Grants per year
Personal profile
Training Experience
| 1999 | Residency, Barnes Jewish Hospital |
| 2000 | Postdoctoral Fellowship, Washington University |
| 2000 | Fellowship, Barnes Jewish Hospital |
Research Interests
Sarki A. Abdulkadir, MD, PhD, is the John T. Grayhack Professor of Urological Research, Vice Chair for Research, and Professor of Urology and Pathology at Northwestern University Feinberg School of Medicine, Chicago. Dr. Abdulkadir’s research program is focused on understanding the molecular mechanisms that drive cancer initiation, progression and recurrence with the ultimate goal of developing therapies that interfere with these processes. His work has particularly focused on prostate cancer. Dr. Abdulkadir has a strong interest in genomics and gene regulation; oncogenic kinases as molecular therapeutic targets; as well as the use of in vivo lineage tracing to define the fates of specific cell populations in tumorigenesis. His work has shed light on the cellular origins of prostate cancer, cancer gene cooperation in tumorigenesis, and the development of novel therapeutic agents currently in preclinical and clinical development.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
PhD, Johns Hopkins University
… → 1995
Medicine, MD, Ahmadu Bello University
… → 1990
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Advanced glycation end-products (AGEs) are lower in prostate tumor tissue and inversely related to proportion of West African ancestry
Zenner, M. L., Helou, Y. B., Deaton, R. J., Sverdlov, M., Wang, H., Kajdacsy-Balla, A., Macias, V., Voisine, C., Murray, M., Abdulkadir, S. A., Murphy, A. B. & Nonn, L., Feb 15 2022, In: Prostate. 82, 3, p. 306-313 8 p.Research output: Contribution to journal › Article › peer-review
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A Genome-Wide CRISPR Activation Screen Identifies PRRX2 as a Regulator of Enzalutamide Resistance in Prostate Cancer
Rodríguez, Y., Unno, K., Truica, M. I., Chalmers, Z. R., Yoo, Y. A., Vatapalli, R., Sagar, V., Yu, J., Lysy, B., Hussain, M. H. A., Han, H. & Abdulkadir, S. A., Jun 1 2022, In: Cancer Research. 82, 11, p. 2110-2123 14 p.Research output: Contribution to journal › Article › peer-review
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A MYC inhibitor selectively alters the MYC and MAX cistromes and modulates the epigenomic landscape to regulate target gene expression
Holmes, A. G., Parker, J. B., Sagar, V., Truica, M. I., Soni, P. N., Han, H., Schiltz, G. E., Abdulkadir, S. A. & Chakravarti, D., Apr 2022, In: Science Advances. 8, 17, eabh3635.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Correction: Inflammatory bowel disease induces inflammatory and preneoplastic changes in the prostate (Prostate Cancer and Prostatic Diseases, (2021), 10.1038/s41391-021-00392-7)
Desai, A. S., Sagar, V., Lysy, B., Weiner, A. B., Ko, O. S., Driscoll, C., Rodriguez, Y., Vatapalli, R., Unno, K., Han, H., Cohen, J. E., Vo, A. X., Pham, M., Shin, M., Jain-Poster, K., Ross, J., Morency, E. G., Meyers, T. J., Witte, J. S., Wu, J., & 2 others, Feb 2022, In: Prostate Cancer and Prostatic Diseases. 25, 2, p. 375 1 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access -
Inflammatory bowel disease induces inflammatory and pre-neoplastic changes in the prostate
Desai, A. S., Sagar, V., Lysy, B., Weiner, A. B., Ko, O. S., Driscoll, C., Rodriguez, Y., Vatapalli, R., Unno, K., Han, H., Cohen, J. E., Vo, A. X., Pham, M., Shin, M., Jain-Poster, K., Ross, J., Morency, E. G., Meyers, T. J., Witte, J. S., Wu, J., & 2 others, Sep 2022, In: Prostate Cancer and Prostatic Diseases. 25, 3, p. 463-471 9 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations