S. Chris Malaisrie

Grants

Grants per year 2005 2007 2008 2011 2012 2016 2017 2018 2020 2022 2023 2030

• 16 Active
• 28 Finished

Grants per year

Search results

• Active

  Prot #2021-05-AVIV: ALLIANCE AVIV: Safety and Effectiveness of Balloon-Expandable Bioprosthetic SAPIEN X4 Transcatheter Heart Valve in Failing Aortic Bioprosthetic Valves

  Malaisrie, S. C. (PD/PI)

  Edwards Lifesciences LLC

  5/7/24 → 5/7/27

  Project: Research project

• Prot #STU00219165: Mitral Valve Screening Survey (MVSS)

  Malaisrie, S. C. (PD/PI)

  MedStar Health Research Institute, Medtronic, Inc.

  9/21/23 → 9/21/26

  Project: Research project

• Prot # EXTEND-001: Thoraflex Hybrid and Relay Extension Post-Approval Study (EXTEND)

  Malaisrie, S. C. (PD/PI)

  Vascutek Limited

  9/11/23 → 9/11/26

  Project: Research project

• Prot #AMDS2101.000-C (02/21): A ProspEctive, Single ARm, Multi-center Clinical InveStigation to EValuatE the Safety and Effectiveness of AMDS in the TREatment of Acute DeBakey Type I Dissection: PERSEVERE

  Malaisrie, S. C. (PD/PI)

  CryoLife, Inc.

  2/9/23 → 2/9/26

  Project: Research project

• Prot #2021-05: The ALLIANCE Trial: Safety and Effectiveness of Balloon-Expandable Bioprosthetic SAPIEN X4 Transcatheter Heart Valve

  Malaisrie, S. C. (PD/PI)

  Edwards Lifesciences LLC

  10/18/22 → 10/18/25

  Project: Research project

• Prot #HLT 2101: RIVAL - AR EFS: HLT Meridian TAVR Valve System Early Feasibility Study for Aortic Regurgitation

  Davidson, C. J. (PD/PI) & Malaisrie, S. C. (Co-Investigator)

  HLT, Inc.

  8/16/22 → 8/16/25

  Project: Research project

• Prot#CP2021-2: Outcomes of Surgical AF ablation using CryoICE cryoablation system

  McCarthy, P. M. (PD/PI) & Malaisrie, S. C. (Co-PD/PI)

  AtriCure, Inc.

  2/17/22 → 2/17/25

  Project: Research project

• Prot# ABT-CIP-10304: REPAIR-MR: Percutaneous or Surgical Mitral Valve REpair in PAtients with PrImaRy MItral Regurgitation Whose Mitral Valve has been Determined to be Suitable for Correction by MV Repair Surgery

  Davidson, C. J. (PD/PI), Malaisrie, S. C. (Co-Investigator), McCarthy, P. M. (Co-Investigator) & Mutharasan, R. K. (Co-Investigator)

  Evalve, Inc.

  3/12/20 → 3/11/25

  Project: Research project

• Prot#2015-08 MVIV: PARTNER 3 Mitral Valve-in-Valve - A Prospective, Single-Arm, Multicenter Study to Investigate the Safety and Effectiveness of SAPIEN 3 Transcatheter Heart Valve Implantation in Patients with a Failing Mitral Bioprosthetic Valve

  Malaisrie, S. C. (PD/PI)

  Edwards Lifesciences LLC

  5/10/18 → 5/10/27

  Project: Research project

• APOLLO Trial Clinical Investigation Plan - Transcatheter Mitral Valve Replacement with the Medtronic Intrepid™ TMVR System in patients with severe symptomatic mitral regurgitation

  Malaisrie, S. C. (PD/PI) & McCarthy, P. M. (Other)

  Medtronic, Inc.

  1/25/18 → 1/25/28

  Project: Research project

• Prot# IP-0017-16: A Prospective, Multicenter, Non-Blinded, Non-Randomized Study of the RelayPro Thoracic Stent-Graft in Subjects with an Acute, Complicated Type B Aortic Dissection

  Malaisrie, S. C. (PD/PI)

  Bolton Medical, Inc.

  6/16/17 → 6/16/26

  Project: Research project

• P3 AVIV Registry - A Prospective, Single-Arm, Multicenter Study to Investigate the Safety and Effectiveness of SAPIEN 3 Transcatheter Heart Valve Implantation in Patients With a Failing Aortic Bioprosthetic Valve

  Malaisrie, S. C. (PD/PI)

  Edwards Lifesciences Corporation

  5/16/17 → 5/16/27

  Project: Research project

• Evaluation of Transcatheter Aortic Valve Replacement Compared to SurveilLance for Patients with AsYmptomatic Severe Aortic Stenosis: EARLY-TAVR trial

  Malaisrie, S. C. (PD/PI)

  Edwards Lifesciences LLC

  4/4/17 → 4/4/26

  Project: Research project

• Prot#2015-08:PARTNER 3 Trial: A Prospective, Randomized, Controlled, Multi-Center Study to Establish the Safety and Effectiveness of the SAPIEN 3 Transcatheter Heart Valve in Low Risk Patients Requiring Aortic Valve Replacement who have Severe, Calcific,

  Malaisrie, S. C. (PD/PI)

  Edwards Lifesciences LLC

  5/17/16 → 5/17/30

  Project: Research project

• Prot #HYBRID-002: Evaluation of the Thoraflex™ Hybrid Device for Use in the Repair or Replacement of the Ascending Aorta, Aortic Arch and Descending Aorta in an Open Surgical Procedure.

