Roger Stupp

  • 41919 Citations
1990 …2023

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2020

cIMPACT-NOW update 5: recommended grading criteria and terminologies for IDH-mutant astrocytomas

Brat, D. J., Aldape, K., Colman, H., Figrarella-Branger, D., Fuller, G. N., Giannini, C., Holland, E. C., Jenkins, R. B., Kleinschmidt-DeMasters, B., Komori, T., Kros, J. M., Louis, D. N., McLean, C., Perry, A., Reifenberger, G., Sarkar, C., Stupp, R., van den Bent, M. J., von Deimling, A. & Weller, M., Mar 1 2020, In : Acta Neuropathologica. 139, 3, p. 603-608 6 p.

Research output: Contribution to journalArticle

2 Scopus citations

Ultrasound-mediated delivery of paclitaxel for glioma: A comparative study of distribution, toxicity, and efficacy of albumin-bound versus cremophor formulations

Zhang, D. Y., Dmello, C., Chen, L., Arrieta, V. A., Gonzalez-Buendia, E., Robert Kane, J., Magnusson, L. P., Baran, A., David James, C., Horbinski, C., Carpentier, A., Desseaux, C., Canney, M., Muzzio, M., Stupp, R. & Sonabend, A. M., Jan 15 2020, In : Clinical Cancer Research. 26, 2, p. 477-486 10 p.

Research output: Contribution to journalArticle

Use of metformin and outcome of patients with newly diagnosed glioblastoma: Pooled analysis

for the EORTC Brain Tumor Group, Feb 1 2020, In : International Journal of Cancer. 146, 3, p. 803-809 7 p.

Research output: Contribution to journalArticle

2 Scopus citations
2019

Changing Paradigms in the Treatment of Brain Metastases

Stupp, R., Nov 1 2019, In : Journal of oncology practice. 15, 11, p. 573-574 2 p.

Research output: Contribution to journalArticle

Imaging tryptophan uptake with positron emission tomography in glioblastoma patients treated with indoximod

Lukas, R. V., Juhász, C., Wainwright, D. A., James, C. D., Kennedy, E., Stupp, R. & Lesniak, M. S., Jan 15 2019, In : Journal of Neuro-Oncology. 141, 1, p. 111-120 10 p.

Research output: Contribution to journalArticle

6 Scopus citations

Impact of Radiation Target Volume on Health-Related Quality of Life in Patients With Low-Grade Glioma in the 2-Year Period Post Treatment: A Secondary Analysis of the EORTC 22033-26033

Dirven, L., Reijneveld, J. C., Taphoorn, M. J. B., Coens, C., El-Badawy, S. A., Tzuk-Shina, T., Bravo-Marques, J., Back, M., Stalpers, L. J. A., Stupp, R., Baumert, B. G. & Seidel, C., May 1 2019, In : International Journal of Radiation Oncology Biology Physics. 104, 1, p. 90-100 11 p.

Research output: Contribution to journalArticle

2 Scopus citations

MGMT promoter methylation cutoff with safety margin for selecting glioblastoma patients into trials omitting temozolomide: A pooled analysis of four clinical trials

Hegi, M. E., Genbrugge, E., Gorlia, T., Stupp, R., Gilbert, M. R., Chinot, O. L., Burt Nabors, L., Jones, G., Van Criekinge, W., Straub, J. & Weller, M., Jan 1 2019, In : Clinical Cancer Research. 25, 6, p. 1809-1816 8 p.

Research output: Contribution to journalArticle

9 Scopus citations

MGMT promoter methylation status testing to guide therapy for glioblastoma: Refining the approach based on emerging evidence and current challenges

Mansouri, A., Hachem, L. D., Mansouri, S., Nassiri, F., Laperriere, N. J., Xia, D., Lindeman, N. I., Wen, P. Y., Chakravarti, A., Mehta, M. P., Hegi, M. E., Stupp, R., Aldape, K. D. & Zadeh, G., Feb 14 2019, In : Neuro-oncology. 21, 2, p. 167-178 12 p.

