If you made any changes in Pure, your changes will be visible here soon.

Personal profile

Research Interests

Impaired locomotor performance is caused by complex, multi-faceted problems where changes in the nervous, muscular, and skeletal systems are all integrated and dependent on one another in a way that makes diagnosis and interventions difficult to access and implement. Specifically, muscle properties such as musculoskeletal architecture (e.g. muscle fascicle length, pennation angle, muscle thickness, and moment arm), fiber composition, and material properties, as well as motor unit recruitment have been shown to influence locomotor performance in animals, but the relationship between those variables are not well established for many human movements. Populations of great interest to me are individuals with neurological impairments such as cerebral palsy (CP), spinal cord injury (SCI), and stroke. Using a variety of techniques such as ultrasound imaging, magnetic resonance imaging, modeling, histochemistry, electromyography (EMG), wavelet analysis, and gait analysis, I aim to investigate the fundamental mechanisms of neuromuscular muscle function in these populations. This will form the basis for proposing clinical tools used to aid in injury prevention and mobility loss in older adults and to aid in diagnosing and implementing interventions for individuals with CP, stroke, and SCI.

Education/Academic qualification

PhD, Pennsylvania State University

… → 2009

Research interests

  • Cerebral Palsy
  • Electrophysiology
  • Movement Disorders
  • Musculoskeletal Ultrasound
  • Neuromuscular Disorders
  • Physiology
  • Rehabilitation/Therapy
  • Stroke

Fingerprint Dive into the research topics where Sabrina Sien Man Lee is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 27 Similar Profiles
Muscles Medicine & Life Sciences
Muscle Engineering & Materials Science
Shear waves Engineering & Materials Science
Stroke Medicine & Life Sciences
Skeletal Muscle Medicine & Life Sciences
Elasticity Imaging Techniques Medicine & Life Sciences
Tendons Medicine & Life Sciences
Mechanics Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Grants 2016 2022

Muscles
Elasticity Imaging Techniques
Cats
Joints
Wounds and Injuries

Research Output 2008 2019

  • 411 Citations
  • 18 Article
  • 4 Conference contribution
  • 1 Letter
  • 1 Review article

Changes in shear wave propagation within skeletal muscle during active and passive force generation

Wang, A. B., Perreault, E., Royston, T. J. & Lee, S. S. M., Sep 20 2019, In : Journal of Biomechanics. 94, p. 115-122 8 p.

Research output: Contribution to journalArticle

Shear waves
Wave propagation
Muscle
Skeletal Muscle
Muscles
1 Citation (Scopus)

Muscle material properties in passive and active stroke-impaired muscle

Lee, S. S. M., Jakubowski, K. L., Spear, S. C. & Rymer, W. Z., Jan 23 2019, In : Journal of Biomechanics. 83, p. 197-204 8 p.

Research output: Contribution to journalArticle

Muscle
Materials properties
Stroke
Shear waves
Muscles

Response to Letter to the Editor for Manuscript “Muscle material properties in passive and active stroke-impaired muscle”

Lee, S. S. M., Jakubowski, K. L., Spear, S. C. & Rymer, W. Z., Aug 27 2019, In : Journal of Biomechanics. 93, 1 p.

Research output: Contribution to journalLetter

Manuscripts
Muscle
Materials properties
Stroke
Muscles

Frequency Dependence of Shear Wave Velocity in Stroke-Affected Muscles during Isometric Contraction- Preliminary Data

Saadat, F., Son, J., Rymer, W. Z. & Lee, S. S. M., Oct 26 2018, 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2018. Institute of Electrical and Electronics Engineers Inc., p. 2292-2295 4 p. 8512857. (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS; vol. 2018-July).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Isometric Contraction
Shear waves
Muscle
Stroke
Muscles
1 Citation (Scopus)

In vivo relationship between joint stiffness, joint-based estimates of muscle stiffness, and shear-wave velocity

Vigotsky, A. D., Rouse, E. J. & Lee, S. S. M., Oct 26 2018, 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2018. Institute of Electrical and Electronics Engineers Inc., p. 1468-1471 4 p. 8512484. (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS; vol. 2018-July).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Shear waves
Muscle
Joints
Stiffness
Muscles