton University
… → 1967
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Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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The Role of Vimentin Cytoskeleton in the Mechanobiology of Schlemm's Canal Endothelium.
6/1/21 → 5/31/23
Project: Research project
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Mechanobiology of Vimentin Intermediate Filaments in 3D Collective Cell Migration
Massachusetts Institute of Technology, National Institute of General Medical Sciences
12/1/20 → 11/30/25
Project: Research project
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Center for 3D Structure and Physics of the Genome
University of Massachusetts Medical School, National Human Genome Research Institute
9/18/20 → 6/30/25
Project: Research project
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Goldman Admin Subproject for Institution # SP0044258
National Institute of General Medical Sciences
9/1/18 → 7/31/22
Project: Research project
Research Output
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An APEX2 proximity ligation method for mapping interactions with the nuclear lamina
Tran, J. R., Paulson, D. I., Moresco, J. J., Adam, S. A., Yates, J. R., Goldman, R. D. & Zheng, Y., Jan 4 2021, In: The Journal of cell biology. 220, 1Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Computational analyses reveal spatial relationships between nuclear pore complexes and specific lamins
Kittisopikul, M., Shimi, T., Tatli, M., Tran, J. R., Zheng, Y., Medalia, O., Jaqaman, K., Adam, S. A. & Goldman, R. D., Feb 2021, In: Journal of Cell Biology. 220, 4, e202007082.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Adaptive multiorientation resolution analysis of complex filamentous network images
Kittisopikul, M., Vahabikashi, A., Shimi, T., Goldman, R. D. & Jaqaman, K., Oct 15 2020, In: Bioinformatics. 36, 20, p. 5093-5103 11 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Effect of Divalent Cations on the Structure and Mechanics of Vimentin Intermediate Filaments
Wu, H., Shen, Y., Wang, D., Herrmann, H., Goldman, R. D. & Weitz, D. A., Jul 7 2020, In: Biophysical Journal. 119, 1, p. 55-64 10 p.Research output: Contribution to journal › Article › peer-review
8 Scopus citations -
Mechanical and Non-Mechanical Functions of Filamentous and Non-Filamentous Vimentin
Patteson, A. E., Vahabikashi, A., Goldman, R. D. & Janmey, P. A., Nov 1 2020, In: BioEssays. 42, 11, 2000078.Research output: Contribution to journal › Review article › peer-review
Open Access6 Scopus citations