Sarki Abba Abdulkadir

  • 2779 Citations
1990 …2020

Research output per year

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Research Output

  • 2779 Citations
  • 54 Article
  • 5 Review article
  • 1 Comment/debate
  • 1 Letter
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Article
2020

Association between inflammatory bowel disease and prostate cancer: A large-scale, prospective, population-based study

Meyers, T. J., Weiner, A. B., Graff, R. E., Desai, A. S., Cooley, L. F., Catalona, W. J., Hanauer, S. B., Wu, J. D., Schaeffer, E. M., Abdulkadir, S. A., Kundu, S. D. & Witte, J. S., 2020, (Accepted/In press) In : International Journal of Cancer.

Research output: Contribution to journalArticle

2019

EPHB4 inhibition activates ER stress to promote immunogenic cell death of prostate cancer cells

Sagar, V., Vatapalli, R., Lysy, B., Pamarthy, S., Anker, J. F., Rodriguez, Y., Han, H., Unno, K., Stadler, W. M., Catalona, W. J., Hussain, M., Gill, P. S. & Abdulkadir, S. A., Nov 1 2019, In : Cell Death and Disease. 10, 11, 801.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

Nivolumab in Metastatic Adrenocortical Carcinoma: Results of a Phase 2 Trial

Carneiro, B. A., Konda, B., Costa, R. B., Costa, R. L. B., Sagar, V., Gursel, D. B., Kirschner, L. S., Chae, Y. K., Abdulkadir, S. A., Rademaker, A., Mahalingam, D., Shah, M. H. & Giles, F. J., Dec 1 2019, In : Journal of Clinical Endocrinology and Metabolism. 104, 12, p. 6193-6200 8 p.

Research output: Contribution to journalArticle

7 Scopus citations
2 Scopus citations

Prostate Stroma Increases the Viability and Maintains the Branching Phenotype of Human Prostate Organoids

Richards, Z., McCray, T., Marsili, J., Zenner, M. L., Manlucu, J. T., Garcia, J., Kajdacsy-Balla, A., Murray, M., Voisine, C., Murphy, A. B., Abdulkadir, S. A., Prins, G. S. & Nonn, L., Feb 22 2019, In : iScience. 12, p. 304-317 14 p.

Research output: Contribution to journalArticle

Open Access
11 Scopus citations

Small-Molecule MYC Inhibitors Suppress Tumor Growth and Enhance Immunotherapy

Han, H., Jain, A. D., Truica, M. I., Izquierdo-Ferrer, J., Anker, J. F., Lysy, B., Sagar, V., Luan, Y., Chalmers, Z. R., Unno, K., Mok, H., Vatapalli, R., Yoo, Y. A., Rodriguez, Y., Kandela, I., Parker, J. B., Chakravarti, D., Mishra, R. K., Schiltz, G. E. & Abdulkadir, S. A., Nov 11 2019, In : Cancer Cell. 36, 5, p. 483-497.e15

Research output: Contribution to journalArticle

7 Scopus citations

Targeting FOXA1-mediated repression of TGF-β signaling suppresses castration-resistant prostate cancer progression

Song, B., Park, S. H., Zhao, J. C., Fong, K. W., Li, S., Lee, Y., Yang, Y. A., Sridhar, S., Lu, X., Abdulkadir, S. A., Vessella, R. L., Morrissey, C., Kuzel, T. M., Catalona, W., Yang, X. & Yu, J., Feb 1 2019, In : Journal of Clinical Investigation. 129, 2, p. 569-582 14 p.

Research output: Contribution to journalArticle

20 Scopus citations

The role of castration-resistant Bmi1+Sox2+ cells in driving recurrence in prostate cancer

Yoo, Y. A., Vatapalli, R., Lysy, B., Mok, H., Desouki, M. M. & Abdulkadir, S. A., Jan 1 2019, In : Journal of the National Cancer Institute. 111, 3, p. 311-321 11 p.

