Grants per year
Personal profile
Research Interests
I am an Associate Professor of Surgery in the Division of Cardiac Surgery at Northwestern University and Attending Cardiac Surgeon at Northwestern Medicine. Within the Bluhm Cardiovascular institute, I co-direct the Marfan Clinic, Bicuspid Aortic Valve Clinic and Thoracic Aortic Surgery Program. As Chairman of the Blood Transfusion Committee, I seek to advance patient blood management and responsible blood transfusion practices at Northwestern Memorial Hospital.
My academic focus is clinical research in novel valve therapies including trans-catheter valve repair / replacement and minimally-invasive valve surgery.
My clinical focus is complex cardiac surgery including valve-sparing aortic root replacement, bicuspid aortic valve repair, minimally-invasive valve surgery, aortic arch / thoraco-abdominal aortic surgery, and pulmonary thrombo-endarterectomy.
Certifications and Licenses
| Cardiothoracic Surgery | |
| Surgery |
Training Experience
| 2004 | Residency, Loyola University Medical Center |
| 2006 | Fellowship, Baylor Affiliated Hospitals |
| 2007 | Fellowship, Stanford University Hospital |
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Medicine, MD, University of Maryland
… → 1998
Research interests keywords
- Aortic Aneurysm
- Aortic Valve Replacement
- Cardiovascular Diseases
- Heart Disease
- Heart Transplantation
- Mechanical Circulatory Assistance
- Minimally Invasive Heart Procedures
- Mitral Valve Repair
- Pulmonary Thromboembolism
- Surgery
- Valve Repair/Replacement
- Valvular Disease
Fingerprint
Dive into the research topics where S. Chris Malaisrie is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Prot # ABT-CIP-10487: Evaluation of the Navitor Transcatheter Heart Valve in Low and Intermediate Risk Patients who have Severe, Symptomatic, Aortic Stenosis Requiring Aortic Valve Replacement (ENVISION IDE)
Asgar, A. W. (PD/PI), Malaisrie, S. C. (PD/PI) & Malaisrie, S. C. (Co-Investigator)
St. Jude Medical Business Services, Inc.
1/22/25 → 1/21/28
Project: Research project
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Prot #STU00219165: Mitral Valve Screening Survey (MVSS)
Malaisrie, S. C. (PD/PI)
MedStar Health Research Institute, Medtronic, Inc.
9/21/23 → 9/21/26
Project: Research project
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Prot # EXTEND-001: Thoraflex Hybrid and Relay Extension Post-Approval Study (EXTEND)
Malaisrie, S. C. (PD/PI)
9/11/23 → 9/11/26
Project: Research project
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Bioprosthetic vs Mechanical Aortic Valve Replacement in Patients 40 to 75 Years of Age
Bowdish, M. E., Mehaffey, J. H., Chang, S. C., O'Gara, P. T., Mack, M. J., Goldstone, A. B., Chikwe, J., Gillinov, A. M., Wu, C., Fontana, G. P., Bavaria, J. E., Malaisrie, C. S., Kaneko, T., Sultan, I. S., Wyler von Ballmoos, M. C., Harrington, K. B., Jacobs, J. P., Thourani, V. H., Szeto, W. Y. & Sabik, J. F. & 2 others, , Apr 1 2025, In: Journal of the American College of Cardiology. 85, 12, p. 1289-1298 10 p.Research output: Contribution to journal › Article › peer-review
6 Scopus citations -
Five- Year Outcomes in Low-Risk Patients Undergoing Surgery in the PARTNER 3 Trial
Thourani, V. H., Leon, M. B., Makkar, R., Ascione, G., Szeto, W. Y., Madhavan, M. V., Kodali, S. K., Hahn, R. T., Pibarot, P., Malaisrie, S. C., Kapadia, S. R., Russo, M. J., Herrmann, H. C., Babaliaros, V., Guyton, R., Genereux, P., Cohen, D. J., Park, B., Clarke, S. & Gunnarsson, M. & 7 others, , Mar 2025, In: Annals of Thoracic Surgery. 119, 3, p. 555-566 12 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Outcomes of Multidisciplinary Care at a Chronic Thromboembolic Pulmonary Hypertension Center
Christopher Malaisrie, S., Chiu, S. F., Schimmel, D., Samant, M., Avery, R. J., Rahsepar, A., Allen, B. D., Raza, Y., Freed, B., Mylvaganam, R. & Cuttica, M. J., Apr 2025, In: Pulmonary Circulation. 15, 2, e70085.Research output: Contribution to journal › Article › peer-review
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Overlap and correlation of reperfusion lung injury with postoperative pneumonia following pulmonary thromboendarterectomy: incidence, characteristics, and outcomes in chronic thromboembolic pulmonary hypertension
Rathod, S. N., Ropski, P., Glowala, J., Quinn, C. M., Stamper, A., Bolon, M. K., Schimmel, D., Chiu, S. F., Malaisrie, S. C. C., Cuttica, M. J. & Mylvaganam, R., Dec 2025, In: BMC Pulmonary Medicine. 25, 1, 119.Research output: Contribution to journal › Article › peer-review
Open Access -
Overview of contemporary guidelines for management of acute type A aortic dissection
Mehta, C. K., Medina, M. G., Whippo, B. & Malaisrie, S. C., Jun 2025, In: Journal of Thoracic and Cardiovascular Surgery. 169, 6, p. 1677-1683 7 p.Research output: Contribution to journal › Editorial › peer-review
1 Scopus citations
Datasets
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Supplementary Material 1 - Supplemental material for Contemporary Reoperative Mitral Valve Surgery: Technical Considerations and Clinical Outcomes
Fatehi Hassanabad, A. (Contributor), Turcotte, M. (Creator), Dennehy, C. (Creator), Kim, A. (Creator), Malaisrie, S. C. (Contributor) & Kent, W. D. T. (Creator), SAGE Journals, 2020
DOI: 10.25384/sage.12974007, https://sage.figshare.com/articles/presentation/Supplementary_Material_1_-_Supplemental_material_for_Contemporary_Reoperative_Mitral_Valve_Surgery_Technical_Considerations_and_Clinical_Outcomes/12974007
Dataset
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Relationship of left ventricular outflow tract velocity time integral to treatment strategy in submassive and massive pulmonary embolism
Antoine, D. (Creator), Chuich, T. (Creator), Mylvaganam, R. (Creator), Malaisrie, C. (Creator), Freed, B. (Creator), Cuttica, M. (Creator) & Schimmel, D. (Creator), SAGE Journals, 2020
DOI: 10.25384/sage.c.5136393, https://sage.figshare.com/collections/Relationship_of_left_ventricular_outflow_tract_velocity_time_integral_to_treatment_strategy_in_submassive_and_massive_pulmonary_embolism/5136393
Dataset
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Contemporary Reoperative Mitral Valve Surgery: Technical Considerations and Clinical Outcomes
Fatehi Hassanabad, A. (Contributor), Turcotte, M. (Creator), Dennehy, C. (Creator), Kim, A. (Creator), Malaisrie, S. C. (Contributor) & Kent, W. D. T. (Creator), SAGE Journals, 2020
DOI: 10.25384/sage.c.5126067, https://sage.figshare.com/collections/Contemporary_Reoperative_Mitral_Valve_Surgery_Technical_Considerations_and_Clinical_Outcomes/5126067
Dataset