Grants per year
Personal profile
Training Experience
1999 | Residency, Barnes Jewish Hospital |
2000 | Postdoctoral Fellowship, Washington University |
2000 | Fellowship, Barnes Jewish Hospital |
Research Interests
Sarki A. Abdulkadir, MD, PhD, is the John T. Grayhack Professor of Urological Research, Vice Chair for Research, and Professor of Urology and Pathology at Northwestern University Feinberg School of Medicine, Chicago. Dr. Abdulkadir’s research program is focused on understanding the molecular mechanisms that drive cancer initiation, progression and recurrence with the ultimate goal of developing therapies that interfere with these processes. His work has particularly focused on prostate cancer. Dr. Abdulkadir has a strong interest in genomics and gene regulation; oncogenic kinases as molecular therapeutic targets; as well as the use of in vivo lineage tracing to define the fates of specific cell populations in tumorigenesis. His work has shed light on the cellular origins of prostate cancer, cancer gene cooperation in tumorigenesis, and the development of novel therapeutic agents currently in preclinical and clinical development.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
PhD, Immunology, Johns Hopkins University
… → 1995
Medicine, MD, Ahmadu Bello University
… → 1990
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Collaborations and top research areas from the last five years
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Exploiting therapeutic vulnerabilities in hepatocellular carcinoma (ELEVATE)
Abdulkadir, S. A. (PD/PI)
Virginia Commonwealth University, National Cancer Institute
8/8/24 → 7/31/29
Project: Research project
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A novel role for EZH2 in PARP regulation and PARPi-resistance in prostate cancer
Cao, Q. (PD/PI), Abdulkadir, S. A. (Co-Investigator) & Yang, R. (Co-Investigator)
7/12/24 → 6/30/29
Project: Research project
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A novel role for EZH2 in A-to-I RNA editing in prostate cancer
Cao, Q. (PD/PI), Abdulkadir, S. A. (Co-Investigator), Schaeffer, E. M. (Co-Investigator) & Meng, Q. (Other)
2/5/24 → 1/31/29
Project: Research project
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The Role of EZH2-ADAR1 Axis in Advanced Prostate Cancer
Yi, Y. (PD/PI), Yi, Y. (PD/PI), Abdulkadir, S. A. (Co-Investigator), Abdulkadir, S. A. (Co-Investigator), Yang, R. (Co-Investigator) & Yang, R. (Co-Investigator)
U.S. Army Medical Research and Materiel Command
9/29/23 → 9/28/26
Project: Research project
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CCSG Senior Leadership
Platanias, L. C. (PD/PI), Abdulkadir, S. A. (Other), Cella, D. (Other), Green, K. J. (Other) & Hussain, M. (Other)
8/1/23 → 7/31/25
Project: Research project
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Death ligand receptor (DLR) signaling: Its non-apoptotic functions in cancer and the consequences of DLR-directed therapies
Rashid, K., Kalthoff, H., Abdulkadir, S. A. & Adam, D., Feb 2025, In: Drug Discovery Today. 30, 2, 104299.Research output: Contribution to journal › Review article › peer-review
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PIM kinase inhibition counters resistance to radiotherapy and chemotherapy in human prostate cancer
Rajkumar-Calkins, A., Sagar, V., Wang, J., Bailey, S., Anderson, P., Abdulkadir, S. A. & Kirschner, A. N., May 2025, In: Radiotherapy and Oncology. 206, 110794.Research output: Contribution to journal › Article › peer-review
Open Access -
Unlocking the Radiosensitizing Potential of MYC Inhibition in Neuroendocrine Malignancies
Guo, Q., Yang, W., Robinson, G., Chaludiya, K., Abdulkadir, A. N., Roy, F. G., Shivakumar, D., Ahmad, A. N., Abdulkadir, S. A. & Kirschner, A. N., Aug 1 2025, In: International Journal of Radiation Oncology Biology Physics. 122, 5, p. 1310-1326 17 p.Research output: Contribution to journal › Review article › peer-review
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Asparagine Dependency Is a Targetable Metabolic Vulnerability in TP53-Altered Castration-Resistant Prostate Cancer
Yoo, Y. A., Quan, S., Yang, W., Guo, Q., Rodríguez, Y., Chalmers, Z. R., Dufficy, M. F., Lackie, B., Sagar, V., Unno, K., Truica, M. I., Chandel, N. S. & Abdulkadir, S. A., Sep 15 2024, In: Cancer Research. 84, 18, p. 3004-3022 19 p.Research output: Contribution to journal › Article › peer-review
8 Scopus citations -
A surrogate molecular approach for the detection of Philadelphia chromosome–like B-acute lymphoblastic leukemia
Gupta, D. G., Varma, N., Abdulkadir, S. A., Sreedharanunni, S., Sachdeva, M. U. S., Naseem, S., Bose, P., Binota, J., Malhotra, P., Khadwal, A., Trehan, A. & Varma, S., Mar 1 2024, In: cancer. 130, 5, p. 713-726 14 p.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations
Datasets
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CCDC 1840656: Experimental Crystal Structure Determination
Izquierdo, J. (Creator), Jain, A. D. (Creator), Abdulkadir, S. A. (Creator) & Schiltz, G. E. (Creator), Cambridge Crystallographic Data Centre, 2018
DOI: 10.5517/ccdc.csd.cc1zsc04, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc1zsc04&sid=DataCite
Dataset
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CCDC 1840657: Experimental Crystal Structure Determination
Izquierdo, J. (Creator), Jain, A. D. (Creator), Abdulkadir, S. A. (Creator) & Schiltz, G. E. (Creator), Cambridge Crystallographic Data Centre, 2018
DOI: 10.5517/ccdc.csd.cc1zsc15, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc1zsc15&sid=DataCite
Dataset