Grants per year
Personal profile
Research Interests
Research in my lab focuses on two topics: 1) activity-dependent development of circuits in the central nervous system and 2) healthful compensatory responses of cells and organisms to stressful conditions. We use genetically manipulated mice, primary neuron tissue culture and C.elegans in our studies; our approach is cell and molecular biology. Lab Website: http://kalbneuron.com
Training Experience
1983 | Internship, Montefiore Medical Center |
1984 | Residency, Montefiore Medical Center |
1987 | Residency, Yale-New Haven Hospital |
1990 | Postdoctoral Fellowship, Yale University |
Education/Academic qualification
MD, Medicine, Cornell University Medical College
… → 1982
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Collaborations and top research areas from the last five years
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Orbitrap Eclipse Mass Spectrometer for Northwestern University Neuroproteomic Collaboration Hub
Savas, J. N., Caraveo Piso, G., Contractor, A., Disterhoft, J. F., Duncan, F. E., Foltz, D. R., Goel, R., Kafader, J. O., Kalb, R. G., Kelleher, N. L., Kiskinis, E., Krainc, D., Mendillo, M. L., Menichella, D. M., Penzes, P., Smith, G. A., Surmeier Jr, D. J., Vassar, R. J., Walsh, D. & Zelano, C.
Office of the Director, National Institutes of Health
3/1/23 → 2/29/24
Project: Research project
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Medical Scientist Training Program
Ardehali, H., Brown, M. A. & Kalb, R. G.
National Institute of General Medical Sciences
7/1/22 → 6/30/27
Project: Research project
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Predoctoral and Postdoctoral Training Program in Aging and Dementia
Vassar, R. J., Weintraub, S., Allada, R., Bevan, M. D., Caraveo Piso, G., Carvill, G. L., Chan, S., Contractor, A., Disterhoft, J. F., Dombeck, D. A., Dong, H., Ferreira, A. B., Flanagan, M. E., Gefen, T. D., Geula, C., Gratton, C., He, C., Kahnt, T., Kalb, R. G., Kennedy, A., Kessler, J., Kiskinis, E., Klein, W. L., Kozorovitskiy, Y., Krainc, D., Li, L., Mazzulli, J., Mesulam, M., Miller, R. J., Morimoto, R. I., Opal, P., Ozdinler, H., Paller, K., Parisiadou, L., Penzes, P., Pinto, L., Prakriya, M., Reber, P. J., Roberts, A. L., Rogalski, E., Savas, J. N., Surmeier Jr, D. J., Swanson, G. T., Voss, J. L., Zee, P. C. & Zelano, C.
5/1/22 → 4/30/27
Project: Research project
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RAD23 Control of ALS phenotypes
National Institute of Neurological Disorders and Stroke
6/1/21 → 5/31/26
Project: Research project
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Erratum: A yeast functional screen predicts new candidate ALS disease genes (Proc. Natl. Acad. Sci. U.S.A. (2011) 108 (20881–20890) DOI: 10.1073/pnas.1109434108)
Couthouis, J., Hart, M. P., Shorter, J., DeJesus-Hernandez, M., Erion, R., Oristano, R., Liu, A. X., Ramos, D., Jethava, N., Hosangadi, D., Epstein, J., Chiang, A., Diaz, Z., Nakaya, T., Ibrahim, F., Kim, H. J., Solski, J. A., Williams, K. L., Mojsilovic-Petrovic, J., Ingre, C., & 21 others , Jan 3 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 1, e2220845120.Research output: Contribution to journal › Comment/debate › peer-review
Open Access -
Enhanced Degradation of Mutant C9ORF72-Derived Toxic Dipeptide Repeat Proteins by 20S Proteasome Activation Results in Restoration of Proteostasis and Neuroprotection
Vanecek, A. S., Mojsilovic-Petrovic, J., Kalb, R. G. & Tepe, J. J., 2022, (Accepted/In press) In: ACS Chemical Neuroscience.Research output: Contribution to journal › Article › peer-review
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Neurons undergo pathogenic metabolic reprogramming in models of familial ALS
Riechers, S. P., Mojsilovic-Petrovic, J., Belton, T. B., Chakrabarty, R. P., Garjani, M., Medvedeva, V., Dalton, C., Wong, Y. C., Chandel, N. S., Dienel, G. & Kalb, R. G., Jun 2022, In: Molecular Metabolism. 60, 101468.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Preconditioning of Caenorhabditis elegans to anoxic insult by inactivation of cholinergic, GABAergic and muscle activity
Bennett, H. L., McClanahan, P. D., Fang-Yen, C. & Kalb, R. G., Apr 2021, In: Genes, Brain and Behavior. 20, 4, e12713.Research output: Contribution to journal › Article › peer-review
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The nuclear ubiquitin ligase adaptor SPOP is a conserved regulator of C9orf72 dipeptide toxicity
Snoznik, C., Medvedeva, V., Mojsilovic-Petrovic, J., Rudich, P., Oosten, J., Kalb, R. G. & Lamitina, T., Oct 5 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 40, e2104664118.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations