Grants per year
Personal profile
Research Interests
I am the Director of the Comprehensive Sickle Cell Program at Ann & Robert H. Lurie Children's Hospital of Chicago. My clinical interests center on hemoglobin disorders, including pediatric and adult sickle cell disease and thalassemia. I am also a clinical investigator with active research programs in these areas. My major research interests focus on exercise responses, inflammation and vascular function as well as their impact on cardiopulmonary fitness, clinical outcomes and physical functioning in children and young adults with sickle cell anemia. I am also the principal investigator of several other protocols at Lurie Children's Hospital that are aligned with my interests in exercise physiology, free-living physical activity, habitual exercise patterns and aerobic training in this population. Other areas of clinical and research focus include patient-reported outcomes, quality of life, transition to adult care, patient-centered medical homes, health disparities and parental decision making regarding research participation in sickle cell disease and thalassemia.
Cardiopulmonary fitness, exercise responses, aerobic training, free-living physical activity, exercise prescription, inflammation, and endothelial function in children and young adults with sickle cell disease. Also career development of trainees (medical students, residents, fellows) as well as junior/mid-career faculty.
Children and young adults with sickle cell disease, thalassemia and general hematology conditions. Also practice management and quality/safety improvement.
Certifications and Licenses
Pediatric Hematology-Oncology | |
Pediatrics |
Training Experience
2001 | Residency, Northwestern University, McGaw Medical Center (Children’s Memorial Hospital) |
2004 | Fellowship, Johns Hopkins Hospital |
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Medicine, MD, Northwestern University
… → 1997
Research interests keywords
- Exercise Physiology
- Health Disparities
- Hematology
- Medical Education
- Medication Adherence Research
- Patient-Reported Outcomes
- Sickle Cell Disease
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Collaborations and top research areas from the last five years
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Arterial and venous blood clots in sick neonates: Risk factors and risk stratification
Bhat, R. (PD/PI) & Liem, R. I. (Co-Investigator)
8/29/19 → 8/31/50
Project: Research project
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A Multilevel Physical Activity Intervention for South Asian Women and Girls (SAATH)
Mason, M. (PD/PI), Kwon, S. (Co-Investigator) & Liem, R. I. (Co-Investigator)
Northwestern University, National Cancer Institute
8/1/19 → 7/31/24
Project: Research project
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Implementation of evidence based care for the acute treatment of sickle cell disease pain
Alpern, E. R. (PD/PI) & Liem, R. I. (Co-Investigator)
Medical College of Wisconsin, National Heart, Lung, and Blood Institute
9/1/18 → 8/31/21
Project: Research project
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Implementation of evidence based care for the acute treatment of sickle cell disease pain
Alpern, E. R. (PD/PI) & Liem, R. I. (Co-Investigator)
Medical College of Wisconsin, National Heart, Lung, and Blood Institute
9/1/18 → 6/30/20
Project: Research project
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A Reference Equation for Peak Oxygen Uptake for Pediatric Patients Who Undergo Treadmill Cardiopulmonary Exercise Testing
Griffith, G. J., Wang, A. P., Liem, R. I., Carr, M. R., Corson, T. & Ward, K., Feb 1 2024, In: American Journal of Cardiology. 212, p. 41-47 7 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
COVID-19 mRNA vaccination responses in individuals with sickle cell disease: An ASH RC Sickle Cell Research Network Study
Anderson, A. R., Strouse, J. J., Manwani, D., Brandow, A. M., Vichinsky, E., Campbell, A., Leavey, P. J., Nero, A., Ibrahim, I. F., Field, J. J., Baer, A., Soto-Calderon, H., Vincent, L., Zhao, Y., Santos, J. J. S., Hensley, S. E., Mortier, N., Lanzkron, S., Neuberg, D. & Abrams, C. S. & 24 others, , Sep 10 2024, In: Blood Advances. 8, 17, p. 4549-4553 5 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Development of a Pediatric Cardiology Cardiopulmonary Exercise Testing Database
Griffith, G., Liem, R. I., Carr, M., Corson, T. & Ward, K., Aug 2024, In: Pediatric cardiology. 45, 6, p. 1316-1325 10 p.Research output: Contribution to journal › Article › peer-review
6 Scopus citations -
Exagamglogene Autotemcel for Severe Sickle Cell Disease
CLIMB SCD-121 Study Group, May 9 2024, In: New England Journal of Medicine. 390, 18, p. 1649-1662 14 p.Research output: Contribution to journal › Article › peer-review
71 Scopus citations -
Exagamglogene Autotemcel for Transfusion-Dependent β-Thalassemia
CLIMB THAL-111 Study Group, May 9 2024, In: New England Journal of Medicine. 390, 18, p. 1663-1676 14 p.Research output: Contribution to journal › Article › peer-review
33 Scopus citations
Datasets
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Determining the longitudinal validity and meaningful differences in HRQL of the PedsQL™ Sickle Cell Disease Module
Panepinto, J. A. (Creator), Paul, S. J. (Contributor), Badaki-Makun, O. (Contributor), Darbari, D. S. (Creator), Chumpitazi, C. E. (Creator), Airewele, G. E. (Contributor), Ellison, A. M. (Creator), Smith-Whitley, K. (Creator), Mahajan, P. (Creator), Sarnaik, S. A. (Contributor), Charles Casper, T. (Contributor), Cook, L. J. (Creator), Leonard, J. (Creator), Hulbert, M. L. (Creator), Powell, E. C. (Creator), Liem, R. I. (Creator), Hickey, R. (Creator), Krishnamurti, L. (Contributor), Hillery, C. A. (Creator) & Brousseau, D. C. (Creator), figshare, 2017
DOI: 10.6084/m9.figshare.c.3801574, https://figshare.com/collections/Determining_the_longitudinal_validity_and_meaningful_differences_in_HRQL_of_the_PedsQL_Sickle_Cell_Disease_Module/3801574
Dataset