Grants per year
Personal profile
Research Interests
Dr. Khan is board certified in Internal Medicine and Cardiovascular Diseases and holds active medical licensure in the state of Illinois. She received her medical degree from the Feinberg School of Medicine at Northwestern University in 2009 as part of the Honors Program in Medical Education. She completed her internship and residency in Internal Medicine at Northwestern University Feinberg School of Medicine in Chicago, IL in 2012 and then served as Chief Medical Resident from 2012-2013. She also obtained her master’s degree in Clinical Investigation from the Northwestern University Graduate School in 2014. Dr. Khan completed her fellowship in cardiovascular diseases at Northwestern in 2016 followed by a post-doctoral fellowship in cardiovascular epidemiology in 2017 before joining the Northwestern faculty. She has received multiple awards for excellence in research, teaching, and patient care.
My laboratory examines the influence of obesity on development of cardiovascular diseases. Our studies include population-based cohorts, large electronic health record data analysis, and -OMICS (epigenomics, genomics, and proteomics) to perform mechanistic studies to enhance cardiovascular risk prediction and identify novel therapeutic agents for prevention and treatment approaches. As a practicing cardiologist, I see patients at-risk for and with cardiovascular disease. I am trained in cardiovascular and molecular epidemiology and cardiovascular genetics. I am committed to translating research into clinical practice through use of implementation science principles to improve cardiovascular outcomes and care on an individual-level and population-level.
I see patients with a variety of cardiovascular diseases and to discuss preventive strategies prior to the development of cardiovascular diseases with a particular focus among patients with heart failure with preserved ejection fraction (HFpEF). I am also interested in practicing precision or personalized medicine with a particular focus on the utility of genetic testing and risk communication with patients who are at-risk for cardiomyopathy, arrhythmia, and vascular disorders (e.g. aortic aneurysm). As a staff cardiologist at Northwestern Memorial Hospital and member of the Bluhm Cardiovascular Center, I serve on the inpatient cardiology consult service and conduct weekly ambulatory clinic sessions.
Training Experience
2010 | Internship, Northwestern University, McGaw Medical Center |
2012 | Residency, Northwestern University, McGaw Medical Center |
2016 | Fellowship, Northwestern University, McGaw Medical Center |
2017 | Postdoctoral Fellowship, Northwestern University |
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
MSc, Clinical Investigation, Northwestern University
… → 2014
Medicine, MD, Northwestern University
… → 2009
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Collaborations and top research areas from the last five years
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Risk-Based Primary Prevention of Heart Failure
Khan, S. S., Lloyd-Jones, D. M., Luo, Y., Petito, L. C. & Welty, L. J.
National Heart, Lung, and Blood Institute
9/1/22 → 8/31/24
Project: Research project
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A double-blind randomized controlled trial to assess the effectiveness and tolerability of a quadruple ultra-low-dose treatment for hypertension (QUARTET)
Ciolino, J. D., Kandula, N. R., Khan, S. S., Lloyd-Jones, D. M. & Paparello, J. J.
Washington University St. Louis, National Heart, Lung, and Blood Institute
8/9/22 → 7/31/24
Project: Research project
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A community-engaged approach to understanding the impact of structural racism on maternal health equity.
Kershaw, K. N., Alexandria, S. J., Khan, S. S. & Simon, M. A.
7/1/22 → 6/30/26
Project: Research project
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2-Generation Interventions to Improve Cardiovascular Health in Indiana and Illinois Through Home Visiting (2-NOURISH)
Khan, S. S., Tandon, D., Brown, C. H., Carroll, A. J., Muhammad, L. N., O'Brien, M. J., Van Horn, L. & Yee, L. M.