Research output: Contribution to journalArticle

7 Scopus citations
2018

A bioluminescent and fluorescent orthotopic syngeneic murine model of androgen-dependent and castration-resistant prostate cancer

Anker, J. F., Mok, H., Naseem, A. F., Thumbikat, P. & Abdulkadir, S. A., Mar 6 2018, In : Journal of Visualized Experiments. 2018, 133, e57301.

Research output: Contribution to journalArticle

1 Scopus citations

Anaplastic lymphoma kinase mutation (ALK F1174C) in small cell carcinoma of the prostate and molecular response to alectinib

Carneiro, B. A., Pamarthy, S., Shah, A. N., Sagar, V., Unno, K., Han, H. Y., Yang, X. J., Costa, R. B., Nagy, R. J., Lanman, R. B., Kuzel, T. M., Ross, J. S., Gay, L., Elvin, J. A., Ali, S. M., Cristofanilli, M., Chae, Y. K., Giles, F. J. & Abdulkadir, S. A., Jun 15 2018, In : Clinical Cancer Research. 24, 12, p. 2732-2739 8 p.

Research output: Contribution to journalArticle

7 Scopus citations

Multi-faceted immunomodulatory and tissue-tropic clinical bacterial isolate potentiates prostate cancer immunotherapy

Anker, J. F., Naseem, A. F., Mok, H., Schaeffer, A. J., Abdulkadir, S. A. & Thumbikat, P., Dec 1 2018, In : Nature communications. 9, 1, 1591.

Research output: Contribution to journalArticle

16 Scopus citations
2017

Modeling African American prostate adenocarcinoma by inducing defined genetic alterations in organoids

Unno, K., Roh, M., Yoo, Y. A., Al-Shraideh, Y., Wang, L., Nonn, L. & Abdulkadir, S. A., Feb 7 2017, In : Oncotarget. 8, 31, p. 51264-51276 13 p.

Research output: Contribution to journalArticle

9 Scopus citations

Organoids model distinct Vitamin E effects at different stages of prostate cancer evolution

Njoroge, R. N., Unno, K., Zhao, J. C., Naseem, A. F., Anker, J. F., McGee, W. A., Nonn, L. & Abdulkadir, S. A., Dec 1 2017, In : Scientific reports. 7, 1, 16285.

Research output: Contribution to journalArticle

5 Scopus citations
2016

Bmi1 marks distinct castration-resistant luminal progenitor cells competent for prostate regeneration and tumour initiation

Yoo, Y. A., Roh, M., Naseem, A. F., Lysy, B., Desouki, M. M., Unno, K. & Abdulkadir, S. A., Oct 5 2016, In : Nature communications. 7, 12943.

Research output: Contribution to journalArticle

29 Scopus citations

KAT8 regulates androgen signaling in prostate cancer cells

Kim, J. Y., Yu, J., Abdulkadir, S. A. & Chakravarti, D., Aug 2016, In : Molecular Endocrinology. 30, 8, p. 925-936 12 p.

Research output: Contribution to journalArticle

6 Scopus citations
2015

PIM kinase inhibitor AZD1208 for treatment of MYC-driven prostate cancer

N. Kirschner, A., Wang, J., Van Der Meer, R., Anderson, P. D., Franco-Coronel, O. E., Kushner, M. H., Everett, J. H., Hameed, O., Keeton, E. K., Ahdesmaki, M., Grosskurth, S. E., Huszar, D. & Abdulkadir, S. A., Feb 1 2015, In : Journal of the National Cancer Institute. 107, 2, dju407.

Research output: Contribution to journalArticle

40 Scopus citations
2014

A functional variant in NKX3.1 associated with prostate cancer risk in the Selenium and Vitamin e Cancer Prevention Trial (SELECT)

Martinez, E. E., Darke, A. K., Tangen, C. M., Goodman, P. J., Fowke, J. H., Klein, E. A. & Abdulkadir, S. A., Sep 1 2014, In : Cancer Prevention Research. 7, 9, p. 950-957 8 p.

