• Source: Scopus

Research activity per year

If you made any changes in Pure these will be visible here soon.

Personal profile

Research Interests

It is estimated that 10-25% of human embryos are chromosomally abnormal, resulting in a high incidence of miscarriages and birth defects. Most of these abnormalities are the result of chromosome segregation defects in the female reproductive cells (oocytes), yet surprisingly little is known about the biological mechanisms that underlie the vulnerability of oocytes to segregation errors.  The Wignall lab is focused on investigating this important problem, by combining high-resolution microscopy with genetic, genomic, and biochemical approaches in the nematode C. elegans.  Current work in the lab is focused on two major areas:  1) investigating the molecular mechanisms of spindle assembly in oocytes, and 2) exploring mechanisms of chromosome congression and segregation.

Education/Academic qualification

Molecular and Cell Biology, PhD, University of California at Berkeley

… → 2003

Biological Sciences, MPhil, University of Cambridge

… → 1997

Biology, BS, University of North Carolina at Chapel Hill

… → 1996


Dive into the research topics where Sadie Wignall is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
  • 1 Similar Profiles


Recent external collaboration on country/territory level. Dive into details by clicking on the dots or