Grants per year
Personal profile
Research Interests
My research interests center on better understanding the cellular and molecular building blocks that make up the basal ganglia macrocircuit as well as their implications on neural activity level, pattern and plasticity in the basal ganglia in health and disease. My long-term research goal is to elucidate cellular components involved in the pathophysiology and motor symptoms of Parkinson's disease and other related disorders. We hope to translate our insight into developing novel treatments for neurological disorders of the basal ganglia such as Parkinson's disease.
Education/Academic qualification
PhD, Chinese University of Hong Kong
… → 2001
Research interests
- Biophysics
- Cellular Electrophysiology
- Electrophysiology
- Gene Therapy
- Ion Channels
- Nervous System Diseases
- Neuroscience
- Physiology
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Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Astrocytic regulation of neuronal function in the external globus pallidus
6/30/21 → 6/30/23
Project: Research project
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GABAergic Signaling in the External Globus Pallidus
National Institute of Neurological Disorders and Stroke
2/1/17 → 1/31/22
Project: Research project
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LRRK2-mediated molecular and synaptic events in the striatum
National Institute of Neurological Disorders and Stroke
8/15/16 → 7/31/22
Project: Research project
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Age-Related Histone Modification Effect on Antipsychotic Action
Dong, H., Chan, S., Csernansky, J. G., Fang, D. & Meltzer, H. Y.
National Institute of Mental Health
5/26/16 → 2/28/22
Project: Research project
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Dissociable roles of pallidal neuron subtypes in regulating motor patterns
Cui, Q., Pamukcu, A., Cherian, S., Chang, I. Y. M., Berceau, B. L., Xenias, H. S., Higgs, M. H., Rajamanickam, S., Chen, Y., Du, X., Zhang, Y., McMorrow, H., Abecassis, Z. A., Boca, S. M., Justice, N. J., Wilson, C. J. & Chan, C. S., May 5 2021, In: Journal of Neuroscience. 41, 18, p. 4036-4059 24 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Optogenetic activation of muscle contraction in vivo
Ganji, E., Chan, C. S., Ward, C. W. & Killian, M. L., 2021, In: Connective tissue research. 62, 1, p. 15-23 9 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
Periodic unitary synaptic currents in the mouse globus pallidus during spontaneous firing in slices
Higgs, M. H., Jones, J. A., Chan, C. S. & Wilson, C. J., Apr 2021, In: Journal of neurophysiology. 125, 4, p. 1482-1500 19 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Striatal direct pathway targets Npas1+pallidal neurons
Cui, Q., Du, X., Chang, I. Y. M., Pamukcu, A., Lilascharoen, V., Berceau, B. L., García, D., Hong, D., Chon, U., Narayanan, A., Kim, Y., Lim, B. K. & Chan, C. S., May 5 2021, In: Journal of Neuroscience. 41, 18, p. 3966-3987 22 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
Npas1+-Nkx2.1+ Neurons Are an Integral Part of the Cortico-pallido-cortical Loop
Abecassis, Z. A., Berceau, B. L., Win, P. H., García, D., Xenias, H. S., Cui, Q., Pamukcu, A., Cherian, S., Hernández, V. M., Chon, U., Lim, B. K., Kim, Y., Justice, N. J., Awatramani, R., Hooks, B. M., Gerfen, C. R., Boca, S. M. & Chan, C. S., Jan 22 2020, In: The Journal of neuroscience : the official journal of the Society for Neuroscience. 40, 4, p. 743-768 26 p.Research output: Contribution to journal › Article › peer-review
21 Scopus citations