National Heart, Lung, and Blood Institute
5/16/22 → 4/30/24
Project: Research project
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2023 ACC/AHA/SCAI advanced training statement on interventional cardiology (coronary, peripheral vascular, and structural heart interventions): A report of the ACC Competency Management Committee
ACC Competency Management Committee, Sep 2023, In: Journal of Thoracic and Cardiovascular Surgery. 166, 3, p. e73-e123Research output: Contribution to journal › Article › peer-review
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Association Between End-Stage Liver Disease and Incident Heart Failure in an Integrated Health System
Chuzi, S., Tanaka, Y., Bavishi, A., Bruce, M., Van Wagner, L. B., Wilcox, J. E., Ahmad, F. S., Ladner, D. P., Lagu, T. & Khan, S. S., Aug 2023, In: Journal of general internal medicine. 38, 11, p. 2445-2452 8 p.Research output: Contribution to journal › Article › peer-review
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Association between gender social norms and cardiovascular disease mortality and life expectancy: an ecological study
Lyell, I., Khan, S. S., Limmer, M., O'Flaherty, M. & Head, A., Apr 27 2023, In: BMJ open. 13, 4, e065486.Research output: Contribution to journal › Article › peer-review
Open Access -
Association of a large-for-gestational-age infant and maternal prediabetes mellitus and diabetes mellitus 10 to 14 years after delivery in the Hyperglycemia and Adverse Pregnancy Outcome Follow-up Study
Venkatesh, K. K., Grobman, W. A., Wu, J., Catalano, P., Landon, M., Scholtens, D., Lowe, W. L. & Khan, S. S., Jun 2023, In: American journal of obstetrics and gynecology. 228, 6, p. 756-758.e3Research output: Contribution to journal › Letter › peer-review
Open Access1 Scopus citations -
Association of Depression and Poor Mental Health With Cardiovascular Disease and Suboptimal Cardiovascular Health Among Young Adults in the United States
Kwapong, Y. A., Boakye, E., Khan, S. S., Honigberg, M. C., Martin, S. S., Oyeka, C. P., Hays, A. G., Natarajan, P., Mamas, M. A., Blumenthal, R. S., Blaha, M. J. & Sharma, G., Feb 7 2023, In: Journal of the American Heart Association. 12, 3, e028332.Research output: Contribution to journal › Article › peer-review
Open Access
Datasets
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Epigenetic age acceleration and metabolic syndrome in the coronary artery risk development in young adults study
Nannini, D. R. (Creator), Joyce, B. (Creator), Zheng, Y. (Contributor), Gao, T. (Creator), Liu, L. (Creator), Yoon, G. (Creator), Huan, T. (Contributor), Ma, J. (Contributor), Jacobs, D. R. (Creator), Wilkins, J. T. (Creator), Ren, J. (Creator), Zhang, K. (Creator), Khan, S. S. (Creator), Allen, N. B. (Contributor), Horvath, S. (Creator), Lloyd-Jones, D. M. (Creator), Greenland, P. (Creator) & Hou, L. (Contributor), figshare, 2019
DOI: 10.6084/m9.figshare.c.4741883.v1, https://springernature.figshare.com/collections/Epigenetic_age_acceleration_and_metabolic_syndrome_in_the_coronary_artery_risk_development_in_young_adults_study/4741883/1
Dataset
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Association of cardiovascular health and epigenetic age acceleration
Pottinger, T. D. (Creator), Khan, S. S. (Creator), Zheng, Y. (Contributor), Zhang, W. (Creator), Tindle, H. A. (Creator), Allison, M. (Creator), Wells, G. (Creator), Shadyab, A. H. (Creator), Nassir, R. (Creator), Martin, L. W. (Creator), Manson, J. E. (Creator), Lloyd-Jones, D. M. (Creator), Greenland, P. (Creator), Baccarelli, A. A. (Creator), Whitsel, E. A. (Creator), Hou, L. (Contributor), Manson, J. E. (Creator), Lloyd-Jones, D. M. (Creator) & Baccarelli, A. A. (Creator), figshare, 2021
DOI: 10.6084/m9.figshare.c.5319491.v1, https://springernature.figshare.com/collections/Association_of_cardiovascular_health_and_epigenetic_age_acceleration/5319491/1 and one more link, https://springernature.figshare.com/collections/Association_of_cardiovascular_health_and_epigenetic_age_acceleration/5319491 (show fewer)
Dataset
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Association between county-level risk groups and COVID-19 outcomes in the United States: a socioecological study
Khan, S. S. (Creator), Krefman, A. E. (Creator), McCabe, M. E. (Creator), Petito, L. C. (Creator), Yang, X. (Creator), Kershaw, K. N. (Creator), Pool, L. R. (Creator) & Allen, N. B. (Creator), figshare, 2022
DOI: 10.6084/m9.figshare.c.5792940.v1, https://springernature.figshare.com/collections/Association_between_county-level_risk_groups_and_COVID-19_outcomes_in_the_United_States_a_socioecological_study/5792940/1 and one more link, https://springernature.figshare.com/collections/Association_between_county-level_risk_groups_and_COVID-19_outcomes_in_the_United_States_a_socioecological_study/5792940 (show fewer)
Dataset
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Association of fasting glucose with lifetime risk of incident heart failure: the Lifetime Risk Pooling Project
Sinha, A. (Creator), Ning, H. (Contributor), Ahmad, F. S. (Contributor), Bancks, M. P. (Creator), Carnethon, M. R. (Creator), O'Brien, M. J. (Creator), Allen, N. B. (Contributor), Wilkins, J. T. (Creator), Lloyd-Jones, D. M. (Creator), Khan, S. S. (Creator) & Lloyd-Jones, D. M. (Creator), figshare, 2021
DOI: 10.6084/m9.figshare.c.5348887.v1, https://springernature.figshare.com/collections/Association_of_fasting_glucose_with_lifetime_risk_of_incident_heart_failure_the_Lifetime_Risk_Pooling_Project/5348887/1
Dataset