Research output: Contribution to journalArticle

12 Scopus citations

Multimodal Treatment in Operable Stage III NSCLC: A Pooled Analysis on Long-Term Results of Three SAKK trials (SAKK 16/96, 16/00, and 16/01)

Swiss Group for Clinical Cancer Research (SAKK), Jan 2019, In : Journal of Thoracic Oncology. 14, 1, p. 115-123 9 p.

Research output: Contribution to journalArticle

Overcoming the blood-brain barrier with an implantable ultrasound device

Sonabend, A. M. & Stupp, R., Jan 1 2019, In : Clinical Cancer Research. 25, 13, p. 3750-3752 3 p.

Research output: Contribution to journalArticle

2 Scopus citations

Symptom clusters in newly diagnosed glioma patients: Which symptom clusters are independently associated with functioning and global health status?

Coomans, M. B., Dirven, L., Aaronson, N. K., Baumert, B. G., Van Den Bent, M., Bottomley, A., Brandes, A. A., Chinot, O., Coens, C., Gorlia, T., Herrlinger, U., Keime-Guibert, F., Malmström, A., Martinelli, F., Stupp, R., Talacchi, A., Weller, M., Wick, W., Reijneveld, J. C. & Taphoorn, M. J. B., Nov 4 2019, In : Neuro-oncology. 21, 11, p. 1447-1457 11 p.

Research output: Contribution to journalArticle

1 Scopus citations
4 Scopus citations
2018

Aberrant Lck signal via CD28 Costimulation augments antigen-specific functionality and tumor control by redirected T cells with PD-1 blockade in humanized mice

Gulati, P., Ruhl, J., Kannan, A., Pircher, M., Schuberth, P., Nytko, K. J., Pruschy, M., Sulser, S., Haefner, M., Jensen, S., Soltermann, A., Jungraithmayr, W., Eisenring, M., Winder, T., Samaras, P., Tabor, A., Stenger, R., Stupp, R., Weder, W., Renner, C. & 2 others, Munz, C. & Petrausch, U., Aug 15 2018, In : Clinical Cancer Research. 24, 16, p. 3981-3993 13 p.

Research output: Contribution to journalArticle

6 Scopus citations

Adjuvant treatment of resectable biliary tract cancer with cisplatin plus gemcitabine: A prospective single center phase II study

Siebenhüner, A. R., Seifert, H., Bachmann, H., Seifert, B., Winder, T., Feilchenfeldt, J., Breitenstein, S., Clavien, P. A., Stupp, R., Knuth, A., Pestalozzi, B. & Samaras, P., Jan 11 2018, In : BMC cancer. 18, 1, 72.

Research output: Contribution to journalArticle

5 Scopus citations

Associations of anticoagulant use with outcome in newly diagnosed glioblastoma

Le Rhun, E., Genbrugge, E., Stupp, R., Chinot, O. L., Nabors, L. B., Cloughesy, T., Reardon, D. A., Wick, W., Gorlia, T. & Weller, M., Sep 2018, In : European Journal of Cancer. 101, p. 95-104 10 p.

Research output: Contribution to journalArticle

4 Scopus citations

B cell-rich non-neoplastic sentinel lesion preceding primary central nervous system lymphoma

Javier, R., Shaikh, N., Lesniak, M. S., Sonabend, A., Stupp, R., Behdad, A. & Horbinski, C., Jun 5 2018, In : Diagnostic pathology. 13, 1, 37.

Research output: Contribution to journalArticle

Developing an Integrative Treatment Program for Cancer-Related Fatigue Using Stakeholder Engagement – A Qualitative Study

Canella, C., Mikolasek, M., Rostock, M., Beyer, J., Guckenberger, M., Jenewein, J., Linka, E., Six, C., Stoll, S., Stupp, R. & Witt, C. M., Sep 1 2018, In : Integrative Cancer Therapies. 17, 3, p. 762-773 12 p.

