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Robert P Schleimer

  • 20916 Citations
1976 …2024

Research output per year

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Personal profile

Research Interests

I am interested in the mechanisms of pathogenesis and treatment of a variety of allergic and inflammatory diseases associated with allergy. These include chronic rhinosinusitis, asthma, hay fever, rhinitis, food allergy and others. We also study the mechanisms of action of antiinflammatory glucocorticoids. Our studies focus on the molecular and cellular mechanisms underlying disease and steroid action as well as developing strategies to for new treatments.

Training Experience

1981Fellowship, Johns Hopkins University School of Medicine

Education/Academic qualification

PhD, University of California, Davis

… → 1979

Research interests

  • Allergies
  • Asthma
  • Immunology
  • Inflammation

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Grants

Project 1: Mechanisms of barrier dysfunction and tissue hyperplasia in CRS

Berdnikovs, S., Hulse, K. E., Kern, R. C., Peters, A. T., Schleimer, R. P. & Tan, B. K.

National Institute of Allergy and Infectious Diseases

8/15/19 → 7/31/24

Project: Research project

    • Chronic Rhinosinusitis Integrative Studies Program 2 (CRISP2)

    Lindholm, P. F., Rademaker, A. W., Schleimer, R. P., Stevens, W. & Welch, K. C.

    National Institute of Allergy and Infectious Diseases

    8/15/19 → 7/31/24

    Project: Research project

    • 5-laser 30-parameter FACSymphony-S6 SORP Cell Sorter from BD Biosciences

    Abecassis, M. M., Bharat, A., Budinger, G. S., D'Aquila, R. T., Hope, T. J., Kato, A., Le Poole, I. C., Lesniak, M. S., Luo, X., Misharin, A., Perlman, H. R., Schleimer, R. P., Singer, B., Swaminathan, S., Sznajder, J. I., Tetreault, M., Thorp, E. B. & Wunderink, R. G.

    Office of the Director, National Institutes of Health

    8/8/19 → 8/7/20

    Project: Research project

    • Type-2 inflammation mediates olfactory loss in Chronic Rhinosinusitis: mechanisms and therapeutic opportunities

    Avram, M. J., Chmiel, J. S., Schleimer, R. P. & Tan, B. K.

    National Institute on Deafness and Other Communication Disorders

    7/23/18 → 6/30/23

    Project: Research project

    • Autoantibody mediated pathogenesis in chronic rhinosinusitis with nasal polyps: mechanisms and consequences

    Hulse, K. E., Schleimer, R. P. & Tan, B. K.

    National Institute of Allergy and Infectious Diseases

    5/25/18 → 4/30/23

    Project: Research project

    • Research Output

    Clinical factors associated with acute exacerbations of chronic rhinosinusitis

    Kwah, J. H., Somani, S. N., Stevens, W. W., Kern, R. C., Smith, S. S., Welch, K. C., Conley, D. B., Tan, B. K., Grammer, L. C., Yang, A., Schleimer, R. P. & Peters, A. T., Jan 1 2020, (Accepted/In press) In : Journal of Allergy and Clinical Immunology.

    Research output: Contribution to journal › Article

    • Common fibrin deposition and tissue plasminogen activator downregulation in nasal polyps with distinct inflammatory endotypes

    Chen, C. L., Yao, Y., Pan, L., Hu, S. T., Ma, J., Wang, Z. C., Kern, R. C., Schleimer, R. P. & Liu, Z., Jan 1 2020, (Accepted/In press) In : Journal of Allergy and Clinical Immunology.

    Research output: Contribution to journal › Article

    Open Access

    Formation of nasal polyps: The roles of innate type 2 inflammation and deposition of fibrin

    Takabayashi, T. & Schleimer, R. P., Mar 2020, In : Journal of Allergy and Clinical Immunology. 145, 3, p. 740-750 11 p.

    Research output: Contribution to journal › Review article

    Open Access

    • Radiologic sinus inflammation and symptoms of chronic rhinosinusitis in a population-based sample

    Hirsch, A. G., Nordberg, C., Bandeen-Roche, K., Tan, B. K., Schleimer, R. P., Kern, R. C., Sundaresan, A., Pinto, J. M., Kennedy, T. L., Greene, J. S., Kuiper, J. R. & Schwartz, B. S., Apr 1 2020, In : Allergy: European Journal of Allergy and Clinical Immunology. 75, 4, p. 911-920 10 p.

    Research output: Contribution to journal › Article

    • 1 Scopus citations

    Role of RANK-L as a potential inducer of ILC2-mediated type 2 inflammation in chronic rhinosinusitis with nasal polyps

    Ogasawara, N., Poposki, J. A., Klingler, A. I., Tan, B. K., Hulse, K. E., Stevens, W. W., Peters, A. T., Grammer, L. C., Welch, K. C., Smith, S. S., Conley, D. B., Raviv, J. R., Soroosh, P., Takano, K. I., Himi, T., Kern, R. C., Schleimer, R. P. & Kato, A., Jan 1 2020, In : Mucosal Immunology. 13, 1, p. 86-95 10 p.

    Research output: Contribution to journal › Article

    • 1 Scopus citations