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Personal profile

Research Interests

Research in my lab focuses on two topics: 1) activity-dependent development of circuits in the central nervous system and 2) healthful compensatory responses of cells and organisms to stressful conditions. We use genetically manipulated mice, primary neuron tissue culture and C.elegans in our studies; our approach is cell and molecular biology. Lab Website: http://kalbneuron.com

Training Experience

1983Internship, Montefiore Medical Center
1984Residency, Montefiore Medical Center
1987Residency, Yale-New Haven Hospital
1990Postdoctoral Fellowship, Yale University

Education/Academic qualification

MD, Cornell University Medical College

… → 1982

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Grants

  • Research Output

    Homeostatic regulation of STING protein at the resting state by stabilizer TOLLIP

    Pokatayev, V., Yang, K., Tu, X., Dobbs, N., Wu, J., Kalb, R. G. & Yan, N., Feb 1 2020, In : Nature Immunology. 21, 2, p. 158-167 10 p.

    Research output: Contribution to journalArticle

  • L3MBTL1 regulates ALS/FTD-associated proteotoxicity and quality control

    Lu, J., Periz, G., Lu, Y. N., Tang, Q., Liu, Y., Zhang, T., Shah, Y., Thombre, R., Aljumaah, R., Li, W., Mojsilovic-Petrovic, J., Ji, Y., Johnson, K., Kalb, R. G. & Wang, J., Jan 1 2019, In : Nature Neuroscience.

    Research output: Contribution to journalArticle

  • 1 Scopus citations

    Neuropeptide signaling regulates the susceptibility of developing C. elegans to anoxia

    Doshi, S., Price, E., Landis, J., Barot, U., Sabatella, M., Lans, H. & Kalb, R. G., Feb 1 2019, In : Free Radical Biology and Medicine. 131, p. 197-208 12 p.

    Research output: Contribution to journalArticle

  • 1 Scopus citations

    PTEN self-regulates through USP11 via the PI3K-FOXO pathway to stabilize tumor suppression

    Park, M. K., Yao, Y., Xia, W., Setijono, S. R., Kim, J. H., Vila, I. K., Chiu, H. H., Wu, Y., Billalabeitia, E. G., Lee, M. G., Kalb, R. G., Hung, M. C., Pandolfi, P. P., Song, S. J. & Song, M. S., Dec 1 2019, In : Nature communications. 10, 1, 636.

    Research output: Contribution to journalArticle

    Open Access
  • 8 Scopus citations

    Publisher Correction: L3MBTL1 regulates ALS/FTD-associated proteotoxicity and quality control (Nature Neuroscience, (2019), 22, 6, (875-886), 10.1038/s41593-019-0384-5)

    Lu, J., Periz, G., Lu, Y. N., Tang, Q., Liu, Y., Zhang, T., Shah, Y., Thombre, R., Aljumaah, R., Li, W., Mojsilovic-Petrovic, J., Ji, Y., Johnson, K., Kalb, R. G. & Wang, J., Jul 1 2019, In : Nature Neuroscience. 22, 7, 1 p.

    Research output: Contribution to journalComment/debate

    Open Access