Research output: Contribution to journalArticle

1 Scopus citations

Diagnostic value of 18F-fluordesoxyglucose positron emission tomography for patients with brain metastasis from unknown primary site

Wolpert, F., Weller, M., Berghoff, A. S., Rushing, E., Füreder, L. M., Petyt, G., Leske, H., Andratschke, N., Regli, L., Neidert, M. C., Stupp, R., Stahel, R., Dummer, R., Frauenfelder, T., Roth, P., Reyns, N., Kaufmann, P. A., Preusser, M. & Le Rhun, E., Jun 2018, In : European Journal of Cancer. 96, p. 64-72 9 p.

Research output: Contribution to journalArticle

4 Scopus citations

Do statins, ACE inhibitors or sartans improve outcome in primary glioblastoma?

For the EORTC Brain Tumor Group and on behalf of the CENTRIC and CORE Clinical Trial Groups, May 1 2018, In : Journal of Neuro-Oncology. 138, 1, p. 163-171 9 p.

Research output: Contribution to journalArticle

9 Scopus citations

Expression-based intrinsic glioma subtypes are prognostic in low-grade gliomas of the EORTC22033-26033 clinical trial

Gao, Y., Weenink, B., van den Bent, M. J., Erdem-Eraslan, L., Kros, J. M., Sillevis Smitt, P. A. E., Hoang-Xuan, K., Brandes, A. A., Vos, M., Dhermain, F., Enting, R., Ryan, G. F., Chinot, O., Ben Hassel, M., van Linde, M. E., Mason, W. P., Gijtenbeek, J. M. M., Balana, C., von Deimling, A., Gorlia, T. & 4 others, Stupp, R., Hegi, M. E., Baumert, B. G. & French, P. J., May 2018, In : European Journal of Cancer. 94, p. 168-178 11 p.

Research output: Contribution to journalArticle

5 Scopus citations

IDO1 inhibition synergizes with radiation and PD-1 blockade to durably increase survival against advanced glioblastoma

Ladomersky, E., Zhai, L., Lenzen, A., Lauing, K. L., Qian, J., Scholtens, D. M., Gritsina, G., Sun, X., Liu, Y., Yu, F., Gong, W., Liu, Y., Jiang, B., Tang, T., Patel, R., Platanias, L. C., David James, C., Stupp, R., Lukas, R. V., Binder, D. C. & 1 others, Wainwright, D. A., Jun 1 2018, In : Clinical Cancer Research. 24, 11, p. 2559-2573 15 p.

Research output: Contribution to journalArticle

23 Scopus citations

Influence of treatment with tumor-treating fields on health-related quality of life of patients with newly diagnosed glioblastoma a secondary analysis of a randomized clinical trial

Taphoorn, M. J. B., Dirven, L., Kanner, A. A., Lavy-Shahaf, G., Weinberg, U., Taillibert, S., Toms, S. A., Honnorat, J., Chen, T. C., Sroubek, J., David, C., Idbaih, A., Easaw, J. C., Kim, C. Y., Bruna, J., Hottinger, A. F., Kew, Y., Roth, P., Desai, R., Villano, J. L. & 3 others, Kirson, E. D., Ram, Z. & Stupp, R., Apr 2018, In : JAMA Oncology. 4, 4, p. 495-504 10 p.

Research output: Contribution to journalArticle

23 Scopus citations

Ipilimumab and early signs of pulmonary toxicity in patients with metastastic melanoma: a prospective observational study

Franzen, D., Schad, K., Kowalski, B., Clarenbach, C. F., Stupp, R., Dummer, R. & Kohler, M., Jan 1 2018, In : Cancer Immunology, Immunotherapy. 67, 1, p. 127-134 8 p.