  Malaisrie, S. C. (PD/PI)

  Terumo Cardiovascular Systems Corporation

  5/6/16 → 5/6/25

  Project: Research project

• Prot# 2010-12-US: The PARTNER II Trial: Placement of AoRTic TraNscathetER Valves Trial. Edwards SAPIEN XT Transcatheter Heart Valve.

  Malaisrie, S. C. (PD/PI), McCarthy, P. M. (PD/PI) & Davidson, C. J. (Co-Investigator)

  Edwards Lifesciences Corporation

  4/15/11 → 12/31/25

  Project: Research project

• Finished

  Prot #TCR 20‐02: The SOAR (tranSseptal chOrdAl Repair) Early Feasibility Study of a Transseptal Chordal Repair System for Treatment of Severe Degenerative Mitral Regurgitation

  Malaisrie, S. C. (PD/PI)

  Pipeline Medical Technologies, Inc.

  7/13/23 → 7/13/24

  Project: Research project

• Prot#ONX1801.000-C: A Prospective, Randomized, Active (Warfarin) Controlled, Parallel-Arm Clinical Trial to Determine if Patients with an On-X Aortic Valve can be Maintained Safely and Effectively on the Factor Xa Inhibitor Apixaban (PROACT Xa)

  Malaisrie, S. C. (PD/PI)

  CryoLife, Inc.

  8/10/20 → 8/10/23

  Project: Research project

• 4D Virtual Catheter (vCath) Assessment of Hemodynamic Pathways in Aortopathy Pathogenesis

  Markl, M. (PD/PI), Bonow, R. O. (Co-Investigator), Malaisrie, S. C. (Co-Investigator), Ragin, A. (Co-Investigator) & Elbaz, M. (Other)

  National Heart, Lung, and Blood Institute

  2/1/20 → 1/31/24

  Project: Research project

  • Aortic Valve Disease 100%
  • Catheter 100%
  • Aortopathy 100%
  • Hemodynamic 100%
  • Magnetic Resonance Imaging 40%

• Virtual Catheter (vCath) for Noninvasive Hemodynamics in Bicuspid Aortic Valve

  Markl, M. (PD/PI), Bonow, R. O. (Co-Investigator) & Malaisrie, S. C. (Co-Investigator)

  Northwestern Memorial Hospital

  1/1/19 → 8/31/20

  Project: Research project

  • Invasive Hemodynamics 100%
  • Catheter 100%
  • Bicuspid Aortic Valve 100%
  • Hemodynamic 100%
  • Aortic Flow 42%

• ExCEED - A Prospective, Single-arm, Controlled, Multicenter Study to Establish the Safety and Effectiveness of the CENTERA THV System in Intermediate Risk Patients who have Symptomatic, Severe, Calcific, Aortic Stenosis Requiring Aortic Valve Replacement

  Malaisrie, S. C. (PD/PI)

  Edwards Lifesciences LLC

  11/28/18 → 11/28/21

  Project: Research project

• Functional Cardiovascular 4D MRI in Congenital Heart Disease

  Markl, M. (PD/PI), Barker, A. J. (Co-PD/PI), Bonow, R. O. (Co-PD/PI), Carr, J. (Co-PD/PI), Kim, D. (Co-PD/PI), Malaisrie, S. C. (Co-PD/PI), McCarthy, P. M. (Co-PD/PI), Ragin, A. (Co-PD/PI), Wang, L. (Co-PD/PI) & Elbaz, M. (Co-Investigator)

  National Heart, Lung, and Blood Institute

  4/1/18 → 3/31/24

  Project: Research project

• Prot# PCT1101.011-C: Perclot IDE - Prospective, Multicenter, Multidisciplinary, Controlled Clinical Investigation Evaluating the Safety and Efficacy of PerClot® Polysaccharide Hemostatic System

  Malaisrie, S. C. (PD/PI)

  CryoLife, Inc.

  11/2/17 → 11/2/20

  Project: Research project

• Role of Valve-Mediated Hemodynamics on Bicuspid Aortopathy

  Barker, A. J. (PD/PI), Andrei, A.-C. (Co-Investigator), Bonow, R. O. (Co-Investigator), Collins, J. D. (Co-Investigator), Malaisrie, S. C. (Co-Investigator), Markl, M. (Co-Investigator), McCarthy, P. M. (Co-Investigator) & Puthumana, J. J. (Co-Investigator)

  National Heart, Lung, and Blood Institute

  5/1/17 → 5/30/18

  Project: Research project

  • Bicuspid Aortopathy 100%
  • Bicuspid Aortic Valve 100%
  • Aortopathy 100%
  • Hemodynamic 100%
  • Blood Flow 50%

• Functional Cardiovascular 4D MRI in Congenital Heart Disease

  Markl, M. (PD/PI), Bonow, R. O. (Co-PD/PI), Carr, J. (Co-PD/PI), Malaisrie, S. C. (Co-PD/PI), McCarthy, P. M. (Co-PD/PI) & Ragin, A. (Co-PD/PI)

  National Heart, Lung, and Blood Institute

  7/1/16 → 3/31/18

  Project: Research project