Grants per year
Personal profile
Training Experience
| 1999 | Residency, Barnes Jewish Hospital |
| 2000 | Postdoctoral Fellowship, Washington University |
| 2000 | Fellowship, Barnes Jewish Hospital |
Research Interests
Sarki A. Abdulkadir, MD, PhD, is the John T. Grayhack Professor of Urological Research, Vice Chair for Research, and Professor of Urology and Pathology at Northwestern University Feinberg School of Medicine, Chicago. Dr. Abdulkadir’s research program is focused on understanding the molecular mechanisms that drive cancer initiation, progression and recurrence with the ultimate goal of developing therapies that interfere with these processes. His work has particularly focused on prostate cancer. Dr. Abdulkadir has a strong interest in genomics and gene regulation; oncogenic kinases as molecular therapeutic targets; as well as the use of in vivo lineage tracing to define the fates of specific cell populations in tumorigenesis. His work has shed light on the cellular origins of prostate cancer, cancer gene cooperation in tumorigenesis, and the development of novel therapeutic agents currently in preclinical and clinical development.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
PhD, Immunology, Johns Hopkins University
… → 1995
Medicine, MD, Ahmadu Bello University
… → 1990
Fingerprint
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Exploiting therapeutic vulnerabilities in hepatocellular carcinoma (ELEVATE)
Abdulkadir, S. A. (PD/PI)
Virginia Commonwealth University, National Cancer Institute
8/8/24 → 7/31/29
Project: Research project
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A novel role for EZH2 in PARP regulation and PARPi-resistance in prostate cancer
Cao, Q. (PD/PI), Abdulkadir, S. A. (Co-Investigator) & Yang, R. (Co-Investigator)
7/12/24 → 6/30/29
Project: Research project
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A novel role for EZH2 in A-to-I RNA editing in prostate cancer
Cao, Q. (PD/PI), Abdulkadir, S. A. (Co-Investigator) & Schaeffer, E. M. (Co-Investigator)
2/5/24 → 1/31/29
Project: Research project
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The Role of EZH2-ADAR1 Axis in Advanced Prostate Cancer
Yi, Y. (PD/PI), Abdulkadir, S. A. (Co-Investigator) & Yang, R. (Co-Investigator)
U.S. Army Medical Research and Materiel Command
9/29/23 → 9/28/26
Project: Research project
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Tactical Approaches to Repress oncogenic Gene Expression in prostatic Tumors (TARGET)
Abdulkadir, S. A. (PD/PI), Abdulkadir, S. A. (PD/PI), Fenton, S. E. (Co-Investigator), Fenton, S. E. (Co-Investigator), Hussain, M. (Co-Investigator), Hussain, M. (Co-Investigator), Schiltz, G. E. (Co-Investigator) & Schiltz, G. E. (Co-Investigator)
University of Michigan, Prostate Cancer Foundation
2/10/23 → 2/9/26
Project: Research project
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A surrogate molecular approach for the detection of Philadelphia chromosome–like B-acute lymphoblastic leukemia
Gupta, D. G., Varma, N., Abdulkadir, S. A., Sreedharanunni, S., Sachdeva, M. U. S., Naseem, S., Bose, P., Binota, J., Malhotra, P., Khadwal, A., Trehan, A. & Varma, S., Mar 1 2024, In: cancer. 130, 5, p. 713-726 14 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Mechanism-centric regulatory network identifies NME2 and MYC programs as markers of Enzalutamide resistance in CRPC
Panja, S., Truica, M. I., Yu, C. Y., Saggurthi, V., Craige, M. W., Whitehead, K., Tuiche, M. V., Al-Saadi, A., Vyas, R., Ganesan, S., Gohel, S., Coffman, F., Parrott, J. S., Quan, S., Jha, S., Kim, I., Schaeffer, E., Kothari, V., Abdulkadir, S. A. & Mitrofanova, A., Dec 2024, In: Nature communications. 15, 1, 352.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Hematological, clinical, immunophenotypic characterization, and treatment outcomes of prognostically significant genetic subtypes of B-lineage acute lymphoblastic leukemia: A report of 1021 patients from India
Gupta, D. G., Varma, N., Sharma, P., Truica, M. I., Abdulkadir, S. A., Singh, P., Singh Sachdeva, M. U., Naseem, S., Siddiqui, M. R., Bose, P., Binota, J., Malhotra, P., Khadwal, A., Trehan, A. & Varma, S., Nov 1 2023, In: cancer. 129, 21, p. 3390-3404 15 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Identification and validation of the optimal reference genes for standardizing the gene expression profiling diagnostic panel of Ph-like B-lineage acute lymphoblastic leukemia
Gupta, D. G., Varma, N., Abdulkadir, S. A., Singh, P., Sachdeva, M. U. S., Naseem, S., Siddiqui, M. R., Bose, P., Binota, J., Malhotra, P., Khadwal, A. & Varma, S., Dec 2023, In: Clinical and Experimental Medicine. 23, 8, p. 4539-4551 13 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
‘Evaluation of adverse prognostic gene alterations & MRD positivity in BCR::ABL1-like B-lineage acute lymphoblastic leukaemia patients, in a resource-constrained setting
Gupta, D. G., Varma, N., Sreedharanunni, S., Abdulkadir, S. A., Naseem, S., Sachdeva, M. U. S., Binota, J., Bose, P., Malhotra, P., Khadwal, A. & Varma, S., Jul 27 2023, In: British Journal of Cancer. 129, 1, p. 143-152 10 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations
Datasets
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CCDC 1840656: Experimental Crystal Structure Determination
Izquierdo, J. (Creator), Jain, A. D. (Creator), Abdulkadir, S. A. (Creator) & Schiltz, G. E. (Creator), Cambridge Crystallographic Data Centre, 2018
DOI: 10.5517/ccdc.csd.cc1zsc04, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc1zsc04&sid=DataCite
Dataset
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CCDC 1840657: Experimental Crystal Structure Determination
Izquierdo, J. (Creator), Jain, A. D. (Creator), Abdulkadir, S. A. (Creator) & Schiltz, G. E. (Creator), Cambridge Crystallographic Data Centre, 2018
DOI: 10.5517/ccdc.csd.cc1zsc15, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc1zsc15&sid=DataCite
Dataset