Research output: Contribution to journalArticle

6 Scopus citations

Maturation of tertiary lymphoid structures and recurrence of stage II and III colorectal cancer

Posch, F., Silina, K., Leibl, S., Mündlein, A., Moch, H., Siebenhüner, A., Samaras, P., Riedl, J., Stotz, M., Szkandera, J., Stöger, H., Pichler, M., Stupp, R., van den Broek, M., Schraml, P., Gerger, A., Petrausch, U. & Winder, T., Feb 1 2018, In : OncoImmunology. 7, 2, e1378844.

Research output: Contribution to journalArticle

15 Scopus citations

Mobilization of Hematopoietic Progenitor Cells with Standard- or Reduced-Dose Filgrastim after Vinorelbine in Multiple Myeloma Patients: A Randomized Prospective Single-Center Phase II Study

Samaras, P., Rütti, M. F., Seifert, B., Bachmann, H., Schanz, U., Eisenring, M., Renner, C., Susanne Müller, A. M., Schmidt, A., Mischo, A., Fuchs, I., Bargetzi, M., Manz, M. G., Stupp, R., Petrausch, U. & Stenner-Liewen, F., Apr 2018, In : Biology of Blood and Marrow Transplantation. 24, 4, p. 694-699 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Novel, improved grading system(S) for IDH-mutant astrocytic gliomas

Shirahata, M., Ono, T., Stichel, D., Schrimpf, D., Reuss, D. E., Sahm, F., Koelsche, C., Wefers, A., Reinhardt, A., Huang, K., Sievers, P., Shimizu, H., Nanjo, H., Kobayashi, Y., Miyake, Y., Suzuki, T., Adachi, J. I., Mishima, K., Sasaki, A., Nishikawa, R. & 26 others, Bewerunge-Hudler, M., Ryzhova, M., Absalyamova, O., Golanov, A., Sinn, P., Platten, M., Jungk, C., Winkler, F., Wick, A., Hänggi, D., Unterberg, A., Pfister, S. M., Jones, D. T. W., Van Den Bent, M., Hegi, M., French, P., Baumert, B. G., Stupp, R., Gorlia, T., Weller, M., Capper, D., Korshunov, A., Herold-Mende, C., Wick, W., Louis, D. N. & Von Deimling, A., Apr 23 2018, In : Acta Neuropathologica. 136, 1, p. 153-166 14 p.

Research output: Contribution to journalArticle

57 Scopus citations

Primary central nervous system lymphoma: Part 2: Modern therapeutic management and future directions

Lukas, R. V., Gondi, V., Stupp, R. & Raizer, J. J., Jan 1 2018, In : ONCOLOGY (United States). 32, 2, p. e11-e19

Research output: Contribution to journalArticle

1 Scopus citations

Primary central nervous system lymphoma: Part 1: Epidemiology, diagnosis, staging, and prognosis

Lukas, R. V., Stupp, R., Gondi, V. & Raizer, J. J., Jan 1 2018, In : ONCOLOGY (United States). 32, 1, p. 17-27 11 p.

Research output: Contribution to journalArticle

7 Scopus citations

The DNA methylome of DDR genes and benefit from RT or TMZ in IDH mutant low-grade glioma treated in EORTC 22033

Bady, P., Kurscheid, S., Delorenzi, M., Gorlia, T., van Den Bent, M. J., Hoang-Xuan, K., Vauléon, É., Gijtenbeek, A., Enting, R., Thiessen, B., Chinot, O., Dhermain, F., Brandes, A. A., Reijneveld, J. C., Marosi, C., Taphoorn, M. J. B., Wick, W., von Deimling, A., French, P., Stupp, R. & 2 others, Baumert, B. G. & Hegi, M. E., Apr 1 2018, In : Acta Neuropathologica. 135, 4, p. 601-615 15 p.

Research output: Contribution to journalArticle

23 Scopus citations
2017

Biological activity of tumor-Treating fields in preclinical glioma models

Silginer, M., Weller, M., Stupp, R. & Roth, P., Apr 20 2017, In : Cell Death and Disease. 8, 4, e2753.

