Grants per year
Personal profile
Research Interests
I am interested in the mechanisms of pathogenesis and treatment of a variety of allergic and inflammatory diseases associated with allergy. These include chronic rhinosinusitis, asthma, hay fever, rhinitis, food allergy and others. We also study the mechanisms of action of antiinflammatory glucocorticoids. Our studies focus on the molecular and cellular mechanisms underlying disease and steroid action as well as developing strategies to for new treatments.
Training Experience
1981 | Fellowship, Johns Hopkins University School of Medicine |
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Pharmacology and Toxicology, PhD, University of California at Davis
… → 1979
Pharmacology and Toxicology, PhD, University of California-Davis
… → 1979
Research interests keywords
- Allergies
- Asthma
- Immunology
- Inflammation
Fingerprint
- 1 Similar Profiles
Collaborations and top research areas from the last five years
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Northwestern University Allergy and Immunology Research (NUAIR) Program
Berdnikovs, S. (PD/PI), Eisenbarth, S. C. (PD/PI), Schleimer, R. P. (PD/PI), Berdnikovs, S. (Co-Investigator), Bochner, B. S. (Co-Investigator) & Saltoun, C. A. (Other)
National Institute of Allergy and Infectious Diseases
8/1/20 → 7/31/25
Project: Research project
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Northwestern University Allergy and Immunology Research (NUAIR) Program
Bochner, B. S. (PD/PI), Schleimer, R. P. (PD/PI), Berdnikovs, S. (Other) & Saltoun, C. A. (Other)
National Institute of Allergy and Infectious Diseases
8/1/20 → 7/31/25
Project: Research project
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Chronic Rhinosinusitis Integrative Studies Program 2 (CRISP2)
Kato, A. (PD/PI), Schleimer, R. P. (PD/PI), Schleimer, R. P. (PD/PI), Schleimer, R. P. (PD/PI), Schleimer, R. P. (Co-Investigator), Lindholm, P. F. (Other), Lindholm, P. F. (Other), Lindholm, P. F. (Other), Rademaker, A. W. (Other), Rademaker, A. W. (Other), Rademaker, A. W. (Other), Stevens, W. (Other), Stevens, W. (Other), Stevens, W. (Other), Welch, K. C. (Other), Welch, K. C. (Other) & Welch, K. C. (Other)
National Institute of Allergy and Infectious Diseases
8/15/19 → 7/31/25
Project: Research project
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Project 1: Mechanisms of barrier dysfunction and tissue hyperplasia in CRS
Kato, A. (PD/PI), Schleimer, R. P. (PD/PI), Schleimer, R. P. (PD/PI), Schleimer, R. P. (PD/PI), Berdnikovs, S. (Co-Investigator), Berdnikovs, S. (Co-Investigator), Berdnikovs, S. (Co-Investigator), Hulse, K. E. (Co-Investigator), Hulse, K. E. (Co-Investigator), Hulse, K. E. (Co-Investigator), Kern, R. C. (Co-Investigator), Kern, R. C. (Co-Investigator), Kern, R. C. (Co-Investigator), Peters, A. T. (Co-Investigator), Peters, A. T. (Co-Investigator), Peters, A. T. (Co-Investigator), Tan, B.K.-H. (Co-Investigator), Tan, B.K.-H. (Co-Investigator) & Tan, B.K.-H. (Co-Investigator)
National Institute of Allergy and Infectious Diseases
8/15/19 → 7/31/25
Project: Research project
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Influenza virus receptors on human airway epithelial cells
Schleimer, R. P. (PD/PI) & Schleimer, R. P. (PD/PI)
Scripps Research Institute, National Institute of Allergy and Infectious Diseases
8/1/20 → 7/31/24
Project: Research project
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Analysis of human neutrophils from nasal polyps by single-cell RNA sequencing reveals roles of neutrophils in chronic rhinosinusitis
Iwasaki, N., Poposki, J. A., Kidoguchi, M., Oka, A., Klingler, A. I., Stevens, W. W., Suh, L. A., Bai, J., Peters, A. T., Grammer, L. C., Welch, K. C., Smith, S. S., Conley, D. B., Bochner, B. S., Schleimer, R. P., Kern, R. C., Tan, B. K. & Kato, A., 2024, (Accepted/In press) In: Journal of Allergy and Clinical Immunology.Research output: Contribution to journal › Article › peer-review
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Associations Between Chronic Rhinosinusitis and the Development of Non–Cystic Fibrosis Bronchiectasis
Kim, S. L., Schwartz, B. S., Vu, T. H., Conley, D. B., Grammer, L. C., Guo, A., Kato, A., Kern, R. C., Prickett, M. H., Schleimer, R. P., Smith, S., Stevens, W. W., Suh, L., Tan, B. K., Welch, K. C. & Peters, A. T., Nov 2024, In: Journal of Allergy and Clinical Immunology: In Practice. 12, 11, p. 3116-3122.e2Research output: Contribution to journal › Article › peer-review
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IL-13 and IL-13–induced periostin levels are specifically decreased in patients following endoscopic sinus surgery for chronic rhinosinusitis
Harmon, R., Schneider, A. L., Bai, J., Racette, S. D., Reddy, A. T., Huang, J. H., Lehmann, D. S., Price, C. P. E., Rodeghiero, S., Agarwal, A., Eide, J. G., Dong, S., Conley, D. B., Welch, K. C., Kern, R. C., Shintani-Smith, S., Peters, A. T., Kato, A., Stevens, W. W. & Muhammad, L. N. & 2 others, , May 2024, In: Journal of Allergy and Clinical Immunology. 153, 5, p. 1292-1305 14 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
