Grants per year
Personal profile
Research Interests
My research interests center on better understanding the cellular and molecular building blocks that make up the basal ganglia macrocircuit as well as their implications on neural activity level, pattern and plasticity in the basal ganglia in health and disease. My long-term research goal is to elucidate cellular components involved in the pathophysiology and motor symptoms of Parkinson's disease and other related disorders. We hope to translate our insight into developing novel treatments for neurological disorders of the basal ganglia such as Parkinson's disease.
Education/Academic qualification
PhD, Physiology, Chinese University of Hong Kong
… → 2001
Research interests keywords
- Biophysics
- Cellular Electrophysiology
- Electrophysiology
- Gene Therapy
- Ion Channels
- Nervous System Diseases
- Neuroscience
- Physiology
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Investigation of Pallidal Neurons in Motor Inhibition
Chan, S. (PD/PI), Kennedy, A. (Co-Investigator), Parker, J. G. (Co-Investigator) & Xenias, H. S. (Co-Investigator)
National Institute of Neurological Disorders and Stroke
2/20/24 → 1/31/28
Project: Research project
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Predoctoral and Postdoctoral Training Program in Aging and Dementia
Vassar, R. J. (PD/PI), Vassar, R. J. (PD/PI), Weintraub, S. (PD/PI), Weintraub, S. (PD/PI), Allada, R. (Other), Allada, R. (Other), Bevan, M. D. (Other), Bevan, M. D. (Other), Caraveo Piso, G. (Other), Caraveo Piso, G. (Other), Carvill, G. L. (Other), Carvill, G. L. (Other), Chan, S. (Other), Chan, S. (Other), Contractor, A. (Other), Contractor, A. (Other), Disterhoft, J. F. (Other), Disterhoft, J. F. (Other), Dombeck, D. A. (Other), Dombeck, D. A. (Other), Dong, H. (Other), Dong, H. (Other), Ferreira, A. B. (Other), Ferreira, A. B. (Other), Flanagan, M. E. (Other), Flanagan, M. E. (Other), Gefen, T. D. (Other), Gefen, T. D. (Other), Geula, C. (Other), Geula, C. (Other), Gratton, C. (Other), Gratton, C. (Other), He, C. (Other), He, C. (Other), Kahnt, T. (Other), Kahnt, T. (Other), Kalb, R. G. (Other), Kalb, R. G. (Other), Kennedy, A. (Other), Kennedy, A. (Other), Kessler, J. (Other), Kessler, J. (Other), Kiskinis, E. (Other), Kiskinis, E. (Other), Klein, W. L. (Other), Klein, W. L. (Other), Kozorovitskiy, Y. (Other), Kozorovitskiy, Y. (Other), Krainc, D. (Other), Krainc, D. (Other), Li, L. (Other), Li, L. (Other), Mazzulli, J. (Other), Mazzulli, J. (Other), Mesulam, M.-M. (Other), Mesulam, M.-M. (Other), Miller, R. J. (Other), Miller, R. J. (Other), Morimoto, R. I. (Other), Morimoto, R. I. (Other), Opal, P. (Other), Opal, P. (Other), Ozdinler, H. (Other), Ozdinler, H. (Other), Paller, K. (Other), Paller, K. (Other), Parisiadou, L. (Other), Parisiadou, L. (Other), Penzes, P. (Other), Penzes, P. (Other), Pinto, L. (Other), Pinto, L. (Other), Prakriya, M. (Other), Prakriya, M. (Other), Reber, P. J. (Other), Reber, P. J. (Other), Roberts, A. L. (Other), Roberts, A. L. (Other), Rogalski, E. (Other), Rogalski, E. (Other), Savas, J. N. (Other), Savas, J. N. (Other), Surmeier Jr, D. J. (Other), Surmeier Jr, D. J. (Other), Swanson, G. T. (Other), Swanson, G. T. (Other), Voss, J. L. (Other), Voss, J. L. (Other), Zee, P. C. (Other), Zee, P. C. (Other), Zelano, C. (Other) & Zelano, C. (Other)
5/1/22 → 4/30/27
Project: Research project
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Investigation of Pallidal Neurons in Motor Inhibition
Chan, S. (PD/PI), Cui, Q. (Co-Investigator) & Xenias, H. S. (Co-Investigator)
National Institute of Neurological Disorders and Stroke
5/1/22 → 2/14/24
Project: Research project
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Astrocytic regulation of neuronal function in the external globus pallidus
Chan, S. (PD/PI)
6/30/21 → 7/31/23
Project: Research project
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Transformation of the stress response into motor behavior by the external globus pallidus
Chan, S. (PD/PI)
University of Texas Health Science Center at Houston, National Institute of Mental Health
6/5/17 → 3/31/22
Project: Research project
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Neuronal PAS domain 1 identifies a major subpopulation of wakefulness-promoting GABAergic neurons in the basal forebrain
Troppoli, T. A., Yang, C., Katsuki, F., Uygun, D. S., Lin, I., Aguilar, D. D., Spratt, T., Basheer, R., McNally, J. M., Chan, C. S., McKenna, J. T. & Brown, R. E., May 21 2024, In: Proceedings of the National Academy of Sciences of the United States of America. 121, 21, e2321410121.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
A non-canonical striatopallidal Go pathway that supports motor control
Labouesse, M. A., Torres-Herraez, A., Chohan, M. O., Villarin, J. M., Greenwald, J., Sun, X., Zahran, M., Tang, A., Lam, S., Veenstra-VanderWeele, J., Lacefield, C. O., Bonaventura, J., Michaelides, M., Chan, C. S., Yizhar, O. & Kellendonk, C., Dec 2023, In: Nature communications. 14, 1, 6712.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Cell and circuit complexity of the external globus pallidus
Courtney, C. D., Pamukcu, A. & Chan, C. S., Jul 2023, In: Nature neuroscience. 26, 7, p. 1147-1159 13 p.Research output: Contribution to journal › Review article › peer-review
13 Scopus citations -
Cell type-specific processing of non-motor signals in the external pallidum
Courtney, C. D. & Chan, C. S., May 2023, In: Trends in Neurosciences. 46, 5, p. 336-337 2 p.Research output: Contribution to journal › Short survey › peer-review
Open Access -
Histone deacetylase inhibitors mitigate antipsychotic risperidone-induced motor side effects in aged mice and in a mouse model of Alzheimer’s disease
Rodriguez, G., Fisher, D. W., McClarty, B., Montalvo-Ortiz, J., Cui, Q., Chan, C. S. & Dong, H., Jan 6 2023, In: Frontiers in Psychiatry. 13, 1020831.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations