Grants per year
Personal profile
Research Interests
Dr. Khan is board certified in Internal Medicine and Cardiovascular Diseases and holds active medical licensure in the state of Illinois. She received her medical degree from the Feinberg School of Medicine at Northwestern University in 2009 as part of the Honors Program in Medical Education. She completed her internship and residency in Internal Medicine at Northwestern University Feinberg School of Medicine in Chicago, IL in 2012 and then served as Chief Medical Resident from 2012-2013. She also obtained her master’s degree in Clinical Investigation from the Northwestern University Graduate School in 2014. Dr. Khan completed her fellowship in cardiovascular diseases at Northwestern in 2016 followed by a post-doctoral fellowship in cardiovascular epidemiology in 2017 before joining the Northwestern faculty. She has received multiple awards for excellence in research, teaching, and patient care.
My laboratory examines the influence of obesity on development of cardiovascular diseases. Our studies include population-based cohorts, large electronic health record data analysis, and -OMICS (epigenomics, genomics, and proteomics) to perform mechanistic studies to enhance cardiovascular risk prediction and identify novel therapeutic agents for prevention and treatment approaches. As a practicing cardiologist, I see patients at-risk for and with cardiovascular disease. I am trained in cardiovascular and molecular epidemiology and cardiovascular genetics. I am committed to translating research into clinical practice through use of implementation science principles to improve cardiovascular outcomes and care on an individual-level and population-level.
I see patients with a variety of cardiovascular diseases and to discuss preventive strategies prior to the development of cardiovascular diseases with a particular focus among patients with heart failure with preserved ejection fraction (HFpEF). I am also interested in practicing precision or personalized medicine with a particular focus on the utility of genetic testing and risk communication with patients who are at-risk for cardiomyopathy, arrhythmia, and vascular disorders (e.g. aortic aneurysm). As a staff cardiologist at Northwestern Memorial Hospital and member of the Bluhm Cardiovascular Center, I serve on the inpatient cardiology consult service and conduct weekly ambulatory clinic sessions.
Training Experience
2010 | Internship, Northwestern University, McGaw Medical Center |
2012 | Residency, Northwestern University, McGaw Medical Center |
2016 | Fellowship, Northwestern University, McGaw Medical Center |
2017 | Postdoctoral Fellowship, Northwestern University |
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
MSc, Clinical Investigation, Northwestern University
… → 2014
Medicine, MD, Northwestern University Feinberg School of Medicine
… → 2009
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Collaborations and top research areas from the last five years
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REACH BP: The Remotely Evaluating Cardiovascular Health in Birthing People Cohort Study
Cameron, N. A. (PD/PI), Cameron, K. A. (Other), Carnethon, M. R. (Other), Khan, S. S. (Other), Persell, S. D. (Other), Phillips, S. M. (Other), Welty, L. J. (Other) & Yee, L. M. (Other)
4/1/25 → 3/31/28
Project: Research project
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Element B + Subcontracts
Becker, S. (PD/PI), D'Aquila, R. T. (PD/PI), Yancy, C. W. (PD/PI), Alshurafa, N. (Other), Ameer, G. A. (Other), Beidas, R. S. (Other), Blanco, I. (Other), Bradley, C. D. (Other), Brawley, C. (Other), Brown, O. E. (Other), Brown, C. H. (Other), Cameron, K. A. (Other), Carnethon, M. R. (Other), Cooper, L. A. D. (Other), Feinstein, M. J. (Other), Franklin, P. D. (Other), Helseth, S. A. (Other), Hill, V. B. (Other), Holmes, K. (Other), Kalhan, R. (Other), Khan, S. S. (Other), Kho, A. N. (Other), Li, D. H. (Other), Liebovitz, D. M. (Other), Luo, Y. (Other), Macapagal, K. (Other), O'Brien, M. J. (Other), Passman, R. S. (Other), Perreault, E. (Other), Peters, A. T. (Other), Pickens, C. I. (Other), Rasmussen-Torvik, L. J. (Other), Rivnay, J. (Other), Rosenberg, S. R. (Other), Schauer, J. M. (Other), Scott, K. (Other), Scott, E. A. (Other), Simon, M. A. (Other), Skolarus, L. E. (Other), Spring, B. (Other), Starren, J. (Other), Tandon, D. (Other), Walunas, T. L. (Other), Welty, L. J. (Other), Woitowich, N. C. (Other) & Wolf, M. (Other)
National Center for Advancing Translational Sciences
9/1/24 → 7/31/31
Project: Research project
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2-Generation Interventions to Improve Cardiovascular Health in Indiana and Illinois Through Home Visiting (2-NOURISH)
Khan, S. S. (PD/PI), Tandon, D. (PD/PI), Khan, S. S. (Co-PD/PI), Carroll, A. J. (Co-Investigator), Muhammad, L. N. (Co-Investigator), O'Brien, M. J. (Co-Investigator), Van Horn, L. (Co-Investigator) & Yee, L. M. (Co-Investigator)
National Heart, Lung, and Blood Institute
7/1/24 → 6/30/29
Project: Research project
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Reducing the risk of chronic hypertension and improving vascular function following
Yee, L. M. (PD/PI) & Khan, S. S. (Co-Investigator)
Medical College of Wisconsin, National Institute of Child Health and Human Development
7/1/24 → 6/30/25
Project: Research project
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Role of dynamic stressors in inflammation and early HFpEF risk
Feinstein, M. J. (PD/PI), Kershaw, K. N. (PD/PI), Kershaw, K. N. (Co-PD/PI), Alexandria, S. J. (Co-Investigator), Khan, S. S. (Co-Investigator) & Patel, R. B. (Co-Investigator)
4/1/24 → 3/31/28
Project: Research project
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Association of neighborhood-level socioeconomic disadvantage and Life's Essential 8 in early pregnancy
Venkatesh, K. K., Grobman, W. A., Huang, X., Yee, L. M., Catov, J., Simhan, H., Haas, D. M., Mercer, B., Reddy, U., Silver, R. M., Levine, L. D., Chung, J., Saade, G., Greenland, P., Bairey Merz, C. N., McNeil, B. & Khan, S. S., Mar 2025, In: American Journal of Preventive Cardiology. 21, 100925.Research output: Contribution to journal › Article › peer-review
Open Access -
Associations between life-course FEV1/FVC trajectories and respiratory symptoms up to middle age: analysis of data from two prospective cohort studies
AUSCULTATE investigator group, Feb 2025, In: The Lancet Respiratory Medicine. 13, 2, p. 130-140 11 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Blood Pressure in Pregnancy and Hypertension 10-14 Years after Delivery
Venkatesh, K. K., Grobman, W. A., Wu, J., Costantine, M. M., Landon, M. B., Scholtens, D., Lowe, W., Shah, N. S., Cameron, N. A. & Khan, S. S., Feb 1 2025, In: Obstetrics and gynecology. 145, 2, p. 217-219 3 p.Research output: Contribution to journal › Article › peer-review
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Cardiac CT Calcium Score
Glynn, P., Khan, S. S. & Greenland, P., 2025, (Accepted/In press) In: JAMA.Research output: Contribution to journal › Review article › peer-review
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Cardiovascular Disease Mortality Trends, 2010–2022: An Update with Final Data
Woodruff, R. C., Tong, X., Loustalot, F. V., Khan, S. S., Shah, N. S., Jackson, S. L. & Vaughan, A. S., Feb 2025, In: American Journal of Preventive Medicine. 68, 2, p. 391-395 5 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations
Datasets
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Association of cardiovascular health and epigenetic age acceleration
Pottinger, T. D. (Creator), Khan, S. S. (Creator), Zheng, Y. (Creator), Zhang, W. (Creator), Tindle, H. A. (Creator), Allison, M. (Creator), Wells, G. (Creator), Shadyab, A. H. (Creator), Nassir, R. (Creator), Martin, L. W. (Creator), Manson, J. E. (Creator), Lloyd-Jones, D. M. (Creator), Greenland, P. (Creator), Baccarelli, A. A. (Creator), Whitsel, E. A. (Creator) & Hou, L. (Creator), figshare, 2021
DOI: 10.6084/m9.figshare.c.5319491.v1, https://springernature.figshare.com/collections/Association_of_cardiovascular_health_and_epigenetic_age_acceleration/5319491/1
Dataset
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Association between county-level risk groups and COVID-19 outcomes in the United States: a socioecological study
Khan, S. S. (Creator), Krefman, A. E. (Creator), McCabe, M. E. (Creator), Petito, L. C. (Creator), Yang, X. (Creator), Kershaw, K. N. (Creator), Pool, L. R. (Creator) & Allen, N. B. (Creator), figshare, 2022
DOI: 10.6084/m9.figshare.c.5792940.v1, https://springernature.figshare.com/collections/Association_between_county-level_risk_groups_and_COVID-19_outcomes_in_the_United_States_a_socioecological_study/5792940/1
Dataset
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Association of fasting glucose with lifetime risk of incident heart failure: the Lifetime Risk Pooling Project
Sinha, A. (Creator), Ning, H. (Contributor), Ahmad, F. S. (Contributor), Bancks, M. P. (Creator), Carnethon, M. R. (Creator), O’Brien, M. J. (Creator), Allen, N. B. (Contributor), Wilkins, J. T. (Creator), Lloyd-Jones, D. M. (Creator) & Khan, S. S. (Creator), figshare, 2021
DOI: 10.6084/m9.figshare.c.5348887, https://springernature.figshare.com/collections/Association_of_fasting_glucose_with_lifetime_risk_of_incident_heart_failure_the_Lifetime_Risk_Pooling_Project/5348887
Dataset
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Epigenetic age acceleration and metabolic syndrome in the coronary artery risk development in young adults study
Nannini, D. R. (Creator), Joyce, B. T. (Creator), Zheng, Y. (Creator), Gao, T. (Creator), Liu, L. (Creator), Yoon, G. (Creator), Huan, T. (Creator), Ma, J. (Creator), Jacobs, D. R. (Creator), Wilkins, J. T. (Creator), Ren, J. (Creator), Zhang, K. (Creator), Khan, S. S. (Creator), Allen, N. B. (Creator), Horvath, S. (Creator), Lloyd-Jones, D. M. (Creator), Greenland, P. (Creator) & Hou, L. (Creator), figshare, 2019
DOI: 10.6084/m9.figshare.c.4741883, https://springernature.figshare.com/collections/Epigenetic_age_acceleration_and_metabolic_syndrome_in_the_coronary_artery_risk_development_in_young_adults_study/4741883
Dataset