Research output: Contribution to journalArticle

23 Scopus citations

Effect of tumor-treating fields plus maintenance temozolomide vs maintenance temozolomide alone on survival in patients with glioblastoma a randomized clinical trial

Stupp, R., Taillibert, S., Kanner, A., Read, W., Steinberg, D. M., Lhermitte, B., Toms, S., Idbaih, A., Ahluwalia, M. S., Fink, K., Di Meco, F., Lieberman, F., Zhu, J. J., Stragliotto, G., Tran, D. D., Brem, S., Hottinger, A. F., Kirson, E. D., Lavy-Shahaf, G., Weinberg, U. & 9 others, Kim, C. Y., Paek, S. H., Nicholas, G., Burna, J., Hirte, H., Weller, M., Palti, Y., Hegi, M. E. & Ram, Z., Dec 19 2017, In : JAMA - Journal of the American Medical Association. 318, 23, p. 2306-2316 11 p.

Research output: Contribution to journalArticle

242 Scopus citations

Efficacious and save use of biosimilar filgrastim for hematopoietic progenitor cell chemo-mobilization with vinorelbine in multiple myeloma patients

Maul, J. T., Stenner-Liewen, F., Seifert, B., Pfrommer, S., Petrausch, U., Kiessling, M. K., Schanz, U., Nair, G., Mischo, A., Taverna, C., Schmidt, A., Bargetzi, M., Stupp, R., Renner, C. & Samaras, P., Feb 1 2017, In : Journal of Clinical Apheresis. 32, 1, p. 21-26 6 p.

Research output: Contribution to journalArticle

8 Scopus citations

Infiltrating T cells increase IDO1 expression in glioblastoma and contribute to decreased patient survival

Zhai, L., Ladomersky, E., Lauing, K. L., Wu, M., Genet, M., Gritsina, G., Győrffy, B., Brastianos, P. K., Binder, D. C., Sosman, J. A., Giles, F. J., James, C. D., Horbinski, C., Stupp, R. & Wainwright, D. A., Nov 1 2017, In : Clinical Cancer Research. 23, 21, p. 6650-6660 11 p.

Research output: Contribution to journalArticle

27 Scopus citations

Interim results from the CATNON trial (EORTC study 26053-22054) of treatment with concurrent and adjuvant temozolomide for 1p/19q non-co-deleted anaplastic glioma: a phase 3, randomised, open-label intergroup study

van den Bent, M. J., Baumert, B., Erridge, S. C., Vogelbaum, M. A., Nowak, A. K., Sanson, M., Brandes, A. A., Clement, P. M., Baurain, J. F., Mason, W. P., Wheeler, H., Chinot, O. L., Gill, S., Griffin, M., Brachman, D. G., Taal, W., Rudà, R., Weller, M., McBain, C., Reijneveld, J. & 21 others, Enting, R. H., Weber, D. C., Lesimple, T., Clenton, S., Gijtenbeek, A., Pascoe, S., Herrlinger, U., Hau, P., Dhermain, F., van Heuvel, I., Stupp, R., Aldape, K., Jenkins, R. B., Dubbink, H. J., Dinjens, W. N. M., Wesseling, P., Nuyens, S., Golfinopoulos, V., Gorlia, T., Wick, W. & Kros, J. M., Oct 7 2017, In : The Lancet. 390, 10103, p. 1645-1653 9 p.

Research output: Contribution to journalArticle

105 Scopus citations

Is more better? the impact of extended adjuvant temozolomide in newly diagnosed glioblastoma: A secondary analysis of EORTC and NRG Oncology/RTOG

Blumenthal, D. T., Gorlia, T., Gilbert, M. R., Kim, M. M., Burt Nabors, L., Mason, W. P., Hegi, M. E., Zhang, P., Golfinopoulos, V., Perry, J. R., Hyun Nam, D., Erridge, S. C., Corn, B. W., Mirimanoff, R. O., Brown, P. D., Baumert, B. G., Mehta, M. P., Van Den Bent, M. J., Reardon, D. A., Weller, M. & 1 others, Stupp, R., Aug 1 2017, In : Neuro-oncology. 19, 8, p. 1119-1126 8 p.