Research output: Contribution to journalArticle

17 Scopus citations

Decreased mitochondrial SIRT3 expression is a potential molecular biomarker associated with poor outcome in breast cancer

Desouki, M. M., Doubinskaia, I., Gius, D. & Abdulkadir, S. A., Jan 1 2014, In : Human Pathology. 45, 5, p. 1071-1077 7 p.

Research output: Contribution to journalArticle

40 Scopus citations

PIM1 kinase as a target in prostate cancer: Roles in tumorigenesis, castration resistance, and docetaxel resistance

Holder, S. L. & Abdulkadir, S. A., Jan 1 2014, In : Current Cancer Drug Targets. 14, 2, p. 105-114 10 p.

Research output: Contribution to journalArticle

18 Scopus citations

RNAi screen identifies a synthetic lethal interaction between PIM1 overexpression and PLK1 inhibition

Van Der Meer, R., Song, H. Y., Park, S. H., Abdulkadir, S. A. & Roh, M., Jun 15 2014, In : Clinical Cancer Research. 20, 12, p. 3211-3221 11 p.

Research output: Contribution to journalArticle

16 Scopus citations
2013

RAMP1 is a direct NKX3.1 target gene up-regulated in prostate cancer that promotes tumorigenesis

Logan, M., Anderson, P. D., Saab, S. T., Hameed, O. & Abdulkadir, S. A., Sep 1 2013, In : American Journal of Pathology. 183, 3, p. 951-963 13 p.

Research output: Contribution to journalArticle

7 Scopus citations

Selective COX-2 inhibitor (celecoxib) decreases cellular growth in prostate cancer cell lines independent of p53

Katkoori, V. R., Manne, K., Vital-Reyes, V. S., Rodríguez-Burford, C., Shanmugam, C., Sthanam, M., Manne, U., Chatla, C., Abdulkadir, S. A. & Grizzle, W. E., Jan 2013, In : Biotechnic and Histochemistry. 88, 1, p. 38-46 9 p.

Research output: Contribution to journalArticle

15 Scopus citations
2012

A mouse model of heterogeneous, c-MYC-initiated prostate cancer with loss of Pten and p53

Kim, J., Roh, M., Doubinskaia, I., Algarroba, G. N., Eltoum, I. E. A. & Abdulkadir, S. A., Jan 19 2012, In : Oncogene. 31, 3, p. 322-332 11 p.

Research output: Contribution to journalArticle

34 Scopus citations

Antioxidant Treatment Promotes Prostate Epithelial Proliferation in Nkx3.1 Mutant Mice

Martinez, E. E., Anderson, P. D., Logan, M. & Abdulkadir, S. A., Oct 15 2012, In : PloS one. 7, 10, e46792.

Research output: Contribution to journalArticle

14 Scopus citations

Nkx3.1 and Myc crossregulate shared target genes in mouse and human prostate tumorigenesis

Anderson, P. D., McKissic, S. A., Logan, M., Roh, M., Franco, O. E., Wang, J., Doubinskaia, I., Van Der Meer, R., Hayward, S. W., Eischen, C. M., Eltoum, I. E. & Abdulkadir, S. A., May 1 2012, In : Journal of Clinical Investigation. 122, 5, p. 1907-1919 13 p.

Research output: Contribution to journalArticle

34 Scopus citations

Pim1 kinase is required to maintain tumorigenicity in MYC-expressing prostate cancer cells

Wang, J., Anderson, P. D., Luo, W., Gius, D., Roh, M. & Abdulkadir, S. A., Apr 5 2012, In : Oncogene. 31, 14, p. 1794-1803 10 p.

Research output: Contribution to journalArticle

48 Scopus citations

Tumorigenic polyploid cells contain elevated ROS and ARE selectively targeted by antioxidant treatment

Roh, M., van der Meer, R. & Abdulkadir, S. A., Jan 1 2012, In : Journal of Cellular Physiology. 227, 2, p. 801-812 12 p.

Research output: Contribution to journalArticle

22 Scopus citations
2010

Pim1 kinase synergizes with c-MYC to induce advanced prostate carcinoma

Wang, J., Kim, J., Roh, M., Franco, O. E., Hayward, S. W., Wills, M. L. & Abdulkadir, S. A., Apr 1 2010, In : Oncogene. 29, 17, p. 2477-2487 11 p.

