Personal profile

Research Interests

Structure, function and dynamic properties of intermediate filaments in essential cell biological phenomena. Regulation of neurite outgrowth, nerve cell shape development and maintenance, growth cone activity and plasticity, and axoplasmic transport. Interactions of intermediate filaments with microtubules and microfilaments, and their associated molecular motors such as kinesin.

Fingerprint Fingerprint is based on mining the text of the persons scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

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Research Output 1969 2017

4 Citations

Chromatin and lamin a determine two different mechanical response regimes of the cell nucleus

Stephens, A. D., Banigan, E. J., Adam, S. A., Goldman, R. D. & Marko, J. F. Jul 7 2017 In : Molecular Biology of the Cell. 28, 14, p. 1984-1996 13 p.

Research output: Contribution to journalArticle

Lamins
Lamin Type A
Cell Nucleus
Chromatin
Progeria

Giant axonal neuropathy alters the structure of keratin intermediate filaments in human hair

Soomro, A., Alsop, R. J., Negishi, A., Kreplak, L., Fudge, D., Kuczmarski, E. R., Goldman, R. D. & Rheinstädter, M. C. Apr 1 2017 In : Journal of the Royal Society Interface. 14, 129, 20170123

Research output: Contribution to journalArticle

Giant Axonal Neuropathy
Intermediate Filaments
Keratins
Hair
Keratin
3 Citations

The molecular architecture of lamins in somatic cells

Turgay, Y., Eibauer, M., Goldman, A. E., Shimi, T., Khayat, M., Ben-Harush, K., Dubrovsky-Gaupp, A., Sapra, K. T., Goldman, R. D. & Medalia, O. Mar 9 2017 In : Nature. 543, 7644, p. 261-264 4 p.

Research output: Contribution to journalArticle

Lamins
Nuclear Lamina
Chromatin
Lamin Type B
Electron Microscope Tomography
5 Citations

Abnormal intermediate filament organization alters mitochondrial motility in giant axonal neuropathy fibroblasts

Lowery, J., Jain, N., Kuczmarski, E. R., Mahammad, S., Goldman, A., Gelfand, V. I., Opal, P. & Goldman, R. D. Feb 15 2016 In : Molecular Biology of the Cell. 27, 4, p. 608-616 9 p.

Research output: Contribution to journalArticle

Giant Axonal Neuropathy
Intermediate Filaments
Fibroblasts
Intermediate Filament Proteins
Ubiquitin-Protein Ligases
1 Citations

Analyses of the dynamic properties of nuclear lamins by fluorescence recovery after photobleaching (FRAP) and fluorescence correlation spectroscopy (FCS)

Takeshi, S., Pack, C. G. & Goldman, R. D. 2016 Methods in Molecular Biology. Humana Press Inc., Vol. 1411, p. 99-111 13 p. (Methods in Molecular Biology; vol. 1411)

Research output: Chapter in Book/Report/Conference proceedingChapter

Lamins
Fluorescence Recovery After Photobleaching
Fluorescence Spectrometry
Cell Nucleus
Lamin Type B