Research output: Contribution to journalArticle

21 Scopus citations

Lomustine and bevacizumab in progressive glioblastoma

Wick, W., Gorlia, T., Bendszus, M., Taphoorn, M., Sahm, F., Harting, I., Brandes, A. A., Taal, W., Domont, J., Idbaih, A., Campone, M., Clement, P. M., Stupp, R., Fabbro, M., Le Rhun, E., Dubois, F., Weller, M., Von Deimling, A., Golfinopoulos, V., Bromberg, J. C. & 3 others, Platten, M., Klein, M. & Van Den Bent, M. J., Nov 16 2017, In : New England Journal of Medicine. 377, 20, p. 1954-1963 10 p.

Research output: Contribution to journalArticle

157 Scopus citations

Molecular-based recursive partitioning analysis model for glioblastoma in the temozolomide era a correlative analysis based on nrg oncology RTOG 0525

Bell, E. H., Pugh, S. L., McElroy, J. P., Gilbert, M. R., Mehta, M., Klimowicz, A. C., Magliocco, A., Bredel, M., Robe, P., Grosu, A. L., Stupp, R., Curran, W., Becker, A. P., Salavaggione, A. L., Barnholtz-Sloan, J. S., Aldape, K., Blumenthal, D. T., Brown, P. D., Glass, J., Souhami, L. & 5 others, Lee, R. J., Brachman, D., Flickinger, J., Won, M. & Chakravarti, A., Jun 2017, In : JAMA Oncology. 3, 6, p. 784-792 9 p.

Research output: Contribution to journalArticle

27 Scopus citations

MST4 Phosphorylation of ATG4B Regulates Autophagic Activity, Tumorigenicity, and Radioresistance in Glioblastoma

Huang, T., Kim, C. K., Alvarez, A. A., Pangeni, R. P., Wan, X., Song, X., Shi, T., Yang, Y., Sastry, N., Horbinski, C. M., Lu, S., Stupp, R., Kessler, J. A., Nishikawa, R., Nakano, I., Sulman, E. P., Lu, X., James, C. D., Yin, X. M., Hu, B. & 1 others, Cheng, S. Y., Dec 11 2017, In : Cancer Cell. 32, 6, p. 840-855.e8

Research output: Contribution to journalArticle

44 Scopus citations

Rindopepimut with temozolomide for patients with newly diagnosed, EGFRvIII-expressing glioblastoma (ACT IV): a randomised, double-blind, international phase 3 trial

Weller, M., Butowski, N., Tran, D. D., Recht, L. D., Lim, M., Hirte, H., Ashby, L., Mechtler, L., Goldlust, S. A., Iwamoto, F., Drappatz, J., O'Rourke, D. M., Wong, M., Hamilton, M. G., Finocchiaro, G., Perry, J., Wick, W., Green, J., He, Y., Turner, C. D. & 32 others, Yellin, M. J., Keler, T., Davis, T. A., Stupp, R., Sampson, J. H., Butowski, N., Campian, J., Recht, L., Lim, M., Ashby, L., Drappatz, J., Hirte, H., Iwamoto, F., Mechtler, L., Goldlust, S., Becker, K., Barnett, G., Nicholas, G., Desjardins, A., Benkers, T., Wagle, N., Groves, M., Kesari, S., Horvath, Z., Merrell, R., Curry, R., O'Rourke, J., Schuster, D., Raizer, J., Lesniak, M., ACT IV trial investigators & ACT IV trial investigators, Oct 2017, In : The Lancet Oncology. 18, 10, p. 1373-1385 13 p.

Research output: Contribution to journalArticle

196 Scopus citations

The Neurologic Assessment in Neuro-Oncology (NANO) scale: A tool to assess neurologic function for integration into the Response Assessment in Neuro-Oncology (RANO) criteria

Nayak, L., Deangelis, L. M., Brandes, A. A., Peereboom, D. M., Galanis, E., Lin, N. U., Soffietti, R., MacDonald, D. R., Chamberlain, M., Perry, J., Jaeckle, K., Mehta, M., Stupp, R., Muzikansky, A., Pentsova, E., Cloughesy, T., Iwamoto, F. M., Tonn, J. C., Vogelbaum, M. A., Wen, P. Y. & 2 others, Van Den Bent, M. J. & Reardon, D. A., May 1 2017, In : Neuro-oncology. 19, 5, p. 625-635 11 p.

Research output: Contribution to journalArticle

25 Scopus citations

Treatment strategies and outcome of surgery for synchronous colorectal liver metastases

Reding, D., Pestalozzi, B. C., Breitenstein, S., Stupp, R., Clavien, P. A., Slankamenac, K. & Samaras, P., Aug 15 2017, In : Swiss Medical Weekly. 147, w14486.

Research output: Contribution to journalArticle

3 Scopus citations
2016

Cilengitide in newly diagnosed glioblastoma: Biomarker expression and outcome

Weller, M., Nabors, L. B., Gorlia, T., Leske, H., Rushing, E., Bady, P., Hicking, C., Perry, J., Hong, Y. K., Roth, P., Wick, W., Goodman, S. L., Hegi, M. E., Picard, M., Moch, H., Straub, J. & Stupp, R., Mar 22 2016, In : Oncotarget. 7, 12, p. 15018-15032 15 p.

Research output: Contribution to journalArticle

26 Scopus citations

Corticosteroids compromise survival in glioblastoma

Pitter, K. L., Tamagno, I., Alikhanyan, K., Hosni-Ahmed, A., Pattwell, S. S., Donnola, S., Dai, C., Ozawa, T., Chang, M., Chan, T. A., Beal, K., Bishop, A. J., Barker, C. A., Jones, T. S., Hentschel, B., Gorlia, T., Schlegel, U., Stupp, R., Weller, M., Holland, E. C. & 1 others, Hambardzumyan, D., May 1 2016, In : Brain. 139, 5, p. 1458-1471 14 p.

Research output: Contribution to journalArticle

95 Scopus citations

Development of OXY111A, a novel hypoxia-modifier as a potential antitumor agent in patients with hepato-pancreato-biliary neoplasms - Protocol of a first Ib/IIa clinical trial

Limani, P., Linecker, M., Kron, P., Samaras, P., Pestalozzi, B., Stupp, R., Jetter, A., Dutkowski, P., Müllhaupt, B., Schlegel, A., Nicolau, C., Lehn, J. M., Petrowsky, H., Humar, B., Graf, R. & Clavien, P. A., Oct 19 2016, In : BMC cancer. 16, 1, 812.

Research output: Contribution to journalArticle

7 Scopus citations

Does valproic acid or levetiracetam improve survival in glioblastoma? A pooled analysis of prospective clinical trials in newly diagnosed glioblastoma

Happold, C., Gorlia, T., Chinot, O., Gilbert, M. R., Nabors, L. B., Wick, W., Pugh, S. L., Hegi, M., Cloughesy, T., Roth, P., Reardon, D. A., Perry, J. R., Mehta, M. P., Stupp, R. & Weller, M., Mar 1 2016, In : Journal of Clinical Oncology. 34, 7, p. 731-739 9 p.

Research output: Contribution to journalArticle

56 Scopus citations

Health-related quality of life in patients with high-risk low-grade glioma (EORTC 22033-26033): a randomised, open-label, phase 3 intergroup study

Reijneveld, J. C., Taphoorn, M. J. B., Coens, C., Bromberg, J. E. C., Mason, W. P., Hoang-Xuan, K., Ryan, G., Hassel, M. B., Enting, R. H., Brandes, A. A., Wick, A., Chinot, O., Reni, M., Kantor, G., Thiessen, B., Klein, M., Verger, E., Borchers, C., Hau, P., Back, M. & 6 others, Smits, A., Golfinopoulos, V., Gorlia, T., Bottomley, A., Stupp, R. & Baumert, B. G., Nov 1 2016, In : The Lancet Oncology. 17, 11, p. 1533-1542 10 p.

