Grants per year
Personal profile
Training Experience
| 1999 | Residency, Barnes Jewish Hospital |
| 2000 | Postdoctoral Fellowship, Washington University |
| 2000 | Fellowship, Barnes Jewish Hospital |
Research Interests
Sarki A. Abdulkadir, MD, PhD, is the John T. Grayhack Professor of Urological Research, Vice Chair for Research, and Professor of Urology and Pathology at Northwestern University Feinberg School of Medicine, Chicago. Dr. Abdulkadir’s research program is focused on understanding the molecular mechanisms that drive cancer initiation, progression and recurrence with the ultimate goal of developing therapies that interfere with these processes. His work has particularly focused on prostate cancer. Dr. Abdulkadir has a strong interest in genomics and gene regulation; oncogenic kinases as molecular therapeutic targets; as well as the use of in vivo lineage tracing to define the fates of specific cell populations in tumorigenesis. His work has shed light on the cellular origins of prostate cancer, cancer gene cooperation in tumorigenesis, and the development of novel therapeutic agents currently in preclinical and clinical development.
Education/Academic qualification
PhD, Johns Hopkins University
… → 1995
MD, Ahmadu Bello University
… → 1990
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Grants
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Targeting nuclear EGFR and AURKA as a therapy for anti-androgen resistance in TP53- and RB1-deficient prostate cancer
Abdulkadir, S. A. & Yoo, Y. A.
7/1/20 → 6/30/21
Project: Research project
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CardioExcyte 96 System for Pharmacology Research at Northwestern University
Abdulkadir, S. A., Ardehali, H., Arora, R. K., Burridge, P., George Jr, A. L., Kearney, J. A., McNally, E. M., Schiltz, G. E., Silverman, R. B., Watterson, D. M. & Wilsbacher, L. D.
Office of the Director, National Institutes of Health
6/15/20 → 6/14/21
Project: Research project
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Subproject for Clinical, Environmental, Genetic and Genomic profile of Men with Early Onset Lethal Prostate Cancer
12/31/17 → 12/31/20
Project: Research project
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Clinical, Environmental, Genetic and Genomic profile of Men with Early Onset Lethal Prostate Cancer
Abdulkadir, S. A., Hussain, M., Jovanovic, B., Meeks, J. J., Morgans, A. K. & Schaeffer, E. M.
12/31/17 → 12/31/20
Project: Research project
Research Output
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Association between inflammatory bowel disease and prostate cancer: A large-scale, prospective, population-based study
Meyers, T. J., Weiner, A. B., Graff, R. E., Desai, A. S., Cooley, L. F., Catalona, W. J., Hanauer, S. B., Wu, J. D., Schaeffer, E. M., Abdulkadir, S. A., Kundu, S. D. & Witte, J. S., Nov 15 2020, In: International Journal of Cancer. 147, 10, p. 2735-2742 8 p.Research output: Contribution to journal › Article › peer-review
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Histone methyltransferase DOT1L coordinates AR and MYC stability in prostate cancer
Vatapalli, R., Sagar, V., Rodriguez, Y., Zhao, J. C., Unno, K., Pamarthy, S., Lysy, B., Anker, J., Han, H., Yoo, Y. A., Truica, M., Chalmers, Z. R., Giles, F., Yu, J., Chakravarti, D., Carneiro, B. & Abdulkadir, S. A., Dec 1 2020, In: Nature communications. 11, 1, 4153.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Macrophages expedite cell proliferation of prostate intraepithelial neoplasia through their downstream target ERK
Thomas, M. U., Messex, J. K., Dang, T., Abdulkadir, S. A., Jorcyk, C. L. & Liou, G. Y., 2020, (Accepted/In press) In: FEBS Journal.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
EPHB4 inhibition activates ER stress to promote immunogenic cell death of prostate cancer cells
Sagar, V., Vatapalli, R., Lysy, B., Pamarthy, S., Anker, J. F., Rodriguez, Y., Han, H., Unno, K., Stadler, W. M., Catalona, W. J., Hussain, M., Gill, P. S. & Abdulkadir, S. A., Nov 1 2019, In: Cell Death and Disease. 10, 11, 801.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
Nivolumab in Metastatic Adrenocortical Carcinoma: Results of a Phase 2 Trial
Carneiro, B. A., Konda, B., Costa, R. B., Costa, R. L. B., Sagar, V., Gursel, D. B., Kirschner, L. S., Chae, Y. K., Abdulkadir, S. A., Rademaker, A., Mahalingam, D., Shah, M. H. & Giles, F. J., Dec 1 2019, In: Journal of Clinical Endocrinology and Metabolism. 104, 12, p. 6193-6200 8 p.Research output: Contribution to journal › Article › peer-review
12 Scopus citations