Sarki Abba Abdulkadir

  • 2620 Citations
1990 …2022
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Personal profile

Training Experience

1999Residency, Barnes Jewish Hospital
2000Postdoctoral Fellowship, Washington University
2000Fellowship, Barnes Jewish Hospital

Research Interests

Sarki A. Abdulkadir, MD, PhD, is the John T. Grayhack Professor of Urological Research, Vice Chair for Research, and Professor of Urology and Pathology at Northwestern University Feinberg School of Medicine, Chicago. Dr. Abdulkadir’s research program is focused on understanding the molecular mechanisms that drive cancer initiation, progression and recurrence with the ultimate goal of developing therapies that interfere with these processes. His work has particularly focused on prostate cancer. Dr. Abdulkadir has a strong interest in genomics and gene regulation; oncogenic kinases as molecular therapeutic targets; as well as the use of in vivo lineage tracing to define the fates of specific cell populations in tumorigenesis. His work has shed light on the cellular origins of prostate cancer, cancer gene cooperation in tumorigenesis, and the development of novel therapeutic agents currently in preclinical and clinical development.

Education/Academic qualification

PhD, Johns Hopkins University

… → 1995

MD, Ahmadu Bellow University, Nigeria

… → 1990

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  • 6 Similar Profiles
Prostatic Neoplasms Medicine & Life Sciences
Prostate Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Carcinogenesis Medicine & Life Sciences
Genes Medicine & Life Sciences
Organoids Medicine & Life Sciences
Castration Medicine & Life Sciences
Tumors Chemical Compounds

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Grants 2014 2022

Prostatic Neoplasms
Proteasome Endopeptidase Complex
Prostatic Neoplasms
Prostatic Neoplasms

Research Output 1990 2019

  • 2620 Citations
  • 54 Article
  • 4 Review article
  • 1 Comment/debate
  • 1 Letter

EPHB4 inhibition activates ER stress to promote immunogenic cell death of prostate cancer cells

Sagar, V., Vatapalli, R., Lysy, B., Pamarthy, S., Anker, J. F., Rodriguez, Y., Han, H., Unno, K., Stadler, W. M., Catalona, W. J., Hussain, M., Gill, P. S. & Abdulkadir, S. A., Nov 1 2019, In : Cell Death and Disease. 10, 11, 801.

Research output: Contribution to journalArticle

Open Access
Prostatic Neoplasms
Cell Death
Adenosine Triphosphate
2 Citations (Scopus)

Nivolumab in Metastatic Adrenocortical Carcinoma: Results of a Phase 2 Trial

Carneiro, B. A., Konda, B., Costa, R. B., Costa, R. L. B., Sagar, V., Gursel, D. B., Kirschner, L. S., Chae, Y. K., Abdulkadir, S. A., Rademaker, A., Mahalingam, D., Shah, M. H. & Giles, F. J., Dec 1 2019, In : The Journal of clinical endocrinology and metabolism. 104, 12, p. 6193-6200 8 p.

Research output: Contribution to journalArticle

Adrenocortical Carcinoma
Drug Therapy
Disease-Free Survival

Organoids increase the predictive value of in vitro cancer chemoprevention studies for in vivo outcome

Njoroge, R. N., Vatapalli, R. J. & Abdulkadir, S. A., Jan 1 2019, In : Frontiers in Oncology. 9, FEB, 77.

Research output: Contribution to journalReview article

Open Access
Vitamin E
Prostatic Neoplasms
2 Citations (Scopus)
Biological Products

Prostate Stroma Increases the Viability and Maintains the Branching Phenotype of Human Prostate Organoids

Richards, Z., McCray, T., Marsili, J., Zenner, M. L., Manlucu, J. T., Garcia, J., Kajdacsy-Balla, A., Murray, M., Voisine, C., Murphy, A. B., Abdulkadir, S. A., Prins, G. S. & Nonn, L., Feb 22 2019, In : iScience. 12, p. 304-317 14 p.

Research output: Contribution to journalArticle

Open Access
stromal cells