Grants per year
Personal profile
Training Experience
| 1999 | Residency, Barnes Jewish Hospital |
| 2000 | Postdoctoral Fellowship, Washington University |
| 2000 | Fellowship, Barnes Jewish Hospital |
Research Interests
Sarki A. Abdulkadir, MD, PhD, is the John T. Grayhack Professor of Urological Research, Vice Chair for Research, and Professor of Urology and Pathology at Northwestern University Feinberg School of Medicine, Chicago. Dr. Abdulkadir’s research program is focused on understanding the molecular mechanisms that drive cancer initiation, progression and recurrence with the ultimate goal of developing therapies that interfere with these processes. His work has particularly focused on prostate cancer. Dr. Abdulkadir has a strong interest in genomics and gene regulation; oncogenic kinases as molecular therapeutic targets; as well as the use of in vivo lineage tracing to define the fates of specific cell populations in tumorigenesis. His work has shed light on the cellular origins of prostate cancer, cancer gene cooperation in tumorigenesis, and the development of novel therapeutic agents currently in preclinical and clinical development.
Education/Academic qualification
PhD, Johns Hopkins University
… → 1995
MD, Ahmadu Bellow University, Nigeria
… → 1990
Fingerprint Dive into the research topics where Sarki Abba Abdulkadir is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 5 Similar Profiles
Prostatic Neoplasms
Medicine & Life Sciences
Prostate
Medicine & Life Sciences
Neoplasms
Medicine & Life Sciences
Carcinogenesis
Medicine & Life Sciences
Genes
Medicine & Life Sciences
Organoids
Medicine & Life Sciences
Castration
Medicine & Life Sciences
Carcinoma
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Grants 2014 2022
Clinical, Environmental, Genetic and Genomic profile of Men with Early Onset Lethal Prostate Cancer
Abdulkadir, S. A., Hussain, M., Jovanovic, B., Meeks, J. J., Morgans, A. K. & Schaeffer, E. M.
12/31/17 → 12/31/19
Project: Research project
Metagenomics
Prostatic Neoplasms
docetaxel
Veterans
Neoplasms
Subproject for Clinical, Environmental, Genetic and Genomic profile of Men with Early Onset Lethal Prostate Cancer
12/31/17 → 12/31/19
Project: Research project
Metagenomics
Prostatic Neoplasms
docetaxel
Veterans
Neoplasms
Tumor immune and glycan biomarkers for progressive prostate cancer
Abdulkadir, S. A., Jovanovic, B. & Wu, J. D.
12/4/17 → 11/30/22
Project: Research project
Polysaccharides
Prostatic Neoplasms
Biomarkers
Neoplasms
Serum
A novel serum and tissue immunoglycomic biomarker panel to distinguish progressive Prostate Cancer
U.S. Army Medical Research and Materiel Command
9/30/17 → 9/29/20
Project: Research project
Prostatic Neoplasms
Biomarkers
Serum
Polysaccharides
Validation Studies
Targeting EZH2 in castration-resistant prostate cancer
Abdulkadir, S. A., Chakravarti, D., Yu, J. & Zhao, C.
U.S. Army Medical Research and Materiel Command
8/1/17 → 7/31/20
Project: Research project
Astemizole
Castration
Nuclear Factor 90 Proteins
Prostatic Neoplasms
Zinc Compounds
Research Output 1990 2019
Organoids increase the predictive value of in vitro cancer chemoprevention studies for in vivo outcome
Njoroge, R. N., Vatapalli, R. J. & Abdulkadir, S. A., Jan 1 2019, In : Frontiers in Oncology. 9, FEB, 77.Research output: Contribution to journal › Review article
Open Access
Organoids
Chemoprevention
Selenium
Vitamin E
Prostatic Neoplasms
Palladium-Catalyzed Coupling Reactions on Functionalized 2-Trifluoromethyl-4-chromenone Scaffolds: Synthesis of Highly Functionalized Trifluoromethyl Heterocycles
Izquierdo, J., Jain, A. D., Abdulkadir, S. A. & Schiltz, G. E., Jan 1 2019, In : Synthesis (Germany). 51, 6, p. 1342-1352 11 p.Research output: Contribution to journal › Article
Fluorine
Palladium
Bioactivity
Biological Products
Scaffolds
Prostate Stroma Increases the Viability and Maintains the Branching Phenotype of Human Prostate Organoids
Richards, Z., McCray, T., Marsili, J., Zenner, M. L., Manlucu, J. T., Garcia, J., Kajdacsy-Balla, A., Murray, M., Voisine, C., Murphy, A. B., Abdulkadir, S. A., Prins, G. S. & Nonn, L., Feb 22 2019, In : iScience. 12, p. 304-317 14 p.Research output: Contribution to journal › Article
Open Access
Organoids
stromal cells
branching
Prostate
viability
6
Citations
(Scopus)
Targeting FOXA1-mediated repression of TGF-β signaling suppresses castration-resistant prostate cancer progression
Song, B., Park, S. H., Zhao, C., Fong, K. W., Li, S., Lee, Y., Yang, Y. A., Sridhar, S., Lu, X., Abdulkadir, S. A., Vessella, R. L., Morrissey, C., Kuzel, T. M., Catalona, W. J., Yang, X. J. & Yu, J., Feb 1 2019, In : Journal of Clinical Investigation. 129, 2, p. 569-582 14 p.Research output: Contribution to journal › Article
LY-2157299
Castration
Androgen Antagonists
Prostatic Neoplasms
Epithelial-Mesenchymal Transition
4
Citations
(Scopus)
The Role of Castration-Resistant Bmi1+Sox2+ Cells in Driving Recurrence in Prostate Cancer
Yoo, Y. A., Vatapalli, R., Lysy, B., Mok, H., Desouki, M. M. & Abdulkadir, S. A., Mar 1 2019, In : Journal of the National Cancer Institute. 111, 3, p. 311-321 11 p.Research output: Contribution to journal › Article
Castration
Prostatic Neoplasms
Recurrence
Neoplasms
Prostate