Grants per year
Personal profile
Research Interests
My research interests center on better understanding the cellular and molecular building blocks that make up the basal ganglia macrocircuit as well as their implications on neural activity level, pattern and plasticity in the basal ganglia in health and disease. My long-term research goal is to elucidate cellular components involved in the pathophysiology and motor symptoms of Parkinson's disease and other related disorders. We hope to translate our insight into developing novel treatments for neurological disorders of the basal ganglia such as Parkinson's disease.
Education/Academic qualification
PhD, Chinese University of Hong Kong
… → 2001
Research interests
- Biophysics
- Cellular Electrophysiology
- Electrophysiology
- Gene Therapy
- Ion Channels
- Nervous System Diseases
- Neuroscience
- Physiology
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Grants
GABAergic Signaling in the External Globus Pallidus
National Institute of Neurological Disorders and Stroke
2/1/17 → 1/31/22
Project: Research project
LRRK2-mediated molecular and synaptic events in the striatum
National Institute of Neurological Disorders and Stroke
8/15/16 → 7/31/21
Project: Research project
Age-Related Histone Modification Effect on Antipsychotic Action
Chan, S., Csernansky, J. G., Dong, H., Fang, D. & Meltzer, H. Y.
National Institute of Mental Health
5/26/16 → 2/28/21
Project: Research project
2017 HHMI-PF Medical Research Fellows Award
Howard Hughes Medical Institute
5/1/17 → 5/31/20
Project: Research project
Research Output
Npas1+-Nkx2.1+ Neurons Are an Integral Part of the Cortico-pallido-cortical Loop
Abecassis, Z. A., Berceau, B. L., Win, P. H., García, D., Xenias, H. S., Cui, Q., Pamukcu, A., Cherian, S., Hernández, V. M., Chon, U., Lim, B. K., Kim, Y., Justice, N. J., Awatramani, R., Hooks, B. M., Gerfen, C. R., Boca, S. M. & Chan, C. S., Jan 22 2020, In : The Journal of neuroscience : the official journal of the Society for Neuroscience. 40, 4, p. 743-768 26 p.Research output: Contribution to journal › Article
3
Scopus
citations
PRISM: A Progenitor-Restricted Intersectional Fate Mapping Approach Redefines Forebrain Lineages
Poulin, J. F., Luppi, M. P., Hofer, C., Caronia, G., Hsu, P. K., Chan, C. S. & Awatramani, R., Jun 22 2020, In : Developmental Cell. 53, 6, p. 740-753.e3Research output: Contribution to journal › Article
Open Access
Mutant huntingtin enhances activation of dendritic Kv4 K+ channels in striatal spiny projection neurons
Carrillo-Reid, L., Day, M., Xie, Z., Melendez, A. E., Kondapalli, J., Plotkin, J. L., Wokosin, D. L., Chen, Y., Kress, G. J., Kaplitt, M., Ilijic, E., Guzman, J. N., Chan, C. S. & Surmeier, D. J., Apr 2019, In : eLife. 8, e40818.Research output: Contribution to journal › Article
Open Access
5
Scopus
citations
Mapping projections of molecularly defined dopamine neuron subtypes using intersectional genetic approaches
Poulin, J. F., Caronia, G., Hofer, C., Cui, Q., Helm, B., Ramakrishnan, C., Chan, C. S., Dombeck, D. A., Deisseroth, K. & Awatramani, R., Sep 1 2018, In : Nature Neuroscience. 21, 9, p. 1260-1271 12 p.Research output: Contribution to journal › Article
48
Scopus
citations
Paraventricular hypothalamic and amygdalar CRF neurons synapse in the external globus pallidus
Hunt, A. J., Dasgupta, R., Rajamanickam, S., Jiang, Z., Beierlein, M., Chan, C. S. & Justice, N. J., Jul 1 2018, In : Brain Structure and Function. 223, 6, p. 2685-2698 14 p.Research output: Contribution to journal › Article
7
Scopus
citations