Increased autoreactivity and maturity of EBI2+ antibody-secreting cells from nasal polyps
Bai, J., Kato, A., Hulse, K. E., Wechsler, J. B., Gujar, V., Poposki, J. A., Harmon, R., Iwasaki, N., Wang, B. F., Huang, J. H., Stevens, W. W., Conley, D. B., Welch, K. C., Kern, R. C., Peters, A. T., Eisenbarth, S. C., Schleimer, R. P. & Tan, B.K.-H., Sep 10 2024, In: JCI Insight. 9, 17, e177729.Research output: Contribution to journal › Article › peer-review
Open Access -
Reply to “correspondence to ‘association between chronic rhinosinusitis and new onset asthma implications for prevention’”
Schwartz, B. S., Hirsch, A. G., Bandeen-Roche, K., Kato, A. & Schleimer, R., May 2024, In: Allergy: European Journal of Allergy and Clinical Immunology. 79, 5, p. 1394-1395 2 p.Research output: Contribution to journal › Letter › peer-review
Datasets
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Additional file 9 of Multi-omics colocalization with genome-wide association studies reveals a context-specific genetic mechanism at a childhood onset asthma risk locus
Soliai, M. M. (Creator), Kato, A. (Creator), Helling, B. A. (Creator), Stanhope, C. T. (Creator), Norton, J. E. (Creator), Naughton, K. A. (Creator), Klinger, A. I. (Creator), Thompson, E. E. (Creator), Clay, S. M. (Creator), Kim, S. (Creator), Celedón, J. C. (Creator), Gern, J. E. (Creator), Jackson, D. J. (Creator), Altman, M. C. (Creator), Kern, R. C. (Creator), Tan, B. K. (Creator), Schleimer, R. P. (Creator), Nicolae, D. L. (Creator), Pinto, J. M. (Creator) & Ober, C. (Creator), figshare, 2021
DOI: 10.6084/m9.figshare.16780901, https://springernature.figshare.com/articles/dataset/Additional_file_9_of_Multi-omics_colocalization_with_genome-wide_association_studies_reveals_a_context-specific_genetic_mechanism_at_a_childhood_onset_asthma_risk_locus/16780901
Dataset
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Additional file 5 of Multi-omics colocalization with genome-wide association studies reveals a context-specific genetic mechanism at a childhood onset asthma risk locus
Soliai, M. M. (Creator), Kato, A. (Creator), Helling, B. A. (Creator), Stanhope, C. T. (Creator), Norton, J. E. (Creator), Naughton, K. A. (Creator), Klinger, A. I. (Creator), Thompson, E. E. (Creator), Clay, S. M. (Creator), Kim, S. (Creator), Celedón, J. C. (Creator), Gern, J. E. (Creator), Jackson, D. J. (Creator), Altman, M. C. (Creator), Kern, R. C. (Creator), Tan, B. K. (Creator), Schleimer, R. P. (Creator), Nicolae, D. L. (Creator), Pinto, J. M. (Creator) & Ober, C. (Creator), figshare, 2021
DOI: 10.6084/m9.figshare.16780883, https://springernature.figshare.com/articles/dataset/Additional_file_5_of_Multi-omics_colocalization_with_genome-wide_association_studies_reveals_a_context-specific_genetic_mechanism_at_a_childhood_onset_asthma_risk_locus/16780883
Dataset
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Gene expression analysis of Chronic rhinosinusitis
Kato, A. (Contributor), Kern, R. C. (Contributor) & Schleimer, R. P. (Contributor), Gene Expression Omnibus, Mar 27 2012
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE36830
Dataset
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Additional file 10 of Multi-omics colocalization with genome-wide association studies reveals a context-specific genetic mechanism at a childhood onset asthma risk locus
Soliai, M. M. (Creator), Kato, A. (Creator), Helling, B. A. (Creator), Stanhope, C. T. (Creator), Norton, J. E. (Creator), Naughton, K. A. (Creator), Klinger, A. I. (Creator), Thompson, E. E. (Creator), Clay, S. M. (Creator), Kim, S. (Creator), Celedón, J. C. (Creator), Gern, J. E. (Creator), Jackson, D. J. (Creator), Altman, M. C. (Creator), Kern, R. C. (Creator), Tan, B. K. (Creator), Schleimer, R. P. (Creator), Nicolae, D. L. (Creator), Pinto, J. M. (Creator) & Ober, C. (Creator), figshare, 2021
DOI: 10.6084/m9.figshare.16780853, https://springernature.figshare.com/articles/dataset/Additional_file_10_of_Multi-omics_colocalization_with_genome-wide_association_studies_reveals_a_context-specific_genetic_mechanism_at_a_childhood_onset_asthma_risk_locus/16780853
Dataset
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Additional file 2 of Multi-omics colocalization with genome-wide association studies reveals a context-specific genetic mechanism at a childhood onset asthma risk locus
Soliai, M. M. (Creator), Kato, A. (Creator), Helling, B. A. (Creator), Stanhope, C. T. (Creator), Norton, J. E. (Creator), Naughton, K. A. (Creator), Klinger, A. I. (Creator), Thompson, E. E. (Creator), Clay, S. M. (Creator), Kim, S. (Creator), Celedón, J. C. (Creator), Gern, J. E. (Creator), Jackson, D. J. (Creator), Altman, M. C. (Creator), Kern, R. C. (Creator), Tan, B. K. (Creator), Schleimer, R. P. (Creator), Nicolae, D. L. (Creator), Pinto, J. M. (Creator) & Ober, C. (Creator), figshare, 2021
DOI: 10.6084/m9.figshare.16780874, https://springernature.figshare.com/articles/dataset/Additional_file_2_of_Multi-omics_colocalization_with_genome-wide_association_studies_reveals_a_context-specific_genetic_mechanism_at_a_childhood_onset_asthma_risk_locus/16780874
Dataset