Research output: Contribution to journalArticle

90 Scopus citations

Pim1 promotes human prostate cancer cell tumorigenicity and c-MYC transcriptional activity

Kim, J., Roh, M. & Abdulkadir, S. A., Jun 1 2010, In : BMC Cancer. 10, 248.

Research output: Contribution to journalArticle

57 Scopus citations

SIRT3 Is a Mitochondria-Localized Tumor Suppressor Required for Maintenance of Mitochondrial Integrity and Metabolism during Stress

Kim, H. S., Patel, K., Muldoon-Jacobs, K., Bisht, K. S., Aykin-Burns, N., Pennington, J. D., van der Meer, R., Nguyen, P., Savage, J., Owens, K. M., Vassilopoulos, A., Ozden, O., Park, S. H., Singh, K. K., Abdulkadir, S. A., Spitz, D. R., Deng, C. X. & Gius, D., Jan 19 2010, In : Cancer Cell. 17, 1, p. 41-52 12 p.

Research output: Contribution to journalArticle

520 Scopus citations
2009

Interactions between cells with distinct mutations in c-MYC and Pten in prostate cancer

Kim, J., Eltoum, I. E. A., Roh, M., Wang, J. & Abdulkadir, S. A., Jul 2009, In : PLoS genetics. 5, 7, e1000542.

Research output: Contribution to journalArticle

41 Scopus citations
2008

A role for polyploidy in the tumorigenicity of Pim-1-expressing human prostate and mammary epithelial cells

Roh, M., Franco, O. E., Hayward, S. W., van der Meer, R. & Abdulkadir, S. A., Jul 2 2008, In : PloS one. 3, 7, e2572.

Research output: Contribution to journalArticle

31 Scopus citations
2007

Haploinsufficient prostate tumor suppression by Nkx3.1: A role for chromatin accessibility in dosage-sensitive gene regulation

Mogal, A. P., Van Der Meer, R., Crooke, P. S. & Abdulkadir, S. A., Aug 31 2007, In : Journal of Biological Chemistry. 282, 35, p. 25790-25800 11 p.

Research output: Contribution to journalArticle

23 Scopus citations
2006
52 Scopus citations

Enhanced EGR1 activity promotes the growth of prostate cancer cells in an androgen-depleted environment

Yang, S. Z., Eltoum, I. A. & Abdulkadir, S. A., Apr 15 2006, In : Journal of Cellular Biochemistry. 97, 6, p. 1292-1299 8 p.

Research output: Contribution to journalArticle

33 Scopus citations

Transgenic mice for Cre-inducible overexpression of the oncogenes c-MYC and Pim-1 in multiple tissues

Roh, M., Kim, J., Song, C., Wills, M. & Abdulkadir, S. A., Oct 1 2006, In : Genesis. 44, 10, p. 447-453 7 p.

Research output: Contribution to journalArticle

7 Scopus citations
2005

Chromosomal instability induced by Pim-1 is passage-dependent and associated with dysregulation of cyclin B1

Roh, M., Song, C., Kim, J. & Abdulkadir, S. A., Dec 9 2005, In : Journal of Biological Chemistry. 280, 49, p. 40568-40577 10 p.

Research output: Contribution to journalArticle

27 Scopus citations
32 Scopus citations
2004

A novel time-course cDNA microarray analysis method identifies genes associated with the development of cisplatin resistance

Whiteside, M. A., Chen, D. T., Desmond, R. A., Abdulkadir, S. A. & Johanning, G. L., Jan 22 2004, In : Oncogene. 23, 3, p. 744-752 9 p.

Research output: Contribution to journalArticle

32 Scopus citations

Interaction of Nkx3.1 and p27kip1 in Prostate Tumor Initiation

Gary, B., Azuero, R., Mohanty, G. S., Bell, W. C., Eltoum, I. E. A. & Abdulkadir, S. A., May 2004, In : American Journal of Pathology. 164, 5, p. 1607-1614 8 p.

