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Robert I Liem

  • 881 Citations
20032020

Research output per year

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Personal profile

Research Interests

I am the Director of the Comprehensive Sickle Cell Program at Ann & Robert H. Lurie Children's Hospital of Chicago. My clinical interests center on hemoglobin disorders, including pediatric and adult sickle cell disease and thalassemia. I am also a clinical investigator with active research programs in these areas. My major research interests focus on exercise responses, inflammation and vascular function as well as their impact on cardiopulmonary fitness, clinical outcomes and physical functioning in children and young adults with sickle cell anemia. I am also the principal investigator of several other protocols at Lurie Children's Hospital that are aligned with my interests in exercise physiology, free-living physical activity, habitual exercise patterns and aerobic training in this population. Other areas of clinical and research focus include patient-reported outcomes, quality of life, transition to adult care, patient-centered medical homes, health disparities and parental decision making regarding research participation in sickle cell disease and thalassemia.

Cardiopulmonary fitness, exercise responses, aerobic training, free-living physical activity, exercise prescription, inflammation, and endothelial function in children and young adults with sickle cell disease. Also career development of trainees (medical students, residents, fellows) as well as junior/mid-career faculty.

Children and young adults with sickle cell disease, thalassemia and general hematology conditions. Also practice management and quality/safety improvement.

Certifications and Licenses

Pediatric Hematology-Oncology
Pediatrics

Training Experience

2001Residency, Northwestern University, McGaw Medical Center (Children’s Memorial Hospital)
2004Fellowship, Johns Hopkins Hospital

Education/Academic qualification

MD, Northwestern University Feinberg School of Medicine

… → 1997

Research interests

  • Exercise Physiology
  • Health Disparities
  • Hematology
  • Medical Education
  • Medication Adherence Research
  • Patient-Reported Outcomes
  • Sickle Cell Disease

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Grants

Arterial and venous blood clots in sick neonates: Risk factors and risk stratification

Bhat, R. & Liem, R. I.

Bristol-Myers Squibb Company

8/29/19 → 8/31/50

Project: Research project

A Multilevel Physical Activity Intervention for South Asian Women and Girls (SAATH)

Kwon, S., Liem, R. I. & Mason, M.

Northwestern University, National Institute on Minority Health and Health Disparities

8/1/19 → 6/30/24

Project: Research project

Implementation of evidence based care for the acute treatment of sickle cell disease pain

Alpern, E. R. & Liem, R. I.

Medical College of Wisconsin

9/1/18 → 6/30/20

Project: Research project

Implementation of evidence based care for the acute treatment of sickle cell disease pain

Alpern, E. R., Liem, R. I. & Liem, R. I.

Medical College of Wisconsin, National Heart, Lung, and Blood Institute

9/1/18 → 6/30/20

Project: Research project

GBT 440-032 A Phase 3, Randomized, Double-Blind, Placebo Controlled Study of Voxelotor (GBT440) in Pediatric Participants with Sickle Cell Disease and an Open-label Study in Infants with Sickle Cell Disease (HOPE Kids 2)

Liem, R. I.

Global Blood Therapeutics, Inc.

7/25/18 → 7/24/21

Project: Research project

Research Output

Impact of Medicaid expansion on access and healthcare among individuals with sickle cell disease

Kayle, M., Valle, J., Paulukonis, S., Holl, J. L., Tanabe, P., French, D. D., Garg, R., Liem, R. I., Badawy, S. M. & Treadwell, M. J., May 1 2020, In : Pediatric Blood and Cancer. 67, 5, e28152.

Research output: Contribution to journal › Article

    • 1 Scopus citations

    2019 sickle cell disease guidelines by the American Society of Hematology: Methodology, challenges, and innovations

    Hassan Murad, M., Liem, R. I., Lang, E. S., Akl, E. A., Meerpohl, J. J., DeBaun, M. R., Tisdale, J. F., Brandow, A. M., Lanzkron, S. M., Chou, S. T., Webb, S. & Mustafa, R. A., Jan 1 2019, In : Blood Advances. 3, 23, p. 3945-3950 6 p.

    Research output: Contribution to journal › Review article

    Open Access
    • 3 Scopus citations

    American Society of Hematology 2019 guidelines for sickle cell disease: Cardiopulmonary and kidney disease

    Liem, R. I., Lanzkron, S., Coates, T. D., DeCastro, L., Desai, A. A., Ataga, K. I., Cohen, R. T., Haynes, J., Osunkwo, I., Lebensburger, J. D., Lash, J. P., Wun, T., Verhovsek, M., Ontala, E., Blaylark, R., Alahdab, F., Katabi, A. & Mustafa, R. A., Jan 1 2019, In : Blood Advances. 3, 23, p. 3867-3897 31 p.

    Research output: Contribution to journal › Article

    Open Access
    • 2 Scopus citations

    Identifying clinical and research priorities in sickle cell lung disease an official American Thoracic Society workshop report

    American Thoracic Society Assembly on Pediatrics, Jan 1 2019, In : Annals of the American Thoracic Society. 16, 9, p. E17-E32

    Research output: Contribution to journal › Article

    • 4 Scopus citations

    Nucleated Red Blood Cells in Children with Sickle Cell Disease Hospitalized for Pain

    Ballantine, J. D., Kwon, S. & Liem, R. I., Nov 1 2019, In : Journal of pediatric hematology/oncology. 41, 8, p. E487-E492

    Research output: Contribution to journal › Article

    • 1 Scopus citations