Sarki Abba Abdulkadir

  • 2553 Citations
1990 …2022
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Personal profile

Training Experience

1999Residency, Barnes Jewish Hospital
2000Postdoctoral Fellowship, Washington University
2000Fellowship, Barnes Jewish Hospital

Research Interests

Sarki A. Abdulkadir, MD, PhD, is the John T. Grayhack Professor of Urological Research, Vice Chair for Research, and Professor of Urology and Pathology at Northwestern University Feinberg School of Medicine, Chicago. Dr. Abdulkadir’s research program is focused on understanding the molecular mechanisms that drive cancer initiation, progression and recurrence with the ultimate goal of developing therapies that interfere with these processes. His work has particularly focused on prostate cancer. Dr. Abdulkadir has a strong interest in genomics and gene regulation; oncogenic kinases as molecular therapeutic targets; as well as the use of in vivo lineage tracing to define the fates of specific cell populations in tumorigenesis. His work has shed light on the cellular origins of prostate cancer, cancer gene cooperation in tumorigenesis, and the development of novel therapeutic agents currently in preclinical and clinical development.

Education/Academic qualification

PhD, Johns Hopkins University

… → 1995

MD, Ahmadu Bellow University, Nigeria

… → 1990

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  • 7 Similar Profiles
Prostatic Neoplasms Medicine & Life Sciences
Prostate Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Carcinogenesis Medicine & Life Sciences
Genes Medicine & Life Sciences
Organoids Medicine & Life Sciences
Castration Medicine & Life Sciences
Carcinoma Medicine & Life Sciences

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Grants 2014 2022

Metagenomics
Prostatic Neoplasms
docetaxel
Veterans
Neoplasms
Polysaccharides
Prostatic Neoplasms
Biomarkers
Neoplasms
Serum
Prostatic Neoplasms
Biomarkers
Serum
Polysaccharides
Validation Studies
Astemizole
Castration
Nuclear Factor 90 Proteins
Prostatic Neoplasms
Zinc Compounds

Research Output 1990 2019

  • 2553 Citations
  • 51 Article
  • 4 Review article
  • 1 Comment/debate
  • 1 Letter

Organoids increase the predictive value of in vitro cancer chemoprevention studies for in vivo outcome

Njoroge, R. N., Vatapalli, R. J. & Abdulkadir, S. A., Jan 1 2019, In : Frontiers in Oncology. 9, FEB, 77.

Research output: Contribution to journalReview article

Open Access
Organoids
Chemoprevention
Selenium
Vitamin E
Prostatic Neoplasms
Fluorine
Palladium
Bioactivity
Biological Products
Scaffolds

Prostate Stroma Increases the Viability and Maintains the Branching Phenotype of Human Prostate Organoids

Richards, Z., McCray, T., Marsili, J., Zenner, M. L., Manlucu, J. T., Garcia, J., Kajdacsy-Balla, A., Murray, M., Voisine, C., Murphy, A. B., Abdulkadir, S. A., Prins, G. S. & Nonn, L., Feb 22 2019, In : iScience. 12, p. 304-317 14 p.

Research output: Contribution to journalArticle

Open Access
Organoids
stromal cells
branching
Prostate
viability
7 Citations (Scopus)

Targeting FOXA1-mediated repression of TGF-β signaling suppresses castration-resistant prostate cancer progression

Song, B., Park, S. H., Zhao, C., Fong, K. W., Li, S., Lee, Y., Yang, Y. A., Sridhar, S., Lu, X., Abdulkadir, S. A., Vessella, R. L., Morrissey, C., Kuzel, T. M., Catalona, W. J., Yang, X. J. & Yu, J., Feb 1 2019, In : Journal of Clinical Investigation. 129, 2, p. 569-582 14 p.

Research output: Contribution to journalArticle

LY-2157299
Castration
Androgen Antagonists
Prostatic Neoplasms
Epithelial-Mesenchymal Transition
4 Citations (Scopus)

The Role of Castration-Resistant Bmi1+Sox2+ Cells in Driving Recurrence in Prostate Cancer

Yoo, Y. A., Vatapalli, R., Lysy, B., Mok, H., Desouki, M. M. & Abdulkadir, S. A., Mar 1 2019, In : Journal of the National Cancer Institute. 111, 3, p. 311-321 11 p.

Research output: Contribution to journalArticle

Castration
Prostatic Neoplasms
Recurrence
Neoplasms
Prostate