Research output: Contribution to journalArticle

27 Scopus citations

Notch Signaling and ERK Activation Are Important for the Osteomimetic Properties of Prostate Cancer Bone Metastatic Cell Lines

Zayzafoon, M., Abdulkadir, S. A. & McDonald, J. M., Jan 30 2004, In : Journal of Biological Chemistry. 279, 5, p. 3662-3670 9 p.

Research output: Contribution to journalArticle

111 Scopus citations
2003

Early growth response gene 1 modulates androgen receptor signaling in prostate carcinoma cells

Yang, S. Z. & Abdulkadir, S. A., Oct 10 2003, In : Journal of Biological Chemistry. 278, 41, p. 39906-39911 6 p.

Research output: Contribution to journalArticle

52 Scopus citations

Haploinsufficiency at the Nkx3.1 locus: A paradigm for stochastic, dosage-sensitive gene regulation during tumor initiation

Magee, J. A., Abdulkadir, S. A. & Milbrandt, J., Mar 2003, In : Cancer Cell. 3, 3, p. 273-283 11 p.

Research output: Contribution to journalArticle

109 Scopus citations

Overexpression of the Oncogenic Kinase Pim-1 Leads to Genomic Instability

Roh, M., Gary, B., Song, C., Said-Al-Naief, N., Tousson, A., Kraft, A., Eltoum, I. E. & Abdulkadir, S. A., Dec 1 2003, In : Cancer Research. 63, 23, p. 8079-8084 6 p.

Research output: Contribution to journalArticle

72 Scopus citations
2002

Conditional loss of Nkx3.1 in adult mice induces prostatic intraepithelial neoplasia

Abdulkadir, S. A., Magee, J. A., Peters, T. J., Kaleem, Z., Naughton, C. K., Humphrey, P. A. & Milbrandt, J., 2002, In : Molecular and cellular biology. 22, 5, p. 1495-1503 9 p.

Research output: Contribution to journalArticle

180 Scopus citations
2001

Frequent and early loss of the EGR1 corepressor NAB2 in human prostate carcinoma

Abdulkadir, S. A., Carbone, J. M., Naughton, C. K., Humphrey, P. A., Catalona, W. J. & Milbrandt, J., Jan 1 2001, In : Human pathology. 32, 9, p. 935-939 5 p.

Research output: Contribution to journalArticle

54 Scopus citations

Impaired prostate tumorigenesis in Egr1-deficient mice

Abdulkadir, S. A., Qu, Z., Garabedian, E., Song, S. K., Peters, T. J., Svaren, J., Carbone, J. M., Naughton, C. K., Catalona, W. J., Ackerman, J. J. H., Gordon, J. I., Humphrey, P. A. & Milbrandt, J., 2001, In : Nature Medicine. 7, 1, p. 101-107 7 p.

Research output: Contribution to journalArticle

148 Scopus citations

Quantitative amplification of genomic DNA from histological tissue sections after staining with nuclear dyes and laser capture microdissection

Ehrig, T., Abdulkadir, S. A., Dintzis, S. M., Milbrandt, J. & Watson, M. A., Jan 1 2001, In : Journal of Molecular Diagnostics. 3, 1, p. 22-25 4 p.

Research output: Contribution to journalArticle

55 Scopus citations
2000

EGR1 target genes in prostate carcinoma cells identified by microarray analysis

Svaren, J., Ehrig, T., Abdulkadir, S. A., Ehrengruber, M. U., Watson, M. A. & Milbrandt, J., Dec 8 2000, In : Journal of Biological Chemistry. 275, 49, p. 38524-38531 8 p.

Research output: Contribution to journalArticle

159 Scopus citations

Tissue factor expression and angiogenesis in human prostate carcinoma

Abdulkadir, S. A., Carvalhal, G. F., Kaleem, Z., Kisiel, W., Humphrey, P. A., Catalona, W. J. & Milbrandt, J., Jan 1 2000, In : Human pathology. 31, 4, p. 443-447 5 p.

Research output: Contribution to journalArticle

125 Scopus citations