• 363 Citations
20082022
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Personal profile

Research Interests

Impaired locomotor performance is caused by complex, multi-faceted problems where changes in the nervous, muscular, and skeletal systems are all integrated and dependent on one another in a way that makes diagnosis and interventions difficult to access and implement. Specifically, muscle properties such as musculoskeletal architecture (e.g. muscle fascicle length, pennation angle, muscle thickness, and moment arm), fiber composition, and material properties, as well as motor unit recruitment have been shown to influence locomotor performance in animals, but the relationship between those variables are not well established for many human movements. Populations of great interest to me are individuals with neurological impairments such as cerebral palsy (CP), spinal cord injury (SCI), and stroke. Using a variety of techniques such as ultrasound imaging, magnetic resonance imaging, modeling, histochemistry, electromyography (EMG), wavelet analysis, and gait analysis, I aim to investigate the fundamental mechanisms of neuromuscular muscle function in these populations. This will form the basis for proposing clinical tools used to aid in injury prevention and mobility loss in older adults and to aid in diagnosing and implementing interventions for individuals with CP, stroke, and SCI.

Education/Academic qualification

PhD, Pennsylvania State University

… → 2009

Keywords

  • Cerebral Palsy
  • Electrophysiology
  • Movement Disorders
  • Musculoskeletal Ultrasound
  • Neuromuscular Disorders
  • Physiology
  • Rehabilitation/Therapy
  • Stroke

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Grants 2016 2022

Muscles
Elasticity Imaging Techniques
Cats
Joints
Wounds and Injuries

Research Output 2008 2019

  • 363 Citations
  • 17 Article
  • 2 Conference contribution
  • 1 Review article

Muscle material properties in passive and active stroke-impaired muscle

Lee, S. S. M., Jakubowski, K. L., Spear, S. C. & Rymer, W. Z., Jan 23 2019, In : Journal of Biomechanics. 83, p. 197-204 8 p.

Research output: Contribution to journalArticle

Muscle
Materials properties
Stroke
Shear waves
Muscles

Shear Waves Reveal Viscoelastic Changes in Skeletal Muscles after Hemispheric Stroke

Rasool, G., Wang, A. B., Rymer, W. Z. & Lee, S. S. M., Oct 1 2018, In : IEEE Transactions on Neural Systems and Rehabilitation Engineering. 26, 10, p. 2006-2014 9 p., 8466608.

Research output: Contribution to journalArticle

Shear waves
Muscle
Skeletal Muscle
Stroke
Muscles

The relationship between volitional activation and muscle properties in incomplete spinal cord injury

Jakubowski, K. L., Smith, A. C., Elliott, J. M. & Lee, S. S. M., Jan 1 2018, In : Topics in spinal cord injury rehabilitation. 24, 1, p. 1-5 5 p.

Research output: Contribution to journalArticle

Spinal Cord Injuries
Muscles
Torque
Therapeutics
2 Citations (Scopus)

Passive material properties of stroke-impaired plantarflexor and dorsiflexor muscles

Jakubowski, K. L., Terman, A., Santana, R. V. C. & Lee, S. S. M., Nov 1 2017, In : Clinical Biomechanics. 49, p. 48-55 8 p.

Research output: Contribution to journalArticle

Stroke
Muscles
Elasticity Imaging Techniques
Joints
Torque
9 Citations (Scopus)

Skeletal muscle mechanics, energetics and plasticity Daniel P Ferris

Lieber, R. L., Roberts, T. J., Blemker, S. S., Lee, S. S. M. & Herzog, W., Oct 23 2017, In : Journal of neuroengineering and rehabilitation. 14, 1, 108.

Research output: Contribution to journalReview article

Mechanics
Skeletal Muscle
Muscles
Sarcomeres
Muscle Spasticity