• 758 Citations
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Personal profile

Research Interests

I am the Director of the Comprehensive Sickle Cell Program at Ann & Robert H. Lurie Children's Hospital of Chicago. My clinical interests center on hemoglobin disorders, including pediatric and adult sickle cell disease and thalassemia. I am also a clinical investigator with active research programs in these areas. My major research interests focus on exercise responses, inflammation and vascular function as well as their impact on cardiopulmonary fitness, clinical outcomes and physical functioning in children and young adults with sickle cell anemia. I am also the principal investigator of several other protocols at Lurie Children's Hospital that are aligned with my interests in exercise physiology, free-living physical activity, habitual exercise patterns and aerobic training in this population. Other areas of clinical and research focus include patient-reported outcomes, quality of life, transition to adult care, patient-centered medical homes, health disparities and parental decision making regarding research participation in sickle cell disease and thalassemia.

Cardiopulmonary fitness, exercise responses, aerobic training, free-living physical activity, exercise prescription, inflammation, and endothelial function in children and young adults with sickle cell disease. Also career development of trainees (medical students, residents, fellows) as well as junior/mid-career faculty.

Children and young adults with sickle cell disease, thalassemia and general hematology conditions. Also practice management and quality/safety improvement.

Certifications and Licenses

Pediatric Hematology-Oncology

Training Experience

2001Residency, Northwestern University, McGaw Medical Center (Children’s Memorial Hospital)
2004Fellowship, Johns Hopkins Hospital

Education/Academic qualification

MD, Northwestern University Feinberg School of Medicine

… → 1997

Research interests

  • Exercise Physiology
  • Health Disparities
  • Hematology
  • Medical Education
  • Medication Adherence Research
  • Patient-Reported Outcomes
  • Sickle Cell Disease

Fingerprint Dive into the research topics where Robert I Liem is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 1 Similar Profiles
Sickle Cell Anemia Medicine & Life Sciences
Young Adult Medicine & Life Sciences
Hydroxyurea Medicine & Life Sciences
Acute Chest Syndrome Medicine & Life Sciences
Pediatrics Medicine & Life Sciences
Exercise Medicine & Life Sciences
Quality of Life Medicine & Life Sciences
Hemoglobins Medicine & Life Sciences

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Grants 2011 2022

Research Output 2003 2019

Identifying clinical and research priorities in sickle cell lung disease an official American Thoracic Society workshop report

American Thoracic Society Assembly on Pediatrics, Jan 1 2019, In : Annals of the American Thoracic Society. 16, 9, p. E17-E32

Research output: Contribution to journalArticle

Sickle Cell Anemia
Lung Diseases
Acute Chest Syndrome
Sickle Cell Anemia
Erythrocyte Count

Balancing exercise risk and benefits: Lessons learned from sickle cell trait and sickle cell anemia

Liem, R. I., Nov 30 2018, In : Hematology. 2018, 1, p. 418-425 8 p.

Research output: Contribution to journalArticle

Sickle Cell Trait
Sickle Cell Anemia
7 Citations (Scopus)

Beliefs about hydroxyurea in youth with sickle cell disease

Badawy, S. M., Thompson, A. A. & Liem, R. I., Sep 1 2018, In : Hematology/ Oncology and Stem Cell Therapy. 11, 3, p. 142-148 7 p.

Research output: Contribution to journalArticle

Sickle Cell Anemia
Quality of Life
Visual Analog Scale
Young Adult

Exercise capacity and clinical outcomes in adults followed in the Cooperative Study of Sickle Cell Disease (CSSCD)

Badawy, S. M., Payne, A. B., Rodeghier, M. J. & Liem, R. I., Oct 1 2018, In : European Journal of Haematology. 101, 4, p. 532-541 10 p.

Research output: Contribution to journalArticle

Sickle Cell Anemia
Acute Chest Syndrome
Sickle Hemoglobin