Research output: Contribution to journalArticle

45 Scopus citations

Phase II study of radiotherapy and temsirolimus versus radiochemotherapy with temozolomide in patients with newly diagnosed glioblastoma without MGMT promoter hypermethylation (EORTC 26082)

Wick, W., Gorlia, T., Bady, P., Platten, M., Van Den Bent, M. J., Taphoorn, M. J. B., Steuve, J., Brandes, A. A., Hamou, M. F., Wick, A., Kosch, M., Weller, M., Stupp, R., Roth, P., Golfinopoulos, V., Frene, J. S., Campone, M., Ricard, D., Marosi, C., Villa, S. & 6 others, Weyerbrock, A., Hopkins, K., Homicsko, K., Lhermitte, B., Pesce, G. & Hegi, M. E., Oct 1 2016, In : Clinical Cancer Research. 22, 19, p. 4797-4806 10 p.

Research output: Contribution to journalArticle

46 Scopus citations

Preoperative versus postoperative docetaxel-cisplatin- fluorouracil (TCF) chemotherapy in locally advanced resectable gastric carcinoma: 10-year follow-up of the SAKK 43/99 phase III trial

Fazio, N., Biffi, R., Maibach, R., Hayoz, S., Thierstein, S., Brauchli, P., Bernhard, J., Stupp, R., Andreoni, B., Renne, G., Crosta, C., Morant, R., Chiappa, A., Luca, F., Zampino, M. G., Huber, O., Goldhirsch, A., de Braud, F., Roth, A. D., Pace, U. & 15 others, Cenciarelli, S., Pozzi, S., Bertani, E., Mura, S., Lorizzo, K., Di Meglio, G., Ravizza, D., Boselli, S., Matter, M., Richter, M., Monfardini, S., Dittrich, C., Häfner, M., Clemens, M. & Crowe, S., Apr 1 2016, In : Annals of Oncology. 27, 4, p. 668-673 6 p., mdv620.

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12 Scopus citations

PROX1 is a novel pathway-specific prognostic biomarker for high-grade astrocytomas; results from independent glioblastoma cohorts stratified by age and IDH mutation status

Roodakker, K. R., Elsir, T., Edqvist, P. H. D., Hägerstrand, D., Carlson, J., Lysiak, M., Henriksson, R., Pontén, F., Rosell, J., Söderkvist, P., Stupp, R., Tchougounova, E., Nistér, M., Malmström, A. & Smits, A., Jan 1 2016, In : Oncotarget. 7, 45, p. 72431-72442 12 p.

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4 Scopus citations

Temozolomide chemotherapy versus radiotherapy in high-risk low-grade glioma (EORTC 22033-26033): a randomised, open-label, phase 3 intergroup study

Baumert, B. G., Hegi, M. E., van den Bent, M. J., von Deimling, A., Gorlia, T., Hoang-Xuan, K., Brandes, A. A., Kantor, G., Taphoorn, M. J. B., Hassel, M. B., Hartmann, C., Ryan, G., Capper, D., Kros, J. M., Kurscheid, S., Wick, W., Enting, R., Reni, M., Thiessen, B., Dhermain, F. & 17 others, Bromberg, J. E., Feuvret, L., Reijneveld, J. C., Chinot, O., Gijtenbeek, J. M. M., Rossiter, J. P., Dif, N., Balana, C., Bravo-Marques, J., Clement, P. M., Marosi, C., Tzuk-Shina, T., Nordal, R. A., Rees, J., Lacombe, D., Mason, W. P. & Stupp, R., Nov 1 2016, In : The Lancet Oncology. 17, 11, p. 1521-1532 12 p.

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152 Scopus citations