Grants per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Organic Chemistry, PhD, Jadavpur University
… → 2007
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Dive into the research topics where Saktimayee Mitra Roy is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Grants
- 1 Finished
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Preclinical development of a selective attenuator of neuroinflammation for MCI/AD
Watterson, D. M. (PD/PI) & Roy, S. M. (Other)
University of Kentucky, National Institute on Aging
9/1/15 → 4/30/19
Project: Research project
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Optimized 5-HT2b inhibitors for neuropsychiatric syndromes with cognitive dysfunction
Roy, S. M., Acquarone, E., Argyrousi, E. K., Zhang, H., Staniszewski, A., Inoue, A., Ziarek, J. J., Arancio, O. & Watterson, D. M., Jan 1 2025, In: Alzheimer's and Dementia: Translational Research and Clinical Interventions. 11, 1, e70073.Research output: Contribution to journal › Article › peer-review
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A small molecule p38α MAPK inhibitor, MW150, attenuates behavioral deficits and neuronal dysfunction in a mouse model of mixed amyloid and vascular pathologies
Frazier, H. N., Braun, D. J., Bailey, C. S., Coleman, M. J., Davis, V. A., Dundon, S. R., McLouth, C. J., Muzyk, H. C., Powell, D. K., Rogers, C. B., Roy, S. M. & Van Eldik, L. J., Oct 2024, In: Brain, Behavior, and Immunity - Health. 40, 100826.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
The 5HT2b Receptor in Alzheimer's Disease: Increased Levels in Patient Brains and Antagonist Attenuation of Amyloid and Tau Induced Dysfunction
Acquarone, E., Argyrousi, E. K., Arancio, O., Watterson, D. M. & Roy, S. M., Apr 16 2024, In: Journal of Alzheimer's Disease. 98, 4, p. 1349-1360 12 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Therapeutic treatment with the antiinflammatory drug candidate MW151 may partially reduce memory impairment and normalizes hippocampal metabolic markers in a mouse model of comorbid amyloid and vascular pathology
Braun, D. J., Powell, D. K., McLouth, C. J., Roy, S. M., Watterson, D. M. & Van Eldik, L. J., Jan 2022, In: PloS one. 17, 1 January, e0262474.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
First-in-Human Studies of MW01-6-189WH, a Brain-Penetrant, Antineuroinflammatory Small-Molecule Drug Candidate: Phase 1 Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic Studies in Healthy Adult Volunteers
Van Eldik, L. J., Sawaki, L., Bowen, K., Laskowitz, D. T., Noveck, R. J., Hauser, B., Jordan, L., Spears, T. G., Wu, H., Watt, K., Raja, S., Roy, S. M., Watterson, D. M. & Guptill, J. T., Feb 2021, In: Clinical Pharmacology in Drug Development. 10, 2, p. 131-143 13 p.Research output: Contribution to journal › Article › peer-review
9 Scopus citations
Datasets
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CCDC 1851509: Experimental Crystal Structure Determination
Roy, S. M. (Contributor), Watterson, D. M. (Contributor) & Malliakas, C. (Contributor), Cambridge Crystallographic Data Centre, 2018
DOI: 10.5517/ccdc.csd.cc204n3y, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc204n3y&sid=DataCite
Dataset
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Human P38 alpha MAPK In Complex With a Novel and Selective Small Molecule Inhibitor
Watterson, D. M. (Contributor), Grum-Tokars, V. L. (Contributor), Roy, S. M. (Contributor), Schavocky, J. P. (Contributor), de Bradaric, B. (Contributor), Bachstetter, A. D. (Contributor), Xing, B. (Contributor), Dimayuga, E. (Contributor), Saeed, F. (Contributor), Zhang, H. (Contributor), Staniszewski, A. (Contributor), Pelletier, J. C. (Contributor), Minasov, G. (Contributor), Anderson, W. F. (Contributor), Arancio, O. (Contributor) & van Eldik, L. J. (Contributor), Protein Data Bank (PDB), Jun 5 2013
DOI: 10.2210/pdb4F9Y/pdb, https://www.wwpdb.org/pdb?id=pdb_00004f9y
Dataset
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Additional file 1: Table S1. of Retention of normal glia function by an isoform-selective protein kinase inhibitor drug candidate that modulates cytokine production and cognitive outcomes
Zhou, Z. (Contributor), Bachstetter, A. D. (Creator), Späni, C. B. (Creator), Roy, S. M. (Contributor), Watterson, D. M. (Contributor) & Van Eldik, L. J. (Contributor), figshare, 2017
DOI: 10.6084/m9.figshare.c.3735430_d1, https://springernature.figshare.com/articles/dataset/Additional_file_1_Table_S1_of_Retention_of_normal_glia_function_by_an_isoform-selective_protein_kinase_inhibitor_drug_candidate_that_modulates_cytokine_production_and_cognitive_outcomes/4822489
Dataset
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Additional file 4: Table S4. of Retention of normal glia function by an isoform-selective protein kinase inhibitor drug candidate that modulates cytokine production and cognitive outcomes
Zhou, Z. (Contributor), Bachstetter, A. D. (Creator), Späni, C. B. (Creator), Roy, S. M. (Contributor), Watterson, D. M. (Contributor) & Van Eldik, L. J. (Contributor), figshare, 2017
DOI: 10.6084/m9.figshare.c.3735430_d4.v1, https://springernature.figshare.com/articles/dataset/Additional_file_4_Table_S4_of_Retention_of_normal_glia_function_by_an_isoform-selective_protein_kinase_inhibitor_drug_candidate_that_modulates_cytokine_production_and_cognitive_outcomes/4822558/1
Dataset
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CCDC 1851508: Experimental Crystal Structure Determination
Roy, S. M. (Contributor), Watterson, D. M. (Contributor) & Malliakas, C. (Contributor), Cambridge Crystallographic Data Centre, 2018
DOI: 10.5517/ccdc.csd.cc204n2x, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc204n2x&sid=DataCite
Dataset